Integrated analysis of cyanobacteriochromes in diversity and molecular regulation of cyanobacterial photoresponses

• Project/Area Number: 23370014
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Plant molecular biology/Plant physiology
• Research Institution: The University of Tokyo
• Principal Investigator: IKEUCHI Masahiko 東京大学, 総合文化研究科, 教授 (20159601)
• Co-Investigator(Renkei-kenkyūsha): FUKUYAMA Keiichi 大阪大学, 大学院・理学研究科, 教授 (80032283)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000); Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000); Fiscal Year 2012: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000); Fiscal Year 2011: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
• Keywords: 受容体 / 結晶構造 / シグナル伝達 / c-di-GMP / フィトクロム / シアノバクテリオクロム / 光受容体 / シアノバクテリア / 走光性 / 補色順化 / 細胞凝集

Research Abstract

We found that cyanobacteria possess diverse photoreceptors and cyanobacteriochromes are unique in perception of wide range of light color. We focused on biochemical, structural and physiological aspects of cyanobacteriochromes in order to integrate the light signaling system at molecular level. We determined the crystal structures of two cyanobacteriochromes and revealed the atomic basis for the color tuning and intramolecular signaling. We determined enzymatic regulation of the cyanobacteriochromes to produce or degrade a second messenger molecule, cyclic diguanylic acid, which induces cellulose production and cellular aggregation in thermophilic cyanobacteria. We also elucidated the molecular contribution of the cyanobacteriochromes to the cellular aggregation by combinatorial mutagenesis studies. Thus, a set of cyanobacteriochromes integrates various light signals into the cellulose production and cellular aggregation by direct regulation of cyclic diguanylic acid.

Research Products

• [Journal Article] Attachment of phycobilisomes in an antenna-photosystem I supercomplex of cyanobacteria (2014)
  • Author(s): Watanabe, M., Semchonok, D. A., Webber-Birungi, M., Ehira, S., Kondo, K., Narikawa, R., Ohmori, M., Boekema, E. J. and Ikeuchi, M.
  • Journal Title: Proc. Natl. Acad. Sci. USA Volume: 111 Pages: 2512-2517
  • Peer Reviewed
• [Journal Article] Klebsormidium flaccidum genome reveals primary factors for plant terrestrial adaptation (2014)
  • Author(s): K. Hori, F. Maruyama, T. Fujisawa, T. Togashi, N. Yamamoto, M. Seo, S. Sato, T. Yamada, H. Mori, N. Tajima, T. Moriyama, M. Ikeuchi, M. Watanabe, H. Wada, K. Kobayashi, M. Saito, T. Masuda, Y. Sasaki-Sekimoto, K. Mashiguchi, K. Awai, M. Shimojima, S. Masuda, M. Iwai, T. Nobusawa, T. N., S. Kondo, H. Saito, R. Sato, M. Murakawa, Y. Ihara, Y. Oshima-Yamada, K. Ohtaka, M. Satoh, K. Sonobe, M. Ishii, R. Ohtani, M. Kanamori-Sato, R. Honoki, D. Miyazaki, H. Mochizuki, J. Umetsu, K. Higashi, D. Shibata, Y. Kamiya, N. Sato, Y. Nakamura, S. Tabata, S. Ida, K. Kurokawa, and H. Ohta
  • Journal Title: Nature Comm Volume: (In press)
  • Peer Reviewed
• [Journal Article] CugP is a novel ubiquitous non-GalU-type bacterial UDP-glucose pyrophosphorylase found in cyanobacteria (2014)
  • Author(s): Maeda, K., Narikawa, R., Ikeuchi, M
  • Journal Title: J. Bacteriol. Volume: (In press)
  • Peer Reviewed
• [Journal Article] Capillary electrophoresis-mass spectrometry reveals the distribution of carbon metabolites during nitrogen starvation in Synechocystis sp. PCC 6803 (2014)
  • Author(s): Osanai
  • Journal Title: Environ Microbiol Volume: 16 Issue: 2 Pages: 512-524
  • DOI: 10.1111/1462-2920.12170
