Elucidation of the chemical processes of biological reactions based on the design of novel nano-sized reaction environments

• Project/Area Number: 23350015
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Organic chemistry
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: GOTO Kei 東京工業大学, 理工学研究科, 教授 (70262144)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000); Fiscal Year 2013: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2011: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
• Keywords: 有機化学 / 酵素モデル / 活性中間体 / レドックス制御 / ナノサイズ分子 / 合成化学 / ナノサイエンス / 分子認識 / システインモデル / ヨウ化スルフェニル

Research Abstract

Novel nano-sized molecular cavities with a dendrimer-type framework were developed for modeling reaction environments in the active site of enzymes that enable the stabilization highly reactive intermediates. By utilizing the novel model compounds, several highly reactive species otherwise very unstable in artificial systems were successfully synthesized and their reactivities were elucidated. These results contribute to the experimental demonstration of the hypothetically proposed chemical processes involved in the redox regulation and signaling.

Research Products

• [Journal Article] Chloro-(η6-p-cymene)-{3-[3,5-bis(2,6dimethylphenyl)-1,2-phenylene]-1-(2,6,2"6"-tetramethyl-1,1':3',1"-terphenyl-5'-yl)imid azol-2-ylidene}-ruthenium(II) benzene disolvate (2014)
  • Author(s): Sase, S.; Ikehara, Y.; Goto, K.Domoto, Y.; Sase, S.; Goto, K.
  • Journal Title: Acta Crystallogr., Sect. E Volume: 70
  • Peer Reviewed
• [Journal Article] Efficient End-Capping Synthesis of Neutral Donor-Acceptor [2]Rotaxanes under Additive-Free and Mild Conditions (2014)
  • Author(s): Domoto, Y.; Sase, S.; Goto, K.
  • Journal Title: Chem. - Eur. J. Volume: 20 Pages: 15998-16005
  • Peer Reviewed
• [Journal Article] Transnitrosation from a stable thionitrate to an amine with concomitant formation of a sulfenic acid (2013)
  • Author(s): Goto, K.; Yoshikawa, S.; Ideue, T.; Sase, S.
  • Journal Title: J. Sulf. Chem. Volume: 34 Pages: 705-710
  • Peer Reviewed
• [Journal Article] Transnitrosation from a stable thionitrate to an amine with concomitant formation of a sulfenic acid (2013)
  • Author(s): Kei Goto, Shuhei Yoshikawa, Taku Ideue, Shohei Sase
  • Journal Title: Journal of Sulfur Chemistry Volume: 34 Issue: 6 Pages: 705-710
  • DOI: 10.1080/17415993.2013.794801
  • Peer Reviewed
• [Journal Article] Copper(I)-Dioxygen Reactivity in a Sterically Demanding Tripodal Tetradentate tren Ligand: Formation and Reactivity of a Mononuclear Copper(II) End-On Superoxo Complex (2012)
  • Author(s): Kobayashi, Y.; Ohkubo, K.; Nomura, T.; Kubo, M.; Fujieda, N.; Sugimoto, H.;Fukuzumi, S.; Goto, K.; Ogura, T.; Itoh, S.
  • Journal Title: Eur. J. Inorg. Chem. Pages: 4574-4578
  • Peer Reviewed
• [Journal Article] Iodide-Promoted Deselenylation of β -Chloro- and β -Oxyselenides to Form Alkenes and Selenenyl Iodides (2012)
  • Author(s): Sase, S.; Ebisawa, N.; Goto, K.
  • Journal Title: Chem. Lett. Volume: 41 Pages: 766-768
  • NAID: 10030946954
  • Peer Reviewed
• [Journal Article] Iodide-Promoted Deselenylation of β-Chloro- and β-Oxyselenides to Form Alkenes and Selenenyl Iodides (2012)
  • Author(s): Shohei Sase
  • Journal Title: Chemistry Letters Volume: 41 Issue: 8 Pages: 766-768
  • DOI: 10.1246/cl.2012.766
  • NAID: 10030946954
  • Peer Reviewed
• [Journal Article] Copper(I)-Dioxygen Reactivity in a Sterically Demanding Tripodal Tetradentate tren Ligand. Formation and Reactivity of a Mononuclear Copper(II) End-on Superoxo Complex (2012)
  • Author(s): Shinobu Itoh, et al.
