• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Developement of New Synthetic Methods for Nitrogen-containing Compounds

Research Project

Project/Area Number 23350041
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Synthetic chemistry
Research InstitutionKyoto University

Principal Investigator

MURAKAMI Masahiro  京都大学, 工学(系)研究科(研究院), 教授 (20174279)

Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2013: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2012: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2011: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Keywords有機合成 / 反応開発 / 遷移金属触媒 / 含窒素化合物 / 合成化学 / 有機化学 / ヘテロ環 / 炭素-水素結合 / 含窒素複素環 / トリアゾール / 脱窒素 / 遷移金属 / メタラサイクル
Research Abstract

In this project, we have embarked on the development of new synthetic methods for nitrogen-containing compounds by exploiting transition metal catalysis. For example, we have developed (1) methods to incorporate nitrogen and oxygen, carbon, sulfur into unsaturated molecules, (2) new methods to generate reactive metallacycles and their synthetic applications, (3) new methods to synthesize nitrogen heterocycles via cleavage of a carbon–hydrogen bond. These new methods offer efficient ways to nitrogen-containing compounds that are otherwise difficult to access.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (37 results)

All 2014 2013 2012 2011 Other

All Journal Article (21 results) (of which Peer Reviewed: 21 results,  Open Access: 1 results) Presentation (14 results) (of which Invited: 1 results) Remarks (2 results)

  • [Journal Article] Intramolecular Dearomatizing [3 + 2] Annulation of α-Imino Carbenoids with Aryl Rings Furnishing 3,4-Fused Indole Skeletons2014

    • Author(s)
      Tomoya Miura *, Yuuta Funakoshi , and Masahiro Murakami *
    • Journal Title

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

      Volume: 136 Issue: 6 Pages: 2272-2275

    • DOI

      10.1021/ja412663a

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] sp3-sp2 vs sp3-sp3 C-C Site-Selectivity in Rh-Catalyzed Ring Opening of Benzocyclobutenol: A DFT Study2014

    • Author(s)
      Lina Ding, Naoki Ishida, Masahiro Murakami, and Keiji Morokuma
    • Journal Title

      Journal of the American Chemical Society

      Volume: 136 Issue: 1 Pages: 169-178

    • DOI

      10.1021/ja407422q

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stereospecific ring expansion from orthocyclophanes with central chirality to metacyclophanes with planar chirality2014

    • Author(s)
      Naoki Ishida, Shota Sawano, and Masahiro Murakami
    • Journal Title

      Nature Communnications

      Volume: 5 Issue: 1 Pages: 3111-3111

    • DOI

      10.1038/ncomms4111

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cleavage of C-C and C-Si σ-Bonds and Their Exchange2014

    • Author(s)
      Naoki Ishida, Wataru Ikemoto, and Masahiro Murakami
    • Journal Title

      Journal of the American Chemical Society

      Volume: 136 Issue: 16 Pages: 5912-5915

    • DOI

      10.1021/ja502601g

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective Synthesis of anti Homoallylic Alcohols from Terminal Alkynes and Aldehydes Based on Concomitant Use of a Cationic Iridium Complex and a Chiral Phosphoric Acid2013

    • Author(s)
      Tomoya Miura, Yui Nishida, Masao Morimoto, and Masahiro Murakami
    • Journal Title

      Journal of the American Chemical Society

      Volume: 135 Issue: 31 Pages: 11497-11500

    • DOI

      10.1021/ja405790t

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pyridine-Directed Palladium-Catalyzed Phosphonation of C(sp2)-H Bonds2013

    • Author(s)
      Changkun Li, Takaaki Yano, Naoki Ishida, Masahiro Murakami
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 52 Issue: 37 Pages: 9801-9804

    • DOI

      10.1002/anie.201305202

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Stereoselective Synthesis of 2,3-Dihydropyrroles from Terminal Alkynes, Azides, and α,β-Unsaturated Aldehydes via N-Sulfonyl-1,2,3-triazoles2013

    • Author(s)
      Tomoya Miura, Takamasa Tanaka, Kentaro Hiraga, Scott G. Stewart, and Masahiro Murakami
    • Journal Title

      Journal of the American Chemical Society

      Volume: 135 Issue: 37 Pages: 13652-13655

    • DOI

      10.1021/ja407166r

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 1,5-Rhodium Shift in Rearrangement of N-Arenesulfonylazetidin-3-ols into Benzosultams2013

    • Author(s)
      Naoki Ishida, Yasuhiro Shimamoto, Takaaki Yano, and Masahiro Murakami
    • Journal Title

      Journal of the American Chemical Society

      Volume: 135 Issue: 51 Pages: 19103-19106

    • DOI

      10.1021/ja410910s

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oxidative Addition of a Strained C-C Bond onto Electron-Rich Rhodium(I) at Room Temperature2013

    • Author(s)
      Yusuke Masuda, Maki Hasegawa, Makoto Yamashita, Kyoko Nozaki, Naoki Ishida, and Masahiro Murakami
    • Journal Title

