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Development of high accuracy deformity correction system for the limb

Research Project

Project/Area Number 23390362
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionOsaka University

Principal Investigator

MURASE TSUYOSHI  大阪大学, 医学(系)研究科(研究院), 准教授 (50335361)

Co-Investigator(Kenkyū-buntansha) MORITOMO Hisao  大阪行岡医療大学, 医療学部理学療法学科, 教授 (00332742)
SAKAI Takashi  大阪大学, 医学系研究科, 講師 (00444539)
SUGAMOTO Kazuomi  大阪大学, 医学系研究科, 寄附講座教授 (40294061)
YOSHIKAWA Hideki  大阪大学, 医学系研究科, 教授 (60191558)
Project Period (FY) 2011-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2014: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Keywords変形矯正 / 手術シミュレーション / 矯正骨切術 / 手術ガイド / コンピュータシミュレーション / 整形外科 / 四肢変形 / シミュレーション / 手術デバイス / 矯正
Outline of Final Research Achievements

Highly accurate technique of deformity correction for the limb was yet to be established. We aimed to develop a system for deformity correction that substantially exceeds conventional methods in terms of accuracy, using CT data, advanced software technology and rapid prototyping. At the end stage of the project, we completed a total compute simulation software that enabled construction of virtual bone models from CT data and plan a most appropriate deformity correction. A custom-made plastic device was also developed based on the computer simulation. Verification test using fresh cadaver specimen that was conducted with use of custom-made devices designed based on preoperative computer planning revealed that the error was within 2 mm and 1.5 degrees. The preliminary clinical trial that was targeted cubitus varus deformity showed favorable results with the errors 0.6 +-0.7° in varus-valgus direction, 0.8 ±1.3° in extension-flexion direction and 2.9 ±2.8° in rotational direction.

Report

(5 results)
  • 2015 Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (52 results)

All 2015 2014 2013 2012 2011 Other

All Journal Article (24 results) (of which Peer Reviewed: 24 results) Presentation (25 results) (of which Int'l Joint Research: 3 results,  Invited: 12 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Postoperative accuracy analysis of three-dimensional corrective osteotomy for cubitus varus deformity with a custom-made surgical guide based on computer simulation.2015

    • Author(s)
      Omori S, Murase T, Oka K, Kawanishi Y, Oura K, Tanaka H, Yoshikawa H.
    • Journal Title

      J Shoulder Elbow Surg

      Volume: 24 Issue: 2 Pages: 242-9

    • DOI

      10.1016/j.jse.2014.08.020

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo 3-dimensional analysis of stage III Kienbock disease: pattern of carpal deformity and radioscaphoid joint congruity2015

    • Author(s)
      Kawanishi Y, Moritomo H, Omokawa S, Murase T, Sugamoto K, Yoshikawa H.
    • Journal Title

      J Hand Surg Am

      Volume: 40 Issue: 1 Pages: 74-80

    • DOI

      10.1016/j.jhsa.2014.10.035

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional corrective osteotomy using a patient-specific osteotomy guide and bone plate based on a computer simulation system: accuracy analysis in a cadaver study2014

    • Author(s)
      Omori S, Murase T, Kataoka T, Kawanishi Y, Oura K, Miyake J, Tanaka H, Yoshikawa H.
    • Journal Title

      Int J Med Robot

      Volume: 10 Issue: 2 Pages: 196-202

    • DOI

      10.1002/rcs.1530

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional corrective osteotomy for cubitus varus deformity with use of custom-made surgical guides2014

    • Author(s)
      Murase T, Takeyasu Y, Oka K, Kataoka T, Tanaka H, H Yoshikawa.
    • Journal Title

      JBJS Essential Surgical Technique

      Volume: 4 Pages: 1-7

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Arthroscopic debridement in the treatment of patients with osteoarthritis of the elbow, based on computer simulation2014

    • Author(s)
      Miyake J, Shimada K, Oka K, Tanaka H, Sugamoto K, Yoshikawa H, Murase T.
    • Journal Title

      Bone Joint J

      Volume: 96-b Issue: 2 Pages: 237-41

    • DOI

      10.1302/0301-620x.96b2.30714

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Kinematic changes in elbow osteoarthritis: in vivo and 3-dimensional analysis using computed tomographic data.2013

    • Author(s)
      Miyake J, Shimada K, Moritomo H, Kataoka T, Murase T, Sugamoto K.
    • Journal Title

      J Hand Surg Am

      Volume: 38 Pages: 957-964

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Does cubitus varus cause morphologic and alignment changes in the elbow joint?2013

    • Author(s)
      Kawanishi Y, Miyake J, Kataoka T, Omori S, Sugamoto K, Yoshikawa H, Murase T.
    • Journal Title

      J Shoulder Elbow Surg

      Volume: 22 Pages: 915-923

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 3-Dimensional prebent plate fixation in corrective osteotomy of malunited upper extremity fractures using a real-sized plastic bone model prepared by preoperative computer simulation.2013

    • Author(s)
      Kataoka T, Oka K, Miyake J, Omori S, Tanaka H, Murase T.
    • Journal Title

      J Hand Surg Am

      Volume: 38 Pages: 909-919

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 3-Dimensional deformity analysis of malunited forearm diaphyseal fractures.2013

    • Author(s)
      Miyake J, Oka K, Kataoka T, Moritomo H, Sugamoto K, Murase T.
    • Journal Title

      J Hand Surg Am

      Volume: 38 Pages: 1356-1365

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo 3-dimensional analysis of dorsal intercalated segment instability deformity secondary to scapholunate dissociation: a preliminary report.2013

    • Author(s)
      Omori S, Moritomo H, Omokawa S, Murase T, Sugamoto K, Yoshikawa H.
    • Journal Title

      J Hand Surg Am

      Volume: 38 Pages: 1346-1355

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preoperative, computer simulation-based, three-dimensional corrective osteotomy for cubitus varus deformity with use of a custom-designed surgical device.2013

    • Author(s)
      Takeyasu Y, Oka K, Miyake J, Kataoka T, Moritomo H, Murase T.
    • Journal Title

      J Bone Joint Surg Am

      Volume: 95

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional deformity analysis of malunited distal radius fractures and their influence on wrist and forearm motion.2012

    • Author(s)
      Miyake J, Murase T, Yamanaka Y, Moritomo H, Sugamoto K, Yoshikawa H.
    • Journal Title

      J Hand Surg Eur

      Volume: 37 Pages: 506-512

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional analysis of acute plastic bowing deformity of ulna in radial head dislocation or radial shaft fracture using a computerized simulation system.2012

    • Author(s)
      Kim E, Moritomo H, Murase T, Masatomi T, Miyake J, Sugamoto K.
    • Journal Title

      J Shoulder Elbow Surg

      Volume: 21 Pages: 1644-1650

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo three-dimensional motion analysis of chronic radial head dislocations.2012

    • Author(s)
      Miyake J, Moritomo H, Kataoka T, Murase T, Sugamoto K.
    • Journal Title

      Clin Orthop Relat Res

      Volume: 470 Pages: 2746-2755

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of three dimensional and radiographic measurements in the analysis of distal radius malunion.2012

    • Author(s)
      Miyake J, Murase T, Yamanaka Y, Moritomo H, Sugamoto K, Yoshikawa H.
    • Journal Title

      J Hand Surg Eur

      Volume: 38 Pages: 133-143

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Corrective osteotomy for malunited both bones fractures of the forearm with radial head dislocations using a custom-made surgical guide: two case reports.2012

    • Author(s)
      Oka K, Murase T, Moritomo H, Yoshikawa H.
    • Journal Title

      J Shoulder Elbow Surg

      Volume: 21

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional motion of the uncovertebral joint during head rotation.2012

    • Author(s)
      Nagamoto Y, Ishii T, Iwasaki M, Sakaura H, Moritomo H, Fujimori T, Kashii M, Murase T, Yoshikawa H, Sugamoto K.
    • Journal Title

      J Neurosurg Spine

      Volume: 17 Pages: 327-333

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Computer-assisted corrective osteotomy for malunited diaphyseal forearm fractures.2012

    • Author(s)
      Miyake J, Murase T, Oka K, Moritomo H, Sugamoto K, Yoshikawa H.
    • Journal Title

      J Bone Joint Surg Am

      Volume: 94

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Validation of the femoral component placement during hip resurfacing: a comparison between the conventional jig, patient-specific template, and CT-based navigation.2012

    • Author(s)
      Kitada M, Sakai T, Murase T, Hanada T, Nakamura N, Sugano N.
    • Journal Title

      Int J Med Robot

      Volume: 9 Pages: 223-229

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Corrective osteotomy and ligament repair for longstanding radial collateral ligament tear of the proximal interphalangeal joint: case series.2012

    • Author(s)
      Miyake J
    • Journal Title

      J Hand Surg Am

      Volume: 37 Pages: 440-445

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional analysis of cubitus varus deformity after supracondylar fractures of the humerus.2011

    • Author(s)
      Takayesu Y
    • Journal Title

      J Shoulder Elbow Surg

      Volume: 20 Pages: 440-448

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in shape and length of the collateral and accessory collateral ligaments of the metacarpophalangeal joint during flexion.2011

