Post-translatioinal modification in plant meristem

• Project/Area Number: 23370026
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Plant molecular biology/Plant physiology
• Research Institution: The Institute of Physical and Chemical Research
• Principal Investigator: SUGIMOTO Keiko 独立行政法人理化学研究所, 環境資源科学研究センター, チームリーダー (30455349)
• Co-Investigator(Kenkyū-buntansha): ISHIDA Takashi 熊本大学, 特任助教 (00462656) ; KOMAKI Shinichiro 理化学研究所, 環境資源科学研究センター, 特別研究員 (50584588)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000); Fiscal Year 2013: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000); Fiscal Year 2012: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000); Fiscal Year 2011: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
• Keywords: 細胞増殖 / 細胞分化 / 翻訳後修飾 / SUMO化 / 植物メリステム / シロイヌナズナ / 細胞周期 / プロテオーム

Research Abstract

Balanced progression of cell proliferation and differentiation is a prerequisite for organ growth in multicellular organisms. In the plant meristem, some daughter cells that derive from self-renewing stem cells eventually committee to differentiate but how this transition is regulated is not well understood at the molecular level. In this study we investigated how HIGH PLOIDY1 (HPY1) and HPY2 mediate the transition from proliferation into differentiation in the Arabidopsis meristem.

Research Products

• [Journal Article] Differential regulation of B2-type CDK accumulation in Arabidopsis roots (2014)
  • Author(s): Okushima, Y., Shimizu, K., Ishida, T., Sugimoto, K. and Umeda, M.
  • Journal Title: Plant Cell Rep. Volume: 33 Issue: 7 Pages: 1033-1040
  • DOI: 10.1007/s00299-014-1581-z
  • NAID: 120006537389
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] The ATM-dependent DNA damage response acts as an upstream trigger for compensation in the fas1 mutation during Arabidopsis leaf development (2013)
  • Author(s): Hisagana T, Ferjani A, Horiguchi G, Ishikawa N, Fujikura U, Kubo M, Demura T, Fukuda H, Ishida T, Sugimoto K, Tsukaya H
  • Journal Title: Plant Physiol. Volume: 162(2) Issue: 2 Pages: 831-841
  • DOI: 10.1104/pp.113.216796
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Jasmonate controls leaf growth by repressing cell proliferation and the onset of endoreduplication while maintaining a potential stand-by mode (2013)
  • Author(s): Noir S, Bomer M, Takahashi N, Ishida T, Tsui TL, Balbi V, Shanahan H, Sugimoto K, Devoto A
  • Journal Title: Plant Physiol Volume: 161(4) Issue: 4 Pages: 1930-1951
  • DOI: 10.1104/pp.113.214908
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Transcriptional repression of the APC/C activator CCS52A1 promotes the active termination of cell growth. (2012)
  • Author(s): Breuer C, Morohashi K, Kawamura A, Takahashi N. Ishida T, Umeda M, Grotewold E, and Sugimoto K.
  • Journal Title: EMBO J Volume: 7(10) Issue: 24 Pages: 4488-4801
  • DOI: 10.1038/emboj.2012.294
  • Peer Reviewed
• [Journal Article] Arabidopsis PIZZA has the capacity to acylate brassinosteroids. (2012)
  • Author(s): Schneider K, Breuer C, Kawamura A, Jikumaru Y, Hanada A, Fujioka S, Ichikawa T, Kondou Y, Minami M, Kamiya Y, Yamaguchi S, and Sugimoto K.
