Research on Full-protocol Disease Marker Screening System using Integrated Lab-on-a-CD for Immunoassay

• Project/Area Number: 23350035
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Analytical chemistry
• Research Institution: University of Hyogo
• Principal Investigator: UTSUMI Yuichi 兵庫県立大学, 高度産業科学技術研究所, 教授 (80326298)
• Co-Investigator(Kenkyū-buntansha): TAKEO Masahiro 兵庫県立大学, 大学院・工学研究科, 准教授 (40236443) ; YUSA Shinichi 兵庫県立大学, 大学院・工学研究科, 准教授 (00301432) ; UKITA Yoshiaki 北陸先端科学技術大学院大学, マテリアルサイエンス研究科, 助教 (40578100) ; KATAOKA Masatoshi) 産業技術総合研究所, 健康工学研究部門, グループ長 (20224438)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000); Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2011: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
• Keywords: チップ分析 / 生体分析 / 免疫反応 / バイオリアクター / ELISA / マイクロ化学システム / Lab-on-a-chip / Lab-on–a-chip

Research Abstract

This paper reports a new type of lab-on-a-CD device with three-dimensional microchannel networks and vertical capillary bundle structure. The device consist of the multiple lab-on-a-CD chips with conventional planer microchannels and vertical microchannels which constructed on the disks made of poly-dimethylsiloxane (PDMS) and poly-methylmethacrilrate (PMMA). The PMMA layer with vertical channel were fabricated by deep X-ray lithography using synchrotron radiation. We designed and fabricated the chips for aim of taking enzyme-linked immunosorbent assay(ELISA). Three-dimensional liquid transportation through Lab-on-a-CD structure is suggested by computational fluid dynamics and it is successfully demonstrated chips. Detection of immunogroblin G(IgG) from mouse is successfully demonstrated in the three-dimensional devices and it is notable that the result suggests quite high-sensitive implying detection limit down to 1ng/mL by primitive result.

Research Products

• [Journal Article] Optofluidic Devices with Surface-Enhanced Raman Scattering Active Three- Dimensional Gold Nanostructure (2013)
  • Author(s): Ryo Takahashi, Takao Fukuoka, Yuichi Utsumi, Akinobu Yamaguchi
  • Journal Title: Japanese Journal of Applied Physics Volume: 52
  • Peer Reviewed
• [Journal Article] Application of photo-etching of polytetrafluoroethylene induced by high energy synchrotron radiation to LIGA (2013)
  • Author(s): Hideki Kido, Tomoyuki Kuroki, Masaaki Okubo, Yuichi Utsumi
  • Journal Title: Microsystem Technologies Volume: 19, 3 Pages: 301-307
  • Peer Reviewed
• [Journal Article] Optofluidic Devices with Surface-Enhanced Raman Scattering Active Three- Dimensional Gold Nanostructure (2013)
  • Author(s): Ryo Takahashi, Takao Fukuoka, Yuichi Utsumi, and Akinobu Yamaguchi
  • Journal Title: Japanese Journal of Applied Physics Volume: 52 Issue: 6S Pages: 365-371
  • DOI: 10.7567/jjap.52.06gk12
  • Peer Reviewed
• [Journal Article] Stacked centrifugal microfluidic device with three-dimensional microchannel networks and multifunctional capillary bundle structures for immunoassay (2012)
  • Author(s): Yoshiaki Ukita, Saki Kondo, Tsukasa Azeta, Masaki Ishizawa, Chiwa Kataoka, Masahiro Takeo, Yuichi Utsumi
  • Journal Title: Sensors and Actuators B : Chemical Volume: 166-167 Pages: 898-906
  • Peer Reviewed
• [Journal Article] Proposal of High-Integrated Three-Dimensional Microfluidic by Using Centrifugal Force for Enzyme Linked Immunosorbent Assay (2012)
  • Author(s): Tsukasa Azeta, Yuichi Utsumi
  • Journal Title: Journal of Japan Institute of Electronics packaging Volume: 15, 1 Pages: 38-41
  • NAID: 10030040704
  • Peer Reviewed
