Association of oral function with mental and physical senescence, and longevity: with a central focus on centenarians

• Project/Area Number: 23390440
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Osaka University
• Principal Investigator: IKEBE Kazunori 大阪大学, 歯学研究科(研究院), 准教授 (70273696)
• Co-Investigator(Kenkyū-buntansha): KAGAWA Ryosuke 大阪大学, 歯学部附属病院, 医員 (40448147) ; OKADA Tadashi 大阪大学, 歯学部附属病院, 医員 (60733186)
• Co-Investigator(Renkei-kenkyūsha): GONDO Yasuyuki 大阪大学, 人間科学研究科, 准教授 (40250196) ; KAMIDE Kei 大阪大学, 医学系研究科, 教授 (80393239)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000); Fiscal Year 2014: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2013: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2012: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2011: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
• Keywords: 高齢歯科学 / 健康長寿 / 口腔機能 / 咬合力 / 栄養 / 認知機能 / 運動機能 / 歯学 / 老化 / 歩行 / 高齢者 / 咬合咀嚼 / 長寿 / 咬合 / 口腔感覚 / 味覚 / QOL

Outline of Final Research Achievements

The aim of this study was to investigate the association of oral function and health and longevity, and to show the significance of maintaining and recovering masticatory function. It was a part of a multidisciplinary research project focused on the health and longevity of older Japanese conducted not only by dentists but also nutritionists psychologists, sociologists, and geriatrics physicians.
We examined 1000 septuagenarians (69-71 years), 973 octogenarians (79-81 years), and 272 nonagenarians (89-91 years). As the results, multivariate analyses after adjusting for major confounding factors showed that the occlusal force was significantly related to nutrient intakes, cognitive function and motor function.

Research Products

• [Journal Article] Association of personality traits with oral health-related quality of life independently of objective oral health status: A study of community-dwelling elderly Japanese. (2015)
  • Author(s): Takeshita H, Ikebe K, Kagawa R, Okada T, Gondo Y, Nakagawa T, Ishioka Y, Inomata C, Tada S, Matsuda K, Kurushima Y, Enoki K, Kamide K, Masui Y, Takahashi R, Arai Y, Maeda Y
  • Journal Title: J Dent Volume: 43 Pages: 342-349
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Association of periodontal status with occlusal force and food acceptability in 70-year-old adults: from SONIC Study. (2014)
  • Author(s): Okada T, Ikebe K, Inomata C, Takeshita H, Uota M, Mihara Y, Matsuda K, Kitamura M, Murakami S, Gondo Y, Kamide K, Masui Y, Takahashi R, Arai Y, Maeda Y
  • Journal Title: J Oral Rehabil Volume: 41 Pages: 912-919
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Significance of occlusal force for dietary fiber and vitamin intakes in independently living 70-year-old Japanese: from SONIC (Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians) Study (2014)
  • Author(s): C Inomata, K Ikebe, R Kagawa, H Okubo, S Sasaki, T Okada, H Takeshita, S Tada, K Matsuda, Y Kurushima, M Kitamura, S Murakami, Y Gondo, K Kamide, Y Masui, R Takahashi, Y Arai, Y Maeda
  • Journal Title: J Dent Volume: 42 Issue: 5 Pages: 556-564
  • DOI: 10.1016/j.jdent.2014.02.015
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] Factors related to the taste acuity among Japanese older people. (2014)
  • Author(s): Uota M, Ikebe K, Okada T, Inomata C, Takeshita H, Mihara Y, Tada S, Enoki K, Matsuda K, Kitamura M, Murakami S, Gondo Y, Kamide K, Masui Y, Ishizaki T, Arai Y, Maeda Y
  • Organizer: JADR
  • Place of Presentation: 大阪市
  • Year and Date: 2014-12-04
  • Invited
• [Presentation] 口腔機能と栄養．高齢者の自立喪失の様相と栄養の役割． (2014)
  • Author(s): 池邉一典
  • Organizer: 日本臨床栄養学会．
  • Place of Presentation: 東京都
  • Year and Date: 2014-10-04
  • Invited
• [Presentation] 高齢者の歯と口腔機能が健康長寿に及ぼす影響:文理融合型コホート研究より． (2014)
  • Author(s): 池邉一典
  • Organizer: 歯学教育改革コンソーシアム設立記念シンポジウム
  • Place of Presentation: 岡山市
  • Year and Date: 2014-09-27
  • Invited
• [Presentation] Association of salivary flow rate with dietary intakes in elderly. (2014)
  • Author(s): Mihara Y, Ikebe K, Inomata C, Matsuda K, Kagawa R, Okada T, Takeshita H, Uota M, Okubo H, Sasaki S, Gondo Y, Kamide K, Masui Y, Ishizaki T, Arai Y, Maeda Y
  • Organizer: IADR
  • Place of Presentation: Cape town
  • Year and Date: 2014-06-26
  • Invited
• [Presentation] 高齢者の口腔機能と全身の運動機能との関連：栄養摂取の介在について-SONIC研究より-．「これからの健康科学」～産業保健におけるダイバーシティ・マネジメントストラテジー～． (2014)
  • Author(s): 池邉一典
  • Organizer: 日本産業衛生学会
  • Place of Presentation: 岡山市
  • Year and Date: 2014-05-23
  • Invited
• [Presentation] Association of Personality and Oral Function with QOL (2013)
  • Author(s): Takeshita H, Ikebe K, Kagawa R, Okada T, Inomata C, Enoki K, Gondo Y, Kamide K, Masui Y, Takahashi R, Arai Y, Maeda Y
  • Organizer: 91th I.A.D.R. General Session
  • Place of Presentation: Seattle, USA
• [Presentation] Personality and satisfaction with chewing ability among community-dwelling 70-years Japanese (2012)
  • Author(s): Ikebe K, Takeshita H, Kagawa R, Okada T, Inomata C, Gondo Y, Kamide K, Nakagawa T, Masui Y, Takahashi R, Maeda Y
  • Organizer: 84th Annual Meeting, The American Prosthodontic Society
  • Place of Presentation: Chicago, USA
  • Year and Date: 2012-02-24
• [Presentation] 70歳における口腔機能と食品摂取状態に関する疫学的研究-SONIC研究より- (2012)
  • Author(s): 猪俣千里, 香川良介, 池邉一典, 岡田匡史, 武下肇, 前田芳信
  • Organizer: 平成23年度日本補綴歯科学会関西支部学術大会
  • Place of Presentation: 神戸市
  • Year and Date: 2012-02-04
• [Presentation] 80歳と70歳の口腔機能と全身の運動機能の比較 -SONIC研究より- (2012)
  • Author(s): 岡田匡史, 池邉一典, 香川良介, 武下肇, 猪俣千里,久留島悠子，本多真理子，宮下祐治，村井俊介，松田謙一，前田芳信
  • Organizer: 第23回日本老年歯科医学会 学術大会
  • Place of Presentation: つくば市
• [Presentation] 高齢者における口腔機能と運動機能との関係 (2011)
  • Author(s): 岡田匡史、香川良介、池邉一典、武下肇、猪俣千里、久留島悠子、宮下祐治、村井俊介、松田謙一、権藤恭之、前田芳信
  • Organizer: スポーツ歯科医学会
  • Place of Presentation: 千葉市
  • Year and Date: 2011-06-25
• [Presentation] 高齢者における口腔関連QOLと口腔感覚との関係 (2011)
  • Author(s): 武下肇, 池邉一典, 岡田匡史, 猪俣千里, 久留島悠子, 香川良介, 吉仲正記, 権藤恭之, 前田芳信
  • Organizer: 第22回日本老年歯科医学会学術大会
  • Place of Presentation: 東京都
  • Year and Date: 2011-06-17
• [Presentation] 全口腔法による70歳高齢者の味覚閾値についての検討 (2011)
  • Author(s): 吉仲正記, 池邉一典, 岡田匡文, 香川良介, 古谷暢子, 前田芳信
  • Organizer: 第22回日本老年歯科医学会学術大会
  • Place of Presentation: 東京都
  • Year and Date: 2011-06-17
• [Presentation] 高齢者における認知機能と口腔感覚との関係 (2011)
  • Author(s): 岡田匡史, 池邉一典, 武下肇, 猪俣千里, 久留島悠子, 香川良介, 吉仲正記, 権藤恭之, 前田芳信
  • Organizer: 第22回日本老年歯科医学会学術大会
  • Place of Presentation: 東京都
  • Year and Date: 2011-06-16
• [Presentation] 70歳の口腔機能と栄養摂取状態に関する実態調査 (2011)
  • Author(s): 猪俣千里, 香川良介, 池邉一典, 岡田匡史, 大久保公美, 権藤恭之, 前田芳信
  • Organizer: 第120回日本補綴歯科学会学術大会
  • Place of Presentation: 広島市
  • Year and Date: 2011-05-21
• [Presentation] 咬合力と歩行の速さとの関連 タンパク質摂取の媒介の検証 -SONIC studyより-
  • Author(s): 岡田匡史，池邉一典，香川良介，武下肇，猪俣千里，多田紗弥夏，魚田真弘，三原佑介，前田芳信
  • Organizer: 日本補綴歯科学会
  • Place of Presentation: 仙台市
• [Presentation] Association between bite force and skeletal muscle function in 70 and 80 years old adults
  • Author(s): Okada T, Ikebe K, Kagawa R, Takeshita H, Inomata C, Tada S, Uota M, Mihara Y, Maeda Y
  • Organizer: Joint Congress of CPS-JPS-KAP
  • Place of Presentation: Jeju, Korea
• [Presentation] 70と80歳の高齢者における咬合力と全身の運動機能との関連 -SONIC study より-
  • Author(s): 岡田匡史，池邉一典，香川良介，武下 肇，猪俣千里，多田紗弥夏，魚田真弘，三原佑介，前田芳信
  • Organizer: 日本補綴歯科学会
  • Place of Presentation: 福岡市
• [Presentation] 栄養摂取を介した咬合力と運動機能との相互関係について
  • Author(s): 岡田匡史, 池邉一典, 香川良介, 武下肇, 猪俣千里, 多田紗弥夏，魚田真弘，三原佑介，権藤恭之，神出計，高橋龍太郎，増井幸恵，新井康通，前田芳信
  • Organizer: 日本老年歯科医学会
  • Place of Presentation: 大阪市
• [Presentation] 高齢者における口腔機能と認知機能低下の関係-SONIC studyより-
  • Author(s): 武下 肇， 池邉一典， 香川良介， 岡田匡史， 猪俣千里， 多田紗弥夏，魚田真弘，三原佑介，権藤恭之，神出計，高橋龍太郎，増井幸恵，新井康通，前田芳信
  • Organizer: 日本老年歯科医学会
  • Place of Presentation: 大阪市