  • Journal Title: Eur. J. Inorg. Chem. Volume: 2012 Issue: 29 Pages: 4574-4578
  • DOI: 10.1002/ejic.201200177
  • Peer Reviewed
• [Journal Article] Iodide-Promoted Deselenylation of β-Chloro- and β-Oxyselenides to Form Alkenes and Selenenyl Iodides (2012)
  • Author(s): S.Sase, K.Ebisawa, K.Goto
  • Journal Title: Chem.Lett. Volume: (In press)
  • NAID: 10030946954
  • Peer Reviewed
• [Journal Article] Syntheses of Biologically-relevant Reactive Sulfur Species by Utilizing a Primary Alkyl Steric Protection Group (2011)
  • Author(s): Sase, S.; Aoki, Y.; Abe, N.; Goto, K.
  • Journal Title: Phosphorus, Sulfur Silicon Relat. Elem. Volume: 186 Pages: 1255-1258
  • Peer Reviewed
• [Journal Article] 分子のボウルを使って生体反応活性種をモデル化する (2011)
  • Author(s): 後藤敬
  • Journal Title: 化学と教育 Volume: 59 Pages: 604-605
  • Peer Reviewed
• [Journal Article] Syntheses of Biologically-relevant Reactive Sulfur Species by Utilizing a Primary Alkyl Steric Protection Group (2011)
  • Author(s): S.Sase, Y.Aoki, N.Abe, K.Goto
  • Journal Title: Phosphorus, Sulfur Silicon Relat.Elem. Volume: 186 Issue: 5 Pages: 1255-1258
  • DOI: 10.1080/10426507.2010.538778
  • Peer Reviewed
• [Journal Article] Formation of a Unique Fluorosilene-KF Complex Bearing Bulky Substituents (2011)
  • Author(s): E.Mieda, T.Sasamori, S.Sase, K.Goto, N.Tokitoh
  • Journal Title: Chem.Lett. Volume: 40 Issue: 2 Pages: 196-197
  • DOI: 10.1246/cl.2011.196
  • NAID: 130004426144
  • Peer Reviewed
• [Journal Article] 分子キャビティを活用した含ヨウ素高反応性中間体の安定化 (2011)
  • Author(s): 後藤敬
  • Journal Title: SIS Letters Volume: 12 Pages: 604-605
  • NAID: 40022792022
  • Peer Reviewed
• [Journal Article] Synthesis of a Stable Selenoaldehyde (RCH=Se) by Self-Catalyzed Thermal Dehydration of a Primary-Alkyl-Substituted Selenenic Acid (RCH2SeOH)
  • Author(s): Sase, S.; Kakimoto, R.; Goto, K.
  • Journal Title: Angew. Chem., Int. Ed. Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Oxygen-Atom-Transfer Reactions of a Pd(II) Peroxocarbonate Complex
  • Author(s): Sase, S.; Hashimoto, M.; Goto, K.
  • Journal Title: Chem. Lett. Volume: (印刷中)
  • Peer Reviewed
• [Presentation] Organoelement Chemistry in Mechanistic Studies on Biological Reactions (2014)
  • Author(s): Kei Goto
  • Organizer: US/Japan Joint Symposium on Advanced Organo-Main Group Chemistry
  • Place of Presentation: 名古屋
  • Year and Date: 2014-03-29
• [Presentation] Bowl型骨格を有する一級アルキル置換セレネン酸から安定なセレノアルデヒドへの変換 (2014)
  • Author(s): 柿本涼,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第94春季年会
  • Place of Presentation: 名古屋
  • Year and Date: 2014-03-28
• [Presentation] Bowl型立体保護基を有するN-ヒドロキシセレネンアミドとチオールとの反応 (2014)
  • Author(s): 石原充裕,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第94春季年会
  • Place of Presentation: 名古屋
  • Year and Date: 2014-03-28
• [Presentation] 巨大分子キャビティに内包されたシステインチオールと硝酸エステルの反応 (2014)
  • Author(s): 佐野司,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第94春季年会
  • Place of Presentation: 名古屋
  • Year and Date: 2014-03-28
• [Presentation] 活性窒素種によるS-ニトロソチオールの酸化反応に関する機構的研究 (2014)
  • Author(s): 井手上拓,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第94春季年会
  • Place of Presentation: 名古屋
  • Year and Date: 2014-03-28