• [Journal Article] Proposal of High-Integrated Three-Dimensional Microfluidic by Using Centrifusal Force for Enzyme Linked Immunosorbent Assay (2012)
  • Author(s): Tsukasa Azeta, Yuichi Utsumi
  • Journal Title: Journal of Japan Institute of Electronics packaging Volume: 15 Pages: 38-41
  • Peer Reviewed
• [Journal Article] A Novel Micromixer with Three-Dimensionally Cross-Linked Capillary Array Structure Fabricated by Deep X-ray Lithography (2011)
  • Author(s): Saki Kondo, Yoshiaki Ukita, Kuniyo Fujiwara, Yuichi Utsumi
  • Journal Title: Electrical Engineering in Japan Volume: 177, 1 Pages: 26-31
  • NAID: 10023999770
  • Peer Reviewed
• [Presentation] Novel Pressure-Controlling Valve of Centrifugal Microfluidics (2014)
  • Author(s): Masaki Ishizawa, Yasuto Arisue, Ikuo Okada, Akinobu Yamaguchi, Yuichi Utsumi
  • Organizer: PITTCON2014
  • Place of Presentation: Chicago, USA
• [Presentation] Novel Pressure-Controlling Valve of Centrifugal Microfluidics (2014)
  • Author(s): M. Ishizawa, Y. Arisue, I. Okada, A. Yamaguchi, and Y. Utsumi
  • Organizer: PITTCON2014
  • Place of Presentation: McCormick Place, Chicago, USA
• [Presentation] Proposal of a Lab-on-a-CD for immunoassay using nonmechanical pump and valves (2014)
  • Author(s): Yasuto Arisue, Masaki Ishizawa, Akinobu Yamaguchi, Yuichi Utsumi
  • Organizer: PITTCON2014
  • Place of Presentation: McCormick Place, Chicago, USA
• [Presentation] Blood separation lab-on-a-CD with controlled surface (2013)
  • Author(s): Hiroki Nose, Masaki Ishizawa, Takeshi Kunisada, Kazuhisa Kuroda, Akinobu Yamaguchi, Yuichi Utsumi
  • Organizer: 7th International Conference on Molecular Electronics and Bioelectronics (M&BE7)
  • Place of Presentation: 福岡国際会議場, Fukuoka, Japan
• [Presentation] Development of Automatic ELISA Analytical System for a Trace Amount of Nonylphenol Using a Novel Antigen-Bound Microfilter (2013)
  • Author(s): M. Takeo, I. Kawaji, A. Nakasuji, T. Tone, Y. Ukita, D. Kato, S. Negoro, S. Yusa, M. Katayama and Y. Utsumi
  • Organizer: 10th International Workshop on High Aspect Ratio Micro and Nano System Technology
  • Place of Presentation: SEMINARIS CAMPUSHOTEL BERLIN, Berlin, Germany
• [Presentation] Fabrication of amino acid analysis chip using SR direct dry etching of PTFE (2013)
  • Author(s): H. Kido, I. Okada, H. Mita, A. Yamaguchi, Y. Utsumi
  • Organizer: 10th International Workshop on High Aspect Ratio Micro and Nano System Technology
  • Place of Presentation: SEMINARIS CAMPUSHOTEL BERLIN, Berlin, Germany
• [Presentation] Blood separation chip for automated biological analysis (2013)
  • Author(s): T. Kunisada, H. Nose, M. Ishizawa, K. Kuroda, I. Okada, A. Yamaguchi and Y. Utsumi
  • Organizer: 10th International Workshop on High Aspect Ratio Micro and Nano System Technology
  • Place of Presentation: SEMINARIS CAMPUSHOTEL BERLIN, Berlin, Germany
• [Presentation] Development of a Portable Fluidic and Detection System for ELISA in a 3-Dimensional Microreactor (2013)
  • Author(s): M. Takeo, S. Nii, D. Kato, S. Negoro, S. Yusa, T. Saiki,Y. Takizawa, Y. Utsumi
  • Organizer: Proc. of 39th International Conference on Micro and Nano Engineering (MNE2013)
  • Place of Presentation: Imperial College London, London, UK
• [Presentation] Centrifugal Microfluidic Chip for Blood Separation (2013)
  • Author(s): M. Ishizawa, T.Kunisada, K.Kuroda, C.Kataoka , A.Yamaguchi and Y.Utsumi
  • Organizer: Proc. of 2013 International Microprocesses and Nanotechnology Conference (MNC2013)
  • Place of Presentation: Royton Sapporo Hakkaido, Japan