  • Peer Reviewed
• [Journal Article] Attachment of phycobilisomes in an antenna-photosystem I supercomplex of cyanobacteria (2014)
  • Author(s): Watanabe
  • Journal Title: Proc. Natl. Acad. Sci. U S A Volume: 111 Issue: 7 Pages: 2512-2517
  • DOI: 10.1073/pnas.1320599111
  • Peer Reviewed
• [Journal Article] Phycobilisome : architecture of a light-harvesting supercomplex (2013)
  • Author(s): Watanabe M., and Ikeuchi, M
  • Journal Title: Photosynth. Res Volume: 116 Pages: 265-276
  • Peer Reviewed
• [Journal Article] Structures of cyanobacteriochromes from phototaxis regulators AnPixJ and TePixJ reveal general and specific photoconversion mechanism (2013)
  • Author(s): Narikawa, R., Ishizuka, T., Muraki, N., Shiba, T., Kurisu, G. and Ikeuchi, M
  • Journal Title: Proc. Natl. Acad. Sci. USA Volume: 110 Pages: 918-23
  • Peer Reviewed
• [Journal Article] Green/red cyanobacteriochromes regulate complementary chromatic acclimation via a protochromic photocycle (2013)
  • Author(s): Hirose, Y., Rockwell, N. C., Nishiyama, K., Narikawa, R., Ukaji, Y., Inomata, K., Lagarias, J. C., Ikeuchi, M
  • Journal Title: Proc. Natl. Acad. Sci. U. S. A Volume: 110 Pages: 4974-4979
  • Peer Reviewed
• [Journal Article] Light-independent biosynthesis and assembly of the photosystem II complex in the diatom Chaetoceros gracilis (2013)
  • Author(s): Nagao
  • Journal Title: FEBS Lett Volume: 587 Issue: 9 Pages: 1340-5
  • DOI: 10.1016/j.febslet.2013.02.050
  • Peer Reviewed
• [Journal Article] DNA replication depends on photosynthetic electron transport in cyanobacteria (2013)
  • Author(s): Ohbayashi
  • Journal Title: FEMS Microbiol Lett Volume: 344 Issue: 2 Pages: 138-44
  • DOI: 10.1111/1574-6968.12166
  • Peer Reviewed
• [Journal Article] Pleiotropic effect of sigE over-expression on cell morphology, photosynthesis and hydrogen production in Synechocystis sp. PCC 6803 (2013)
  • Author(s): Osanai
  • Journal Title: Plant J Volume: 76 Issue: 3 Pages: 456-465
  • DOI: 10.1111/tpj.12310
  • Peer Reviewed
• [Journal Article] Photoconversion mechanism of the second GAF domain of cyanobacteriochrome AnPixJ and the cofactor structure of its green-absorbing state (2013)
  • Author(s): Escobar
  • Journal Title: Biochemistry Volume: 52 Issue: 29 Pages: 4871-4880
  • DOI: 10.1021/bi400506a
  • Peer Reviewed
• [Journal Article] Primary photodynamics of the green/red-absorbing photoswitching regulator of the chromatic adaptation E domain from Fremyella diplosiphon (2013)
  • Author(s): Gottlieb
  • Journal Title: Biochemistry Volume: 52 Issue: 46 Pages: 8198-8208
  • DOI: 10.1021/bi400946q
  • Peer Reviewed
• [Journal Article] Anomalous diffusion of TePixD and identification of the photoreaction product (2013)
  • Author(s): K.Kuroi, K.Tanaka, K.Okajima, M. Ikeuchi, S. Tokutomi, M.Terazim
  • Journal Title: Photochem.Photobiol.Sci. Volume: １２ Issue: 7 Pages: 1180-1186
  • DOI: 10.1039/c3pp25434h
  • Peer Reviewed
• [Journal Article] Structures of cyanobacteriochromes from phototaxis regulators AnPixJ and TePixJ reveal general and specific photoconversion mechanism. (2013)
  • Author(s): Narikawa R, Ishizuka T, Muraki N, Shiba T, Kurisu G, Ikeuchi M.
  • Journal Title: Proceedings of the National Academy of Sciences Volume: 110 Issue: 3 Pages: 918-923
  • DOI: 10.1073/pnas.1212098110
  • Peer Reviewed
• [Journal Article] Green/red cyanobacteriochromes regulate complementary chromatic acclimation via a protochromic photocycle (2013)
  • Author(s): Hirose, Y.