• [Presentation] ヨウ化セレネニルを用いたアルケンのアミノセレン化反応の開発 (2014)
  • Author(s): 高橋絵里歌,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第94春季年会
  • Place of Presentation: 名古屋
  • Year and Date: 2014-03-27
• [Presentation] キャビティ型分子骨格を活用した生体反応活性種のモデル研究 (2014)
  • Author(s): 後藤敬
  • Organizer: 第2回生物元素戦略研究会
  • Place of Presentation: 浜松
  • Year and Date: 2014-03-01
• [Presentation] Organoelement Chemistry in Mechanistic Studies on Biological Reactions (2014)
  • Author(s): Kei Goto
  • Organizer: US/Japan Joint Symposium on Advanced Organo-Main Group Chemistry
  • Place of Presentation: Nagoya (Japan)
  • Invited
• [Presentation] Modeling of Reactive Intermediates Derived from Cysteine Thiols by Utilizing Molecular Cavities (2014)
  • Author(s): Kei Goto
  • Organizer: 26th International Symposium on the Organic Chemistry of Sulfur
  • Place of Presentation: Istanbul (Turkey)
  • Invited
• [Presentation] キャビティ型置換基を活用したヨウ化セレネニルのアルケン活性化機構に関する研究 (2013)
  • Author(s): 高橋絵里歌,海老澤和明,佐瀬祥平,後藤敬
  • Organizer: 第40回有機典型元素化学討論会
  • Place of Presentation: 東大阪
  • Year and Date: 2013-12-06
• [Presentation] Bowl型立体保護基を活用した初めてのN-ヒドロキシセレネンアミドの合成 (2013)
  • Author(s): 石原充裕,佐瀬祥平,後藤敬
  • Organizer: 第40回有機典型元素化学討論会
  • Place of Presentation: 東大阪
  • Year and Date: 2013-12-06
• [Presentation] S-ニトロシステインからチオールへのニトロソ転移の反応機構の解明 (2013)
  • Author(s): 佐野司,佐瀬祥平,後藤敬
  • Organizer: 第40回有機典型元素化学討論会
  • Place of Presentation: 東大阪
  • Year and Date: 2013-12-06
• [Presentation] Bowl型立体保護基を活用したNO+によるS-ニトロソチオールの活性化機構の解明 (2013)
  • Author(s): 井手上拓,佐瀬祥平,後藤敬
  • Organizer: 第40回有機典型元素化学討論会
  • Place of Presentation: 東大阪
  • Year and Date: 2013-12-06
• [Presentation] Bowl型分子キャビティを活用したセレン含有メチオニンスルホキシド還元酵素の反応機構に関するモデル研究 (2013)
  • Author(s): 柿本涼,佐瀬祥平,後藤敬
  • Organizer: 第40回有機典型元素化学討論会
  • Place of Presentation: 東大阪
  • Year and Date: 2013-12-06
• [Presentation] Synthesis and Application of Cysteine Model Compounds Based onNano-sized Molecular Cavities (2013)
  • Author(s): Kei Goto
  • Organizer: The 16th Japan-Korea Seminar on Organic Chemistry
  • Place of Presentation: 仙台
  • Year and Date: 2013-09-27
• [Presentation] 一級アルキル置換セレネン酸の合成と安定なセレノアルデヒドへの変換 (2013)
  • Author(s): 柿本涼,佐瀬祥平,後藤敬
  • Organizer: 第24回基礎有機化学討論会
  • Place of Presentation: 東京
  • Year and Date: 2013-09-06
• [Presentation] S-ニトロソシステイン誘導体の熱分解機構に関する速度論的研究 (2013)
  • Author(s): 井手上拓,佐瀬祥平,後藤敬,Manik Ghosh,永瀬茂
  • Organizer: 第24回基礎有機化学討論会
  • Place of Presentation: 東京
  • Year and Date: 2013-09-05
• [Presentation] Modeling of Highly ReactiveIntermediates in the Reaction of Cysteine Thiols and Reactive Nitrogen Species (2013)
  • Author(s): Kei Goto
  • Organizer: 6th Heron Island Conference on Reactive Intermediates and Unusual Molecules
  • Place of Presentation: Heron Island, Great Barrier Reef, Queensland, Australia
  • Year and Date: 2013-07-11
• [Presentation] ナノサイズキャビティ型骨格を有するセレノシステインモデル化合物の合成と応用 (2013)
  • Author(s): 後藤敬,柿本涼,佐瀬祥平
  • Organizer: 第10回ホスト・ゲスト化学シンポジウム
  • Place of Presentation: 和歌山
  • Year and Date: 2013-05-25
• [Presentation] S-ニトロソシステイン誘導体の熱分解反応機構の解明 (2013)
  • Author(s): 井手上拓,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第93回春季年会
  • Place of Presentation: 草津
  • Year and Date: 2013-03-25
• [Presentation] 一級アルキル置換セレネン酸の脱水反応による安定なセレノアルデヒドの合成 (2013)
