| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
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| Research Abstract |
It is known that interaction of circadian clock and feeding/nutrition as for chrono-nutrition, and of circadian clock and exercise as for chrono-exercise. Combination of chrono-nutriton and chrono-exercise could determine the phase of liver circadian clock; 2 meals (morning and evening) per day advanced the liver rhythm, but wheel running in the morning attenuated the phase advance. Exercise in the evening rather than in the morning attenuated high fat diet-induced obesity with increasing energy metabolism. Feeding/exercise caused anti-obesity effect than exercise/feeding, suggesting that combination of timing of exercise/feeding is critical for anti-obesity.
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