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Effects of early life stress on brain plasticity

Research Project

Project/Area Number 23390040
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field General anatomy (including Histology/Embryology)
Research InstitutionNara Medical University

Principal Investigator

NISHI Mayumi  奈良県立医科大学, 医学部, 教授 (40295639)

Co-Investigator(Kenkyū-buntansha) AZUMA Cho  奈良県立医科大学, 医学部, 講師 (90326322)
HORII Noriko  奈良県立医科大学, 医学部, 助教 (80433332)
Co-Investigator(Renkei-kenkyūsha) HAYASHI Yasunori  理化学研究所, シナプス機能研究チーム, チームリーダー (90466037)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2013: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2012: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2011: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Keywords母子分離 / ストレス / c-Fos / コルチコステロイド / 扁桃体延長領域 / 視床下部―下垂体―副腎系 / ペリニューロナルネット / エンドカンナビノイド / 視床下部ー下垂体ー副腎系 / 臨界期 / 分界条床核 / 扁桃体中心核 / PTSD / 馴化
Research Abstract

We investigated effects of early life stress on brain plasticity by using mouse maternal separation (MS), which provides one avenue for delving into the mechanisms mediating interactions between genes and environment. We found that the blood level of stress hormone, corticosterone, increased at adult stage, neuronal activity in the extended amygdala was promoted, and the expression level of several genes regulating learning and memory including endocannabinoid was altered. Furthermore, we observed some behavioral changes such as decrease in aversive memory, motivation for palatable foods in the adulthood.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (116 results)

All 2014 2013 2012 2011 Other

All Journal Article (19 results) (of which Peer Reviewed: 18 results,  Open Access: 1 results) Presentation (84 results) (of which Invited: 3 results) Book (10 results) Remarks (3 results)

  • [Journal Article] Distribution of corticosteroid receptors in mature oligodendrocytes and oligodendrocyte progenitors of the adult mouse brain2014

    • Author(s)
      Matsusue M, Horii-Hayashi N, Kirita T, Nishi M
    • Journal Title

      J Histochem Cytochem

    • Related Report
      2013 Final Research Report
  • [Journal Article] Distribution of corticosteroid receptors in mature oligodendrocytes and oligodendrocyte progenitors of the adult mouse brain.2014

    • Author(s)
      Matsusue M, Horii-Hayashi N, Kirita T, Nishi M
    • Journal Title

      J Histochem Cytochem

      Volume: 62 Issue: 3 Pages: 211-226

    • DOI

      10.1369/0022155413517700

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of early life stress on brain activity : Implications from maternal separation in rodents2013

    • Author(s)
      Nishi M, Horii-Hayashi N, Sasagawa T, Matsunaga W
    • Journal Title

      General and Comparative Endocrinol

      Volume: 181 Pages: 306-309

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Developmental changes in desensitization of c-Fos expression induced by repeated maternal separation in pre-weaned mice2013

    • Author(s)
      Horii-Hayashi N, Sasagawa T, Matsunaga W, Matsusue Y, Azuma C, Nishi M
    • Journal Title

      J Neuroendocrinol

      Volume: 25 Pages: 158-67

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of early life stress on brain activity: Implications from maternal separation in rodents.2013

    • Author(s)
      Nishi M, Horii-Hayashi N, Sasagawa T, Matsunaga W
    • Journal Title

      General and Comparative Endocrinol

      Volume: 181 Pages: 306-309

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Developmental changes in desensitization of c-Fos expression induced by repeated maternal separation in pre- weaned mice.2013

    • Author(s)
      Horii-Hayashi N, Sasagawa T, Matsunaga W, Matsusue Y, Azuma C, Nishi M
    • Journal Title

      J Neuroendocrinol.

