• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of multidisciplinary therapy based on mechanism of liver insufficiency in a use of Aged partial graft after liver transplantation.

Research Project

Project/Area Number 23390324
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Digestive surgery
Research InstitutionThe University of Tokushima

Principal Investigator

SHIMADA Mitsuo  徳島大学, ヘルスバイオサイエンス研究部, 教授 (10216070)

Co-Investigator(Kenkyū-buntansha) YASUTOMO Koji  徳島大学, ヘルスバイオサイエンス研究部, 教授 (30333511)
TANAKA Shinji  東京医科歯科大学, 情報処理センター, 科学技術振興特別特認准教授 (30253420)
IMURA Satoru  徳島大学, 病院, 助教 (90380021)
MORINE Yuji  徳島大学, 病院, 助教 (60398021)
TAKEDA Eiji  徳島大学, ヘルスバイオサイエンス研究部, 教授 (00144973)
UTSUNOMIYA Toru  徳島大学, ヘルスバイオサイエンス研究部, 准教授 (30304801)
IKEMOTO Tetsuya  徳島大学, ヘルスバイオサイエンス研究部, 助教 (20398019)
KATAGIRI Toyomasa  徳島大学, 疾患プロテオゲノム研究センター, 教授 (60291895)
OYADOMARI Seiichi  徳島大学, 疾患プロテオゲノム研究センター, 教授 (90502534)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2013: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2012: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2011: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Keywords肝不全 / 加齢肝 / 幹細胞 / 加齢遺伝子 / マイクロダイアライシス
Research Abstract

The majority of liver transplantation in Japan is living donor liver transplantation. As aging population has recently been increasing, aged liver of a donor candidate has become a most problem. We gave similar surgical insults as liver transplantation, including ischemia-reperfusion injury and massive hepatectomy in the aged liver. We obtained several novel findings regarding the mechanisms, by which aging induced liver functional and regenerative insufficiency. We also found some possible therapeutic agents and strategies including ADRC, HDAC inhibitor and the others, which may improve the liver dysfunction and may support liver regeneration in these animal models.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (76 results)

All 2014 2013 2012 2011

All Journal Article (40 results) (of which Peer Reviewed: 40 results) Presentation (36 results)

  • [Journal Article] Specific molecular signatures of non-tumor liver tissue may predict a risk of hepatocarcinogenesis2014

    • Author(s)
      Utsunomiya T, Shimada M, Morine Y, Tajima A, Imoto I
    • Journal Title

      Cancer Sci

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The gene profile in the spleen under massive partial hepatectomy using cDNA microarray and pathway analysis2014

    • Author(s)
      Arakawa Y, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Mori H, Kanamoto M, Iwahashi S, Saito Y, Takasu C
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 印刷中 Issue: 8 Pages: 1645-1653

    • DOI

      10.1111/jgh.12573

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Abrogation of Rbpj attenuates experimental autoimmune uveoretinitis by inhibiting IL-22-producing CD4+ T cells2014

    • Author(s)
      Bhuyan ZA, Asanoma M, Iwata A, Ishifune C, Maekawa Y, Shimada M, Yasutomo K
    • Journal Title

      PLoS One

      Volume: 9(2) Issue: 2 Pages: e89266-e89266

    • DOI

      10.1371/journal.pone.0089266

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cytokine expression in spleen affects progression of liver cirrhosis through liver-spleen cross-talk2014

    • Author(s)
      Asanoma M, Ikemoto T, Mori H, Utsunomiya T, Imura S, Morine Y, Iwahashi S, Saito Y, Yamada S, Shimada M
    • Journal Title

      Hepatol Res

      Volume: 印刷中 Issue: 12 Pages: 1217-1223

    • DOI

      10.1111/hepr.12267

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] A hydrolyzed whey peptide-based diet ameliorates hepatic ischemia-reperfusion injury in the rat nonalcoholic fatty liver2014

    • Author(s)
      Nii A, Utsunomiya T, Shimada M, Ikegami T, Ishibashi H, Imura S, Morine Y, Ikemoto T, Sasaki H, Kawashima A
    • Journal Title

      Surg Today

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Improving allogeneic islet transplantation by suppressing Th17 and enhancing Treg with histone deacetylase inhibitors2014

