Development of a fluorinated tissue conditioner with high durability and healing acceleration function by bioactive substances
| Project/Area Number |
23390446
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
MURATA Hiroshi 長崎大学, 医歯(薬)学総合研究科, 教授 (40229993)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIMURA Masahiro 鹿児島大学, 医歯学総合研究科(歯学系), 教授 (00294570)
KOJIO Ken 長崎大学, 工学研究科, 准教授 (20346935)
HONG Guang 東北大学, 歯学研究科, 助教 (70363083)
TORISU Tetsurou 長崎大学, 病院, 講師 (80264258)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2011: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
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| Keywords | 歯学 / 高分子・物性 / 補綴用材料 / 粘膜調整材 / レオロジー / 動的粘弾性 / フッ素系モノマー / 高分子構造・物性 / 光触媒 / 粘膜調整剤 |
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| Research Abstract |
The purpose of this research is to develop a fluorinated tissue conditioner with high durability and healing acceleration function by bioactive substances. The gelation characteristics, dynamic viscoelastic properties, their changes with time, solubility of components, and cytotoxicity were evaluated. The liquid component that showed high cytotoxicity was determined. The problems of current tissue conditioners were discussed. The system of three dimensional culture by gingival epithelia cell and gingival fibroblast was also developed. Subsequently, the efficacy of fluorinated monomers and healing acceleration were examined. The fluorinated monomers produced the materials having higher durability.
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Report
(4 results)
Research Products
(96 results)
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[Journal Article] 義歯管理に関する臨床的エビデンス2013
Author(s)
馬場一美, 塚崎弘明, 笛木賢治, 村田比呂司, 尾澤昌悟, 松香芳三, 小野高裕, 會田英紀, 近藤尚知, 玉置勝司, 藤澤政紀, 矢谷博文, 古谷野潔
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Journal Title
日本歯科医師会雑誌
Volume: 66
Pages: 764-774
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[Book] 第2章9. 受診困難か, あるいは応急的処置として・・・義歯安定剤.濱田泰三, 水口俊介, 秋葉徳寿, 貞森紳丞, 鈴木哲也, 細井紀雄, 村田比呂司, 米山喜一, 織田展輔, 洪 光, 市川哲雄, 岡崎定司, 河相安彦, 木本克彦. 義歯のケア-歯科衛生士のための副読本-. 日本義歯ケア学会監修2011
Author(s)
村田比呂司
Total Pages
44
Publisher
デンタルダイヤモンド社, 東京
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