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Development of a non-destructive detector of unsuitable chicken eggs in influenza vaccine production

Research Project

Project/Area Number 23380148
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Agricultural environmental engineering
Research InstitutionNiigata University

Principal Investigator

NAKANO Kazuhiro  新潟大学, 自然科学系, 教授 (70188994)

Co-Investigator(Kenkyū-buntansha) OHASHI Shintaro  新潟大学, 自然科学系, 助教 (70452076)
NAKANO Takayuki  鹿児島純心女子大学, 看護栄養学部, 教授 (30155783)
Research Collaborator TAKIZAWA Ken-ichi  新潟大学, 自然科学研究科, 博士研究員
KIMURA Kohei  新潟大学, 自然科学研究科, 大学院生
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Keywordsインフルエンザワクチン / 有精卵 / 非破壊検査 / 透過光 / 中死卵 / 不適卵 / LED / インフルエンザ / ワクチン / LED / 検卵装置
Research Abstract

In Japan, fertilized chicken eggs are used to produce influenza vaccines. However, some eggs do not develop and then contaminate the vaccine stock solution, which causes large economic losses and raises health concerns. Therefore, a non-destructive test that allows distinction of normal and unsuitable chicken eggs was developed, using visible and near-infrared (VNIR) spectroscopy and a light-emitting diode (LED) light source.
Linear discriminant analysis was applied using wavelength absorbance data to distinguish between normal and unsuitable eggs, and all of the optical absorbance values of the normal eggs were found to be higher than those of unsuitable eggs. The rate of discrimination between the two types of eggs exceeded 97% when linear discriminant analysis and two wavelengths in the visible light range were used.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (12 results)

All 2013 2012 Other

All Journal Article (4 results) Presentation (8 results)

  • [Journal Article] 農産物・食品の安全と品質の確保技術-第2回 異常鶏卵の非破壊検出とその応用-2013

    • Author(s)
      中野和弘・臼井善彦
    • Journal Title

      農業機械学会誌

      Volume: 75巻 Pages: 364-368

    • NAID

      130004714184

    • Related Report
      2013 Final Research Report
  • [Journal Article] DEVELOPMENT OF A NONDESTRUCTIVE DETECTOR OF UNSUITABLE CHICKEN EGGS USING LED LIGHTS FOR INFLUENZA VACCINE PRODUCTION2013

    • Author(s)
      Kohei KIMURA, Kazuhiro NAKANO, Shintaroh OHASHI, Kenichi TAKIZAWA, Takayuki NAKANO
    • Journal Title

      Proceedings of the 5th International Conference on Trends in Agricultural Engineering

      Pages: 324-329

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] 農産物・食品の安全と品質の確保技術-第2回 異常鶏卵の非破壊検出とその応用-2013

    • Author(s)
      中野和弘・臼井善彦
    • Journal Title

      農業機械学会誌

      Volume: 75 Pages: 364-368

    • NAID

      130004714184

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Development of a non-destructive detector of unsuitable chicken eggs for use in influenza vaccine production2012

    • Author(s)
      Kohei Kimura, Kazuhiro Nakano, Shintaroh Ohashi and Takayuki Nakano
    • Journal Title

      Proceedings of the 7th Asian Conference for Information Technology in Agriculture

      Volume: (CD-ROM 版)

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
  • [Presentation] インフルエンザワクチン製造不適卵の非破壊検出装置の開発2013

    • Author(s)
      木村孝平・中野和弘・大橋慎太郎・滝沢憲一
    • Organizer
      農業食料工学会第72回年次大会
    • Place of Presentation
      帯広畜産大学(帯広市)
    • Year and Date
      2013-09-12
    • Related Report
      2013 Final Research Report
  • [Presentation] LED光源によるインフルエンザワクチン製造不適卵の判別2013

    • Author(s)
      木村孝平・中野和弘・大橋慎太郎
    • Organizer
      2013年度農業施設学会大会
    • Place of Presentation
      岐阜大学(岐阜市)
    • Year and Date
      2013-08-30
    • Related Report
      2013 Final Research Report
  • [Presentation] ワクチン製造用有精卵の非破壊検卵装置の開発2013

    • Author(s)
      木村孝平・中野和弘・大橋慎太郎・滝沢憲一・金子昌彦・佐々木靖文・中野隆之
    • Organizer
      第11回食品産業分野への実験力学的手法の応用に関する研究会
    • Place of Presentation
      燕三条地場産業振興センター(三条市)
    • Year and Date
      2013-05-11
    • Related Report
      2013 Final Research Report
  • [Presentation] LED光源によるインフルエンザ・ワクチン製造不適卵の判別2013

    • Author(s)
      木村孝平・中野和弘・大橋慎太郎
    • Organizer
      2013年度農業施設学会大会
    • Place of Presentation
      岐阜大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] インフルエンザワクチン製造不適卵の非破壊検出装置の開発2013

    • Author(s)
      木村孝平・中野和弘・大橋慎太郎・滝沢憲一
    • Organizer
      農業食料工学会第72回年次大会
    • Place of Presentation
      帯広畜産大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] インフルエンザワクチン製造不適卵の非破壊検出装置の開発2012

    • Author(s)
      木村孝平・中野和弘・大橋慎太郎・滝沢憲一・金子昌彦・佐々木靖文・中野隆之
    • Organizer
      農業環境工学関連学会2012年合同大会
    • Place of Presentation
      宇都宮大学(宇都宮市)
    • Year and Date
      2012-09-13
    • Related Report
      2013 Final Research Report
  • [Presentation] インフルエンザワクチン製造不適卵の非破壊検出装置の開発2012

    • Author(s)
      木村孝平・中野和弘・大橋慎太郎・滝沢憲一・金子昌彦・佐々木靖文・中野隆之
    • Organizer
      農業環境工学関連学会2012年合同大会
    • Place of Presentation
      宇都宮大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] ワクチン製造用有精卵の非破壊検卵装置の開発

    • Author(s)
      木村孝平・中野和弘・大橋慎太郎・滝沢憲一・金子昌彦・佐々木靖文・中野隆之
    • Organizer
      第11回食品産業分野への実験力学的手法の応用に関する研究会
    • Place of Presentation
      燕三条地場産業振興センター
    • Related Report
      2013 Annual Research Report

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Published: 2011-04-06   Modified: 2019-07-29  

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