  • Journal Title: Proc. Natl. Acad. Sci. U S A Volume: 110 Issue: 13 Pages: 4974-79
  • DOI: 10.1073/pnas.1302909110
  • Peer Reviewed
• [Journal Article] The role of extracellular polysaccharides produced by the terrestrial cyanobacterium Nostoc sp. strain HK-01 in NaCl tolerance (2012)
  • Author(s): Yoshimura, H., Kotake, T., Aohara, T., Tsumuraya, Y., Ikeuchi, M. and Ohmori, M
  • Journal Title: J. Appl. Phycol Volume: 24 Pages: 237-243
  • Peer Reviewed
• [Journal Article] A deletion mutation in the spacing within the psaA core promoter enhances transcription in a cyanobacterium Synechocystis sp. PCC 6803 (2012)
  • Author(s): Midorikawa, T., Narikawa, R., and Ikeuchi, M
  • Journal Title: Plant Cell Physiol Volume: 53 Pages: 164-172
  • NAID: 10030307654
  • Peer Reviewed
• [Journal Article] Phycobilisome model with novel skeleton-like structures in a glaucocystophyte Cyanophora paradoxa (2012)
  • Author(s): Watanabe, M., Sato, M., Kondo, K., Narikawa, R. and Ikeuchi, M
  • Journal Title: Biochim. Biophys. Acta Volume: 1817 Pages: 1428-1435
  • Peer Reviewed
• [Journal Article] Identification of substrain-specific mutations by massively parallel whole-genome resequencing of Synechocystis sp. PCC 6803 (2012)
  • Author(s): Kanesaki, Y., Shiwa, Y., Tajima, N., Suzuki, M., Watanabe, S., Sato, N., Ikeuchi, M., and Yoshikawa, H
  • Journal Title: DNA Res Volume: 19 Pages: 67-79
  • Peer Reviewed
• [Journal Article] Thiol-based photocycle of the blue and teal light-sensing cyanobacteriochrome Tlr1999 (2012)
  • Author(s): Enomoto, G., Hirose, Y., Narikawa, R., and Ikeuchi, M
  • Journal Title: Biochemistry Volume: 51 Pages: 3050-3058
  • Peer Reviewed
• [Journal Article] Proteases are associated with a minor fucoxanthin chlorophyll a/c-binding protein from the diatom, Chaetoceros gracilis (2012)
  • Author(s): R. Nagao, T. Tomo, E. Noguchi, T. Suzuki, A. Okumura, R. Narikawa, I. Enami and M. Ikeuchi
  • Journal Title: Biochim. Biophys. Acta Volume: 1817 Pages: 2110-2117
  • Peer Reviewed
• [Journal Article] Time-resolved tracking of interprotein signal transduction : Synechocystis PixD-PixE complex as a sensor of light intensity (2012)
  • Author(s): Tanaka K, Nakasone Y, Okajima K, Ikeuchi M, Tokutomi S, Terazima M.
  • Journal Title: J Am Chem Soc Volume: 134 Pages: 8336-9
  • Peer Reviewed
• [Journal Article] Cell surface-associated proteins in the filamentous cyanobacterium Anabaena sp. strain PCC 7120 (2012)
  • Author(s): Yoshimura H, Ikeuchi M, Ohomori M.
  • Journal Title: Microbes Environ Volume: 27 Pages: 538-43
  • NAID: 10031125959
  • Peer Reviewed
• [Journal Article] Deletion of psbJ leads to accumulation of Psb27-Psb28 photosystem II complexes in Thermosynechococcus elongatus (2012)
  • Author(s): Nowaczyk MM, Krause K, Mieseler M, Sczibilanski A, Ikeuchi M, Rögner M
  • Journal Title: Biochim Biophys Acta Volume: 1817 Pages: 1339-45
  • Peer Reviewed
• [Journal Article] Cloning, expression, crystallization and preliminary X-ray studies of the ferredoxin-NAD(P) + reductase from the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1 (2012)
  • Author(s): Liauw P, Mashiba T, Kopczak M, Wiegand K, Muraki N, Kubota H, Kawano Y, Ikeuchi M, Hase T, Rögner M, Kurisu G
  • Journal Title: Acta Crystallogr Sect F Struct Biol Cryst Commun Volume: 68 Pages: 1048-51
  • Peer Reviewed
• [Journal Article] Thiol-based photocycle of the blue and teal light–sensing cyanobacteriochrome Tlr1999 (2012)
  • Author(s): Enomoto, G.
  • Journal Title: Biochemistry Volume: 51 Issue: 14 Pages: 3050-3058
  • DOI: 10.1021/bi300020u
  • Peer Reviewed
• [Journal Article] Time-Resolved Tracking of Interprotein Signal Transduction: Synechocystis PixD-PixE complex as a Sensor of Light Intensity (2012)
  • Author(s): K. Tanaka, Y. Nakasone, K. Okajima, M. Ikeuchi, S. Tokutomi, M. Terazima
  • Journal Title: J.Am.Chem.Soc Volume: 134 Issue: 20 Pages: 8336-8339
  • DOI: 10.1021/ja301540r
  • Peer Reviewed
• [Journal Article] Cloning, expression, crystallization and preliminary X-ray studies of the ferredoxin-NAD(P)+reductase from the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1. (2012)
  • Author(s): Liauw P, Mashiba T, Kopczak M, Wiegand K, Muraki N, Kubota H, Kawano Y, Ikeuchi M, Hase T, Rogner M, Kurisu G.
  • Journal Title: Acta Crystallographica Section F Volume: 68 Issue: 9 Pages: 1048-1051
  • DOI: 10.1107/s1744309112031910
  • Peer Reviewed
• [Journal Article] Novel supercomplex organization of Photosystem I in Anabaena and Cyanophora paradoxa (2011)
  • Author(s): Watanabe, M., Kubota, H., Wada, H., Narikawa, R. and Ikeuchi, M
  • Journal Title: Plant Cell Physiol Volume: 52 Pages: 162-168
  • NAID: 10029708156
  • Peer Reviewed
• [Journal Article] The cyanobacteriochrome, TePixJ, isomerizes its own chromophore by converting phycocyanobilin to phycoviolobilin (2011)
  • Author(s): Ishizuka, T., Kamiya, A., Suzuki, H., Narikawa, R., Noguchi, T., Kohchi, T., Inomata, K., and Ikeuchi, M
  • Journal Title: Biochemistry Volume: 50 Pages: 953-961
  • Peer Reviewed
• [Journal Article] Roles of PsbI and PsbM in photosystem II dimer formation and stability studied by deletion mutagenesis and X-ray crystallography (2011)
  • Author(s): Kawakami, K., Umena, Y., Iwai, M., Kawabata, Y., Ikeuchi, M., Kamiya, N. and Shen, J. -R.
  • Journal Title: Biochim. Biophys. Acta Volume: 1807 Pages: 319-325
  • Peer Reviewed
• [Journal Article] Macromolecular crowding effects on reactions of TePixD (Tll0078) (2011)
  • Author(s): Toyooka T, Tanaka K, Okajima K, Ikeuchi M, Tokutomi S, and Terazima M.
  • Journal Title: Photochem Photobiol Volume: 87 Pages: 584-9
  • NAID: 120005593641
  • Peer Reviewed
• [Journal Article] Cellulose accumulation and a cellulose synthase gene are responsible for cell aggregation in the cyanobacterium Thermosynechococcus vulcanus RKN (2011)
  • Author(s): Kawano, Y., Saotome, T., Ochiai, Y., Katayama, M., Narikawa, R. and Ikeuchi, M
  • Journal Title: Plant Cell Physiol Volume: 52 Pages: 957-66
  • NAID: 10029711659
  • Peer Reviewed
• [Journal Article] Genetic engineering of the group 2 sigma factor SigE widely activates the expressions of sugar catabolic genes in Synechocystis sp. PCC 6803 (2011)
  • Author(s): Osanai, T., Oikawa, A., Azuma, M., Tanaka, K., Saito, K., Hirai, M. Y., and Ikeuchi, M
  • Journal Title: J Biol Chem Volume: 286 Pages: 30962-71
  • Peer Reviewed
• [Journal Article] Light-induced conformational change and transient dissociation reaction of the BLUF photoreceptor Synechocystis PixD (Slr1694) (2011)
  • Author(s): Tanaka, K., Nakasone, Y., Okajima, K., Ikeuchi, M., Tokutomi, S., and Terazima, M.