      Volume: 25 Issue: 2 Pages: 158-167

    • DOI

      10.1111/j.1365-2826.2012.02377.x

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of early life stress on brain activity: Implications from maternal separation in rodents2013

    • Author(s)
      Nishi M
    • Journal Title

      General and Comparative Endocrinol

      Volume: 181 Pages: 306-309

    • DOI

      10.1016/j.ygcen.2012.09.024

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Imaging of corticosteroid receptors in live cells2012

    • Author(s)
      Nishi M
    • Journal Title

      Methods in Enzymology

      Volume: 505 Pages: 347-361

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid signaling of steroid hormones in the vertebrate nervous system : a comparative insight from fish to mammals2012

    • Author(s)
      Sakamoto H, Takahashi H, Matsuda K-I, Nishi M, Takanami K, Ogoshi M, Sakamoto T, Kawata M
    • Journal Title

      Front Biosci

      Volume: 17 Pages: 996-1019

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 幼少期のストレスが脳の可塑性に及ぼす影響2012

    • Author(s)
      西真弓, 堀井-林謹子, 笹川誉世, 松永渉
    • Journal Title

      日本生理学雑誌

      Volume: 74 Pages: 216-217

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of SIK3 in glucose and lipid homeostasis in mice2012

    • Author(s)
      Uebi T, Itoh Y, Hatano O, Kumagai A, Sanosaka M, Sasaki T, Sasagawa S, Doi J, Tatsumi K, Mitamura K, Morii E, Aozasa K, Kawamura T, Okumura M, Nakae J, Takikawa H, Fukusato T, Koura M, Nishi M, Hamsten A, Silveira A, Bertorello AM, Kitagawa K, Nagaoka Y, Kawahara H, Tomonaga T, Naka T, Ikegawa S, Tsumaki N, Matsuda J, Takemori H
    • Journal Title

      PLoS ONE

      Volume: 7

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Imaging of corticosteroid receptors in live cells.2012

    • Author(s)
      Nishi M
    • Journal Title

      Methods in Enzymology.

      Volume: 505 Pages: 347-361

    • DOI

      10.1016/b978-0-12-388448-0.00026-7

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid signaling of steroid hormones in the vertebrate nervous system2012

    • Author(s)
      Sakamoto H, Takahashi H, Matsuda K I, Nishi M, Takanami K, Ogoshi M, Sakamoto T, Kawata M
    • Journal Title

      Frontiers in Bioscience

      Volume: 17 Issue: 1 Pages: 996-1019

    • DOI

      10.2741/3970

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of SIK3 in glucose and lipid homeostasis in mice2012

    • Author(s)
      Uebi T, Itoh Y, Hatano O, Kumagai A, Sanosaka M, Sasaki T, Sasagawa S, Doi J, Tatsumi K, Mitamura K, Morii E, Aozasa K, Kawamura T, Okumura M, Nakae J, et al.
    • Journal Title

      PLoS One

      Volume: 7 Issue: 5 Pages: e37803-e37803

    • DOI

      10.1371/journal.pone.0037803

    • URL

      https://pure.teikyo.jp/en/publications/61105694-b2ad-4886-8e7f-6ebfbfa91849

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamics of corticosteroid receptors : implications from live cell imaging2011

    • Author(s)
      Nishi M
    • Journal Title

      Acta Histochem Cytochem

      Volume: 44 Pages: 1-7

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Environmental stimulation changes tissue-type plasminogen activator activity in the adult mouse hippocampus2011

    • Author(s)
      Horii-Hayashi N, Yoshikawa M, Nishi M, Wanaka A
    • Journal Title

      Neurochem Int

      Volume: 58 Pages: 1-4

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo assessment of peripheral nerve regeneration by diffusion tensor imaging2011

    • Author(s)
      Morisaki S, Kawai Y, Umeda M, Nishi M, Oda R, Fujiwara H, Yamada K, Higuchi T, Tanaka C, Kawata M, Kubo T
    • Journal Title

      J of Magn Res Imag

      Volume: 33 Pages: 535-542

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intranuclear Dynamics of Corticosteroid Receptors and Effects of Proteasomal Activity in Cultured Hippocampal Neural Cells2011

    • Author(s)
      Nishi M, Horii-Hayashi N, Kawata M
    • Journal Title

      Neurosci Lett

      Volume: 494 Pages: 65-69

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamics of Corticosteroid Receptors: Lessons from Live Cell Imaging2011

