Impact of oral functional and inflamatory factors on the incidence of metabolic syndrome

• Project/Area Number: 23390441
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Prosthetic dentistry
• Research Institution: Osaka University
• Principal Investigator: ONO Takahiro 大阪大学, 歯学研究科(研究院), 准教授 (30204241)
• Co-Investigator(Kenkyū-buntansha): KOKUBO Yoshihiro 独立行政法人国立循環器病研究センター, 予防健診部, 医長 (20393217) ; TANAKA Muneo 大阪大学, 歯学部附属病院, 講師 (90263300) ; SHIROSHITA Naoko NAOKO), 歯学部附属病院, 医員 (10448110) ; KATO Satoshi 大阪大学, 歯学部附属病院, 医員 (10610876) ; KONDOH Jyugo 大阪大学, 歯学部附属病院, 医員 (80610873) ; KONDOH Sato 大阪大学, 歯学部附属病院, 医員 (40610861) ; FUJIWARA Shigehiro 大阪大学, 歯学部附属病院, 医員 (70711034)
• Co-Investigator(Renkei-kenkyūsha): NOKUBI Takashi 大阪大学, 名誉教授 (80028753) ; FURUKAWA Yoko 京都光華女子大学, 健康科学部, 講師 (30582267)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000); Fiscal Year 2013: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2012: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000); Fiscal Year 2011: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
• Keywords: 口腔健康 / メタボリックシンドローム / 生活習慣病 / 肥満 / 食習慣 / 歯周病 / 咀嚼 / 高血圧 / 咀嚼能力

Research Abstract

This study assessed the relationship between oral health and general health in a Japanese urban population. Below results were found; 1. Decrease of occlusal support related to obesity relating feeding behaviors. 2. Periodontal disease affected masticatory performance not only occlusion was established by natural dentition but also if occlusal support decreased. 3. Decline of masticatory performance related to atherosclerosis. 4. There was an additive relationship between oral health disorders and risk of hypertension.

Research Products

• [Journal Article] The effect of periodontal status and occlusal support on masticatory performance : the Suita study (2014)
  • Author(s): Kosaka T, Ono T, Yoshimuta Y, Kida M, Kikui M, Nokubi T, Maeda Y, Kokubo Y, Watanabe M, Miyamoto Y
  • Journal Title: Journal of Clinical Periodontology Volume: vol.41 Pages: 497-503
  • Peer Reviewed
• [Journal Article] Additive interaction of oral health disorders on risk of hypertension in a Japanese urban population : The Suita Study (2014)
  • Author(s): Iwashima Y, Kokubo Y, Ono T, Yoshimuta Y, Kida M, Kosaka T, Maeda Y, Kawano Y, Miyamoto Y
  • Journal Title: American Journal of Hypertension Volume: vol. 27 Pages: 710-719
  • Peer Reviewed
• [Journal Article] The effect of periodontal status and occlusal support on masticatory performance: the Suita study. (2014)
  • Author(s): Kosaka, T., Ono, T., Yoshimuta, Y., Kida, M., Kikui, M., Nokubi, T., Maeda, Y., Kokubo, Y., Watanabe, M., Miyamoto, Y.
  • Journal Title: Journal of Clinical Periodontology Volume: 41 Issue: 5 Pages: 497-503
  • DOI: 10.1111/jcpe.12241
  • Peer Reviewed
• [Journal Article] Additive interaction of oral health disorders on risk of hypertension in a Japanese urban population: The Suita Study. (2014)
  • Author(s): Iwashima, Y., Kokubo, Y., Ono, T., Yoshimuta, Y., Kida, M., Kosaka, T., Maeda, Y., Kawano, Y., Miyamoto, Y.
  • Journal Title: American Journal of Hypertension Volume: 27 Issue: 5 Pages: 710-719
  • DOI: 10.1093/ajh/hpt227
  • Peer Reviewed
• [Journal Article] 咀嚼能力関連因子と食行動との関係 : 吹田研究 (2013)
  • Author(s): 竹村佳代子, 吉牟田陽子, 小野高裕, 小久保喜弘, 來田百代, 高阪貴之, 安井 栄, 野首孝祠, 前田芳信
  • Journal Title: 日本咀嚼学会雑誌 Volume: 23巻 Pages: 81-89
  • Peer Reviewed
• [Journal Article] 咀嚼能力関連因子と食行動との関係：吹田研究． (2013)
  • Author(s): 竹村佳代子，吉牟田陽子, 小野高裕，小久保喜弘，來田百代，高阪貴之，安井 栄，野首孝祠, 前田芳信
  • Journal Title: 日本咀嚼学会雑誌 Volume: 23 Pages: 81-89
  • Peer Reviewed
• [Presentation] Association between oral health disorders and risk of hypertension in a Japanese urban population : The Suita Study (2014)
  • Author(s): Iwashima Y, Kokubo Y, Ono T, Kawano Y, Miyamoto Y
  • Organizer: 日本循環器学会第78回学術大会
  • Place of Presentation: 東京
  • Year and Date: 2014-03-21
• [Presentation] 歯周組織の健康状態と咬合支持が咀嚼能力に及ぼす影響 : 吹田研究 (2013)
  • Author(s): 高阪貴之, 小野高裕, 吉牟田陽子, 竹村佳代子, 來田百代, 前田芳信, 小久保喜弘, 野首孝祠
  • Organizer: 日本老年歯科医学会第24回学術大会
  • Place of Presentation: 大阪
  • Year and Date: 2013-06-05
• [Presentation] 都市部一般住民における口腔健康と生活習慣病との関係を探る-吹田研究の挑戦- (2013)
  • Author(s): 小野高裕
  • Organizer: 日本老年歯科医学会第24回学術大会シンポジウム
  • Place of Presentation: 大阪
  • Year and Date: 2013-06-05
• [Presentation] 都市部一般住民における動脈硬化のリスクと咀嚼能力関連因子との関係 : 吹田研究 (2013)
  • Author(s): 來田百代, 小野高裕, 吉牟田陽子, 小久保喜弘, 竹村佳代子, 高阪貴之, 阪上 穣, 前田芳信, 野首孝祠
  • Organizer: 日本補綴歯科学会第122回学術大会
  • Place of Presentation: 福岡
  • Year and Date: 2013-05-18
• [Presentation] 都市部一般住民における食後高血糖と咬合支持域との関係-吹田研究- (2011)
  • Author(s): 吉牟田陽子、小野高裕、加登聡、竹村佳代子、來田百代、小久保喜弘、池邉一典、前田芳信、野首孝祠
  • Organizer: 第22回日本老年歯科医学会
  • Place of Presentation: 東京都
  • Year and Date: 2011-06-16
• [Presentation] Tooth loss is associated with Metabolic Syndrome in Japanese woman over 80 years old-The Suita Study (2011)
  • Author(s): Takahiro Ono, Satoshi Kato, Yoko Yoshimuta, Yoko Hasegawa, Yoshinobu Maeda
  • Organizer: European College of Gerodontology
  • Place of Presentation: ゲント市(ベルギー)
  • Year and Date: 2011-05-19
• [Presentation] 都市部一般住民における食行動と口腔健康との関係－吹田研究－
  • Author(s): 竹村佳代子
  • Organizer: 第23回日本咀嚼学会学術大会
  • Place of Presentation: 札幌市
• [Presentation] 都市部一般住民における動脈硬化のリスクと咀嚼能力関連因子との関係－吹田研究－
  • Author(s): 來田百代
  • Organizer: 第23回日本咀嚼学会学術大会
  • Place of Presentation: 札幌市
• [Presentation] 歯周組織の健康状態が咀嚼能率に及ぼす影響－吹田研究
  • Author(s): 高阪貴之
  • Organizer: 第23回日本咀嚼学会学術大会
  • Place of Presentation: 札幌市
• [Presentation] Relationship between carotid intima-media thickness and periodontal disease in an urban Japanese population: The Suita Study
  • Author(s): Momoyo KIDA
  • Organizer: International Stroke Conference 2013
  • Place of Presentation: Hawaii, USA