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脳機能画像手法に基づく触の錯覚の検討と解離性離隔の臨床治療への実証的試み

Research Project

Project/Area Number 23330218
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Experimental psychology
Research InstitutionRikkyo University

Principal Investigator

鍋田 恭孝  立教大学, 公私立大学の部局等, 教授 (60297075)

Co-Investigator(Kenkyū-buntansha) 長田 佳久  立教大学, 名誉教授, 名誉教授 (00133455)
本間 元康  独立行政法人国立精神・神経医療研究センター, 精神保健研究所成人精神保健研究部, 研究員 (20434194)
小山 慎一  千葉大学, 工学(系)研究科(研究院), 准教授 (40420913)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Declined (Fiscal Year 2013)
Budget Amount *help
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2013: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2011: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Keywords感覚間統合 / ラバーハンドイリュージョン / 記憶学習 / 解離 / 自己所有感 / 位置感覚 / 触痛覚 / 心理物理学 / 脳メカニズム
Research Abstract

本研究は,心理学,医学,工学,哲学が連携し,感覚間統合という現象から解離と呼ばれる精神病理の治療可能性までを研究対象としたトランスレーショナル研究である.精神医学領域では,統合失調症の一症状として,自己同一性を喪失する解離という精神病理が報告されており,自己意識に関わる「触知覚」の基本原理が深く関与している可能性がある.認知科学の中で蓄積されてきた感覚間統合の知見を元に,解離の精神病理学的メカニズムを脳機能画像法などの神経科学的手法を用いて解明し,最終的に臨床応用に役立てることを目的としている.本年度では,触感覚の錯覚が視覚的錯覚と連鎖的に生じるラバーハンド(RH)イリュージョン学習を3日間連続で行い,感覚間統合の錯覚学習における自己所有感と位置感覚の変容プロセスを検討した.その結果,全日において,学習後にRHへの自己所有感の増加および位置感覚のドリフトが認められ,従来のRHイリュージョンを再現する結果となったが,自己所有感のデフォルト評定値は日毎に低下し,位置感覚のデフォルト評定値は日毎に増加した.矛盾した感覚を引き起こす仮想現実的な環境では,RHを自身の手だと受容することは拒みながらも,位置感覚は視覚的RHに依存しながら変容していくことが示唆され,少なくとも,自己所有感と位置感覚の長期的学習メカニズムに異なる神経可塑性プロセスが関与していると考えられる(論文投稿中).現在は脳機能画像分析法(functional Magnetic Resonance Imaging: fMRI)を用いた実験を開始し,分析中である.また本プロジェクトの着想に至るもととなった研究を論文化した.

Current Status of Research Progress
Reason

翌年度、交付申請を辞退するため、記入しない。

Strategy for Future Research Activity

翌年度、交付申請を辞退するため、記入しない。

Report

(2 results)
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (28 results)

All 2013 2012 2011 Other

All Journal Article (12 results) (of which Peer Reviewed: 10 results) Presentation (15 results) (of which Invited: 3 results) Book (1 results)

  • [Journal Article] Hyper-volume of eye-contact perception and social anxiety traits.2013

    • Author(s)
      Motoyasu Honma
    • Journal Title

      Consciousness and Cognition

      Volume: 22 Issue: 1 Pages: 167-173

    • DOI

      10.1016/j.concog.2012.12.002

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Valproic acid but not D-cycloserine facilitates sleep-dependent offline learning of extinction and habituation of conditioned fear in humans.2013

    • Author(s)
      Kenichi Kuriyama, Motoyasu Honma, Takuya Yoshiike, Yoshiharu Kim
    • Journal Title

      Neuropharmacology

      Volume: 64 Pages: 424-431

    • DOI

      10.1016/j.neuropharm.2012.07.045

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spatial range of perceptual gaze congruency.2013

    • Author(s)
      Daisuke Kuribayashi, Motoyasu Honma, Yoshihisa Osada
    • Journal Title

      The Japanese Journal of Psychonomic Science

      Volume: 31 Pages: 95-96

    • Related Report
      2012 Annual Research Report
  • [Journal Article] アイコンタクト知覚範囲の性差に関する探索的検討: 社交性不安およびアイコンタクト相手の性別の影響.2013