      Journal of the American Chemical Society

      Volume: 135 Issue: 19 Pages: 7142-7145

    • DOI

      10.1021/ja403461f

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regiocontrolled Synthesis of Polysubstituted Pyrroles Starting from Terminal Alkynes, Sulfonyl Azides, and Allenes2013

    • Author(s)
      Tomoya Miura, Kentaro Hiraga, Tsuneaki Biyajima, Takayuki Nakamuro, and Masahiro Murakami
    • Journal Title

      Organic Letters

      Volume: 15 Issue: 13 Pages: 3298-3301

    • DOI

      10.1021/ol401340u

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Construction of Indole Skeletons by Sequential Actions of Sunlight and Rhodium on α-Amino Acetophenones2013

    • Author(s)
      Naoki Ishida, David Nečas, Yasuhiro Shimamoto, and Masahiro Murakami
    • Journal Title

      Chemistry Letters

      Volume: 42 Issue: 9 Pages: 1076-1078

    • DOI

      10.1246/cl.130463

    • NAID

      10031194347

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Doyle-Kirmse Reaction Using Triazoles Leading to One-pot Multi-functionalization of Terminal Alkynes2013

    • Author(s)
      Tomoya Miura, Takamasa Tanaka, Akira Yada, and Masahiro Murakami
    • Journal Title

      Chemistry Letters

      Volume: 42 Issue: 10 Pages: 1308-1310

    • DOI

      10.1246/cl.130521

    • NAID

      10031201348

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reactivity Change of Cyclobutanols towards Isocyanates: Rhodium Favors C-Carbamoylation over O-Carbamoylation2013

    • Author(s)
      Naoki Ishida, Yuuta Nakanishi, and Masahiro Murakami
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 52 Issue: 45 Pages: 11875-11878

    • DOI

      10.1002/anie.201306343

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of α-Amino Ketones from Terminal Alkynes via Rhodium-Catalyzed Denitrosenative Hydration of N-Sulfonyl-1,2,3-triazoles2012

    • Author(s)
      Tomoya Miura, Tsuneaki Biyajima, Tetsuji Fujii, Masahiro Murakami
    • Journal Title

      Journal of the American Chemical Society

      Volume: 134 Issue: 1 Pages: 194-196

    • DOI

      10.1021/ja2104203

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of Enaminones by Rhodium-Catalyzed Denitrogenative Rearrangement of 1-(N-Sulfonyl-1,2,3-triazole-4-yl)alkanol s2012

    • Author(s)
      Tomoya Miura, Yuuta Funakoshi, Masao Morimoto, Tsuneaki Biyajima, and Masahiro Murakami
    • Journal Title

      J. Am. Chem. Soc

      Volume: 134 Pages: 17440-17443

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rhodium-Catalyzed Ring Opening of Benzocyclobutenols with Site-Selectivity Complementary to Thermal Ring Opening2012

    • Author(s)
      Naoki Ishida, Shota Sawano, Yusuke Masuda, and Masahiro Murakami
    • Journal Title

      J. Am. Chem. Soc

      Volume: 134 Issue: 42 Pages: 17502-17504

    • DOI

      10.1021/ja309013a

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Solar-Driven Incorporation of Carbon Dioxide into α-Amino Ketones2012

    • Author(s)
      Naoki Ishida, Yasuhiro Shimamoto, Masahiro Murakami
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 51 Issue: 47 Pages: 11750-11752

    • DOI

      10.1002/anie.201206166

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] One-Pot Procedure for the Introduction of Three Different Bonds onto Terminal Alkynes through N-Sulfonyl-1,2,3-Triazole Intermediates2012

    • Author(s)
      Tomoya Miura, Takamasa Tanaka, Tsuneaki Biyajima, Akira Yada, and Masahiro Murakami
    • Journal Title

      Angew. Chem., Int. Ed.

      Volume: 52 Issue: 14 Pages: 3883-3886

    • DOI

      10.1002/anie.201209603

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of Azaaromatic-Borane Intramolecular Complexes by Palladium-Catalyzed Reaction of Azaaromatic Halides with Alkynyltriarylborates2012

    • Author(s)
      Naoki Ishida
    • Journal Title

      Helvetica Chimica Acta

      Volume: 95 Issue: 12 Pages: 2474-2480

    • DOI

      10.1002/hlca.201200554

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Selective 1:2 Coupling of Aldehydes and Allenes with Control of Regiochemistry2011

    • Author(s)
      Takeharu Toyoshima, Tomoya Miura, Masahiro Murakami
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 50 Issue: 44 Pages: 10436-10439

    • DOI

      10.1002/anie.201105077

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rhodium-Catalyzed Reaction of 1-Alkenylboronates with Aldehydes Leading to Allylation Products2011

    • Author(s)
      Hiroshi Shimizu, Tomoniro Igarashi, Tomoya Miura, Masahiro Murakami
    • Journal Title

      Angewandte Chemie, International Edition

      Volume: 50 Issue: 48 Pages: 11465-11469

    • DOI

      10.1002/anie.201105148

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] パラジウム触媒による芳香族ヨウ化物のホスホノカルボニル化反応2014

    • Author(s)
      増田 侑亮
    • Organizer
      日本化学会第94春季年会(2014)
    • Place of Presentation
      名古屋
    • Related Report
      2013 Annual Research Report
  • [Presentation] Multi-Functionalization of Terminal Alkynes2013

    • Author(s)
      Masahiro Murakami
    • Organizer
      Catalysis and Fine Chemicals 2013 (C&FC 2013)
    • Place of Presentation
      Renmin University of China
    • Year and Date
      2013-12-03
    • Related Report
      2013 Final Research Report
  • [Presentation] Formal σ-bond Metathesis between C-C Bonds and Organosilicons Catalyzed by Palladium2013

    • Author(s)
      Naoki Ishida
    • Organizer
      International Symposium on Olefin Metathesis and Related Chemistry (ISOM2013)
    • Place of Presentation
      Todaiji-temple Lecture Hall Nara
    • Year and Date
      2013-07-16
    • Related Report
      2013 Final Research Report
  • [Presentation] Pyridine-Directed Phosphonation of C(sp2)-H Bonds Catalyzed by Palladium2013

    • Author(s)
      Takaaki Yano
    • Organizer
      International Symposium on Olefin Metathesis and Related Chemistry(ISOM2013)
    • Place of Presentation
      奈良
    • Related Report
      2013 Annual Research Report
  • [Presentation] Formal σ-Bond Metathesis between C-C Bonds and Organosilicons Catalyzed by Palladium2013

    • Author(s)
      Naoki Ishida
    • Organizer
      International Symposium on Olefin Metathesis and Related Chemistry(ISOM2013)
    • Place of Presentation
      奈良
    • Related Report
      2013 Annual Research Report
  • [Presentation] Pyridine-Directed Phosphonation of C(sp2)–H Bonds Catalyzed by Palladium2013

    • Author(s)
      Takaaki Yano
    • Organizer
      第60回有機金属化学討論会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Multi-Functionalization of Terminal Alkynes2013

    • Author(s)
      Masahiro Murakami
    • Organizer
      Catalysis and Fine CHemicals
    • Place of Presentation
      北京, China
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] オルトアルキルベンゾシクロアルケノンの環拡大によるメタシクロファンの合成2013

    • Author(s)
      澤野 将太
    • Organizer
      日本化学会第93春季年会(2013)
    • Place of Presentation
      立命館大学 滋賀県
    • Related Report
      2012 Annual Research Report
  • [Presentation] ロジウム触媒を用いたトリアゾールの脱窒素水和反応によるα-アミノケトンの合成2012

    • Author(s)
      美谷島恒明・三浦智也・村上正浩
    • Organizer
      日本化学会第92春季年会(2012)
    • Place of Presentation
      横浜市慶應義塾大学
    • Year and Date
      2012-03-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] ロジウム触媒によるベンゾシクロブテノールの位置選択的開環反応: 熱的開環反応との対比2012

    • Author(s)
      澤野 将太
    • Organizer
      第59回有機金属化学討論会
    • Place of Presentation
      大阪大学 大阪府
    • Related Report
      2012 Annual Research Report
  • [Presentation] Rhodium-Catalyzed Ring Opening of Benzocylobutenols with Site-Selectivity2012

    • Author(s)
      Shota Sawano
    • Organizer
      IKCOC-12(The Twelfth International Kyoto Conference on New Aspects of Organic Chemistry)
    • Place of Presentation
      リーガロイヤルホテル京都 京都府
    • Related Report
      2012 Annual Research Report
  • [Presentation] Construction of Carbon Frameworks through Cleavage of Carbon-Carbon Single Bonds2011

    • Author(s)
      Masahiro Murakami
    • Organizer
      10th International Symposium on Organic Reaction (ISOR10)
    • Place of Presentation
      Keio University
    • Year and Date
      2011-11-23
    • Related Report
      2013 Final Research Report
  • [Presentation] Construction of Carbon Frameworks through Cleavage of Carbon-Carbon Single Bonds2011

    • Author(s)
      Masahiro Murakami
    • Organizer
      10th International Symposium on Organic Reactions (ISOR10)
    • Place of Presentation
      横浜市慶應義塾大学
    • Year and Date
      2011-11-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] パラジウム触媒による1,2,3-ベンゾトリアジン-4(3H)-オンとイソシアニドとの脱窒素環化反応2011

    • Author(s)
      西田結衣、森本将央、三浦智也、村上正浩
    • Organizer
      第58回有機金属化学討論会
    • Place of Presentation
      名古屋市名古屋大学
    • Year and Date
      2011-09-09
    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.sbchem.kyoto-u.ac.jp/murakami-lab/

    • Related Report
      2013 Final Research Report
  • [Remarks]

    • URL

      http://www.sbchem.kyoto-u.ac.jp/murakami-lab/

    • Related Report
      2011 Annual Research Report

URL: 

Published: 2011-04-06   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi