Molecular anaysis of CUC2 functional specificity

• Project/Area Number: 23370023
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Plant molecular biology/Plant physiology
• Research Institution: Nara Institute of Science and Technology
• Principal Investigator: AIDA Mitsuhiro 奈良先端科学技術大学院大学, バイオサイエンス研究科, 准教授 (90311787)
• Co-Investigator(Kenkyū-buntansha): FERJANI Ali 東京学芸大学, 教育学部, 助教 (20530380)
• Co-Investigator(Renkei-kenkyūsha): TAKAHASHI Hiro 中部大学, 応用生物学部, 講師 (30454367)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000); Fiscal Year 2013: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2012: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2011: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
• Keywords: 転写因子 / シロイヌナズナ / 発生 / 生殖 / 進化 / 遺伝子発現

Outline of Final Research Achievements

Morphogenesis of organisms is regulated by various types of proteins. Among such regulatory proteins, transcription factors constitute a major class of proteins that turn on and off gene expression. CUC2 is a transcription factor required for normal development of various plant organs including leaves and fruits. We investigated the function of CUC2 in detail using the model plant Arabidopsis thaliana (thale cress), and found mechanisms that confer different functions in development of the two organ types.

Research Products

• [Journal Article] The CUP-SHAPED COTYLEDON2 and 3 genes have a post-meristematic effect on Arabidopsis thaliana phyllotaxis. (2015)
  • Author(s): Burian A, Raczyńska-Szajgin M, Borowska-Wykręt D, Piatek A, Aida M, Kwiatkowska D
  • Journal Title: Annals of Botany Volume: 115 Issue: 5 Pages: 807-820
  • DOI: 10.1093/aob/mcv013
  • Peer Reviewed
• [Journal Article] The CUC1 and CUC2 genes promote carpel margin meristem formation during Arabidopsis gynoecium development (2014)
  • Author(s): Kamiuchi Y, Yamamoto K, Furutani M,Tasaka M, Aida M
  • Journal Title: Frontiers in Plant Science Volume: 5 Pages: 165-165
  • DOI: 10.3389/fpls.2014.00165
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] An integrative model of the control of ovule primordia formation. (2013)
  • Author(s): Galbiati F, Sinha Roy D, Simonini S, Cucinotta M, Ceccato L, Cuesta C, Simaskova M, Benkova E, Kamiuchi Y, Aida M, Weijers D, Simon R, Masiero S, Colombo L
  • Journal Title: Plant Journal Volume: 76 Issue: 3 Pages: 446-455
  • DOI: 10.1111/tpj.12309
  • Peer Reviewed
• [Journal Article] Interactions of CUP-SHAPED COTYLEDON and SPATULA genes control carpel margin development in Arabidopsis thaliana (2012)
  • Author(s): Nahar MAU, Ishida T, Smyth DR, Tasaka M, Aida M
  • Journal Title: Plant & Cell Physiology Volume: 53 Issue: 6 Pages: 1134-1143
  • DOI: 10.1093/pcp/pcs057
  • NAID: 10030805843
  • Peer Reviewed
• [Presentation] Shoot meristem formation: core mechanism and its modification. (2015)
  • Author(s): Mitsuhiro Aida
  • Organizer: 第56回日本植物生理学会年会 シンポジウム "Ectopic meristems and developmental plasticity in plants"
  • Place of Presentation: 東京農業大学 世田谷キャンパス（東京都世田谷区）
  • Year and Date: 2015-03-16 – 2015-03-18
  • Invited
• [Presentation] Coordination of embryonic shoot meristem formation by CUC1 and CUC2. (2014)
  • Author(s): Aida M, Kariya A, Tsubakimoto Y, Shimizu S, Ogisu O, Kamiya M, Taniguchi Y, Takeda S, Tasaka M.
  • Organizer: 第38回 内藤コンファレンス Molecule-Based Biological Systems (生物システムの物質的基盤)
  • Place of Presentation: シャトレーゼ ガトーキングダム サッポロ（北海道札幌市）
  • Year and Date: 2014-10-07 – 2014-10-10
• [Presentation] Regional interaction during flower primordium formation. (2014)
  • Author(s): Mitsuhiro Aida
  • Organizer: 第55回日本植物生理学会年会
  • Place of Presentation: 富山大学, 富山県富山市
  • Invited
• [Presentation] どうやって袋を作るのか～心皮の発生について (2013)
  • Author(s): MOST Altaf-Un-Nahar, 神内悠里, 辻野理恵子, 相田光宏
  • Organizer: 遺伝学研究所研究会「イネ分子遺伝学の未来」
  • Place of Presentation: 国立遺伝学研究所, 静岡県三島市
  • Invited
• [Presentation] Meristem formation in the Arabidopsis shoot and its modification (2012)
  • Author(s): Mitsuhiro Aida
  • Organizer: 5th International PhD School
  • Place of Presentation: Certosa di Pontignano, Siena, Italy
  • Invited
• [Presentation] メリステムでせめぎ合い (2011)
  • Author(s): 相田光宏
  • Organizer: 遺伝学研究所研究会「イネ分子遺伝学の飛躍」
  • Place of Presentation: 国立遺伝学研究所(招待講演)
  • Year and Date: 2011-11-19
• [Presentation] Shoot Meristem Formation in the Arabidopsis Embryo.
  • Author(s): Mitsuhiro Aida
  • Organizer: NAIST未来開拓コロキウム A New Generation of Plant Embryo Research
  • Place of Presentation: 奈良先端科学技術大学院大学, 奈良県生駒市
  • Invited
• [Remarks] 植物発生学（相田研究室）のホームページ
  • URL: http://bsw3.naist.jp/aida/?cate=385
• [Remarks] 植物発生学 (相田研究室)
  • URL: http://bsw3.naist.jp/courses/courses108.html
• [Remarks] Plant Developmental Biology
  • URL: https://sites.google.com/site/maidalab/home/research
• [Remarks] 新学術領域研究 植物細胞壁機能の情報処理システム -研究成果-
  • URL: https://www.plantcellwall.jp/research/index.php?y=2013#/pro
• [Remarks]
  • URL: http://bsw3.aist-nara.ac.jp/courses/courses108.html
• [Remarks]
  • URL: http://bsw3.naist.jp/aida/