  • Journal Title: PLoS ONE Volume: 7(10) Issue: 10 Pages: e46805-e46805
  • DOI: 10.1371/journal.pone.0046805
  • Peer Reviewed
• [Journal Article] MMS21/HPY2 and SIZ1, two Arabidopsis SUMO E3 ligases, have distinct functions in development (2012)
  • Author(s): Ishida T, Yoshimura M, Miura K, Sugimoto K
  • Journal Title: PLos ONE Volume: 7(10) Issue: 10 Pages: e46897-e46897
  • DOI: 10.1371/journal.pone.0046897
  • Peer Reviewed
• [Journal Article] Tuning growth to the environmental demands (2012)
  • Author(s): 10)Rymen, B., Sugimoto, K
  • Journal Title: Curr Opin in Plant Biol Volume: 5 Issue: 6 Pages: 683-690
  • DOI: 10.1016/j.pbi.2012.07.005
  • Peer Reviewed
• [Journal Article] Control of the plant cell cycle by developmental and environmental cues (2012)
  • Author(s): Komaki S, Sugimoto K
  • Journal Title: Plant Cell Physiol Volume: 53(6) Issue: 6 Pages: 953-964
  • DOI: 10.1093/pcp/pcs070
  • NAID: 10030804927
  • Peer Reviewed
• [Journal Article] 植物におけるSUMOシステムとE3リガーゼの機能 (2012)
  • Author(s): 石田喬志, 杉本慶子
  • Journal Title: 生化学 Volume: 84(6) Pages: 440-447
  • NAID: 10030809429
  • URL: http://ci.nii.ac.jp/naid/10030809429
  • Peer Reviewed
• [Journal Article] 細胞増殖から見た個体サイズの制御機構 (2011)
  • Author(s): 小牧伸一郎, 杉本慶子
  • Journal Title: 植調 Volume: 45(9) Pages: 363-372
• [Presentation] Transcriptional control of cell differentiation in optimizing plant growth (2014)
  • Author(s): Rymen B
  • Organizer: 第55回日本植物生理学会年会
  • Place of Presentation: 富山大学, 富山県
  • Year and Date: 2014-03-19
• [Presentation] 細胞周期の制御に関与するGRASファミリー転写因子 (2014)
  • Author(s): 鈴木俊哉
  • Organizer: 第55回日本植物生理学会年会
  • Place of Presentation: 富山大学, 富山県
  • Year and Date: 2014-03-18
• [Presentation] The Anaphase-Promoting Complex/Cyclosome Regulates Microtubule Structures through the Cell Cycle (2014)
  • Author(s): Komaki S
  • Organizer: 第55回日本植物生理学会年会
  • Place of Presentation: 富山大学, 富山県
  • Year and Date: 2014-03-18
• [Presentation] Transcriptional control of cell differentiation in optimizing plant growth (2014)
  • Author(s): Rymen B，Mitsuda N, Ohme-Takagi N，Matsui M，Sugimoto,K
  • Organizer: 第５５回日本植物生理学会年会
  • Place of Presentation: 富山大学、富山県
• [Presentation] 細胞周期の制御に関与する GRAS ファミリー転写因子 (2014)
  • Author(s): 鈴木俊哉、Christian Breuer, 石田喬志、杉本慶子、伊藤正樹
  • Organizer: 第５５回日本植物生理学会年会
  • Place of Presentation: 富山大学 富山県
• [Presentation] The Anaphase-Promoting Complex/ Cyclosome Regulates Microtubule Structures through the Cell Cycle (2014)
  • Author(s): Komaki S, Ishida T, Heyman J, Hamada T, Hashimoto T, De Veylder L, Sugimoto K.
  • Organizer: 第５５回日本植物生理学会年会
  • Place of Presentation: 富山大学 富山県
• [Presentation] Endocycling up the path of plant development (2013)
  • Author(s): Sugimoto. K
  • Organizer: University of California Davis
  • Place of Presentation: UC Davis, USA
  • Year and Date: 2013-10-30
• [Presentation] Endocycling up the path of plant development (2013)
  • Author(s): Sugimoto K
  • Organizer: North Carolina State University
  • Place of Presentation: NCSU, USA
  • Year and Date: 2013-10-28
• [Presentation] Activity of the anaphase-promoting complex/cyclosome is required for the cell cycle transition and the endocycle progression (2013)
  • Author(s): 小牧伸一郎
  • Organizer: 第54回日本植物生理学会年会
  • Place of Presentation: 岡山大学, 岡山県
  • Year and Date: 2013-03-21
• [Presentation] Endocycling up the path of plant development (2013)
  • Author(s): Sugimoto K
  • Organizer: University of California Davis, USA
  • Place of Presentation: University of California Davis, USA
  • Invited
• [Presentation] Endocycling up the path of plant development (2013)
  • Author(s): Sugimoto K
  • Organizer: North Carolina State University, USA
  • Place of Presentation: North Carolina State University, USA
  • Invited
• [Presentation] ACTIVITY OF THE ANAPHASE-PROMOTING COMPLEX/CYCLOSOME IS REQUIRED FOR THE CELL CYCLE TRANSITION AND THE ENDOCYCLE PROGRESSION (2013)
  • Author(s): 小牧 伸一郎
  • Organizer: 日本植物生理学会第54回大会
  • Place of Presentation: 岡山大学、岡山県
• [Presentation] HPY1 is required for both mitotic cycle and endocycle regulation in Arabidopsis (2012)
  • Author(s): Komaki S
  • Organizer: ICAR2012
  • Place of Presentation: Vienna, Austria
  • Year and Date: 2012-07-03
• [Presentation] The ATM-Dependent DNA Damage Response Acts as an Upstream Trigger for Compensation in the fas1 Mutation during Arabidopsis Leaf Development (2012)
  • Author(s): Hisanaga T
  • Organizer: ICAR2012
  • Place of Presentation: Vienna, Austria
  • Year and Date: 2012-07-03
• [Presentation] 細胞分裂周期から核内倍加周期への移行制御メカニズムの解析 (2012)
  • Author(s): 小牧伸一郎
  • Organizer: 第53回日本植物生理学会年会
  • Place of Presentation: 京都府京都市
  • Year and Date: 2012-03-17
• [Presentation] HPY1 IS REQUIRED FOR BOTH MITOTIC CYCLE AND ENDOCYCLE REGULATION IN ARABIDOPSIS (2012)
  • Author(s): Komaki S
  • Organizer: ICAR2012
  • Place of Presentation: Vienna, Austria
• [Presentation] ATM-DEPENDENT DNA DAMAGE RESPONSE COORDINATES CELL PROLIFERATION AND CELL EXPANSION IN ARABIDOPSIS LEAF GROWTH (2012)
  • Author(s): Hisanaga T
  • Organizer: ICAR2012
  • Place of Presentation: Vienna, Austria
• [Presentation] Controlling the transition from cell proliferation to cell differentiation (2011)
  • Author(s): Komaki S
  • Organizer: ICAR2011
  • Place of Presentation: 倉敷市, 岡山県
  • Year and Date: 2011-12-08
• [Presentation] Controlling the transition from cell proliferation to cell differentiation (2011)
  • Author(s): Shinichiro Komaki, Keiko Sugimoto
  • Organizer: International symposium on strategies of plants against global environmental change
  • Place of Presentation: 岡山県倉敷市
  • Year and Date: 2011-12-08
• [Presentation] 細胞増殖から分化への移行メカニズム (2011)
  • Author(s): 小牧伸一郎, 杉本慶子
  • Organizer: 新学術領域研究「植物環境突破力」第二回若手の会
  • Place of Presentation: 静岡県浜松市
  • Year and Date: 2011-11-01
• [Presentation] 植物メリステム領域における細胞周期制御機構の解析 (2011)
  • Author(s): 小牧伸一郎, 杉本慶子
  • Organizer: 平成23年度特定領域研究「植物メリステム」若手ワークショップ
  • Place of Presentation: 滋賀県高島市
  • Year and Date: 2011-10-13
• [Remarks]
  • URL: http://cellfunction.riken.jp/
• [Remarks] Cell Function Research Team
  • URL: http://cellfunction.riken.jp/
• [Remarks] 独立行政法人理化学研究所環境資源科学研究センター細胞機能研究チームホームページ
  • URL: http://cellfunction.riken.jp/Research.html
• [Remarks]
  • URL: http://labs.psc.riken.jp/cfru/index.html