• [Presentation] Proposal of a Novel Internally-Triggered Automatic Flow Sequencing on Centrifugal Microfluidics (2013)
  • Author(s): M. Ishizawa, H. Nose, Y. Ukita, and Y. Utsumi
  • Organizer: International Conference on Electronics Packaging（ICEP2013）
  • Place of Presentation: Osaka International Convention Center, Osaka, Japan
• [Presentation] Blood separation lab-on-a-CD with controlled surface (2013)
  • Author(s): Hiroki Nose, Masaki Ishizawa, Takeshi Kunisada, Kazuhisa Kuroda, Akinobu Yamaguchi, Yuichi Utsumi
  • Organizer: 7th International Conference on Molecular Electronics and Bioelectronics (M&BE7)
  • Place of Presentation: Fukuoka International Congress Center, Fukuoka
• [Presentation] Three-Dimensional Magneto Impedance Sensor using a Multi Layers Electroplating technique (2013)
  • Author(s): Yuji Yoritama, S. Yamamoto, T. Uchiyama , Akinobu Yamaguchi, Yuichi Utsumi
  • Organizer: 7th International Conference on Molecular Electronics and Bioelectronics (M&BE7)
  • Place of Presentation: Fukuoka International Congress Center, Fukuoka
• [Presentation] Contamination-Free Internally-Triggered Automatic Flow Sequencing for Microfluidics (2012)
  • Author(s): Masaki Ishizawa, Yuichi Utsumi
  • Organizer: 38th International Conference on Micro and Nano Engineering (MNE2012)
  • Place of Presentation: Toulouse, France
• [Presentation] Visualization of Biological Fluid Behaviour on Spinning Centrifugal Microfluidics using Coaxial Micro-Stroboscope (2012)
  • Author(s): Yoshiaki Ukita, Takayuki Oguro, Masaki Ishizawa, Hiroki Nose, Yuichi Utsumi, Yuzuru Takamura
  • Organizer: 38th International Conference on Micro and Nano Engineering (MNE2012)
  • Place of Presentation: Toulouse, France
• [Presentation] Three-Dimensional Lab-on-a-CD with Enzyme-Linked Immunosorbent Assay (2012)
  • Author(s): Masaki Ishizawa, Tsukasa Azeta, Hiroki Nose, Yoshiaki Ukita, Yuichi Utsumi
  • Organizer: Nano/Micro Engineered and Molecular Systems (IEEE-NEMS 2012)
  • Place of Presentation: 京都大学, Kyoto, Japan
• [Presentation] Blood separation chip for automated biological analysis (2012)
  • Author(s): Hiroki Nose, Masaki Ishizawa, Kazuhisa Kuroda, Takeshi Kunisada, Masatoshi Kataoka, Yuichi Utsumi
  • Organizer: RSC(Royal Society of Chemistry) Tokyo International Conference
  • Place of Presentation: Makuhari Messe, Chiba
• [Presentation] ERS Active Self-assembled Nanostructures toward Higher Dimension III: Sterically-bulky Self Assembles Array (2012)
  • Author(s): Ryo Takahashi, Takao Fukuoka, Yuichi Utsumi
  • Organizer: RSC(Royal Society of Chemistry) Tokyo International Conference
  • Place of Presentation: Makuhari Messe, Chiba
• [Presentation] SERS Active Self-assembled Nanostructures toward Higher Dimension II : Physically Self-assembled Nanoparticles Array (2012)
  • Author(s): Takao Fukuoka, Ryo Takahashi, Yuichi Utsumi, Motofumi Suzuki
  • Organizer: RSC(Royal Society of Chemistry) Tokyo International Conference
  • Place of Presentation: Makuhari Messe, Chiba
• [Presentation] Three Dimensional Gold Nanostructure for Plasmonic Sensing (2012)
  • Author(s): Ryo Takahashi, Takao Fukuoka, Yuichi Utsumi
  • Organizer: Gold Science Technology and its Applications, the 6th International Conference
  • Place of Presentation: Keio Plaza Hotel Tokyo, Tokyo
• [Presentation] Fabrication of Integrated Magneto Impedance Sensor for Medical Monitoring (2012)
  • Author(s): Yuji Yoritama, T. Uchiyama , Akinobu Yamaguchi, Yuichi Utsumi
  • Organizer: 38th International Conference on Micro and Nano Engineering (MNE2012)
  • Place of Presentation: Pierre Baudis Congress Centre, Toulouse, France
• [Presentation] Contamination-Free Internally-Triggered Automatic Flow Sequencing for Microfluidics (2012)
  • Author(s): Masaki Ishizawa, Yuichi Utsumi
  • Organizer: 38th International Conference on Micro and Nano Engineering (MNE2012)
  • Place of Presentation: Pierre Baudis Congress Centre, Toulouse, France
• [Presentation] Fabrication of fluorocarbon resin micro fluidic chip for processing of amino acid derivatization (2012)
  • Author(s): Hideki Kido, Yuichi Utsumi, Toshihiko Asami, Hajime Mita
  • Organizer: 38th International Conference on Micro and Nano Engineering (MNE2012)
  • Place of Presentation: Pierre Baudis Congress Centre, Toulouse, France
• [Presentation] SERS Active Three Dimensional Gold Nanostructure Fabrication for Optofluidic Device (2012)
  • Author(s): Ryo Takahashi, Takao Fukuoka, Yuichi Utsumi
  • Organizer: 38th International Conference on Micro and Nano Engineering (MNE2012)
  • Place of Presentation: Pierre Baudis Congress Centre, Toulouse, France
• [Presentation] Single Molecule Detection Using Sterically-bulky Self Assembles of Gold Nanoparticles (2012)
  • Author(s): Ryo Takahashi, Mitsuhiro Yoshida, Yuichi Utsumi
  • Organizer: 38th International Conference on Micro and Nano Engineering (MNE2012)
  • Place of Presentation: Pierre Baudis Congress Centre, Toulouse, France
• [Presentation] Direction Control of Powder Transport on Solid Substrate by Drive Frequency of Surface Acoustic Wave Actuator (2012)
  • Author(s): Tsunemasa Saiki, Yasuto Arisue, Kei Kuramoto, Hiroo Shizuka, Masahiro Takeo, Kazusuke Maenaka, Yuichi Utsumi
  • Organizer: 38th International Conference on Micro and Nano Engineering (MNE2012)
  • Place of Presentation: Pierre Baudis Congress Centre, Toulouse, France
• [Presentation] Visualization of Biological Fluid Behaviour on Spinning Centrifugal Microfluidics using Coaxial Micro-Stroboscope (2012)
  • Author(s): Yoshiaki Ukita, Takayuki Oguro, Masaki Ishizawa, Hiroki Nose, Yuichi Utsumi, Yuzuru Takamura
  • Organizer: 38th International Conference on Micro and Nano Engineering (MNE2012)
  • Place of Presentation: Pierre Baudis Congress Centre, Toulouse, France
• [Presentation] Automatic ELISA Analytical System for a Trace Amount of Environmental Chemicals Using A 3-Dimensional Microreactor with a Novel Antigen-Bound Microfilter (2012)
  • Author(s): Masahiro Takeo, Isao Kawaji, Akihiro Nakasuji, Takaaki Tone, Yoshiaki Ukita, Dai-ichiro Kato, Seiji Negoro, Shinichi Yusa, Makoto Katayama, Yuichi Utsumi
  • Organizer: 16th International Conference on Miniaturized Systems for Chemistry and Life Science (μTAS)
  • Place of Presentation: Okinawa Convention Center, Okinawa
• [Presentation] Internally Triggerd Multistep Flow Sequencers Using Clepsydra (2012)
  • Author(s): Yoshiaki Ukita, Masaki Ishizawa, Yuzuru Takamura, Yuichi Utsumi
  • Organizer: 16th International Conference on Miniaturized Systems for Chemistry and Life Science (μTAS)
  • Place of Presentation: Okinawa Convention Center, Okinawa
• [Presentation] Preparation of Freeze-Dried Porous Media in a Microchannel: A New Platform for Enzymatic Reactions (2012)
  • Author(s): Kyuya Nakagawa, Akihiro Tamura, Yuki Goto, Masahiro Takeo, Yuichi Utsumi
  • Organizer: 16th International Conference on Miniaturized Systems for Chemistry and Life Science (μTAS)
  • Place of Presentation: Okinawa Convention Center, Okinawa
• [Presentation] Fabrication of PTFE micro fluidic chip for processing of amino acid derivatization (2012)
  • Author(s): Hideki Kido, Yuichi Utsumi, Toshihiko Asami, Hajime Mita
