| Budget Amount *help |
¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2011: ¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
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| Research Abstract |
The present study was desiged to identify the urinary biomarker to predict the pathogenesis of hypertension. We enrolled incoming freshmen of our university and adults who have taken health checkup in Kawasaki town in Miyagi in 2011. Urinary excertion of angiotensinogen (AGT), inflammation markers, oxidative stress markers and carbonyl compounds and serum AGT, inflammation markers levels were analyzed. The present study determined the association between blood pressure and uriary AGT and inflammation markers excretion in young obese adults. From multiple linear regression analysis, urinary AGT excretion was significantly associated with blood pressure in adults.
This study suggested that urinary AGT excretion would predicte the pathogenesis of hypertension inyoung obase adults.
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