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Investigation on molecular epidemiology, life cycle and transmission to humans of broad tapeworms in Chile

Research Project

Project/Area Number 23406010
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Parasitology (including Sanitary zoology)
Research InstitutionNational Institute of Infectious Diseases

Principal Investigator

YAMASAKI Hiroshi  国立感染症研究所, その他部局等, 室長 (00138207)

Co-Investigator(Kenkyū-buntansha) 倉持 利明  国立科学博物館 (80277590)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2013: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Keywords裂頭条虫 / チリ / 分子疫学 / 生活史 / 感染経路 / サケ科魚類 / 裂頭条虫症
Research Abstract

Chile is a country where produces farmed salmon/trout and Japan is one of countries where the salmons are consumed. Since it is known that larvae of broad tapeworms are parasitized in the salmon/trout in Chile and the occurrence of diphyllobothriosis caused by the infection of the larvae is concerned. We investigated the prevalence and intensity of the parasites harboring in salmon/trout in two lakes, Llanquihue and Panguipulli, in southern Chile during 2012 to 2014. We collected 631 larvae from salmon/trout and the larvae were reinforced as being Diphyllobothrium latum and D. dendriticum by DNA analysis. Most larvae were detected in the viscera of salmon/trout, but some were found in the edible muscle. Although little information currently exists on the relationship between D. latum and salmon/trout in the northern hemisphere, it is considered likely that salmon/trout play an important role in the transmission of D. latum to humans in South America.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (48 results)

All 2014 2013 2012 2011 Other

All Journal Article (26 results) (of which Peer Reviewed: 16 results) Presentation (22 results) (of which Invited: 2 results)

  • [Journal Article] Molecular detection of Diphyllobothriumnihonkaiense in humanshumans, China. Emerg2014

    • Author(s)
      Chen S, Ai L, Zhang Y, Chen J, ZhangW, Li Y, Muto M, Morishima Y, Sugiyama H, Xu X, Zhou X, Yamasaki H
    • Journal Title

      Infect. Dis

      Volume: 20 Pages: 315-318

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 日本海裂頭条虫症の4 小児例2014

    • Author(s)
      河口亜津彩, 星野恵美子, 黒岩由紀, 母坪智行, 布施茂登, 森俊彦, 山崎浩
    • Journal Title

      小児科臨床

      Volume: 67 Pages: 451-454

    • Related Report
      2013 Final Research Report
  • [Journal Article] Digenean trematodes of deep-sea fishes from the Sea of Japan2014

    • Author(s)
      Kuramochi T
    • Journal Title

      National Museum of Nature and Science Monographs

      Volume: 44 Pages: 29-37

    • Related Report
      2013 Final Research Report
  • [Journal Article] Molecular detection of Diphyllobothrium nihonkaiense in humans, China.2014

    • Author(s)
      Chen S, Ai L, Zhang Y, Chen J, Zhang W, Li Y, Muto M, Morishima Y, Sugiyama H, Xu X, Zhou X, Yamasaki H.
    • Journal Title

      Emerging Infectious Diseases

      Volume: 20 Issue: 2 Pages: 315-318

    • DOI

      10.3201/eid2002.121889

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 日本海裂頭条虫症の4小児例2014

    • Author(s)
      河口亜津彩, 星野恵美子, 黒岩由紀, 母坪 智行, 布施茂登, 森 俊彦, 山﨑 浩
    • Journal Title

      小児科臨床

      Volume: 67 Pages: 451-454

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 食品による寄生動物感染症8 蠕虫感染症(3) 条虫2013

    • Author(s)
      山崎浩
    • Journal Title

      J. Antibact. Antifung. Agents

      Volume: 41 Pages: 227-236

    • Related Report
      2013 Final Research Report
  • [Journal Article] 生シラスの生食による感染が疑われたクジラ複殖門条虫症1例2013

    • Author(s)
      川合覚, 石原優吾, 笹井貴子, 高橋史成, 桐木雅史, 林 尚子, 山崎浩, 平石秀幸, 千種雄一
    • Journal Title

      獨協医誌

      Volume: 40 Pages: 189-192

    • Related Report
      2013 Final Research Report
  • [Journal Article] 食品による寄生動物感染症8 蠕虫感染症 (3) 条虫2013

    • Author(s)
      山﨑 浩
    • Journal Title

      防菌防黴

      Volume: 412013

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 生シラスの生食による感染が疑われたクジラ 複殖門条虫症1例2013

    • Author(s)
      川合 覚, 石原優吾, 笹井貴子,高橋史成, 桐木雅史, 林 尚子, 山﨑 浩, 平石秀幸, 千種 雄一
    • Journal Title

