Development of a non-destructive detector of unsuitable chicken eggs in influenza vaccine production
| Project/Area Number |
23380148
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Agricultural environmental engineering
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OHASHI Shintaro 新潟大学, 自然科学系, 助教 (70452076)
NAKANO Takayuki 鹿児島純心女子大学, 看護栄養学部, 教授 (30155783)
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| Research Collaborator |
TAKIZAWA Ken-ichi 新潟大学, 自然科学研究科, 博士研究員
KIMURA Kohei 新潟大学, 自然科学研究科, 大学院生
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
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| Keywords | インフルエンザワクチン / 有精卵 / 非破壊検査 / 透過光 / 中死卵 / 不適卵 / LED / インフルエンザ / ワクチン / ＬＥＤ / 検卵装置 |
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| Research Abstract |
In Japan, fertilized chicken eggs are used to produce influenza vaccines. However, some eggs do not develop and then contaminate the vaccine stock solution, which causes large economic losses and raises health concerns. Therefore, a non-destructive test that allows distinction of normal and unsuitable chicken eggs was developed, using visible and near-infrared (VNIR) spectroscopy and a light-emitting diode (LED) light source.
Linear discriminant analysis was applied using wavelength absorbance data to distinguish between normal and unsuitable eggs, and all of the optical absorbance values of the normal eggs were found to be higher than those of unsuitable eggs. The rate of discrimination between the two types of eggs exceeded 97% when linear discriminant analysis and two wavelengths in the visible light range were used.
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Report
(4 results)
Research Products
(12 results)
