Deformation dynamics of composite lipid membranes
| Project/Area Number |
23340121
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biophysics/Chemical physics
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| Research Institution | Kyoto University |
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Principal Investigator |
TANIGUCHI Takashi 京都大学, 工学(系)研究科(研究院), 准教授 (60293669)
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| Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Ryoichi 京都大学, 大学院・工学研究科, 教授 (10263401)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
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| Keywords | 脂質二重膜 / 流体膜 / 相分離 / ベシクル / 多成分脂質膜 / 相転移 / 非対称膜 / ラフト |
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| Research Abstract |
In this project, we have addressed a construction of a minimum theoretical model to describe dynamics of artificial multi-component lipid membranes and vesicles. By using the model, we performed numerical simulations to reveal the physical origin of various phenomena seen in biomembranes from physical points of view. We investigated various membrane systems (for example, dynamics of a pore-rim-rolled vesicle, effect of hydrodynamic flow inside and outside of vesicle and effect of intra-membrane hydrodynamics on their dynamics, and effect of asymmetric distribution of stress between two leaflets in lipid bilayer) , where intra-membrane degree of freedom play essential role.
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Report
(4 results)
Research Products
(48 results)
