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Depth profiling XAFS analysis of the interface between surface treated implant and bone

Research Project

Project/Area Number 23390438
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionTokyo Medical and Dental University

Principal Investigator

UO Motohiro  東京医科歯科大学, 医歯(薬)学総合研究科, 教授 (20242042)

Co-Investigator(Kenkyū-buntansha) ASAKURA Kiyotaka  北海道大学, 触媒化学研究センター, 教授 (60175164)
YOKOYAMA Atsuro  北海道大学, 大学院歯学研究科, 教授 (20210627)
AIDA Hideki  北海道医療大学, 歯学部, 准教授 (10301011)
HONGO Toshio  東京医科歯科大学, 大学院医歯学総合研究科, 准教授 (60142444)
WADA Takahiro  東京医科歯科大学, 大学院医歯学総合研究科, 助教 (10632317)
亘理 文夫  北海道大学, 歯学研究科(研究院), 教授 (70158682)
Project Period (FY) 2011-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2011: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Keywordsインプラント / 表面処理 / 骨結合 / X線 / XAFS / チタン / 表面分析
Outline of Final Research Achievements

Biocompatibility of various dental and medical materials is affected by the  conditions of materials surface, interface and erosion of trace metallic elements from the metallic materials and their accumulation in the tissues. In this study, the accumulation of dental alloy elements in the mucosa closely contacted with the metallic restorations using the position sensitive elemental and chemical state analysis method with X-ray microbeam. In addition, the chemical state analysis of the surface layer of surface treated titanium implant and the depth dependent change of titanium oxide was suggested.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (31 results)

All 2015 2014 2013 2012 2011 Other

All Journal Article (11 results) (of which Peer Reviewed: 11 results,  Open Access: 3 results,  Acknowledgement Compliant: 5 results) Presentation (18 results) (of which Invited: 2 results) Book (2 results)

  • [Journal Article] Estimation of trace metal element containing oral mucosa specimens by using SR-XRF, PIXE, and XAFS2015

    • Author(s)
      Tomoko SUGIYAMA, Motohiro UO, Takahiro WADA, Daisuke OMAGARI, Kazuo KOMIYAMA, Tadahide NOGUCHI, Yoshinori JINBU, Mikio KUSAMA
    • Journal Title

      BioMetals

      Volume: 28 Issue: 1 Pages: 11-20

    • DOI

      10.1007/s10534-014-9796-6

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Detection of trace metallic elements in oral lichenoid contact lesions using SR-XRF, PIXE, and XAFS2015

    • Author(s)
      Sugiyama T, Uo M, Wada T, Omagari D, Komiyama K, Miyazaki S, Numako C, Noguchi T, Jinbu Y, Kusama M, Mori Y.
    • Journal Title

      Scientific Reports

      Volume: 未定

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Applications of X-ray fluorescence analysis (XRF) to dental and medical specimens.2015

    • Author(s)
      Uo M, Wada T, Sugiyama T
    • Journal Title

      Journal of Dental Science Review

      Volume: 51 Issue: 1 Pages: 2-9

    • DOI

      10.1016/j.jdsr.2014.07.001

    • NAID

      50009645829

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 放射光XRF およびXAFS を用いた 超硬合金肺病理標本中の元素分析2015

    • Author(s)
      宇尾基弘,和田敬広,杉山知子, 中野郁夫,木村清延,谷口菜津子,猪又崇志,今野 哲,西村正治
    • Journal Title

      X線分析の進歩

      Volume: 46 Pages: 177-186

    • NAID

      40020424796

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Novel metal allergy patch test using metal nanoballs2014

    • Author(s)
      Tomoko SUGIYAMA, Motohiro UO, Takahiro WADA, Toshio HONOGO, Daisuke OMAGARI, Kazuo KOMIYAMA, Hitoshi SASAKI, Heishichiro TAKAHASHI, Mikio KUSMA, Yoshiyuki MORI
    • Journal Title

      Journal of Nanobiotechnology

      Volume: 12 Issue: 1 Pages: 1-6

    • DOI

      10.1186/s12951-014-0051-7

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Applicability of bacterial cellulose as an alternative to paper points in endodontic treatment2013

    • Author(s)
      A. Yoshino, M. Tabuchi, M. Uo, H. Tatsumi, K. Hideshima, S. Kondo, J. Sekine
    • Journal Title

      Acta biomaterialia

      Volume: 9 Issue: 4 Pages: 6116-6122

    • DOI

      10.1016/j.actbio.2012.12.022

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rare earth oxide containing filler for dental composite resin2013

    • Author(s)
      Uo M., Nakajima Y., Asakawa Y., Wada T., Hongo T., Soga K., Kogo Y.
    • Journal Title

      Key Engineering Materials

      Volume: 529-530 Pages: 512-515

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effects of the coating of anodized titanium with multi-walled carbon nanotuves on bone formation2013

    • Author(s)
      Inoue S., Uo M., Sakairi M., Hirata E., Lee M.H., Bae T.S., Akasaka T., Watari F., Yokoyama A.
    • Journal Title

      Key Engineering Materials

      Volume: 529-530 Pages: 621-624

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effects of the coating of anodized titanium with multi-walled carbon nanotubes on bone foramation.2012

    • Author(s)
      Ioue S.
    • Journal Title

      Key Engineering Materials

      Volume: 529-530 Pages: 621-624

    • DOI

      10.4028/www.scientific.net/kem.529-530.621

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid and non-destructive analysis of metallic dental restorations using X-ray fluorescence spectra and light-element sampling tools2012

    • Author(s)
      Furuhashi K., Uo M., Kitagawa Y., Watari F.
    • Journal Title

      Applied Surface Science

      Volume: 262 Pages: 56-59

    • DOI

      10.1016/j.apsusc.2011.12.007

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phase transformation of zirconia ceramics by hydrothermal degradation2011

    • Author(s)
      Kawai Y, Uo M., Wang Y., Kono S., Ohnuki S., Watari F.
    • Journal Title

      Dental Materials Journal

      Volume: 30 Pages: 286-292

    • NAID

      10029136608

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] SR-XRF用フィルム状濃度標準試料の作製2015

    • Author(s)
      杉山知子,和田敬広,宇尾基弘,森 良之
    • Organizer
      第3回物構研サイエンスフェスタ
    • Place of Presentation
      エポカルつくば(つくば)
    • Year and Date
      2015-03-17 – 2015-03-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] 全反射蛍光X線分析による病理組織標本中の微量金属元素の検出2014

    • Author(s)
      宇尾基弘,杉山知子,和田敬広,永井宏樹,清水文雄
    • Organizer
      第50回X線分析討論会
    • Place of Presentation
      東北大学(仙台)
    • Year and Date
      2014-10-30 – 2014-10-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] 歯質へのストロンチウムの吸収状態のマイクロPIXEおよび蛍光XAFSによる評価2014

    • Author(s)
      宇尾基弘,杉山知子,和田敬広,及川将一,中村圭喜,中塚稔之,中元絢子,半場秀典,二階堂徹,田上順次
    • Organizer
      第30回PIXEシンポジウム
    • Place of Presentation
      岩手医科大学(盛岡)
    • Year and Date
      2014-10-22 – 2014-10-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] 金属ナノボールを用いた高信頼性の新規皮膚パッチテストの開発2014

    • Author(s)
      杉山知子,宇尾基弘,尾曲大輔,小宮山一雄,野口忠秀,神部芳則,草間幹夫,森良之
    • Organizer
      第59回日本口腔外科学会学術大会
    • Place of Presentation
      幕張メッセ(千葉)
    • Year and Date
      2014-10-20 – 2014-10-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 量子ビームを用いた口腔粘膜疾患組織に含まれる微量金属元素の評価に関する研究2014

    • Author(s)
      杉山知子,和田敬広,本郷敏雄,宇尾基弘
    • Organizer
      第64回日本歯科理工学会学術講演会
    • Place of Presentation
      アステールプラザ(広島)
    • Year and Date
      2014-10-04 – 2014-10-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] SR-XRF, PIXE及びXAFSを用いた口腔粘膜疾患組織中の微量金属元素の分布と状態分析2014

    • Author(s)
      杉山知子, 和田敬広, 宇尾基弘, 尾曲大輔, 小宮山一雄, 沼子千弥, 及川将一, 森良之
    • Organizer
      第17回XAFS討論会
    • Place of Presentation
      徳島大学(徳島)
    • Year and Date
      2014-09-01 – 2014-09-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] 各種歯科用合金からの溶出合金元素の分布および状態分析2014

    • Author(s)
      宇尾基弘,杉山知子,神部芳則,草間幹夫,尾曲大輔,小宮山一雄,高師則行,鄭 漢忠
    • Organizer
      第68回日本口腔科学会学術集会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-05-07 – 2014-05-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] Application of SR-XRF and XAFS for the trace element analysis contained in histopathological specimens2014

    • Author(s)
      M. Uo, T. Wada, T. Sugiyama, M. Kusama, D. Omagari, K. Komiyama, N. Taniguchi, T. Inomata, S. Konno, M. Nishimura
    • Organizer
      Synchrotron Radiation in Nano-medicine and Advanced Health Care
    • Place of Presentation
      甲南大学ポートアイランドキャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] 量子ビームを用いた口腔扁平苔癬様疾患(OLL)中の微量金属元素の検出と状態分析2013

    • Author(s)
      杉山知子、和田敬広、宇尾基弘、本郷敏雄
    • Organizer
      第62回日本歯科理工学会学術講演会
    • Place of Presentation
      日本大学歯学部新潟生命歯学部
    • Related Report
      2013 Annual Research Report
  • [Presentation] SR-XRF, PIXE 及びXAFS を用いた口腔扁平苔癬様疾患中の微量元素の分布と状態分析2013

    • Author(s)
      杉山知子,和田敬広,宇尾基弘,尾曲大輔,小宮山一雄 沼子千弥,及川将一,草間幹夫
    • Organizer
      第16回XAFS討論会
    • Place of Presentation
      東京大学理学部
    • Related Report
      2013 Annual Research Report
  • [Presentation] 陽極酸化したチタンインプラント表面及び周囲骨中のチタンの状態分析2012

    • Author(s)
      宇尾基弘, 他5名
    • Organizer
      バイオインテグレーション学会第2回学術大会
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2012-01-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] XAFS用フィルム状試料の簡易作成法2012

    • Author(s)
      宇尾基弘・和田敬広
    • Organizer
      第15回XAFS討論会
    • Place of Presentation
      鳥取
    • Related Report
      2012 Annual Research Report
  • [Presentation] Rare earth oxide containing filler for dental composite resin2012

    • Author(s)
      Uo M., Nakajima Y., Asakawa Y., Wada T., Hongo T., Soga K., Kogo Y
    • Organizer
      24th Symposium and Annual Meeting of International Society for Ceramics in Medicine
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] XAFS analysis of TiO_2 nanotube formed on pure titanium and titanium alloy surfaces2011

    • Author(s)
      Uo M., 他7名
    • Organizer
      International Dental Materials Congress 2011
    • Place of Presentation
      延世大学(韓国・ソウル)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Sr enriched teeth ; structural analysis and mechanical properties2011

    • Author(s)
      Uo M., Asakura K., 他5名
    • Organizer
      International Dental Materials Congress 2011
    • Place of Presentation
      延世大学(韓国・ソウル)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 歯や歯科材料が受ける様々な力と歯科材料開発について2011

    • Author(s)
      宇尾基弘
    • Organizer
      日本セラミックス協会第24回秋季シンポジウム
    • Place of Presentation
      北海道大学(札幌)(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 放射光を用いた微小分析の臨床診断への応用2011

    • Author(s)
      宇尾基弘
    • Organizer
      第58回日本歯科理工学会学術講演会
    • Place of Presentation
      奥羽大学(郡山)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 放射光を用いたヒト組織標本中の微量元素の分布・状態分析と診断への応用

    • Author(s)
      宇尾基弘
    • Organizer
      X線分析研究懇談会第248回例会
    • Place of Presentation
      東京電機大学
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] 異種材料界面の測定と評価技術 第11章「歯と歯科材料における界面の測定と評価」2012

    • Author(s)
      宇尾基弘(分担執筆)
    • Total Pages
      562
    • Publisher
      テクノシステム
    • Related Report
      2012 Annual Research Report
  • [Book] 異種材料界面の測定と評価技術第11章「歯と歯科材料における界面の測定と評価」2012

    • Author(s)
      宇尾基弘(分担執筆)
    • Total Pages
      562
    • Publisher
      テクノシステム
    • Related Report
      2011 Annual Research Report

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Published: 2011-04-06   Modified: 2019-07-29  

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