| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2013: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2012: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2011: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
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| Research Abstract |
Cellular morphology of tissue stem cells is dramatically changed during the differentiation process from progenitors toward matures. The interaction between plasma membranes and cytoskeletons, the structural networks of actin-based membrane skeleton, caveolae, and clathrin-coated pits at the interface with the plasma membrane play crucial roles. By rapid-freeze, freeze-replica electron microscopy, we carefully visualized the cytoplasmic surface of those structures, and particularly got the novel findings about caveolar filaments and crescent-like structures. Also the other researches regarding the plasma membrane differentiation are going on.
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