A population-based cohort study of spinal diseases using MRI
Project/Area Number |
23390357
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Orthopaedic surgery
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Research Institution | The University of Tokyo |
Principal Investigator |
AKUNE Toru 東京大学, 医学部附属病院, 准教授 (60282662)
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Co-Investigator(Kenkyū-buntansha) |
MURAKI Shigeyuki 東京大学, 医学部附属病院, 特任助教 (40401070)
OKA Hiroyuki 東京大学, 医学部附属病院, 特任助教 (60401064)
YOSHIMURA Noriko 東京大学, 医学部附属病院, 特任准教授 (60240355)
|
Project Period (FY) |
2011-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2013: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2011: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
|
Keywords | 脊椎疾患 / 疫学 / MRI / コホート研究 / コホート |
Research Abstract |
This study was investigated to elucidate epidemiologic evidence of spinal diseases using MRI in population-based cohorts of Japanese men and women. 1,011 participants (335 men and 676 women, mean 66.3 years) were enrolled. Participants completed an interviewer-administered questionnaire and underwent anthropometric measurements and assessments of physical performance. Radiograph and MRI of cervical, thoracic and lumbar spine were examined. Among 1,011 participants, those who had MRI-sensitive implanted devices and other disqualifiers were excluded. Prevalence of cervical spinal cord compression on MRI was 24.4% and that of lumbar spinal stenosis was 9.3% in the study population. Based on these data, 14.7 million were estimated to have cervical spinal cord compression and 5.8 million were estimated to have lumbar spinal stenosis in Japan.
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Report
(4 results)
Research Products
(90 results)
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[Journal Article] Prevalence and progression of radiographic ossification of the posterior longitudinal ligament and associated factors in the Japanese population : a 3-year follow-up of the ROAD study2014
Author(s)
Yoshimura N, Nagata K, Muraki S, Oka H, Yoshida M, Enyo Y, Kagotani R, Hashizume H, Yamada H, Ishimoto Y, Teraguchi M, Tanaka S, Kawaguchi H, Toyama Y, Nakamura K, Akune T
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Journal Title
Osteoporos Int
Volume: 25
Pages: 1089-98
Related Report
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[Journal Article] Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort : the Wakayama Spine Study2014
Author(s)
Teraguchi M, Yoshimura N, Hashizume H, Muraki S, Yamada H, Minamide A, Oka H, Ishimoto Y, Nagata K, Kagotani R, Takiguchi N, Akune T, Kawaguchi H, Nakamura K, Yoshida M
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Journal Title
Osteoarthritis Cartilage
Volume: 22
Pages: 104-10
Related Report
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[Journal Article] Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study.2014
Author(s)
Teraguchi M, Yoshimura N, Hashizume H, Muraki S, Yamada H, Minamide A, Oka H, Ishimoto Y, Nagata K, Kagotani R, Takiguchi N, Akune T, Kawaguchi H, Nakamura K, Yoshida M
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Journal Title
Osteoarthritis Cartilage
Volume: 22
Issue: 1
Pages: 104-110
DOI
Related Report
Peer Reviewed
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[Journal Article] Prevalence and progression of the radiographic ossification of posterior longitudinal ligament and its associated factors in the Japanese populations: A 3-year follow-up of the ROAD study.2014
Author(s)
Yoshimura N, Nagata K, Muraki S, Oka H, Yoshida M, Enyo Y, Kagotani R, Hashizume H, Yamada H, Ishimoto Y, Teraguchi M, Tanaka S, Kawaguchi H, Toyama Y, Nakamura K, Akune T
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Journal Title
Osteoporos Int
Volume: 25
Issue: 3
Pages: 1089-1098
DOI
Related Report
Peer Reviewed
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[Journal Article] Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) of the whole spine and its association with lumbar spondylosis and knee osteoarthritis: the ROAD study.2014
Author(s)
Kagotani R, Yoshida M, Muraki S, Oka H, Hashizume H, Yamada H, Enyo Y, Nagata K, Ishimoto Y, Teraguchi M, Tanaka S, Nakamura K, Kawaguchi H, Akune T, Yoshimura N.
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Journal Title
J Bone Miner Metab
Volume: 印刷中
Related Report
Peer Reviewed
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[Journal Article] Prevalence of knee pain, lumbar pain and its coexistence in Japanese men and women: The Longitudinal Cohorts of Motor System Organ (LOCOMO) study.2014
Author(s)
Yoshimura N, Akune T, Fujiwara S, Shimizu Y, Yoshida H, Omori G, Sudo A, Nishiwaki Y, Yoshida M, Shimokata H, Suzuki T, Muraki S, Oka H, Nakamura K.
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Journal Title
J Bone Miner Metab
Volume: 印刷中
Related Report
Peer Reviewed
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[Journal Article] Association of knee osteoarthritis with onset and resolution of pain and physical functional disability: The ROAD study.2014
Author(s)
Muraki S, Akune T, Nagata K, Ishimoto Y, Yoshida M, Tokimura F, Tanaka S, Oka H, Kawaguchi H, Nakamura K, Yoshimura N.
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Journal Title
Mod Rheumatol
Volume: 印刷中
Related Report
Peer Reviewed
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[Journal Article] Associations between radiographic lumbar spinal stenosis and clinical symptoms in the general population : the Wakayama Spine Study2013
Author(s)
Ishimoto Y, Yoshimura N, Muraki S, Yamada H, Nagata K, Hashizume H, Takiguchi N, Minamide A, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
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Journal Title
Osteoarthritis Cartilage
Volume: 21
Pages: 783-8
Related Report
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[Journal Article] Profiles of vitamin D insufficiency and deficiency in Japanese men and women: association with biological, environmental, and nutritional factors and coexisting disorders: the ROAD study.2013
Author(s)
Yoshimura N, Muraki S, Oka H, Morita M, Yamada H, Tanaka S, Kawaguchi H, Nakamura K, Akune T
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Journal Title
Osteoporos Int
Volume: 24
Issue: 11
Pages: 2775-2787
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Prevalence of vertebral fracture in Asian men and women : Comparison between Hong Kong, Thailand, Indonesia and Japan2012
Author(s)
Kwok AW, Leung JC, Chan AY, Au BS, Lau EM, Yurianto H, Yuktanandana P, Yoshimura N, Muraki S, Oka H, Akune T, Leung PC
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Journal Title
Public Health
Volume: 126
Pages: 523-531
Related Report
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[Journal Article] Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan : the Wakayama Spine Study2012
Author(s)
Ishimoto Y, Yoshimura N, Muraki S, Yamada H, Nagata K, Hashizume H, Takiguchi N, Minamide A, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
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Journal Title
Osteoarthritis Cartilage
Volume: 20
Pages: 1103-1108
Related Report
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[Journal Article] Prevalence of cervical cord compression and its association with physical performance in a population-based cohort in Japan : the Wakayama spine study2012
Author(s)
Nagata K, Yoshimura N, Muraki S, Hashizume H, Ishimoto Y, Yamada H, Takiguchi N, Nakagawa Y, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
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Journal Title
Spine (Phila Pa 1976)
Volume: 37
Pages: 1892-1898
NAID
Related Report
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[Journal Article] Physical performance, bone and joint diseases, and incidence of falls in Japanese men and women2012