  • Journal Title: J. Mol. Biol Volume: 409 Pages: 773-85
  • NAID: 120003203917
  • Peer Reviewed
• [Journal Article] A way to sense light intensity : Multiple-excitation of the BLUF photoreceptor TePixD suppresses conformational change (2011)
  • Author(s): Tanaka, K., Nakasone, Y., Okajima, K., Ikeuchi, M., Tokutomi, S., and Terazima, M.
  • Journal Title: FEBS Lett Volume: 585 Pages: 786-90
  • Peer Reviewed
• [Journal Article] Genomic structure of the cyanobacterium Synechocystis sp. PCC 6803 strain GT-S (2011)
  • Author(s): Tajima, N., Sato, S., Maruyama, F., Kaneko, T., Sasaki, N. V., Kurokawa, K., Ohta, H., Kanesaki, Y., Yoshikawa, H., Tabata, S., Ikeuchi, M., and Sato, N
  • Journal Title: DNA Res Volume: 18 Pages: 393-9
  • Peer Reviewed
• [Journal Article] Photoconversion mechanism of a green/red photosensory cyanobacteriochrome AnPixJ : time-resolved optical spectroscopy and FTIR analysis of the AnPixJ-GAF2 domain (2011)
  • Author(s): Fukushima Y, Iwaki M, Narikawa R, Ikeuchi M, Tomita Y, Itoh S.
  • Journal Title: Biochemistry Volume: 50 Pages: 6328-39
  • Peer Reviewed
• [Journal Article] Photosystem II gold nanoparticle conjugate as a nanodevice for the development of artificial light-driven water-splitting systems (2011)
  • Author(s): Noji, T. Suzuki., H., Gotoh, T., Iwai, M., Ikeuchi, M., Tomo, T. and Noguchi, T
  • Journal Title: J. Phys. Chem. Lett Volume: 2 Pages: 2448-2452
  • Peer Reviewed
• [Journal Article] Novel photosensory two-component system (PixA-NixB-NixC) involved in the regulation of positive and negative phototaxis of cyanobacterium Synechocystis sp. PCC 6803 (2011)
  • Author(s): Narikawa, R., Suzuki, F., Yoshihara, S., Higashi, S., Watanabe, M. and Ikeuchi, M.
  • Journal Title: Plant Cell Physiol Volume: 52 Pages: 2214-2224
  • NAID: 10030306738
  • Peer Reviewed
• [Journal Article] Cellulose accumulation and a cellulose synthase gene are responsible for cell aggregation in the cyanobacterium Thermosynechococcus vulcanus RKN (2011)
  • Author(s): Kawano, et al.
  • Journal Title: Plant Cell Physiology Volume: 52 Issue: 6 Pages: 957-966
  • DOI: 10.1093/pcp/pcr047
  • Peer Reviewed
• [Journal Article] Genetic engineering of the group 2 sigma factor SigE widely activates the expressions of sugar catabolic genes in Synechocystis sp.PCC 6803 (2011)
  • Author(s): Osanai, et al.
  • Journal Title: J.Biological Chemistry Volume: 286 Pages: 30962-71
  • Peer Reviewed
• [Journal Article] Genomic structure of the cyanobacterium Synechocystis sp.PCC 6803 strain GT-S (2011)
  • Author(s): Tajima, et al.
