| Project/Area Number |
23390394
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KISHIMOTO Seiji 東京医科歯科大学, 医歯(薬)学総合研究科, 教授 (30115828)
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| Co-Investigator(Kenkyū-buntansha) |
TSUNODA Atsunobu 東京医科歯科大学, 大学院・医歯学総合研究科, 准教授 (00280983)
SUGIMOTO Taro 東京医科歯科大学, 大学院・医歯学総合研究科, 講師 (60262177)
AKITA Keiichi 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (80231819)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
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| Keywords | 頭蓋底外科 / 手術アプローチ / 低侵襲手術 / 頭蓋底手術法 / 骨血流 / 耳管解剖 / 頭蓋底手術 / 頭蓋底解剖 / ICG蛍光測定法 / 骨弁血流 / 頭蓋底再建 |
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| Research Abstract |
In the case of craniofacial approach for extirpation of the skull base tumor, facial skin incision and splitting of the facial skeleton are required. Therefore, this operation is difficult and results in severe invasion. Furthermore, the postoperative cosmetic and functional morbidity is also remarkable. For these reasons, this skull base surgery does not become standardized. We studied the following two items for the purpose of establishment and standardization of the skull base surgery with less invasiveness and postoperative functional and cosmetic morbidity. Firstly, we developed the new surgical methods with less invasiveness by study of the dissection of the cadaver fixed using Thiel method. Secondly, we examined the technique of division of the facial skeleton and soft tissue by the method of indocyanine green fluorometry in order to preserve good blood flow.
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