| Project/Area Number |
23380160
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | National Agriculture and Food Research Organization |
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Principal Investigator |
KUSHIBIKI Shiro 独立行政法人農業・食品産業技術総合研究機構, 家畜生理栄養研究領域, 上席研究員 (30355218)
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| Co-Investigator(Renkei-kenkyūsha) |
SHINGU Hiroyuki 独立行政法人農業・食品産業技術総合研究機構畜産草地研究所, 家畜生理栄養研究領域, 主任研究員 (40355219)
KOBAYASHI Hisami 独立行政法人農業・食品産業技術総合研究機構畜産草地研究所, 家畜生理栄養研究領域, 研究員 (80609701)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2013: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2011: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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| Keywords | 子牛 / ラクトフェリン / セロビオース / 発育 / サイトカイン / ホルモン |
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| Research Abstract |
In this study, the calves were fed lactoferrin (LF), which is absorbed by the small intestine and improves immune functions, and cellobiose (CB), which volatile fatty acids (VFA) (a substance that is converted to nutrients in the large intestines) and activates nutrient metabolism. We also evaluated the synchronization effect of LF and CB. Growth, nutrient metabolism, and immune functions improved after LF or CB were given. LF and CB were identified as functionality components that contribute to healthy long-term growth from the suckling to rearing period. In particular, the suppression of growth retardation during the weaning period is a new finding of this study. On the other hand, a synchronized effect was not observed because independent supply of LF and CB both sufficiently stabilized the biological functions.
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