    • Author(s)
      Nishi M
    • Journal Title

      ACTA HISTOCHEMICA ET CYTOCHEMICA

      Volume: 44 Issue: 1 Pages: 1-7

    • DOI

      10.1267/ahc.10028

    • NAID

      130000395310

    • ISSN
      0044-5991, 1347-5800
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 視床下部領域に新たに同定されたペリニューロナルネット陽性細胞を含む神経領域について2014

    • Author(s)
      西真弓
    • Organizer
      第119回日本解剖学会総会・全国学術集会
    • Place of Presentation
      栃木
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] 幼少期ストレスによる食物嗜好性行動への影響2014

    • Author(s)
      笹川誉世
    • Organizer
      第119回日本解剖学会総会・全国学術集会
    • Place of Presentation
      栃木
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] 早期母子分離と, 成体マウスの側坐核および分界上床核における遺伝子発現変化2014

    • Author(s)
      橋本隆
    • Organizer
      第119回日本解剖学会総会・全国学術集会
    • Place of Presentation
      栃木
    • Related Report
      2013 Final Research Report
  • [Presentation] Different Accumulation of Elements in the Tracheal and Bronchial Cartilage of Monkey2014

    • Author(s)
      東超
    • Organizer
      第119回日本解剖学会総会・全国学術集会
    • Place of Presentation
      栃木
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] A novel hypothalamic area enriched with perineuronal nets2014

    • Author(s)
      Noriko Horii
    • Organizer
      神経糖鎖生物学国際シンポジウム
    • Place of Presentation
      淡路島
    • Related Report
      2013 Final Research Report
  • [Presentation] 早期母子分離と、成体マウスの側坐核および分界上床核における遺伝子発現変化2014

    • Author(s)
      橋本隆、笹川誉世、堀井謹子、西真弓
    • Organizer
      第119回日本解剖学会総会・全国学術集会
    • Place of Presentation
      栃木
    • Related Report
      2013 Annual Research Report
  • [Presentation] A novel hypothalamic area enriched with perineuronal nets.2014

    • Author(s)
      Noriko Horii, Takayo Sasagawa, Takashi Hashimoto, Mayumi Nishi
    • Organizer
      神経糖鎖生物学国際シンポジウム
    • Place of Presentation
      淡路島
    • Related Report
      2013 Annual Research Report
  • [Presentation] 幼少期のストレスが脳の可塑性に及ぼす影響2013

    • Author(s)
      西真弓
    • Organizer
      産業医科大学セミナー
    • Place of Presentation
      北九州
    • Year and Date
      2013-12-17
    • Related Report
      2013 Final Research Report
  • [Presentation] 「行動と神経科学」幼少期のストレスが脳の可塑性に及ぼす影響2013

    • Author(s)
      西真弓
    • Organizer
      日本医科大学
    • Place of Presentation
      東京
    • Year and Date
      2013-11-22
    • Related Report
      2013 Final Research Report
  • [Presentation] 母子分離による脳内 c-Fos 発現変化と成長後の行動への影響2013

    • Author(s)
      笹川誉世
    • Organizer
      日本行動神経内分泌研究会(JSBN) 第3回関西支部勉強会(兼 生体制御学スプリングプログラム)
    • Place of Presentation
      岡山
    • Year and Date
      2013-03-08
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of early life stress on brain activity : Implications from maternal separation in rodents2013

    • Author(s)
      Takayo Sasagawa
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego
    • Related Report
      2013 Final Research Report
  • [Presentation] 視床下部領域に新たに同定されたペリニューロナルネット陽性細胞を含む神経核について2013

    • Author(s)
      堀井謹子
    • Organizer
      第40回日本神経内分泌学会学術集会
    • Place of Presentation
      宮崎(若手研究奨励賞受賞)
    • Related Report
      2013 Final Research Report
  • [Presentation] 長残光蛍光体ナノ粒子を用いた光バイオイメージング2013

    • Author(s)
      多喜正泰
    • Organizer
      第54回日本組織細胞化学会総会・学術集会, シンポジウム「生体イメージングの最前線」
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 転写共役因子 SAFB のラット脳内局在およびエストロゲン受容体αとの共存2013