  • Organizer: 25th International Microprocesses and Nanotechnology Conference (MNC2012)
  • Place of Presentation: Kobe Meriken Park Oriental Hotel, Hyogo
• [Presentation] Proposal of Particle Size Sorting Method by Surface Acoustic Wave (2012)
  • Author(s): Yasuto Arisue, Tsunemasa Saiki, Kei Kuramoto, Yutaka Hata, Hiroo Shizuka, Kazusuke Maenaka, Yuichi Utsumi
  • Organizer: 25th International Microprocesses and Nanotechnology Conference (MNC2012)
  • Place of Presentation: Kobe Meriken Park Oriental Hotel, Hyogo
• [Presentation] Clepsydra-based Autonomous Flow Sequencer with Liquid Trap Reservoir (2012)
  • Author(s): Masaki Ishizawa, Yuichi Utsumi
  • Organizer: 25th International Microprocesses and Nanotechnology Conference (MNC2012)
  • Place of Presentation: Kobe Meriken Park Oriental Hotel, Hyogo
• [Presentation] Optofluidic Device with SERS Active Three Dimensional Gold Nanostructure (2012)
  • Author(s): Ryo Takahashi, Takao Fukuoka, Yuichi Utsumi
  • Organizer: 25th International Microprocesses and Nanotechnology Conference (MNC2012)
  • Place of Presentation: Kobe Meriken Park Oriental Hotel, Hyogo
• [Presentation] Gold nanoparticles self-assembly assisted with imprinted HSQ pattern for SERS measurement (2012)
  • Author(s): Y. Kang, R. Takahashi, T. Fukuoka, Y. Utsumi, M. Okada, Y. Haruyama, S. Matsui
  • Organizer: 25th International Microprocesses and Nanotechnology Conference (MNC2012)
  • Place of Presentation: Kobe Meriken Park Oriental Hotel, Hyogo
• [Presentation] A Chip-Size Structure for Continuous Microwave Irradiation by Post-Wall Waveguide (2012)
  • Author(s): Mitsuyoshi Kishihara, M. Yamashima, Yuichi Utsumi
  • Organizer: Proc. of 2012 Asia-Pacific Microwave Conference
  • Place of Presentation: Ambassador Hotel, Kaohsiung, Taiwan
• [Presentation] Self-assembly of gold nanoparticles using imprinted HSQ pattern for SERS measuremen (2012)
  • Author(s): Y. Kang, R. Takahashi, T. Fukuoka, Y. Utsumi, Y. Haruyama, and S. Matsui
  • Organizer: 11th International Conference on Nanoimprint and Nanoprint Technology (NNT12)
  • Place of Presentation: Silverado Resort and Spa, Napa, USA
• [Presentation] Development of 3D Microfabrication using Synchrotron Radiation and Its Applications (2012)
  • Author(s): Yuichi Utsumi
  • Organizer: 5th SERC School on "New Development in Microfabrication with focus on synchrotron based deep x-ray lithography"
  • Place of Presentation: Raja Ramanna Centre for Advanced Technology, Indore, India
  • Invited
• [Presentation] Development of Bio-Microsystems and Sensors using nano/micro-structures (2012)
  • Author(s): Yuichi Utsumi
  • Organizer: Short term school on "Micromanufacturing"
  • Place of Presentation: Indian Institute of Technology Kanpur, Kanpur, India
  • Invited
• [Presentation] Three-dimensional Micro Fluidics Device Using Centrifugal Force (2011)
  • Author(s): Tsukasa Azeta, Hiroki Nose, Saki Kondo, Yuichi Utsumi
  • Organizer: International Conference on Electronics Packaging (ICEP2011)
  • Place of Presentation: 奈良県新公会堂(奈良県)
  • Year and Date: 2011-04-14
• [Presentation] High-sensitive Detection of Polychlorinated Biphenyl on Three-dimensional Lab-on-a-CD (2011)
  • Author(s): Tsukasa Azeta, Yoshiaki Ukita, Yoshito Hirose, Saki Kondo, Yuichi Utsumi
  • Organizer: International Conference on Electronics Packaging (ICEP2011)
  • Place of Presentation: 奈良県新公会堂(奈良県)
  • Year and Date: 2011-04-14
• [Presentation] High-sensitive Enzyme-linked Immunosorbent Assey in Three-dimensional Lab-on-a-CD (2011)