    • Author(s)
      松田昌史・本間元康・石井亮・熊野史朗・大塚和弘・大和淳司
    • Journal Title

      信学技報

      Volume: 112 Pages: 77-82

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 単一特徴への注意が変化検出に与える効果2013

    • Author(s)
      村越琢磨・久雅子・増田知尋・和田有史・長田佳久
    • Journal Title

      Vision,

      Volume: 25(1) Pages: 8-19

    • NAID

      130007537261

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Disturbances in equilibrium function after major earthquake.2012

    • Author(s)
      Motoyasu Honma, Nobutaka Endo, Yoshihisa Osada, Yoshiharu Kim, Kenichi Kuriyama.
    • Journal Title

      Scientific Reports

      Volume: 2 Issue: 1 Pages: 1-8

    • DOI

      10.1038/srep00749

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Perceptual and not physical eye contact elicits pupillary dilation2012

    • Author(s)
      M Honma, Y Tanaka, Y Osada, K Kuriyama
    • Journal Title

      Biological Psychology

      Volume: 89 Issue: 1 Pages: 112-116

    • DOI

      10.1016/j.biopsycho.2011.09.016

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Is this a new type of primary prosopagnosia, both progressiveand apperceptive?2012

    • Author(s)
      Azusa Sugimoto, Shinichi Koyama, Akira Midorikawa, Akinori Futamura, Kiichi Ishiwata, Kenji Ishii, Michael W.Miller, Mitsuru Kawamura
    • Journal Title

      Neuropsychiatric Disease and Treatment, accepted

      Volume: 8 Pages: 69-73

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An N-methyl-D-aspartate receptor agonist facilitates sleep-independent synaptic plasticity associated with working memory capacity enhancement2011

    • Author(s)
      Kuriyama K, Honma M, Shimazaki M, Horie M, Yoshiike T, Koyama S, Kim Y.
    • Journal Title

      Scientific Reports

      Volume: 1 Issue: 1 Pages: 127-127

    • DOI

      10.1038/srep00127

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of D-cycloserine and valproic acid on the extinction of reinstated fear-conditioned responses and habituation of fear conditioning in healthy humans2011

    • Author(s)
      K. Kuriyama, M. Honma, T. Soshi, T. Fujii, Y. Kim
    • Journal Title

      Psychopharmacology

      Volume: 218(3) Issue: 3 Pages: 589-597

    • DOI

      10.1007/s00213-011-2353-x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] D-cycloserine facilitates procedural learning but not declarative learning in healthy humans : a randomized controlled Trial of the effect of D-cycloserine and valproic acid on overnight properties in the performance of non-emotional memory tasks2011

    • Author(s)
      Kuriyama K, Honma M, Koyama S, Kim Y
    • Journal Title

      Neurobiology of Learning & Memory

      Volume: 95 Issue: 4 Pages: 505-509

    • DOI

      10.1016/j.nlm.2011.02.017

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Attention deficits in Japanese multiple sclerosis patients with minor brain lesion loads2011

    • Author(s)
      Akitoshi Takeda, Masashi Nakajima, Mutsutaka Kobayakawa, Natsuko Tsuruya, Shinichi Koyama, Takami Miki, Mitsuru Kawamura
    • Journal Title

      Neuropsychiatric Disease and Treatment

      Volume: 7 Pages: 745-751

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 視覚刺激が平衡感覚に与える影響-片頭痛患者と健常群の比較2013

    • Author(s)
      今泉修,李晴香,本間元康,日比野治雄,小山慎一
    • Organizer
      第46回知覚コロキウム
    • Place of Presentation
      東京都青梅市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 理想的な人形顔は制作者の顔に似るのか2012

    • Author(s)
      若松くるみ, 日比野治雄, 小山慎一
    • Organizer
      第7回日本感性工学会春季大会
    • Place of Presentation
      高松市
    • Year and Date
      2012-03-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 進行性相貌失認:posterior cortical atrophy (PCA)の自験例とsemantic dementia (SD)の比較2011