    • Author(s)
      Sugimoto K, Itoh T, Takita M, Shimoda M, Chujo D, SoRelle JA, Naziruddin B, Levy MF, Shimada M, Matsumoto S
    • Journal Title

      Transpl Int

      Volume: 27(4) Issue: 4 Pages: 408-415

    • DOI

      10.1111/tri.12265

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recovery pattern of non-protein respiratory quotient and non-esterified fatty acids after liver resection2014

    • Author(s)
      Sugihara K, Yamanaka-Okumura H, Teramoto A, Urano E, Katayama T, Mori H, Utsunomiya T, Shimada M, Takeda E
    • Journal Title

      Nutrition

      Volume: 30(4) Issue: 4 Pages: 443-438

    • DOI

      10.1016/j.nut.2013.09.012

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Senescence-related genes possibly responsible for poor liver regeneration after hepatectomy in elderly patients2014

    • Author(s)
      Zhu C, Ikemoto T, Utsunomiya T, Yamada S, Morine Y, Imura S, Arakawa Y, Takasu C, Ishikawa D, Shimada M
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 29(5) Issue: 5 Pages: 1102-1108

    • DOI

      10.1111/jgh.12468

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Trophic effect of adipose tissue-derived stem cells on porcine islet cells2014

    • Author(s)
      Yamada S, Shimada M, Utsunomiya T, Ikemoto T, Saito Y, Morine Y, Imura S, Mori H, Arakawa Y, Kanamoto M, Iwahashi S
    • Journal Title

      J Surg Res

      Volume: 187(2) Issue: 2 Pages: 667-672

    • DOI

      10.1016/j.jss.2013.10.031

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preand postoperative nutritional assessment and health-related quality of life in recipients of living donor liver transplantation2014

    • Author(s)
      Urano E, Yamanaka-Okumura H, Teramoto A, Sugihara K, Morine Y, Imura S, Utsunomiya T, Shimada M, Takeda E
    • Journal Title

      Hepatol Res

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Asanoma M. Beneficial effects of enteral nutrition containing with hydrolyzed whey peptide on warm ischemia/reperfusion injury in the rat liver2014

    • Author(s)
      Hanaoka J, Shimada M, Utsunomiya T, Morine Y, Imura S, Ikemoto T, Mori H, Sugimoto K, Saito Y, Yamada S
    • Journal Title

      Hepatol Res

      Volume: 44(1) Issue: 1 Pages: 114-121

    • DOI

      10.1111/hepr.12097

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial effects of green tea catechin on massive hepatectomy model in rats2014

    • Author(s)
      Saito Y, Mori H, Takasu C, Komatsu M, Hanaoka J, Yamada S, Asanoma M, Ikemoto T, Imura S, Morine Y, Utsunomiya T, Shimada M
    • Journal Title

      J Gastroenterol

      Volume: 49(4) Issue: 4 Pages: 692-701

    • DOI

      10.1007/s00535-013-0799-9

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of a whey peptide-based enteral formula diet on liver dysfunction following living donor liver transplantation2014

    • Author(s)
      Arakawa Y, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Hanaoka J
    • Journal Title

      Surg Today

      Volume: 44(1) Issue: 1 Pages: 44-49

    • DOI

      10.1007/s00595-012-0466-4

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bevacizumab Improves Splenomegaly and Decreases Production of Hyaluronic Acid After L-OHP Based Chemotherapy.2014

    • Author(s)
      Arakawa Y, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Hanaoka J, Kanamoto M, Iwahashi S, Saito Y, Yamada S, Asanoma M, Takasu C, Bando Y.
    • Journal Title

      Anticancer Research

      Volume: 34 Pages: 1953-1958

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recent advances in estimating hepatic functional reserve in patients with chronic liver damage.2014

    • Author(s)
      Imura S, Shimada M, Utsunomiya T.
    • Journal Title

      Hepatology Research

      Volume: 印刷中 Issue: 1 Pages: 10-19

    • DOI

      10.1111/hepr.12325

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of TU-100, a traditional Japanese medicine, administered after hepatic resection in patients with liver cancer: a multi-center, phase III trial (JFMC40-1001).2014

