Selection of geometric isomer of biomolecules and study of multi-dimensional steric effect on collisional isomerization reaction

• Project/Area Number: 23350008
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Physical chemistry
• Research Institution: Osaka University
• Principal Investigator: OHOYAMA Hiroshi 大阪大学, 理学(系)研究科(研究院), 准教授 (60192522)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥20,800,000 (Direct Cost: ¥16,000,000、Indirect Cost: ¥4,800,000); Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2011: ¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
• Keywords: 立体異性体 / シュタルク効果 / 異性体選別 / 生体分子 / 異性化反応 / 気―液界面 / 構造異性体 / 立体ダイナミクス

Outline of Final Research Achievements

Large Molecules like biomolecules have a large number of geometric isomers which are caused by the change of configuration around the single bonds. It is expected that the steric geometry gives significant effects on the chemical and physical property and the reactivity of large molecules like biological action.
In the present study, we developed a new method to select each steric isomer from the mixture of geometric isomers by using a time and space modulated electric inhomogeneous field. The present study ensures the study on collisional isomerization process from a biomolecule having a well-defined geometry.

Research Products

• [Journal Article] Atomic Alignment Effect on Reactivity and on Product Alignment in the Energy-Transfer Reaction of Oriented Ar (3P2, 4s [3/2]2, MJ = 2) + Kr (4p6,1S0) → Ar (3p6, 1S0) + Kr (5p [3/2]2) (2015)
  • Author(s): H. Ohoyama
  • Journal Title: J. Phys. Chem. A Volume: 119 Issue: 10 Pages: 1820-1829
  • DOI: 10.1021/jp509989x
  • Peer Reviewed
• [Journal Article] Collision Energy Dependent Cross Section and Rotational Alignment of NO (A ) in the Energy Transfer Reaction of N2 (A) + NO (X) → N2 (X) + NO (A ) (2014)
  • Author(s): H. Ohoyama
  • Journal Title: J. Phys. Chem. A Volume: 118 Issue: 41 Pages: 9646-9652
  • DOI: 10.1021/jp507696y
  • Peer Reviewed
• [Journal Article] Vector Correlation between the Alignment of Reactant N2 (A) and the Alignment of Product NO (A) Rotation in the Energy Transfer Reaction of Aligned N2 (Ａ) + NO (X) → NO (A)+ N2 (X) (2013)
  • Author(s): H. Ohoyama
  • Journal Title: J. Chem. Phys. Volume: 139 Issue: 23 Pages: 234308-234308
  • DOI: 10.1063/1.4844315
  • Peer Reviewed
• [Journal Article] Alignment Effect of N2(A3Σu+) in the Energy Transfer Reaction of Aligned N2(A3Σu+) + NO(X2Π) → NO(A2Σ+) + N2(X1Σg+) (2012)
  • Author(s): H. Ohoyama and S. Maruyama
  • Journal Title: J. Phys. Chem. A Volume: 116 Issue: 25 Pages: 6685-6692
  • DOI: 10.1021/jp303735e
  • Peer Reviewed
• [Journal Article] Stereo correlated dynamics in the energy transfer process of aligned N2 (A 3Σu+) + oriented NO (X 2Π, Ω = 1/2) → NO (A 2Σ+) + N2 (X 1Σg+) (2012)
  • Author(s): H. Ohoyama and S. Maruyama
  • Journal Title: J. Chem. Phys. Volume: 137 Issue: 6 Pages: 11-11
  • DOI: 10.1063/1.4739273
  • Peer Reviewed
• [Journal Article] Atomic Alignment Effect in the Dissociative Energy Transfer Reactions of Metal Carbonyls [Fe (CO)5, Ni (CO)4] with Oriented Ar (3P2) (2011)
  • Author(s): H. Ohoyama, Y. Matsuura
  • Journal Title: J. Phys. Chem. A Volume: 115 Issue: 40 Pages: 10888-10893
  • DOI: 10.1021/jp206670w
  • Peer Reviewed
• [Journal Article] Steric Effect in the Energy Transfer Reaction of Oriented CO (a 3Π, v′ = 0, Ω = 1 and 2) + NO (X 2Π) → NO (A 2Σ+, B 2Π) + CO (X 1Σ+) (2011)
  • Author(s): H. Ohoyama, Y. Matsuura
  • Journal Title: J. Phys. Chem. A Volume: 115 Issue: 28 Pages: 8055-8063
  • DOI: 10.1021/jp202781g
  • Peer Reviewed
• [Journal Article] Collision–Induced Harpooning Observed in the Excimer Formation in the Oriented NF3 + Oriented Kr* (3P2, MJ = 2) Reaction (2011)
  • Author(s): Y. Matsuura, H. Ohoyama
  • Journal Title: J. Phys. Chem. A Volume: 115 Issue: 18 Pages: 4583-4591
  • DOI: 10.1021/jp200979r
  • Peer Reviewed
• [Journal Article] Rotationally Correlated Reactivity in the CH (v = 0, J, Fi) + O2 → OH (A) + CO Reaction (2011)
  • Author(s): H. Ohoyama, K. Yamakawa, R. Oda, Y. Nagamachi, T. Kasai
  • Journal Title: J. Chem. Phys. Volume: 134 Issue: 11
  • DOI: 10.1063/1.3560660
  • Peer Reviewed
• [Journal Article] Multi-Dimensional Steric Effect for the XeF* (B, C) Formation in the Oriented Xe* (3P2, MJ = 2) + Oriented NF3 Reaction (2011)
  • Author(s): H. Ohoyama
  • Journal Title: Phys. Chem. Chem. Phys. Volume: 13 Issue: 1 Pages: 182-189
  • DOI: 10.1039/c0cp00648c
  • Peer Reviewed
• [Presentation] イオン液体分子線を用いた気-液界面衝突ダイナミクスの研究 (2014)
  • Author(s): 松浦 裕介,寺本 高啓,大山 浩
  • Organizer: 第８回分子科学討論会
  • Place of Presentation: 広島大学 東広島キャンパス(広島県東広島市）
  • Year and Date: 2014-09-21 – 2014-09-24
• [Presentation] Study on reaction dynamics via the stereo-vector correlations (2014)
  • Author(s): Ｈ． Ｏｈｏｙａｍａ
  • Organizer: 第３０回化学反応討論会
  • Place of Presentation: イ－グレ姫路(兵庫県姫路市）
  • Year and Date: 2014-06-04 – 2014-06-06
• [Presentation] Rg*(3 P2,MJ =2)+NF3反応における多次元立体ダイナミクス (2013)
  • Author(s): 松浦 裕介，大山 浩
  • Organizer: 第7回分子科学討論会
  • Place of Presentation: 京都テルサ（京都府民総合交流プラザ）(京都府京都市）
  • Year and Date: 2013-09-24 – 2013-09-27
• [Presentation] 配向-配向ベクトル相関による多自由度系反応ダイナミクスの研究 (2013)
  • Author(s): 大山 浩，松浦 裕介
  • Organizer: 第7回分子科学討論会
  • Place of Presentation: 京都テルサ（京都府民総合交流プラザ）(京都府京都市）
  • Year and Date: 2013-09-24 – 2013-09-27
• [Presentation] Stereodynamics on chemical reaction using the oriented beams (2013)
  • Author(s): Ｈ． Ｏｈｏｙａｍａ
  • Organizer: 第２９回化学反応討論会
  • Place of Presentation: 東北大学 片平キャンパス(宮城県仙台市）
  • Year and Date: 2013-06-05 – 2013-06-07
  • Invited
• [Presentation] Multi-Dimensional Steric Effect in the Energy Transfer Reaction of Aligned N2 (A3Σu+) + Oriented NO (X 2Π, Ω= 1/2) → NO (A 2Σ+) + N2 (X 1Σg+)
  • Author(s): OHOYAMA Hiroshi; MARUYAMA Satoshi
  • Organizer: 第28回化学反応討論会
  • Place of Presentation: 九州大学
• [Presentation] 配列N2(A3Sigmau+) ＋ 配向NO(X2Pai, Omega=1/2)反応における多次元立体効果
  • Author(s): 大山 浩，丸山 哲士
  • Organizer: 第6回分子科学討論会
  • Place of Presentation: 東京大学
• [Presentation] Steric Effect in the Energy transfer Reaction of Oriented CO (a 3Π, v' = 0, Ω=1&2) + NO (X2Π) → NO (A2Σ+, B2Π) + CO (X1Σ+)
  • Author(s): Ohoyama, Hiroshi; Matsuura, Yusuke
  • Organizer: 第27回化学反応討論会
  • Place of Presentation: 東京工業大学
• [Presentation] Collision–Induced Harpooning Observed in the Excimer Formation in the Oriented NF3 + Oriented Kr* (3P2, MJ = 2) Reaction
  • Author(s): Matsuura, Yusuke, Ohoyama, Hiroshi
  • Organizer: 第27回化学反応討論会
  • Place of Presentation: 東京工業大学