| Budget Amount *help |
¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2013: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2012: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2011: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Outline of Final Research Achievements |
Living organism reads the same genome sequence variably to create a variety of cell types. To read the same genome differentially, many organisms including human exploits a mechanism termed methylation, which chemically marks the genomic letter called “cytosine” located in particular locations in the genome. Recent studies revealed that the orgamisms also use hydroxymethylation to mark their genomes. In this study, we developed methods to reveal the positions of hydroxymethylation in the genome.
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