    • Author(s)
      Shimada M , Morine Y, Nagano H, Hatano E, Kaiho T, Miyazaki M, Kono T, Kamiyama T, Morita S, Sakamoto J, Kusano M, Saji S, Kanematsu T, Kitajima M.
    • Journal Title

      Intrnational Journal of Clinical Oncology

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A hydrolyzed whey peptide-based diet ameliorates hepatic ischemia-reperfusion injury in the rat nonalcoholic fatty liver.2014

    • Author(s)
      Nii A , Utsunomiya T, Shimada M, Ikegami T, Ishibashi H, Imura S, Morine Y, Ikemoto T, Sasaki H, Kawashima A.
    • Journal Title

      Surgery Today

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial effects of green tea catechin on massive hepatectomy model in rats.2014

    • Author(s)
      Saito Y, Mori H, Takasu C, Komatsu M, Hanaoka J, Yamada S, Asanoma M, Ikemoto T, Imura S, Morine Y, Utsunomiya T, Shimada M.
    • Journal Title

      Journal of Gastroenterology

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of splenectomy on hepatic gene expression profiles after massive hepatectomy in rats2013

    • Author(s)
      Arakawa Y, Shimada M, Utsunomya T, Imura S, Morine Y, Ikemoto T, Takasu C
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 28(10) Issue: 10 Pages: 1669-1677

    • DOI

      10.1111/jgh.12316

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Significance of sonic hedgehog signaling after massive hepatectomy in a rat.2013

    • Author(s)
      Jun Hanaoka
    • Journal Title

      Surgery Today

      Volume: 50 Issue: 3 Pages: 300-307

    • DOI

      10.1007/s00595-012-0248-z

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The protective effect of adipose-derived stem cells against liver injury by trophic molecules.2013

    • Author(s)
      Yu Saito
    • Journal Title

      Journal of Surgical Research

      Volume: 180 Issue: 1 Pages: 162-168

    • DOI

      10.1016/j.jss.2012.10.009

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CXC receptor 4 and stromal cell-derived factor 1 in primary tumors and liver metastases of colorectal cancer.2013

    • Author(s)
      Yamada S, Shimada M, Utsunomiya T, Morine Y, Imura S, Ikemoto T, Mori H, Arakawa Y, Kanamoto M, Iwahashi S, Saito Y.
    • Journal Title

      Journal of Surgical Research

      Volume: 187 Issue: 1 Pages: 107-112

    • DOI

      10.1016/j.jss.2013.10.030

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Laparoscopic hepatic resection for metastatic liver tumor of colorectal cancer: comparative analysis of short- and long-term results.2013

    • Author(s)
      Iwahashi S , Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Arakawa Y, Mori H, Kanamoto M, Yamada S.
    • Journal Title

      Surgical Endoscopy

      Volume: 28 Issue: 1 Pages: 80-84

    • DOI

      10.1007/s00464-013-3165-3

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial effects of green tea catechin on massive hepatectomy model in rats.2013

    • Author(s)
      Yu Saito
    • Journal Title

      Journal of Gastroenterology

      Volume: 30

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of a new refrigerator on the preservation of hepatic grafts2012

    • Author(s)
      Kanamoto M, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Mori H, Hanaoka J
    • Journal Title

      Hepatol Res

      Volume: 42(8) Pages: 798-805

    • NAID

      10031144299

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Outcome of hepatectomy in super-elderly patients with hepatocellular carcinoma2012

    • Author(s)
      Yamada S, Shimada M, Utsunomiya T, et al.
    • Journal Title

      Hepatol res

      Volume: (in press) Issue: 5 Pages: 454-458

    • DOI

      10.1111/j.1872-034x.2011.00952.x

    • NAID

      10031144259

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Notch2 regulates the development of marginal zone B cells through Fos2012

    • Author(s)
      Iwahashi S, Maekawa Y, Nishida J, Ishifune C, Kitamura A, Arimochi H, Kataoko K, Chiba S, Shimada M, Yasutomo K
    • Journal Title

      iochem Biophys Res Commun

      Volume: 418 Issue: 4 Pages: 701-707

    • DOI

      10.1016/j.bbrc.2012.01.082

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Possible utility of MRI using Gd-EOB-DTPA for estimating liver functional reserve2012

    • Author(s)
      Utsunomiya T, Shimada M, Hanaoka J, Kanamoto M, Ikemoto T, Morine Y, Imura S, Harada M
    • Journal Title

      J Gastroenterol

      Volume: 47(4) Issue: 4 Pages: 470-476

    • DOI

      10.1007/s00535-011-0513-8

    • NAID

      10030650294

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of a new refrigerator for the preservation of whole blood2012

    • Author(s)
      Kanamoto M, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Mori H, Hanaoka J
    • Journal Title

      J Surg Res

      Volume: 173(1) Issue: 1 Pages: 180-184

    • DOI

      10.1016/j.jss.2010.09.011

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The impact of pegylated-interferon α-2b on partial and massive hepatectomy model in rats.2012

    • Author(s)
      Hiroki Mori
    • Journal Title

      Hepatogastroenterology

      Volume: 59 Pages: 2300-2304

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulatory T cells in the blood: a new marker of surgical stress.2012

    • Author(s)
      Yu Saito
    • Journal Title

      Surgery Today

      Volume: 15

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of a new refrigerator on the preservation of hepatic grafts.2012

    • Author(s)
      Mami Kanamoto
    • Journal Title

      Hepatology research

      Volume: 42 Issue: 8 Pages: 798-805

    • DOI

      10.1111/j.1872-034x.2012.00987.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of a New Refrigerator for the Preservation of Whole Blood2012

    • Author(s)
      Mami Kanamoto
    • Journal Title

      Journal of Surgical Research

      Volume: 173 Pages: 180-184

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Notch2 regulates the development of marginal zone B cells through Fos2012

    • Author(s)
      Shuich Iwahashi
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 418 Pages: 701-707

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Outcome of hepatectomy in super-elderly patients with hepatocellular carcinoma2012

    • Author(s)
      Shinichiro Yaraada
    • Journal Title

      Hepatology Research

      Volume: 42(5) Pages: 454-458

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of UCP2 expression after hepatic warm ischemia-reperfusion in the rat2011

    • Author(s)
      Ninomiya M, Shirabe K, Shimada M, Terashi T, Maehara Y
    • Journal Title

      Gut Liver

      Volume: 5(4) Issue: 4 Pages: 486-492

    • DOI

      10.5009/gnl.2011.5.4.486

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Human adipose-derived stem cells : potential clinical applications in surgery2011

    • Author(s)
      Utsunomiya T, et al.(9人中1番目)
    • Journal Title

      Surg Today

      Volume: 41(1) Issue: 1 Pages: 18-23

    • DOI

      10.1007/s00595-010-4415-9

    • NAID

      10027818310

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial effects of follistatin in hepatic ischemia-reperfusion injuries in rats2011

    • Author(s)
      Kanamoto M, Shimada M, Morine Y, Yoshizumi T, Imura S, Ikegami T, Mori H, Arakawa Y
    • Journal Title

      Dig Dis Sci

      Volume: 56(4) Issue: 4 Pages: 1075-1081

    • DOI

      10.1007/s10620-010-1401-4

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial Effects of Follistatin in Hepatic Ischemia-Reperfusion Injuries in Rats2011

    • Author(s)
      Mami Kanamoto
    • Journal Title

      Digestive Disease and Science

      Volume: 56 Pages: 1075-1081

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possible utility of MRI using Gd-EOB-DTPA for estimating liver functional reserve2011

    • Author(s)
      Tohru Utsunomiya
    • Journal Title

      Journal of Gastroenterology

      Volume: 47(4) Pages: 470-476

    • NAID

      10030650294

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Recent Advancements in Liver Surgery : Assessment of Funcional Reserve, Simulation and Navigation2013

    • Author(s)
      Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Arakawa Y , Kanamoto M, Iwahashi S, Saito Y , T akasu C, Y amada S
    • Organizer
      International Association of Surgeons, Gastroenterologists and Oncologists 2013 (IASGO2013)
    • Place of Presentation
      ルーマニア(The Palace of the Parliament)
    • Related Report
      2013 Final Research Report
  • [Presentation] The gene profile in the spleen under rat small-for-size graft model using cDNA microarray and pathway analaysis2013

    • Author(s)
      Arakawa Y , Shimada M, Ishikawa D, Y amada S, Saito Y , T akasu C, Iwahashi S, Kanamoto M, Mori H, Ikemoto T , Morine Y , Imura S, Utsunomiya T , Sato H, Miyake H
    • Organizer
      The 13th Congress of the Asian Society Of Transplantation 2013 (CAST2013)
    • Place of Presentation
      京都府(国立京都国際会館)
    • Related Report
      2013 Final Research Report
  • [Presentation] The homing effect of adipose-derived stem cells to the injured liver : The shift of stromal cellderived factor 1 expressions2013

    • Author(s)
      Saito Y , Shimada M, Utsunomiya T , Ikemoto T , Y amada S, T akasu C.
    • Organizer
      The 13th Congress of the Asian Society Of Transplantation 2013 (CAST2013)
    • Place of Presentation
      京都府(国立京都国際会館)
    • Related Report
      2013 Final Research Report
  • [Presentation] Successful management of liver transplant recipient with strongly positive donor-specific antibody against human leukocyte antigen2013

    • Author(s)
      Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Arakawa Y, Kanamoto M, Iwahashi S
    • Organizer
      International Surgical Week 2013 (SW2013)
    • Place of Presentation
      フィンランド(Helsinki Exhibition and Convention Centre)
    • Related Report
      2013 Final Research Report
  • [Presentation] 脂肪由来幹細胞を用いた肝胆膵領域の再生医療に関するimpactと課題2013

    • Author(s)
      池本哲也 島田光生, 宇都宮徹, 居村暁, 森根裕二, 森大樹, 荒川悠佑, 金本真美, 齋藤裕, 山田眞一郎, 淺野間理仁, 三宅秀則
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 高齢者の肝再生不全の機序解明と治療への応用2013

    • Author(s)
      荒川悠佑, 島田光生, 石川大地, 山田眞一郎, 淺野間理仁, 齋藤裕, 岩橋衆一, 金本真美, 森大樹, 池本哲也, 森根裕二, 居村暁,
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Whey protein含有高機能流動食を用いた周術期栄養療法の有用性2013

    • Author(s)
      金本真美, 島田光生, 宇都宮徹, 佐藤宏彦, 森根裕二, 居村暁, 池本哲也, 森大樹, 岩橋衆一, 齋藤裕, 山田眞一郎, 淺野間理仁,
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      マリンメッセ福岡(福岡県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Bevacizumabの小胞体ストレス応答を介した肝切除後肝機能障害改善・肝再生促進効果2013

    • Author(s)
      矢田圭吾, 島田光生, 宇都宮徹, 石橋広樹, 佐藤宏彦, 居村暁, 森根裕二, 池本哲也, 森大樹, 荒川悠佑, 金本真美,
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      マリンメッセ福岡(福岡県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 高齢ドナー肝再生不全と加齢指標マーカーについての検討2013

    • Author(s)
      荒川悠佑, 島田光生, 石川大地, 山田眞一郎, 淺野間理仁, 齋藤裕, 岩橋衆一, 金本真美, 池本哲也, 森根裕二, 居村暁, 宇都宮徹
    • Organizer
      第31回日本肝移植研究会
    • Place of Presentation
      熊本全日空ホテルニュースカイ(熊本県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ラットsmall-for-size graft modelにおける脾臓内遺伝子発現の変化Ingenuity Pathway Analysisを用いた検討2013

    • Author(s)
      荒川悠佑, 島田光生, 石川大地, 山田眞一郎, 齋藤裕, 髙須千絵, 岩橋衆一, 金本真美, 池本哲也, 居村暁, 森根裕二, 宇都宮徹
    • Organizer
      第49回日本移植学会総会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ヒト脂肪由来幹細胞による肝傷害軽減効果に関する基礎的検討2013

    • Author(s)
      齋藤裕, 島田光生, 宇都宮徹, 池本哲也, 山田眞一郎, 石川大地, 岩橋衆一, 金本真美, 荒川悠佑, 森大樹, 森根裕二, 居村暁
    • Organizer
      第49回日本移植学会総会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 脂肪由来幹細胞の傷害肝へのホーミング効果 -癌幹細胞転移メカニズムへの応用-2013

    • Author(s)
      齋藤裕, 島田光生, 宇都宮徹, 池本哲也, 山田眞一郎, 森根裕二, 居村暁, 森大樹, 荒川悠佑, 金本真美, 岩橋衆一, 髙須千絵,
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 高齢者に対する肝切除術後の肝再生不全の機序解明とその対策2013

    • Author(s)
      宇都宮 徹 他
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      城山観光ホテル(鹿児島)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Enkhbold Chinbold. One-Stop Shopping for 3-Dimensional Anatomy of Hepatic V asculature and Bile Duct with a Special Reference to Biliary Image Reconstruction2012

    • Author(s)
      Shimada M, Utsunomiya T , Imura S, Morine Y, Ikemoto T, Hanaoka J, Miyatani T , Saito Y , Yamada S
    • Organizer
      American College Of Surgeons Annual Clinical Congress (ACS2012)
    • Place of Presentation
      アメリカ(McCormick Place)
    • Related Report
      2013 Final Research Report
  • [Presentation] Impact of human adipose tissue derived regenerative cell for cryopreserved porcine islets2012

    • Author(s)
      Ikemoto T, Shimada M, Utsunomiya T, Imura S, Morine Y, Hanaoka J, Miyatani T , Kanamoto M
    • Organizer
      10 th World Congress of the International Hepato-Pancreato-Biliary Association (IHPBA2012)
    • Place of Presentation
      フランス (Paris des Congres)
    • Related Report
      2013 Final Research Report
  • [Presentation] ヒト脂肪由来幹細胞を用いた障害臓器修復に関する研究2012

    • Author(s)
      池本 哲也 他
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      幕張メッセ(千葉)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ヒト脂肪由来幹細胞の傷害肝へのhoming効果に関する研究2012

    • Author(s)
      斎藤 裕 他
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      幕張メッセ(千葉)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ヒト脂肪由来幹細胞による肝傷害軽減効果に関する基礎的検討2012

    • Author(s)
      斎藤 裕 他
    • Organizer
      第98回日本消化器病学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ヒト脂肪由来幹細胞はVEGFシグナルとは異なる経路で肝細胞傷害を軽減する2012

    • Author(s)
      浅野間 理仁 他
    • Organizer
      第27回日本Shock学会総会
    • Place of Presentation
      砂防会館(東京)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 高齢者ドナー肝に関する基礎的検討:肝再生及び肝障害に関して2012

    • Author(s)
      岩橋 衆一 他
    • Organizer
      第30回日本肝移植研究会
    • Place of Presentation
      ホテル日航福岡(福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 80歳以上超高齢者における肝切除、膵頭十二指腸切除の妥当性に関する検討2012

    • Author(s)
      山田 眞一郎 他
    • Organizer
      第74回日本臨床外科学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Bevacizumab ameliorates sinusoidal injury after oxaliplatin-based chemotherapy and enhances liver regeneration after hepatectomy2011

    • Author(s)
      Hanaoka J, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Mori H, Saito Y , Y amada S, Asanoma M
    • Organizer
      World Congress of the International Association of surgeons, Gastroenterologists and Oncologists(IASGO2011)
    • Place of Presentation
      京都(京王プラザホテル)
    • Related Report
      2013 Final Research Report
  • [Presentation] Cytoprotective effect of human adipose tissue derived stem cell on porcine islet cells2011

    • Author(s)
      Yamada S, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Mori H, Hanaoka J, Kanamoto M, Iwahashi S, Saito Y , Asanoma M
    • Organizer
      12th Congress of the Asian Society of Transplantation (CAST2011)
    • Place of Presentation
      韓国 (COEX)
    • Related Report
      2013 Final Research Report
  • [Presentation] The possibility of adipose-derived stem cells for an alternative therapy for liver failure2011

    • Author(s)
      Saito Y , Shimada M, Utsunomiya T, Ikemoto T, Yamada S, Morine Y, Imura S, Mori H, Hanaoka J, Sugimoto K, Asanoma M
    • Organizer
      12th Congress of the Asian Society of Transplantation (CAST2011)
    • Place of Presentation
      韓国 (COEX)
    • Related Report
      2013 Final Research Report
  • [Presentation] Ischemia reperfusion injury enhances SDF1 expressions and homing of adipose derived regenerative cells in the liver2011