  • Journal Title: DNA Research Volume: 18 Pages: 393-9
  • Peer Reviewed
• [Presentation] 3つのシアノバクテリオクロム型光受容体がもつc-di-GMPシグナリングへの寄与 (2014)
  • Author(s): 榎本元
  • Organizer: 日本植物生理学会
  • Place of Presentation: 富山
• [Presentation] Structure and Color Development mechanism of Cyanobacteriochromes (2013)
  • Author(s): M. Ikeuchi
  • Place of Presentation: ベルリン自由大学
  • Year and Date: 2013-09-20
  • Invited
• [Presentation] Chromatic sensors in cyanobacteria (2013)
  • Author(s): M. Ikeuchi
  • Organizer: Australia 6th Asia and Oceania Conference on Photobiology
  • Place of Presentation: Sydney
  • Invited
• [Presentation] A novel bifunctional cyanobacteriochrome (2013)
  • Author(s): M. Ikeuchi
  • Organizer: German conference on photoreceptors
  • Place of Presentation: Sydney
  • Invited
• [Presentation] Color tuning in cyanobacterial life (2013)
  • Author(s): M. Ikeuchi
  • Organizer: Cyanobacterial Workshop
  • Place of Presentation: St. Louis, USA
  • Invited
• [Presentation] Chromatic sensors in cyanobacteria (2013)
  • Author(s): Ikeuchi
  • Organizer: 6th Asia and Oceania Conference on Photobiology
  • Place of Presentation: Sydney, Australia
  • Invited
• [Presentation] A novel bifunctional cyanobacteriochrome (2013)
  • Author(s): Ikeuchi
  • Organizer: German conference on photoreceptors
  • Place of Presentation: Ringberg, Germany
  • Invited
• [Presentation] Analysis of local structure of proteins that bind to isoalloxazine ring (2013)
  • Author(s): 鈴木布美子
  • Organizer: 日本ゲノム微生物学会
  • Place of Presentation: 長浜バイオ大学（滋賀県）
• [Presentation] シアノバクテリオクロム型光受容体によるc-di-GMPシグナリングの酵素学的考察 (2013)
  • Author(s): 榎本元
  • Organizer: 日本植物生理学会
  • Place of Presentation: 岡山大学（岡山県）
• [Presentation] Light-induced biofilm formation and EPS production in cyanobacteria (2012)
  • Author(s): J Tamura, R Nomura, T Saotome, Y Kawano, G Enomoto, T Shimada, R Narikawa, M Ikeuchi
  • Place of Presentation: Naantali, Finland
  • Invited
• [Presentation] Diversity of Cyanobacteriochromes and photoresponses in cyanobacteria --photocycle of double Cys-type (2012)
  • Author(s): M. Ikeuchi
  • Organizer: Gordon Research Conferences : Photosensory Receptors & Signal Transduction
  • Place of Presentation: GRC, Galveston, USA
  • Invited
• [Presentation] Creation of chimera photoreceptors to develop various light switches for effective photosynthesis-based bioenergy production (2012)
  • Author(s): 成川礼
  • Organizer: ISPP
  • Place of Presentation: Porto, Portgal
• [Presentation] c-di-GMP Signaling in Thermophilic Cyanobacteria (2012)
  • Author(s): 池内昌彦
  • Organizer: 日本フィンランド二国間セミナー
  • Place of Presentation: Naantali, Finland
  • Invited
• [Presentation] Cyanobacteriochrome Tlr1999 as a teal-light-activated c-di-GMP phosphodiesterase (2012)
  • Author(s): 榎本元
  • Organizer: ISPP
  • Place of Presentation: Porto, Portgal
• [Presentation] Diversity of cyanobacteriochromes and photoresponses in cyanobacteria (2012)
  • Author(s): 池内昌彦
  • Organizer: IPMB
  • Place of Presentation: Jeju, Korea
  • Invited
• [Presentation] Diversity of Cyanobacteriochromes and photoresponses in cyanobacteria-photocycle of double Cys-type- (2012)
  • Author(s): 池内昌彦
  • Organizer: ゴードン会議
  • Place of Presentation: アメリカ・ガルベストン(招待講演)
• [Book] 藻類オイル生産技術研究の最前線 (2013)
  • Author(s): 広瀬侑, 池内昌彦
  • Publisher: エヌ・ティー・エス
• [Book] 理系総合のための生命科学第3版 (2013)
  • Author(s): 池内昌彦
  • Publisher: 羊土社
• [Book] 藻類オイル生産技術研究の最前線 (2013)
  • Author(s): 広瀬侑
  • Total Pages: 228
  • Publisher: エヌ・ティー・エス
• [Book] 藻類ハンドブック (2012)
  • Author(s): 池内昌彦
  • Publisher: エヌ・ティー・エス
• [Book] エッセンシャル生物学 (2011)
  • Author(s): 池内昌彦, 他監訳
  • Total Pages: 551
  • Publisher: 丸善出版
• [Remarks]
  • URL: https://sites.google.com/site/whatsnewikeuchilab/
• [Remarks] 池内・成川光合成研究室
  • URL: http://photosynthesis.c.u-tokyo.ac.jp/indexJ.html
• [Remarks]
  • URL: http://photosynthesis.c.u-tokyo.ac.jp/indexJ.html