Intracellular glycoside signal participating in the regulation of biological phenomena
Project/Area Number |
23310147
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Living organism molecular science
|
Research Institution | Tohoku University |
Principal Investigator |
UEDA Minoru 東北大学, 理学(系)研究科(研究院), 教授 (60265931)
|
Project Period (FY) |
2011-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
Fiscal Year 2013: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2012: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2011: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
|
Keywords | 就眠運動 / ジャスモン酸グルコシド / 配糖体 / シグナル伝達 / ケミカルバイオロジー / ジャスモン酸 / ジャスモン酸配糖体 / 活性酸素 / グリコシド / 標的タンパク質 / Glycosylation Switching / 標的タンパク / cDNAライブラリー |
Research Abstract |
JAG induced motor cell shrinking and concomittant ROS production. External addition of ROS also induced motor-cell shrinking, thne JAG-induced shrinking of motor cell is independent to COI1-JAZ signaling pathway and dependent ROS-mediated path. The molecular target of JAG was also revealed by using our compact molecular probe approach.
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Report
(4 results)
Research Products
(44 results)
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[Journal Article] Creation of Pure Nanodrugs and Their Anticancer PropertiesAngew2012
Author(s)
H. Kasai, T. Murakami, Y. Ikuta, Y. Koseki, K. Baba, H. Oikawa, H. Nakanishi, M. Okada, M. Shoji, M. Ueda, H. Imahori, M. Hashida
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Journal Title
Chem. Int. Ed
Volume: 51
Pages: 10315-10318
Related Report
Peer Reviewed
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[Journal Article] Hybrid Stereoisomers of Compact Molecular Probes Based on Jasmonic Acid Glucoside: Syntheses and Biological Evaluations,2012
Author(s)
M. Ueda, G. Yang, Y. Ishimaru, S. Tamura, T. Itabashi, K. Kiyota, S. Kuwahara, S. Inomata, M. Shoji, T. Sugai
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Journal Title
Bioorg. Med. Chem.,
Volume: 20
Pages: 5832-5843
Related Report
Peer Reviewed
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[Journal Article] Creation of Pure Nanodrugs and Their Anticancer Properties2012
Author(s)
H. Kasai, T. Murakami, Y. Ikuta, Y. Koseki, K. Baba, H. Oikawa, H. Nakanishi, M. Okada, M. Shoji, M. Ueda, H. Imahori, M. Hashida
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Journal Title
Angew. Chem. Int. Ed.
Volume: 51
Pages: 10315-10318
Related Report
Peer Reviewed
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