Author(s)
Muraki S, Akune T, Oka H, Ishimoto Y, Nagata K, Yoshida M, Tokimura F, Nakamura K, Kawaguchi H, Yoshimura N
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Journal Title
A longitudinal cohort study. Osteoporosis Int (inpress)
Volume: 21(Epub ahead of print)
Issue: 2
Pages: 459-466
DOI
Related Report
Peer Reviewed
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[Journal Article] Health-related quality of life in subjects with low back pain and knee pain in a population-based cohort study of Japanese men : the ROAD study2011
Author(s)
Muraki S, Akune T, Oka H, Enyo Y, Yoshida M, Saika A, Suzuki T, Yoshida H, Ishibashi H, Tokimura F, Yamamoto S, Nakamura K, Kawaguchi H, Yoshimura N
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Journal Title
Spine (Phila Pa 1976)
Volume: 36
Pages: 1312-1319
Related Report
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[Journal Article] Reference values for hand grip strength, muscle mass, walking time, and one-leg standing time as indices for locomotive syndrome and associated disability : The second survey of the ROAD study2011
Author(s)
Yoshimura N, Oka H, Muraki S, Akune T, Hirabayashi N, Matsuda S, Nojiri T, Hatanaka K, Ishimoto Y, Nagata K, Yoshida M, Tokimura F, Kawaguchi H, Nakamura K
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Journal Title
J Orthop Sci
Volume: 16
Pages: 768-777
Related Report
Peer Reviewed
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[Journal Article] Independent association of joint space narrowing and osteophyte formation at the knee with health-related quality of life in Japan : A cross-sectional study2011
Author(s)
Muraki S, Oka H, Akune T, EnYo Y, Yoshida M, Suzuki T, Yoshida H, Ishibashi H, Tokimura F, Yamamoto S, Nakamura K, Kawaguchi H, Yoshimura N
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Journal Title
Arthritis Rheum
Volume: 63
Pages: 3859-3864
Related Report
Peer Reviewed
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[Journal Article] Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) of the whole spine and its association with lumbar spondylosis and knee osteoarthritis : the ROAD study
Author(s)
Kagotani R, Yoshida M, Muraki S, Oka H, Hashizume H, Yamada H, Enyo Y, Nagata K, Ishimoto Y, Teraguchi M, Tanaka S, Nakamura K, Kawaguchi H, Akune T, Yoshimura N
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Journal Title
J Bone Miner Metab
Volume: (in press)
Related Report
-
-
[Journal Article] Prevalence of knee pain, lumbar pain and its co-existence in Japanese men and women : The LOCOMO (Longitudinal Cohorts of Motor System Organ) study
Author(s)
Yoshimura N, Akune T, Fujiwara S, Shimizu Y, Yoshida H, Omori G, Sudo A, Nishiwaki Y, Yoshida M, Shimokata H, Suzuki T, Muraki S, Oka H, Nakamura K
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Journal Title
J Bone Miner Metab
Volume: (in press)
Related Report
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[Presentation] Association of diffuse idiopathic skeletal hyperostosis and bone mineral density and marker of bone metabolism : the ROAD study2013
Author(s)
Kagotani R, Muraki S, Oka H, Yoshida M, Hashizume H, Yamada H, Nagata K, Ishimoto Y, Teraguchi M, Tanaka S, Nakamura K, Kawaguchi H, Akune T, Yoshimura N
Organizer
IOF-ESCEO European Congress on Osteoporosis and Osteoarthritis
Place of Presentation
Rome, Italy
Related Report
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[Presentation] 大規模住民コホートにおける頸髄圧迫, 腰部脊柱管狭窄症と歩行機能, 体幹バランスとの関係2013
Author(s)
長田圭司, 吉村典子, 橋爪洋, 石元優々, 山田宏, 瀧口登, 南出晃人, 中川幸洋, 村木重之, 岡敬之, 阿久根徹, 吉田宗人
Organizer
第42回日本脊椎脊髄病学会
Place of Presentation
宜野湾市
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[Presentation] 全脊柱MRIを用いた大規模住民コホートにおける頸髄圧迫と腰部脊柱管狭窄の合併頻度2013
Author(s)
長田圭司, 吉村典子, 橋爪洋, 石元優々, 山田宏, 瀧口登, 南出晃人, 中川幸洋, 村木重之, 岡敬之, 阿久根徹, 吉田宗人
Organizer
第42回日本脊椎脊髄病学会
Place of Presentation
宜野湾市
Related Report
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[Presentation] 大規模住民コホートにおける頸髄圧迫, 腰部脊柱管狭窄症と歩行機能, 体幹バランスとの関係2013
Author(s)
長田圭司, 橋爪洋, 石元優々, 山田宏, 南出晃人, 中川幸洋, 村木重之, 岡敬之, 阿久根徹, 吉村典子, 吉田宗人
Organizer
第86回日本整形外科学会学術総会
Place of Presentation
広島市
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[Presentation] 頸椎MRIを用いた大規模住民コホートにおける頸髄症の関連因子2013
Author(s)
長田圭司, 橋爪洋, 石元優々, 山田宏, 南出晃人, 中川幸洋, 村木重之, 岡敬之, 阿久根徹, 吉村典子, 吉田宗人
Organizer
第86回日本整形外科学会学術総会
Place of Presentation
広島市
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[Presentation] 腰部脊柱管狭窄症と骨粗鬆症の合併は腰痛, QOL と関連するか-一般住民コホートを用いた横断的研究2013
Author(s)
橋爪洋, 吉村典子, 石元優々, 山田宏, 長田圭司, 岡敬之, 村木重之, 阿久根徹, 瀧口登, 吉田宗人
Organizer
第86回日本整形外科学会学術総会
Place of Presentation
広島市
Related Report
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[Presentation] 頸椎脊柱管前後径の年代別評価 大規模一般住民コホートを用いた頸椎単純X 線の検討2012
Author(s)
長田圭司, 橋爪洋, 石元優々, 山田宏, 南出晃人, 中川幸洋, 河合将紀, 岩崎博, 木岡雅彦, 瀧口登, 村木重之, 岡敬之, 阿久根徹, 吉村典子, 吉田宗人
Organizer
第41回日本脊椎脊髄病学会
Place of Presentation
久留米
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[Presentation] 頸椎画像所見と頸髄圧迫との関連 大規模住民コホートを用いた検討2012
Author(s)
長田圭司, 橋爪洋, 石元優々, 山田宏, 南出晃人, 中川幸洋, 河合将紀, 岩崎博, 木岡雅彦, 瀧口登, 村木重之, 岡敬之, 阿久根徹, 吉村典子, 吉田宗人
Organizer
第41回日本脊椎脊髄病学会
Place of Presentation
久留米
Related Report
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[Presentation] Prevalence of cervical cord compression and its relations to physical signs and performances in a Japanese population-based cohort : The ROAD-MRI Study2011
Author(s)
Nagata K, Yoshida M, Hashizume H, Yamada H, Ishimoto Y, Takiguchi N, Muraki S, Oka H, Akune T, Yoshimura N
Organizer
The 8th Combined Congress of the Spine and Pediatric Sections, Asia Pacific Orthopaetic Association (APOA)
Place of Presentation
Gifu, Japan
Related Report
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[Presentation] The prevalence of lumbar spinal stenosis using MRI in a local cohort : The ROAD-MRI Study2011
Author(s)
Ishimoto Y, Yamada H, Hashizume H, Nagata K, Takiguchi N, Yoshida M, Muraki S, Oka H, Akune T, Yoshimura N
Organizer
The 8th Combined Congress of the Spine and Pediatric Sections, Asia Pacific Orthopaetic Association (APOA)
Place of Presentation
Gifu, Japan
Related Report
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[Presentation] The Prevalence of the lumbar spinal stenosis with Mobile MRI in a population-based cohort : The ROAD-MRI Study2011
Author(s)
Ishimoto Y, Yoshida M, Yamada H, Nagata K, Hashizume H, Takiguchi N, Muraki S, Oka H, Akune T, Yoshimura N
Organizer
Annual Meeting of the International Society for the Study of the Lumbar Spine (ISSLS)
Place of Presentation
Gothenburg, Sweden
Related Report
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[Presentation] The Prevalence of the lumbar spinal stenosis with Mobile MRI in a population-based cohort : The Road-MRI Study2011
Author(s)
Ishimoto Y, Yoshida M, Yamada H, Nagata K, Hashizume H, Takiguchi N, Shigeyuki M, Oka H, Akune T, Yoshimura N
Organizer
Annual Meeting of the International Society for the Study of the Lumbar Spine (ISSLS)
Place of Presentation
Gothenburg, Sweden
Related Report
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