    • Author(s)
      Kataoka T
    • Journal Title

      J Bone Joint Surg Am

      Volume: 93 Pages: 1318-1325

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo and 3-dimensional functional anatomy of the anterior bundle of the medial collateral ligament of the elbow.2011

    • Author(s)
      Miyake J
    • Journal Title

      J Shoulder Elbow Surg

      Volume: 21 Pages: 1006-1012

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Open reduction and 3-dimensional ulnar osteotomy for chronic radial head dislocation using a computer-generated template: case report.2011

    • Author(s)
      Miyake J
    • Journal Title

      J Hand Surg Am

      Volume: 37 Pages: 517-22

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 上肢変形矯正の3Dシミュレーション手術2015

    • Author(s)
      Tsuyoshi Murase
    • Organizer
      第28回日本創外固定・骨延長学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-03-20
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Patient Matched Instrument in Hand and Upper Extremity Surgery2014

    • Author(s)
      Tsuyoshi Murase
    • Organizer
      Peking University International Symposium on the application of 3D-printing in Orthopaedics
    • Place of Presentation
      Beijing, China
    • Year and Date
      2014-12-13
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 3D corrective osteotomy of malunited upper extremity fracutres2014

    • Author(s)
      Tsuyoshi Murase
    • Organizer
      10th APFSSH
    • Place of Presentation
      Kuala Lumpr, Malaysia
    • Year and Date
      2014-10-01
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Patient Matched Instrument in Hand Surgery2014

    • Author(s)
      Murase Tsuyoshi
    • Organizer
      International Symposium on the Applications of 3D Printing (Rapid Prototyping) in Orthopaedics
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2014-09-20
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 三次元シミュレーション技術を応用した患者適合型上肢変形矯正術2014

    • Author(s)
      村瀬 剛
    • Organizer
      第57回日本手外科学会学術集会
    • Place of Presentation
      宜野湾
    • Year and Date
      2014-04-17
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 未来への扉 -手- 3Dが変える近未来の手外科2013

    • Author(s)
      村瀬 剛
    • Organizer
      第86回 日本整形外科学会学術総会
    • Place of Presentation
      リーガロイヤルホテル広島(広島市)
    • Year and Date
      2013-05-23 – 2013-05-26
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] コンピューターシミュレーションに基づき術前プレベンディングしたプレートを用いた上肢骨変形治癒に対する三次元矯正骨切り術2013

    • Author(s)
      片岡利行、村瀬 剛、大浦圭一郎、川西洋平、大森信介、三宅 潤一、田中 啓之
    • Organizer
      第86回 日本整形外科学会学術総会
    • Place of Presentation
      リーガロイヤルホテル広島(広島市)
    • Year and Date
      2013-05-23 – 2013-05-26
    • Related Report
      2013 Annual Research Report
  • [Presentation] 術前三次元動作解析シミュレーションに基づいた変形性関節症に対する鏡視下関節形成2013

    • Author(s)
      三宅 潤一、島田 幸造、田中 啓之、森友寿夫、村瀬 剛、菅本一臣、吉川秀樹
    • Organizer
      第86回 日本整形外科学会学術総会
    • Place of Presentation
      リーガロイヤルホテル広島(広島市)
    • Year and Date
      2013-05-23 – 2013-05-26
    • Related Report
      2013 Annual Research Report
  • [Presentation] 3 次元変形矯正骨切シミュレーションシステムにおけるカスタムメイドプレートの開発;新鮮屍体による精度検証2013

    • Author(s)
      大森 信介、片岡 利行, 大浦 圭一郎, 川西 洋平, 村瀬  剛
    • Organizer
      第56回 日本手外科学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2013-04-18 – 2013-04-19
    • Related Report
      2013 Annual Research Report
  • [Presentation] 3次元モデルを用いた舟状骨偽関節の病態解析と手術計画2013

    • Author(s)
      村瀬 剛、片岡 利行, 三宅 潤一, 田中 啓之, 森友 寿夫
    • Organizer
      第56回 日本手外科学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2013-04-18 – 2013-04-19
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] カスタムメイド骨切りガイドを用いた矯正骨切り術の実際2013

    • Author(s)
      村瀬 剛、三宅 潤一, 片岡 利行, 田中 啓之, 森友 寿夫
    • Organizer
      第56回 日本手外科学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2013-04-18 – 2013-04-19
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 上肢運動器障害における新世代三次元評価とその臨床応用2013

    • Author(s)
      村瀬 剛
    • Organizer
      第15回 鶴舞手外科セミナー
    • Place of Presentation
      名鉄ニューグランドホテル(名古屋市)
    • Year and Date
      2013-04-11
    • Related Report
      2013 Annual Research Report
  • [Presentation] 新鮮屍体標本を用いた三次元矯正骨切シミュレーションシステムにおける精度検証2012

    • Author(s)
      大森信介、村瀬 剛、片岡利行、川西洋平、三宅 潤一、森友 寿夫、菅本一臣、吉川 秀樹
    • Organizer
      第27回日本整形外科学会基礎学術集会
    • Place of Presentation
      福井
    • Related Report
      2012 Annual Research Report
  • [Presentation] 骨間膜病態と手術シミュレーション -陳旧性モンテジア脱臼骨折における3次元解析-2012

    • Author(s)
      村瀬 剛、三宅 潤一、岡 久仁洋、片岡利行、森友 寿夫
    • Organizer
      第55回日本手外科学会学術集会
    • Place of Presentation
      横浜
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 3Dカスタムメイド手術ガイドと掌側ロッキングプレートを用いた橈骨遠位端骨折変形治癒矯正骨切り術2012

    • Author(s)
      村瀬 剛、三宅 潤一、片岡利行、森友 寿夫、岡田 潔、岡 久仁洋、堀木充、菅本一臣、吉川 秀樹
    • Organizer
      第85回日本整形外科学会学術総会
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] IN VIVO 3-DIMENSIONAL EVALUATION OF ELBOW INSTABILITY OF NON-UNION OF THE LATERAL HUMERAL CONDYLE DURING FLEXION-EXTENSION MOTION: USING 3D IMAGES MATCHING TECHNIQUE2012

    • Author(s)
      Goto A
    • Organizer
      Orthopedic Research Society
    • Place of Presentation
      サンフランシスコ
    • Related Report
      2011 Annual Research Report
  • [Presentation] 3Dカスタムガイドを用いた関節リウマチ(RA)症例における人工足関節全置換術2011

    • Author(s)
      平尾眞
    • Organizer
      日本リウマチ学会・学術集会
    • Place of Presentation
      神戸
    • Related Report
      2011 Annual Research Report
  • [Presentation] 3D analysis of the elbow and forearm and its clinical application

    • Author(s)
      Tsuyoshi Murase
    • Organizer
      Honam shoulder & elbow symposium
    • Place of Presentation
      Kwangju, Korea (光州、韓国)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 変形矯正のパラダイムシフト

    • Author(s)
      村瀬 剛
    • Organizer
      第3回姫路骨・関節疾患研究会
    • Place of Presentation
      姫路
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 3次元シミュレーションに基づいた骨折後遺症治療 -小児肘関節周囲骨折を中心に-

    • Author(s)
      村瀬 剛
    • Organizer
      兵庫県骨折治療研究会
    • Place of Presentation
      神戸
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 3次元骨モデルを使用した人工肘関節術前計画

    • Author(s)
      二井 数馬
    • Organizer
      日本肘関節学会
    • Place of Presentation
      長岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] 上腕骨顆上骨折後内反肘における関節形態変化

    • Author(s)
      川西洋平
    • Organizer
      日本肘関節学会
    • Place of Presentation
      長岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] 成人内反肘に対する3次元シミュレーション矯正骨切り術

    • Author(s)
      村瀬 剛
    • Organizer
      日本肘関節学会
    • Place of Presentation
      長岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] 陳旧性Monttegia脱臼骨折に対する3次元解析

    • Author(s)
      三宅 潤一
    • Organizer
      日本肘関節学会
    • Place of Presentation
      長岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] 上腕骨顆上骨折後内反肘の自家矯正

    • Author(s)
      片岡利行
    • Organizer
      日本肘関節学会
    • Place of Presentation
      長岡
    • Related Report
      2011 Annual Research Report
  • [Book] Computer-Assisted Musculoskeletal Surgery. [Chapter 19. Computer Simulation Surgery for Deformity Correction of the Upper Extremity]2015

    • Author(s)
      Murase Tsuyohsi (Lucas E. Ritacco et al ed)
    • Total Pages
      326
    • Publisher
      Springer International Publishing
    • Related Report
      2014 Annual Research Report
  • [Book] 肘関節手術のすべて[ II肘関節疾患の治療 内反肘・外反肘]2015

    • Author(s)
      村瀬 剛(今谷潤也 編)
    • Total Pages
      407
    • Publisher
      メジカルビュー社
    • Related Report
      2014 Annual Research Report
  • [Remarks] 大阪大学整形外科 手の外科クリニック

    • URL

      http://www.ort.med.osaka-u.ac.jp/research8-3.html

    • Related Report
      2011 Annual Research Report

URL: 

Published: 2011-04-06   Modified: 2019-07-29  

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