    • Author(s)
      杉本あずさ, 小山慎一, 緑川晶, 二村明徳, 河村満
    • Organizer
      第35回日本高次脳機能障害学会学術総会
    • Place of Presentation
      鹿児島市
    • Year and Date
      2011-11-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] Sleep extinguishes false perception acquired by learning of visual-tactile integration2011

    • Author(s)
      M Honma, T Yoshiike, M Shimazaki, S Koyama, M Kimura, Y Kim, K Kuriyama
    • Organizer
      Worldsleep2011
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2011-10-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] 図と地の分化の障害に起因する運動視の自覚的困難がみられた成人型Krabbe病35歳女性例2011

    • Author(s)
      武田景敏, 小山慎一, 嶋田裕之, 山川義宏, 竹内潤, 山本圭一, 田村暁子, 伊藤和博, 安宅鈴香, 正木秀樹, 蔦田強司, 三木隆己
    • Organizer
      第35回日本神経心理学会総会
    • Place of Presentation
      宇都宮市
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Gaze sensitivity for own face2011

    • Author(s)
      D Kuribayashi, M Honma, Y Osada, Y Tanaka
    • Organizer
      Vision Science Society 11th Annual Meeting
    • Place of Presentation
      Naple, USA
    • Year and Date
      2011-05-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 進行性相貌失認2011

    • Author(s)
      杉本あずさ, 小山慎一, 緑川晶, 二村明徳, 河村満
    • Organizer
      2011年度「包括脳ネットワーク」夏のワークショップ
    • Place of Presentation
      神戸市
    • Related Report
      2011 Annual Research Report
  • [Presentation] コミュニケーションスキルと足踏みの自発的同期

    • Author(s)
      永井聖剛・本間元康・熊田孝恒・長田佳久
    • Organizer
      日本認知科学会
    • Place of Presentation
      仙台国際センター
    • Related Report
      2012 Annual Research Report
  • [Presentation] 東日本大震災における平衡感覚機能の異常

    • Author(s)
      本間元康
    • Organizer
      日本心理学会
    • Place of Presentation
      専修大学
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] An NMDA receptor agonist boosts sleep-independent synaptic plasticity associated with enhancement of working memory capacity

    • Author(s)
      Kenichi Kuriyama, Motoyasu Honma, Takuya Yoshiike, Yoshiharu Kim
    • Organizer
      Associated Professional Sleep Societies
    • Place of Presentation
      Massachusetts, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] 日中位相の覚醒区間における反応抑制学習の増強

    • Author(s)
      本間元康・吉池卓也・金吉晴・栗山健一
    • Organizer
      日本睡眠学会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Annual Research Report
  • [Presentation] 巨大地震後におこる平衡感覚異常

    • Author(s)
      本間元康・遠藤信貴・長田佳久・金吉晴・栗山健一
    • Organizer
      日本認知心理学会
    • Place of Presentation
      岡山大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] Phenomenology of “Being Stated At” and of Vulnerability”

    • Author(s)
      河野哲也
    • Organizer
      Intersubjectivity Workshop
    • Place of Presentation
      Tokai University,
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Extended mind and the phenomenology of self-boundary

    • Author(s)
      河野哲也
    • Organizer
      Helsinki University, Finland
    • Place of Presentation
      Helsinki University, Finland
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Affordances and Extended Mind: An Ecological Theory of Extended Mind

    • Author(s)
      河野哲也
    • Organizer
      The First Conference on Contemporary Philosophy in East Asia
    • Place of Presentation
      Academia Sinica, Taipei.
    • Related Report
      2012 Annual Research Report
  • [Book] Effects of sleep dept on cognitive performance and prefrontal activity in humans. (Infrared Spectroscopy /ISBN: 979-953-307-362-9, Ed. Maja Kisic)2012

    • Author(s)
      Kenichi Kuriyama, Motoyasu Honma
    • Publisher
      InTech
    • Related Report
      2012 Annual Research Report

URL: 

Published: 2011-04-06   Modified: 2024-10-23  

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