Construction of protein materials which regulate cellular functions for regenerative mediceine
| Project/Area Number |
23360364
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
KOBATAKE Eiry 東京工業大学, 総合理工学研究科(研究院), 教授 (00225484)
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| Project Period (FY) |
2011-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2013: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2012: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2011: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
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| Keywords | 生物機能工学 / 再生医工学 / 細胞機能制御 / タンパク質材料 / 組織構築 / 生体機能工学 |
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| Outline of Final Research Achievements |
In this study, protein materials which can control neural cell differentiation were constructed by integration of newly designed scaffold and signal proteins. These proteins were assembled on the substrate, and neural stem cells were cultured on the surface. Cells were differentiated to neural cells and the resulting neural tissue was maintained its neural function stably.
The basis of protein materials for regenerative medicine for neural tissue was established through this study.
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Report
(4 results)
Research Products
(24 results)