  • Author(s): 柿本涼,佐瀬祥平,後藤 敬
  • Organizer: 日本化学会第93回春季年会
  • Place of Presentation: 草津
  • Year and Date: 2013-03-25
• [Presentation] Modeling of Highly Reactive Intermediates in the Reaction of Cysteine Thiols and Reactive Nitrogen Species (2013)
  • Author(s): Kei Goto
  • Organizer: 6th Heron Island Conference on Reactive Intermediates and Unusual Molecules
  • Place of Presentation: Queensland (Australia)
  • Invited
• [Presentation] Synthesis and Application of Cysteine Model Compounds Based on Nano-sized Molecular Cavities (2013)
  • Author(s): Kei Goto
  • Organizer: The 16th Japan-Korea Seminar on Organic Chemistry
  • Place of Presentation: Sendai (Japan)
  • Invited
• [Presentation] Bowl型分子キャビティを活用したセレン含有メチオニンスルホキシド還元酵素の反応機構に関するモデ ル研究 (2013)
  • Author(s): 柿本 涼，佐瀬祥平，後藤 敬
  • Organizer: 第40回有機典型元素化学討論会
  • Place of Presentation: 東大阪
• [Presentation] 一級アルキル置換セレネン酸の脱水反応による安定なセレノアルデヒドの合成 (2013)
  • Author(s): 後藤 敬
  • Organizer: 日本化学会第93回春季年会
  • Place of Presentation: 立命館大学（草津）
• [Presentation] S-ニトロソシステイン誘導体の熱分解反応機構の解明 (2013)
  • Author(s): 後藤 敬
  • Organizer: 日本化学会第93回春季年会
  • Place of Presentation: 立命館大学（草津）
• [Presentation] S-ニトロソチオールの二分子間分解過程に関する機構的研究 (2012)
  • Author(s): 井手上拓,佐瀬祥平,後藤敬
  • Organizer: 第39回有機典型元素化学討論会
  • Place of Presentation: 盛岡
  • Year and Date: 2012-12-07
• [Presentation] Bowl型骨格をもつセレン化合物を活用したメチオニンスルホキシド還元酵素のモデル研究 (2012)
  • Author(s): 柿本涼,佐瀬祥平,後藤敬
  • Organizer: 第39回有機典型元素化学討論会
  • Place of Presentation: 盛岡
  • Year and Date: 2012-12-07
• [Presentation] 巨大分子キャビティに内包された高反応性システイン誘導体の合成 (2012)
  • Author(s): 佐野司,佐瀬祥平,後藤敬
  • Organizer: 第39回有機典型元素化学討論会
  • Place of Presentation: 盛岡
  • Year and Date: 2012-12-06
• [Presentation] Application of Cavity-shaped Molecules to Modeling ofBiologically-relevant Reactive Sulfur Species (2012)
  • Author(s): Kei Goto
  • Organizer: The 15th International Symposium "Advances in the Chemistryof Heteroorganic Compounds"
  • Place of Presentation: Lodz, Poland
  • Year and Date: 2012-11-16
• [Presentation] Modeling of Chalcogen-containing Reactive Intermediates of Biological Reactions by Utilizing Molecular Cavities (2012)
  • Author(s): Kei Goto
  • Organizer: XII International Symposium on Selected Problems of Chemistry of Acyclic and Cyclic Heteroorganic Compounds
  • Place of Presentation: Czestochowa, Poland
  • Year and Date: 2012-11-15
• [Presentation] デンドリマー型ナノサイズ分子キャビティを活用したシステインチオニトラートのモデル研究 (2012)
  • Author(s): 佐瀬祥平,佐野司,後藤敬
  • Organizer: 第23回基礎有機化学討論会
  • Place of Presentation: 京都
  • Year and Date: 2012-09-21
• [Presentation] 内部にシステインユニットを有するナノサイズ分子キャビティの開発と応用 (2012)
  • Author(s): 後藤敬,佐野司,三崎朋子,佐瀬祥平
  • Organizer: 第9回ホスト・ゲスト化学シンポジウム
  • Place of Presentation: 札幌
  • Year and Date: 2012-05-27
• [Presentation] Elucidation of the Reactivity of Biologically-relevant Reactive Sulfur Species by Utilizing Molecular Cavities (2012)
  • Author(s): Kei Goto
  • Organizer: The 10th International Conference on Heteroatom Chemistry
  • Place of Presentation: 宇治
  • Year and Date: 2012-05-25
• [Presentation] Investigation on Disulfide Formation from S-Nitrosothiols by Taking Advantage of a Bowl-shaped Substituent (2012)
  • Author(s): Taku Ideue, Shohei Sase, and Kei Goto