    • Author(s)
      橋本隆
    • Organizer
      第54回日本組織細胞化学会総会・学術集会, シンポジウム「生体イメージングの最前線」
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] GFP イメージングの基礎と応用2013

    • Author(s)
      西真弓
    • Organizer
      第38回日本組織細胞化学会講習会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] ペリニューロナルネット陽性神経細胞を含む視床下部新規神経核について2013

    • Author(s)
      堀井-林謹子
    • Organizer
      第19回日本行動神経内分泌研究会全国集会
    • Place of Presentation
      鹿児島
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] 出生後のペリニューロナルネット形成の脳地図2013

    • Author(s)
      松永渉
    • Organizer
      第36回日本神経科学大会
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] 視床下部領域に新たに同定されたペリニューロナルネット陽性細胞を含む神経核について2013

    • Author(s)
      堀井謹子
    • Organizer
      第36回日本神経科学大会
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] WFA 染色によるペリニューロナルネット発現変化の脳地図2013

    • Author(s)
      西真弓
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      高松
    • Related Report
      2013 Final Research Report
  • [Presentation] 転写共役因子 SAFB の脳内局在とエストロゲン受容体αとの共存2013

    • Author(s)
      橋本隆
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      高松
    • Related Report
      2013 Final Research Report
  • [Presentation] Developmental changes in desensitization of c-Fos expression induced by repeated maternal separation in pre-weaned mice2013

    • Author(s)
      笹川誉世
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      高松
    • Related Report
      2013 Final Research Report
  • [Presentation] 日本神経科学会における取り組み2013

    • Author(s)
      西真弓
    • Organizer
      第118回日本解剖学会総会・全国学術集会ワークショップ「男女共同参画をどう進めるか~他学会の経験に学ぶ」
    • Place of Presentation
      高松
    • Related Report
      2013 Final Research Report
  • [Presentation] 幼少期のストレスが脳の可塑性におよぼす影響について : 母子分離モデルによる解析2013

    • Author(s)
      西真弓
    • Organizer
      第118回日本解剖学会総会・全国学術集会, シンポジウム「生育環境と脳発達」
    • Place of Presentation
      高松
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of early life stress on brain activity : implications from maternal separation model in rodents2013

    • Author(s)
      Mayumi Nishi
    • Organizer
      第90回日本生理学会大会 日本神経科学学会連携シンポジウム 「Mother-child interaction influences the brain functions of mother and child」
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 長残光蛍光体ナノ粒子を用いた癌細胞および細胞外マトリックスの無励起光型バイオイメージング2013

    • Author(s)
      西真弓
    • Organizer
      科学技術振興機構研究成果展開事業 産学共創基礎基盤研究「産学共創の場」
    • Place of Presentation
      淡路島
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of early life stress on brain activity: Implications from maternal separation in rodents2013

    • Author(s)
      Takayo Sasagawa, Norio Horii-Hayashi, Takashi Hashimoto, Mayumi Nishi
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego
    • Related Report
      2013 Annual Research Report
  • [Presentation] 視床下部領域に新たに同定されたペリニューロナルネット陽性細胞を含む神経核について2013

    • Author(s)
      堀井謹子、笹川誉世、橋本隆、西真弓
    • Organizer
      第40回日本神経内分泌学会学術集会
    • Place of Presentation
      宮崎
    • Related Report
      2013 Annual Research Report
  • [Presentation] 長残光蛍光体ナノ粒子を用いた光バイオイメージング2013

    • Author(s)
      多喜正泰、西真弓、田部世津久、石田昭人
    • Organizer
      第54回日本組織細胞化学会総会・学術集会、シンポジウム「生体イメージングの最前線」
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 転写共役因子SAFBのラット脳内局在およびエストロゲン受容体αとの共存2013

    • Author(s)
      橋本隆、松田賢一、西真弓、河田光博
    • Organizer
      第54回日本組織細胞化学会総会・学術集会、シンポジウム「生体イメージングの最前線」
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] GFPイメージングの基礎と応用2013

    • Author(s)
      西真弓
    • Organizer
      第38回日本組織細胞化学会講習会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Developmental changes in desensitization of c-Fos expression induced by repeated maternal separation in pre-weaned mice.2013