  • Author(s): Hiroki Nose, Tsukasa Azeta, Yoshiaki Ukita, Saki Kondo, Chiwa Kataoka, Yuichi Utsumi
  • Organizer: International Conference on Electronics Packaging (ICEP2011)
  • Place of Presentation: 奈良県新公会堂(奈良県)
  • Year and Date: 2011-04-14
• [Presentation] Multi Stacked Centrifugal Microfluidics for Enzyme-linked Immunosorbent Assay (2011)
  • Author(s): Masaki Ishizawa, Tsukasa Azeta, Hiroki Nose, Yoshiaki Ukita, Masahiro Takeo, Kyuya Nakagawa, Shinichi Yusa, Yuichi Utsumi
  • Organizer: 37th International Confedence on Micro and Nano Engineering (MNE2011)
  • Place of Presentation: Berlin, Germany
• [Presentation] Proposal of Three-dimensional Microfluidics Device For Immunoassay Using Centrifugal Force (2011)
  • Author(s): Tsukasa Azeta, Yoshiaki Ukita, Yuichi Utsumi
  • Organizer: 9th International Workshop on High Aspect Ratio Micro Structure Technology (HARMST2011)
  • Place of Presentation: Hsin Chu, Taiwan
• [Presentation] Three-Dimensional Lab-on-a-CD with Enzyme-Linked Immunosorbent Assay (2011)
  • Author(s): Tsukasa Azeta, Yoshiaki Ukita, Masahiro Takeo, Kyuya. Nakagawa, Shinichi Yusa, Yuichi Utsumi
  • Organizer: 9th International Workshop on High Aspect Ratio Micro Structure Technology (HARMST2011)
  • Place of Presentation: Hsin Chu, Taiwan
• [Presentation] Environmental Analysis using Stacked Centrifugal Microfluidicsy (2011)
  • Author(s): Yoshiaki Ukita, Tsukasa Azeta, Saki Kondo, Chiwa Kataoka, Shinichi Yusa, Masahiro Takeo, Yuichi Utsumi
  • Organizer: 9th International Workshop on High Aspect Ratio Micro Structure Technology (HARMST2011)
  • Place of Presentation: Hsin Chu, Taiwan
• [Presentation] Proposal of Three-dimensional Microfluidics Device For Immunoassay Using Centrifugal Force (2011)
  • Author(s): Tsukasa Azeta, Yoshiaki Ukita, Yuichi Utsumi
  • Organizer: The 9^<th> International Workshop on High Aspect Ratio Micro Structure Technology (HARMST2011)
  • Place of Presentation: Hsin Chu, Taiwan
• [Presentation] Three-Dimensional Lab-on-a-CD with Enzyme-Linked Immunosorbent Assay (2011)
  • Author(s): Tsukasa Azeta, Yoshiaki Ukita, Masahiro Takeo, Kyuya. Nakagawa, Shinichi Yusa, Yuichi Utsumi
  • Organizer: The 9^<th> International Workshop on High Aspect Ratio Micro Structure Technology (HARMST2011)
  • Place of Presentation: Hsin Chu, Taiwan
• [Presentation] Propose a blood separation chip for 3D lab-on-a-CD (2011)
  • Author(s): Tsukasa Azeta, Hiroki Nose, Masatoshi Kataoka, Yuichi Utsumi
  • Organizer: The 9^<th> International Workshop on High Aspect Ratio Micro Structure Technology (HARMST2011)
  • Place of Presentation: Hsin Chu, Taiwan
• [Presentation] Environmental Analysis using Stacked Centrifugal Microfluidics (2011)
  • Author(s): Yoshiaki Ukita, Tsukasa Azeta, Saki Kondo, Chiwa Kataoka, Shinichi Yusa, Masahiro Takeo, Yuichi Utsumi
  • Organizer: The 9^<th> International Workshop on High Aspect Ratio Micro Structure Technology (HARMST2011)
  • Place of Presentation: Hsin Chu, Taiwan
• [Presentation] Proposal a Preparation Chip for 3D Lab-no-a-CD (2011)
  • Author(s): Hiroki Nose, Tsukasa Azeta, Masatoshi Kataoka, Masahiro Takeo, Kyuya Nakagawa, Shinichi Yusa, Yuichi Utsumi
  • Organizer: 37^<th> International Confedence on Micro and Nano Engineering (MNE2011)
  • Place of Presentation: Berlin, Germany
• [Presentation] A Novel Flow Sequencing Method on Centrifugal Microfluidic Device using "Liquid Clock (2011)
  • Author(s): Yoshiaki Ukita, Y.Takamura, Yuichi Utsumi
  • Organizer: 25^<th> International Microprocesses and Nanotechnology Conference (MNC2011)
  • Place of Presentation: 京都ANAホテル(京都府)