  • Organizer: The 10th International Conference on Heteroatom Chemistry
  • Place of Presentation: 宇治
  • Year and Date: 2012-05-22
• [Presentation] Synthesis and Reactivity of a Cysteine Thionitrate Derivative by Taking Advantage of a Bowl-shaped Molecular Cavity (2012)
  • Author(s): Tsukasa Sano, Shohei Sase, and Kei Goto
  • Organizer: The 10th International Conference on Heteroatom Chemistry
  • Place of Presentation: 宇治
  • Year and Date: 2012-05-22
• [Presentation] Modeling of the Key Reduction Step of Selenocysteine-containing Methionine Sulfoxide Reductase (2012)
  • Author(s): Ryo Kakimoto, Shohei Sase, and Kei Goto
  • Organizer: The 10th International Conference on Heteroatom Chemistry
  • Place of Presentation: 宇治
  • Year and Date: 2012-05-22
• [Presentation] デンドリマー型分子キャビティを活用したS-ニトロソおよびS-ニトロシステイン誘導体の合成と反応 (2012)
  • Author(s): 佐野司,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第92回春季年会
  • Place of Presentation: 横浜
  • Year and Date: 2012-03-27
• [Presentation] Bowl型分子キャビティを活用したS-ニトロソチオールの二分子間分解反応の解明 (2012)
  • Author(s): 井手上拓,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第92回春季年会
  • Place of Presentation: 横浜
  • Year and Date: 2012-03-25
• [Presentation] Bowl型分子キャビティを活用したセレノールによるスルホキシド還元過程の解明 (2012)
  • Author(s): 柿本涼,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第92回春季年会
  • Place of Presentation: 横浜
  • Year and Date: 2012-03-25
• [Presentation] ヨウ化セレネニルの生成を鍵とした新規合成反応の開発 (2012)
  • Author(s): 海老澤和明,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第92回春季年会
  • Place of Presentation: 横浜
  • Year and Date: 2012-03-25
• [Presentation] HNO供与体としてのN-ヒドロキシスルフェンアミドの反応性 (2012)
  • Author(s): 石原充裕,佐瀬祥平,後藤敬
  • Organizer: 日本化学会第92回春季年会
  • Place of Presentation: 横浜
  • Year and Date: 2012-03-25
• [Presentation] Elucidation of the Reactivity of Biologically-relevant Reactive Sulfur Species by Utilizing Molecular Cavities (2012)
  • Author(s): Kei Goto
  • Organizer: The 10th International Conference on Heteroatom Chemistry
  • Place of Presentation: 京都大学（宇治）
  • Invited
• [Presentation] Modeling of the Key Reduction Step of Selenocysteine-containing Methionine Sulfoxide Reductase (2012)
  • Author(s): Kei Goto
  • Organizer: The 10th International Conference on Heteroatom Chemistry
  • Place of Presentation: 京都大学（宇治）
• [Presentation] Investigation on Disulfide Formation from S-Nitrosothiols by Taking Advantage of a Bowl-shaped Substituent (2012)
  • Author(s): Kei Goto
  • Organizer: The 10th International Conference on Heteroatom Chemistry
  • Place of Presentation: 京都大学（宇治）
• [Presentation] Synthesis and Reactivity of a Cysteine Thionitrate Derivative by Taking Advantage of a Bowl-shaped Molecular Cavity (2012)
  • Author(s): Kei Goto
  • Organizer: The 10th International Conference on Heteroatom Chemistry
  • Place of Presentation: 京都大学（宇治）
• [Presentation] 内部にシステインユニットを有するナノサイズ分子キャビティの開発と応用 (2012)
  • Author(s): 後藤 敬
  • Organizer: 第9回ホスト・ゲスト化学シンポジウム
  • Place of Presentation: 北海道大学（札幌）
• [Presentation] デンドリマー型ナノサイズ分子キャビティを活用したシステインチオニトラートのモデル研究 (2012)
  • Author(s): 後藤 敬
  • Organizer: 第23回基礎有機化学討論会
  • Place of Presentation: 京都テルサ（京都）
• [Presentation] 巨大分子キャビティに内包された高反応性システイン誘導体の合成 (2012)
  • Author(s): 後藤 敬
  • Organizer: 第39回有機典型元素化学討論会
  • Place of Presentation: いわて県民情報交流センター（盛岡）
• [Presentation] Bowl型骨格をもつセレン化合物を活用したメチオニンスルホキシド還元酵素のモデル研究 (2012)
  • Author(s): 後藤 敬
  • Organizer: 第39回有機典型元素化学討論会
  • Place of Presentation: いわて県民情報交流センター（盛岡）
• [Presentation] Modeling of Reactive Species Derived from Cysteine and Selenocysteine Residues by Utilizing aPhenylene-based Molecular Cavity (2011)
  • Author(s): Kei Goto
  • Organizer: 1st International Symposium on Creation of Functional Materials
  • Place of Presentation: つくば
  • Year and Date: 2011-12-17
• [Presentation] Modeling of Reactive Species Derived from Cysteine and Selenocysteine Residues by Utilizing a Phenylene-based Molecular Cavity (2011)
  • Author(s): K.Goto
  • Organizer: 1st International Sympojium on Creation of Functional Materials
  • Place of Presentation: つくば(招待講演)
  • Year and Date: 2011-12-17
• [Presentation] Bowl型分子キャビティを活用したN-ヒトロキシスルフェンアミドの反応性に関するモデル研究 (2011)
  • Author(s): 石原充裕,吉川修平,佐瀬祥平,後藤敬
  • Organizer: 第38回有機典型元素化学討論会
  • Place of Presentation: 金沢
  • Year and Date: 2011-12-09
• [Presentation] Bowl型分子キャヒティを活用したN-ヒトロキシスルフェンアミトの反応性に関するモテル研究 (2011)
  • Author(s): 石原充裕, 吉川修平, 佐瀬祥平, 後藤敬
  • Organizer: 第38回有機典型元素化学討論会
  • Place of Presentation: 金沢
  • Year and Date: 2011-12-09
• [Presentation] 分子キャビティを活用した含高周期典型元素活性種の反応性制御 (2011)
  • Author(s): 後藤敬
  • Organizer: 第38回有機典型元素化学討論会
  • Place of Presentation: 金沢
  • Year and Date: 2011-12-08
• [Presentation] 分子キャビティを活用した含高周期典型元素活性種の反応性制御 (2011)
  • Author(s): 後藤敬
  • Organizer: 第38回有機典型元素化学討論会
  • Place of Presentation: 金沢(招待講演)
  • Year and Date: 2011-12-08
• [Presentation] Modeling of Biologically-relevant Reactive Sulfur Species by Utilizing Molecular Cavities (2011)
  • Author(s): Kei Goto, Noriaki Abe, Michihiro Ishihara, and Shohei Sase
  • Organizer: The 15th Japan-Korea Seminar on Organic Chemistry
  • Place of Presentation: Gyeongju, Korea
  • Year and Date: 2011-10-02
• [Presentation] Modeling of Biologically-relevant Reactive Sulfur Species by Utilizing Molecular Cavities (2011)
  • Author(s): K.Goto, N.Abe, M.Ishihara, S.Sase
  • Organizer: The 15th Japan-Korea Seminar on Organic Chemistry
  • Place of Presentation: Gyeongju, Korea(招待講演)
  • Year and Date: 2011-10-02
• [Presentation] デンドリマー型分子キャビティを活用した安定なシステインヨウ化スルフェニルの合成 (2011)
  • Author(s): 佐野司,三﨑朋子,佐瀬祥平,後藤敬
  • Organizer: 第5回バイオ関連化学シンポジウム
  • Place of Presentation: つくば
  • Year and Date: 2011-09-13
• [Presentation] Modeling of Chalcogen-containing Reactive Intermediates of Biological Reactions by Utilizing Molecular Cavities
  • Author(s): Kei Goto
  • Organizer: XII International Symposium on Selected Problems of Chemistry of Acyclic and Cyclic Heteroorganic Compounds
  • Place of Presentation: Czestochowa(Poland)
  • Invited
• [Presentation] Application of Cavity-shaped Molecules to Modeling of Biologically-relevant Reactive Sulfur Species
  • Author(s): Kei Goto
  • Organizer: The 15th International Symposium “Advances in the Chemistry of Heteroorganic Compounds”
  • Place of Presentation: Lodz(Poland)
  • Invited
• [Book] Synergy in Supramolecular Chemistry (2014)
  • Author(s): Kei Goto et al.
  • Publisher: CRC Press/Auerbach/Chapman & Hall/Productivity Press