    • Author(s)
      笹川誉世
    • Organizer
      118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      高松
    • Related Report
      2012 Annual Research Report
  • [Presentation] WFA染色によるペリニューロナルネット発現変化の脳地図2013

    • Author(s)
      西真弓
    • Organizer
      118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      高松
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of early life stress on brain activity : implications from maternal separation model in rodents.2013

    • Author(s)
      Mayumi Nishi
    • Organizer
      第90回日本生理学会大会(日本神経科学学会連携シンポジウム「Mother-child interaction influences the brain functions of mother and child」)
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] 幼少期のストレスが脳の可塑性におよぼす影響について:母子分離モデルによる解析2013

    • Author(s)
      西真弓
    • Organizer
      第118回日本解剖学会総会・全国学術集会 (シンポジウム「生育環境と脳発達」)
    • Place of Presentation
      高松
    • Related Report
      2012 Annual Research Report
  • [Presentation] 長残光蛍光体ナノ粒子を用いた癌細胞および細胞外マトリックスの無励起光型バイオイメージング2013

    • Author(s)
      西真弓
    • Organizer
      科学技術振興機構 研究成果展開事業 産学共創基礎基盤研究「産学共創の場」
    • Place of Presentation
      淡路島
    • Related Report
      2012 Annual Research Report
  • [Presentation] 母子分離による脳内c-Fos発現変化と成長後の行動への影響2013

    • Author(s)
      笹川誉世
    • Organizer
      日本行動神経内分泌研究会(JSBN) 第3回関西支部勉強会(兼 生体制御学スプリングプログラム)
    • Place of Presentation
      岡山
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脳とストレス2012

    • Author(s)
      西真弓
    • Organizer
      京都市立堀川高等学校. 世界脳週間京都講演会「ようこそ脳科学の最先端へ」
    • Place of Presentation
      京都
    • Year and Date
      2012-06-16
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of early life stress on brain plasticity2012

    • Author(s)
      Mayumi Nishi, Noriko Horii-Hayashi, Takayo Sasagawa, Wataru Matsunaga
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      松本(シンポジウム)
    • Year and Date
      2012-03-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] 母子分離ストレスが脳の可塑性に及ぼす影響2012

    • Author(s)
      西真弓、堀井-林謹子、笹川誉世、松末友美子、松永渉
    • Organizer
      第117回日本解剖学会総会・全国学術集会
    • Place of Presentation
      山梨(一般演題)
    • Year and Date
      2012-03-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 光るタンパク質2012

    • Author(s)
      西真弓
    • Organizer
      藤島高校コアSSH プログラム「福井県にゆかりのある科学からノーベル賞の科学へ」
    • Place of Presentation
      福井
    • Year and Date
      2012-01-29
    • Related Report
      2013 Final Research Report
  • [Presentation] 光るタンパク質2012

    • Author(s)
      西真弓
    • Organizer
      藤島高校コアSSHプログラム「福井県にゆかりのある科学からノーベル賞の科学へ」
    • Place of Presentation
      福井(招待講演)
    • Year and Date
      2012-01-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] 初生期母子分離マウスにおけるPTSD 脆弱性の研究2012

    • Author(s)
      松永渉
    • Organizer
      日本行動神経内分泌研究会 第2回関西支部勉強会
    • Place of Presentation
      奈良
    • Year and Date
      2012-01-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 母子分離におけるコルチコステロン応答と脳内 c-Fos 発現の変化2012

    • Author(s)
      堀井謹子
    • Organizer
      第39回日本神経内分泌学会学術集会
    • Place of Presentation
      北九州
    • Related Report
      2013 Final Research Report
  • [Presentation] 転写共役因子 SAFB の脳内局在とERαとの相互作用2012

    • Author(s)
      橋本隆
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋
    • Related Report
      2013 Final Research Report
  • [Presentation] 母子分離ストレスによる神経活動上昇2012

    • Author(s)
      笹川誉世
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋
    • Related Report
      2013 Final Research Report 2012 Annual Research Report
  • [Presentation] 単発電気刺激による母子分離マウスの行動への影響2012

    • Author(s)
      松永渉
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋
    • Related Report
      2013 Final Research Report 2012 Annual Research Report
  • [Presentation] Dynamics of corticosteroid hormone receptors : implications from live cell imaging2012

    • Author(s)
      Mayumi Nishi
    • Organizer
      4th International Symposium on Photonic bioimaging
    • Place of Presentation
      Sapporo
    • Related Report
      2013 Final Research Report
  • [Presentation] 母子分離におけるコルチコステロン応答と脳内 c-Fos 発現の変化2012

    • Author(s)
      堀井謹子
    • Organizer
      第17回日本行動神経内分泌研究会全国集会
    • Place of Presentation
      京都
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of early life adverse events on brain plasticity2012

    • Author(s)
      Mayumi Nishi
    • Organizer
      14th International Congress of Hsitochemistry and Cytochemistry
    • Place of Presentation
      Kyoto
    • Related Report
      2013 Final Research Report
  • [Presentation] Brain regions activated by maternal separation in the developing mouse : c-Fos expression after acute and repeated separation2012

    • Author(s)
      Takayo Sasagawa
    • Organizer
      14th International Congress of Histochemistry and Cytochemistry
    • Place of Presentation
      Kyoto
    • Related Report
      2013 Final Research Report
  • [Presentation] Live Cell Imaging Analysis of Nuclear Mobility of Erα : Effect of SAFB1/2 Corepressors2012

    • Author(s)
      Takashi Hashimoto
    • Organizer
      14th International Congress of Histochemistry and Cytochemistry
    • Place of Presentation
      Kyoto
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of early life stress on brain plasticity2012

    • Author(s)
      Mayumi Nish
    • Organizer
      シンポジウム「幼少期のストレスが脳の可塑性に及ぼす影響」第89回日本生理学会大会
    • Place of Presentation
      松本
    • Related Report
      2013 Final Research Report
  • [Presentation] 母子分離ストレスが脳の可塑性に及ぼす影響2012

    • Author(s)
      西真弓
    • Organizer
      第117回日本解剖学会総会・全国学術集会
    • Place of Presentation
      山梨
    • Related Report
      2013 Final Research Report
  • [Presentation] Persistent left hepatic venous directly opening into the right atrium2012

    • Author(s)
      東超
    • Organizer
      第117回日本解剖学会総会・全国学術集会
    • Place of Presentation
      山梨
    • Related Report
      2013 Final Research Report
  • [Presentation] Distribution of corticosteroid receptors in oligodendrocytes of mice2012

    • Author(s)
      Yumiko Matsusue
    • Organizer
      第117回日本解剖学会総会・全国学術集会
    • Place of Presentation
      山梨
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of early life environments on the brain plasticity2012

    • Author(s)
      Nishi M
    • Organizer
      The 7th AOSCE Congress
    • Place of Presentation
      Kuala Lumpur, MALAYSIA
    • Related Report
      2013 Final Research Report
  • [Presentation] 母子分離におけるコルチコステロン応答と脳内c-Fos発現の変化2012

    • Author(s)
      堀井謹子
    • Organizer
      第39回日本神経内分泌学会学術集会
    • Place of Presentation
      北九州
    • Related Report
      2012 Annual Research Report
  • [Presentation] 転写共役因子SAFBの脳内局在とERαとの相互作用2012

    • Author(s)
      橋本隆
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Annual Research Report
  • [Presentation] Dynamics of corticosteroid hormone receptors: implications from live cell imaging.2012

    • Author(s)
      Mayumi Nishi
    • Organizer
      4th International Symposium on Photonic bioimaging
    • Place of Presentation
      札幌
    • Related Report
      2012 Annual Research Report
  • [Presentation] 母子分離におけるコルチコステロン応答と脳内c-Fos発現の変化2012

    • Author(s)
      堀井謹子
    • Organizer
      第17回日本行動神経内分泌研究会全国集会
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of early life adverse events on brain plasticity2012

    • Author(s)
      Mayumi Nishi
    • Organizer
      14th International Congress of Hsitochemistry and Cytochemistry (Workshop: Neurobiology of social behavior)
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] Brain regions activated by maternal separation in the developing mouse: c-Fos expression after acute and repeated separation.2012

    • Author(s)
      Takayo Sasagawa
    • Organizer
      14th International Congress of Histochemistry and Cytochemistry.
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] Live Cell Imaging Analysis of Nuclear Mobility of ERα: Effect of SAFB1/2 Corepressors.2012

    • Author(s)
      Takashi Hashimoto
    • Organizer
      14th International Congress of Histochemistry and Cytochemistry.
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] ステロイドホルモンレセプターダイナミクスの蛍光イメージング2011

    • Author(s)
      西真弓
    • Organizer
      奈良女子大学ライフサイエンスセミナー
    • Place of Presentation
      奈良
    • Year and Date
      2011-01-24
    • Related Report
      2013 Final Research Report
  • [Presentation] 母子分離ストレスが脳の可塑性に及ぼす影響2011

    • Author(s)
      西真弓
    • Organizer
      第38回日本神経内分泌学会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 母子分離ストレスがもたらす神経活動上昇と大脳辺縁系におけるペリニューロナルネット形成への影響2011

    • Author(s)
      堀井-林謹子
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] マウスのオリゴデンドロサイトにおけるステロイドレセプターの分布2011

    • Author(s)
      松末友美子
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] Visualization of corticosteroid receptor interactions in living cells with GPF-based FRET2011

    • Author(s)
      Nishi M
    • Organizer
      日本組織細胞化学会 第10回日中合同組織細胞化学セミナー
    • Place of Presentation
      北京
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of early life adverse events on brain plasticity2011

    • Author(s)
      Mayumi Nishi
    • Organizer
      The First ASIA-PACIFIC Conference on Integrative Behavioral Science with Sino-Japan Integrative Symposium of Behavior and its Neuro-Mechanism
    • Place of Presentation
      Xi'an, CHINA
    • Related Report
      2013 Final Research Report
  • [Presentation] 幼少期の生育環境が脳の可塑性に与える影響2011

    • Author(s)
      西真弓
    • Organizer
      第15回日本行動神経内分泌学会シンポジウム
    • Place of Presentation
      八王子
    • Related Report
      2013 Final Research Report
  • [Presentation] 脳内コルチコステロイド受容体のダイナミクス2011

    • Author(s)
      西真弓
    • Organizer
      日本顕微鏡学会第67回学術講演会シンポジウム
    • Place of Presentation
      福岡
    • Related Report
      2013 Final Research Report
  • [Presentation] 幼少期の生育環境が脳の可塑性に与える影響2011

    • Author(s)
      西真弓
    • Organizer
      第116回日本解剖学会総会・第88回日本生理学会合同大会 シンポジウム
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] 幼少期ストレスがもたらす神経活動上昇と大脳辺縁系におけるペリニューロナルネット形成への影響2011

    • Author(s)
      堀井謹子
    • Organizer
      第116回日本解剖学会総会・第88回日本生理学会合同大会シンポジウム
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] マウスのオリゴデンドロサイトにおけるコルチコステロイドレセプターの分布2011

    • Author(s)
      松末友美子
    • Organizer
      第116回日本解剖学会総会・第88回日本生理学会合同大会 シンポジウム
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] 母子分離ストレスが脳の可塑性に及ぼす影響2011

    • Author(s)
      西真弓、堀井-林謹子、笹川誉世、松永渉
    • Organizer
      第38回日本神経内分泌学会
    • Place of Presentation
      東京(一般演題)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Visualization of corticosteroid receptor interactions in living cells with GPF-based FRET2011

    • Author(s)
      Nishi M
    • Organizer
      日本組織細胞化学会第10回日中合同組織細胞化学セミナー
    • Place of Presentation
      北京(シンポジウム)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳内コルチコステロイド受容体のダイナミクス2011

    • Author(s)
      西真弓
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜(シンポジウム)
    • Related Report
      2011 Annual Research Report
  • [Presentation] マウスのオリゴデンドロサイトにおけるステロイドレセプターの分布2011

    • Author(s)
      松末友美子、堀井-林謹子、小野勝彦、西真弓
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜(一般演題)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 母子分離ストレスがもたらす神経活動上昇と大脳辺縁系におけるペリニューロナルネット形成への影響2011

