| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2013: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
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| Research Abstract |
Sixty percent of adult in Japan have Japanese cedar pollen (JCP)-specific IgE. Prevalence of allergic rhinitis (AR) caused by JCP (AR-JCP) in Japanese adults is 40%. In this study we investigated AR-JCP-related gene by genome wide associated study, and gene expression by microarray and proteome analysis. We found that ORMDL-3, CST-1, IL-33, Allergin-1, and Apolipoprotein A4 are associated with onset of AR-JCP. Several SNP are also found to be associated with AR-JCP.
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