| Project/Area Number |
23390361
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Mie University |
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Principal Investigator |
SUDO Akihiro 三重大学, 医学(系)研究科(研究院), 教授 (60196904)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUMINE Akihiko 三重大学, 大学院・医学系研究科, 准教授 (00335118)
NISHIMURA Akinobu 三重大学, 大学院・医学系研究科, 講師 (10508526)
AKEDA Koji 三重大学, 医学部附属病院, 講師 (20422826)
HASEGAWA Masahiro 三重大学, 医学部附属病院, 講師 (40308664)
WAKABAYASHI Hiroki 三重大学, 医学部附属病院, 講師 (50362687)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2013: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2012: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2011: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Keywords | コホート研究 / 運動器不安定 / ロコモティブシンドローム / 要介護認定 / ロコモ25 / 骨粗鬆症 / 変形性膝関節症 / 椎体骨折 / 疫学調査 / 遺伝子 / 変形性脊椎症 / 運動器不安定症 / 住民検診 |
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| Research Abstract |
Japanese society is rapidly aging. Therefore, it is very important to prevent elderly locomotive diseases such as osteoporosis (OP), vertebral fractures (VF), and knee osteoarthritis (KOA). We examined elderly inhabitants of Miyagawa Village every 2 years since 1997 for OP, VF, KOA and their physical function. Our results show KOA and VF are related to a decrease in their physical function. Also, the mortality rate was worse for elderly individuals with both OP and VF than those with any other combination of OP and VF. Prevention of KOA and VF is useful to maintain the physical activity of elderly people, and prevention of osteoporotic VF in elderly persons may increase life expectancy.
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