    • Author(s)
      堀井-林謹子、笹川誉世、松末友美子、西真弓
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜(一般演題)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effects of early life adverse events on brain plasticity2011

    • Author(s)
      Mayumi Nishi
    • Organizer
      The First ASIA-PACIFIC Conference on Integrative Behavioral Science with Sino-Japan Integrative Symposium of Behavior and its Neuro-Mechanism
    • Place of Presentation
      Xi'an, CHINA(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 幼少期の生育環境が脳の可塑性に与える影響2011

    • Author(s)
      西真弓、堀井-林謹子
    • Organizer
      第15回日本行動神経内分泌学会
    • Place of Presentation
      八王子(シンポジウム)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 幼少期のストレスが脳の可塑性に及ぼす影響

    • Author(s)
      西真弓
    • Organizer
      産業医科大学 セミナー
    • Place of Presentation
      北九州
    • Related Report
      2013 Annual Research Report
  • [Presentation] 行動と神経科学」幼少期のストレスが脳の可塑性に及ぼす影響

    • Author(s)
      西真弓
    • Organizer
      日本医科大学・特別講演
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 脳とストレス

    • Author(s)
      西真弓
    • Organizer
      京都市立堀川高等学校 世界脳週間京都講演会「ようこそ脳科学の最先端へ」
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Book] The Big Picture Gross Anatomy; Ed. David Morton, Kurt Albertine, 翻訳(分担執筆:Section2 : Torax 胸部・胸郭)2014

    • Author(s)
      西真弓
    • Publisher
      Bo Foreman, McGraw Hill books
    • Related Report
      2013 Final Research Report
  • [Book] The Big Picture: Gross Anatomy2014

    • Author(s)
      西真弓
    • Total Pages
      512
    • Publisher
      McGraw Hill books
    • Related Report
      2013 Annual Research Report
  • [Book] カラーアトラス機能組織学 原著第2版. 監修 : 河田光博, 小路武彦(分担執筆:免疫系, 呼吸器系)2013

    • Author(s)
      西真弓
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2013 Final Research Report
  • [Book] GFPイメージングの基礎と応用.日本組織細胞化学編. 組織細胞化学2013

    • Author(s)
      西真弓
    • Publisher
      学際企画, 東京
    • Related Report
      2013 Final Research Report
  • [Book] カラーアトラス機能組織学 原著第2版2013

    • Author(s)
      西真弓
    • Total Pages
      499
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2013 Annual Research Report
  • [Book] 日本組織細胞化学編 GFPイメージングの基礎と応用2013

    • Author(s)
      西真弓
    • Total Pages
      184
    • Publisher
      学際企画
    • Related Report
      2013 Annual Research Report
  • [Book] カラーイラストで学ぶ 集中講義 解剖学2013

    • Author(s)
      西真弓
    • Total Pages
      496
    • Publisher
      メジカルビュー社
    • Related Report
      2013 Annual Research Report
  • [Book] カラーアトラス機能組織学 原著第2版.2013

    • Author(s)
      西真弓
    • Total Pages
      499
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2012 Annual Research Report
  • [Book] カラーイラストで学ぶ 集中講義解剖学(分担執筆 : 血液, 造血器, 内分泌), 坂井建雄編集2012

    • Author(s)
      西真弓
    • Publisher
      メジカルビュー社
    • Related Report
      2013 Final Research Report
  • [Book] カラーイラストで学ぶ 集中講義 解剖学2012

    • Author(s)
      西真弓
    • Total Pages
      483
    • Publisher
      メジカルビュー社
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.naramed-u.ac.jp/~1ana/

    • Related Report
      2013 Final Research Report
  • [Remarks] 奈良県立医科大学・第一解剖学教室ホームページ

    • URL

      http://www.naramed-u.ac.jp/~1ana/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 奈良県立医科大学第一解剖学教室ホームページ

    • URL

      http://www.naramed-u.ac.jp/~1ana/

    • Related Report
      2012 Annual Research Report

URL: 

Published: 2011-04-06   Modified: 2019-07-29  

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