    • Author(s)
      Saito Y , Shimada M, Utsunomiya T , Morine Y, Imura S, Ikemoto T, Mori H, Hanaoka J, Sugimoto K, Y amada S, Asanoma M
    • Organizer
      8th International Smposium on Minimal Residual Cancer (ISMRC2011)
    • Place of Presentation
      大阪府(Grand Cube Osaka)
    • Related Report
      2013 Final Research Report
  • [Presentation] Regeneration of caudate lobe in extended left lobe graft including caudate lobe after living donor liver transplantation2011

    • Author(s)
      Shimada M, Imura S, Mori H, Morine Y, Ikemoto T, Hanaoka J, Kanamoto M, Iwahashi S, Saito Y , Asanoma M, Y amada S, Utsunomiya T
    • Organizer
      European Society for Organ Transplantation (ESOT2011)
    • Place of Presentation
      イギリス (SECC)
    • Related Report
      2013 Final Research Report
  • [Presentation] The possibility of adipose-derived regenerative cells for an alternative therapy for liver failure2011

    • Author(s)
      Mori H, Shimada M, Saito Y , Utsunomiya T , Imura S, Morine Y , Ikemoto T , Hanaoka J, Iwahashi S, Asanoma M, Y amada S
    • Organizer
      European Society for Organ Transplantation (ESOT2011)
    • Place of Presentation
      イギリス (SECC)
    • Related Report
      2013 Final Research Report
  • [Presentation] Whey protein isolate, MEIN[〇!R], can reduce liver damege early after living donor liver transplantation2011

    • Author(s)
      Ishikawa D, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Mori H, Hanaoka J, Kanamoto M, Iwahashi S, Saito Y , Asanoma M, Kume H, Sasaki H
    • Organizer
      European Society for Organ Transplantation (ESOT2011)
    • Place of Presentation
      イギリス (SECC)
    • Related Report
      2013 Final Research Report
  • [Presentation] Green T ea Catechins Improve Liver Dysfunction Following Massive Hepatectomy Through Anti-Oxidative and Anti-Inflammatory Activities in Rat2011

    • Author(s)
      Saito Y , Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T, Mori H, Hanaoka J, Kanamoto M
    • Organizer
      Digestive Disease Week (DDW2011)
    • Place of Presentation
      アメリカ (McCormick Place)
    • Related Report
      2013 Final Research Report
  • [Presentation] ヒト脂肪由来幹細胞による肝再生療法に関する基礎的検討2011

    • Author(s)
      斎藤裕
    • Organizer
      第23回日本肝胆膵外科学会・学術集会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒト脂肪由来幹細胞による肝障害軽減効果に関する基礎的検討2011

    • Author(s)
      斎藤裕
    • Organizer
      第29回日本ヒト細胞学会学術集会
    • Place of Presentation
      パレブラン高志会館(富山県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Ischemia reperfusion injury enhances SDF1 expressions and homing of adipose derived regenerative cells in the liver2011

    • Author(s)
      Yu Saito
    • Organizer
      8th International Symposium on Minimal Residual Cancer (ISMRC2011)
    • Place of Presentation
      大阪インターナショナルコンベンションセンター(大阪府)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肝虚血再灌流傷害におけるヒト脂肪由来幹細胞homing effectの機序解明2011

    • Author(s)
      斎藤裕
    • Organizer
      19th TDDW 2011
    • Place of Presentation
      福岡国際センター(福岡県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肝虚血再灌流傷害におけるヒト脂肪由来幹細胞homing effectの機序解明2011

    • Author(s)
      斎藤裕
    • Organizer
      19th JDDW 2011
    • Place of Presentation
      福岡国際センター(福岡県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肝虚血再灌流傷害におけるヒト脂肪由来幹細胞ホーミング効果の機序解明2011

    • Author(s)
      斎藤裕
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      愛知県がんセンター(名古屋市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒト脂肪由来幹細胞による肝虚血再灌流障害軽減効果に関する基礎的検討2011

    • Author(s)
      斎藤裕
    • Organizer
      第47回日本移植学会総会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Related Report
      2011 Annual Research Report

URL: 

Published: 2011-04-06   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi