| Project/Area Number |
23340176
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plasma science
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| Research Institution | Osaka University |
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Principal Investigator |
KITANO Katsuhisa 大阪大学, 工学(系)研究科(研究院), 准教授 (20379118)
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| Co-Investigator(Kenkyū-buntansha) |
SHIRAKI Kentaro 筑波大学, 数理物質科学研究科, 准教授 (90334797)
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| Co-Investigator(Renkei-kenkyūsha) |
TANI Atsushi 大阪大学, 大学院・理学研究科, 助教 (10335333)
IKAWA Satoshi 大阪府立産業技術総合研究所, 主任研究員 (80393297)
ARAKAWA Ryuichi 関西大学, 工学部, 教授 (00127177)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2011: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
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| Keywords | プラズマ医療 / 大気圧低温プラズマ / プラズマ誘起液中反応場 / プラズマ処理水 / プラズマ誘起液中化学プロセス / 大気圧プラズマ / アミロイドβ / アルツハイマー / 液中プラズマプロセス / フリーラジカル / 生体高分子 / プラズマ殺菌 / プラズマバイオ |
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| Research Abstract |
For understanding the reaction processes of low temperature atmospheric pressure plasma to living organism, the research of the reaction between active species and biomacromolecule. As human body is wet condition and active species generated in liquid are important, measuremants of active species in liquid were done. Effects of plasma to amino acid, protein, lipid were evaluated and amyloid beta protein, which cause Alzheimer disease. intracellular oxidation stresses were evaluated using dye included micelle. It was confirmed that increment of oxidative stress was increased with the reduced pH methods.
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