| Project/Area Number |
23390177
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Osaka City University |
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Principal Investigator |
HAYASHI TOMOSHIGE 大阪市立大学, 医学(系)研究科(研究院), 准教授 (10381980)
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| Co-Investigator(Kenkyū-buntansha) |
SATO Kyoko 大阪市立大学, 大学院・医学研究科, 講師 (00381989)
ENDO Ginji 大阪市立大学, 大学院・医学研究科, 教授 (20160393)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2013: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2012: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2011: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
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| Keywords | 内臓脂肪 / 疫学 / 生活習慣病 / 日系人 / 前向きコホート研究 / 国際情報交換 / アメリカ / コホート研究 |
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| Research Abstract |
We had enrolled 1649 subjects between 2005 and 2010 to examine the association between visceral adiposity and fat liver measured by computed tomography (CT), and the risk of future lifestyle-related diseases.
Intraclass correlation coefficients for intra- and inter-reader comparisons of the measurement of fatty liver showed a good reliability. In the prospective analyses, visceral adiposity was associated with an increased risk of the future type 2 diabetes, hypertension, hypertriglycerides, and low high-density lipoprotein (HDL) cholesterol independent of fatty liver, age, and gender. On the other hand, fatty liver was associated with an increased risk of the future type 2 diabetes and low HDL cholesterol, not hypertension or hypertriglycerides, independent of visceral fat, age, and gender.
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