      獨協医誌

      Volume: 40

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Current satus and perspectives of cysticercosis and taeniasis in Japan2013

    • Author(s)
      Yamasaki H
    • Journal Title

      Korean J.Parasitology

      Volume: 51卷 Issue: 1 Pages: 19-29

    • DOI

      10.3347/kjp.2013.51.1.19

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Complete mitochondrial genomes of Diplogonoporus balaenopterae and Diplogonoporus grandis (Cestoda : Diphyllobothriidae) and clarification of their taxonomic relationships2012

    • Author(s)
      Yamasaki H., et al
    • Journal Title

      Parasitology International

      Volume: 61 Issue: 2 Pages: 260-266

    • DOI

      10.1016/j.parint.2011.10.007

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Validity of the bear tapeworm Diphyllobothrium ursi (Cestoda:Diphyllobothriidae) based on morphological and molecular markers2012

    • Author(s)
      Yamasaki H., Muto M., YamadaM., Aizono N., Rausch R.L.
    • Journal Title

      Journal of Parasitology

      Volume: 98 Issue: 6 Pages: 1243-1247

    • DOI

      10.1645/ge-3063.1

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sparganosis mansoni on abdominal skin, mimicking folliculitis and diagnosed by analysis of the mitochondrial cytochrome c oxidase subunit 1 gene, using polymerase chain reaction2012

    • Author(s)
      Nonomura Y., Otsuka A., Endo Y., Fujisawa A., Nakajima N., Minamiguchi S., Miyagawa-Hayashino A., Yamada M., Tegoshi T., Yamasaki H., Kabashima K., Miyachi Y., Tanioka M.
    • Journal Title

      European Journal of Dermatology

      Volume: 22 Issue: 6 Pages: 806-807

    • DOI

      10.1684/ejd.2012.1876

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two pediatric cases of Diphyllobothrium nihon-kaiense infection in summer (July-August) 20102012

    • Author(s)
      Ikeda T., Tamura D., Sato Y., Ichihashi K., Matsuo-ka H., Yamasaki H.
    • Journal Title

      Pediatrics International

      Volume: 54 Issue: 1 Pages: 163-165

    • DOI

      10.1111/j.1442-200x.2011.03529.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Validity of the bear tapeworm Diphyllobothrium ursi (Cestoda : Diphyllobothriidae) based on morphological and molecular markers. Journal of Parasitology2012

    • Author(s)
      Yamasaki H., et al
    • Journal Title

      Journal of Parasitology

      Volume: (accepted)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two pediatric cases of Diphyllobothrium nihonkaiense Infection in Summer 20102012

    • Author(s)
      Ikeda T., et al
    • Journal Title

      Pediatrics International

      Volume: 54(in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 生食のリスク.食肉・野生動物の生食と寄生虫症2012

    • Author(s)
      山峙浩, 他
    • Journal Title

      公衆衛生

      Volume: 76 Pages: 30-36

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Molecular identification of a causative parasite species using formalin-fixed paraffin embedded (FFPE) tissues of a complicated human pulmonary sparganosis case without decisive clinical diagnosis2011

    • Author(s)
      Koonmee S., et al
    • Journal Title

      Parasitology International

      Volume: 60 Issue: 4 Pages: 460-464

    • DOI

      10.1016/j.parint.2011.07.018

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] パモ酸ピランテル単回投与による駆虫に抵抗性を示したアメリカ鉤虫症の1例2011

    • Author(s)
      水野泰孝, 他
    • Journal Title

      Clinical Parasitology

      Volume: 22 Pages: 65-67

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 当院で経験した4例のアジア条虫症について2011

    • Author(s)
      中村(内山)ふくみ, 他
    • Journal Title

      Clinical Parasitology

      Volume: 22 Pages: 72-74

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 2010年に関東地方で発生が相次いだアジア条虫症について2011

    • Author(s)
      山崎浩, 他
    • Journal Title

      Clinical Parasitology

      Volume: 22 Pages: 75-78

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 2010年6月以降に続けて関東地方で発生が確認された新興寄生虫感染症としてのアジア条虫症2011

    • Author(s)
      山崎浩, 他
    • Journal Title

      病原微生物検出情報

      Volume: 32 Pages: 106-107

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 豚あるいは牛レバー刺し摂食によるアジア条虫症の4例2011

    • Author(s)
      中村(内山)ふくみ, 他
    • Journal Title

      病原微生物検出情報

      Volume: 32 Pages: 107-108

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 有棘顎口虫による幼虫移行症の1例2011

    • Author(s)
      青笹直彦, 他
    • Journal Title

      皮膚科の臨床

      Volume: 53 Pages: 887-890

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] マス生食によると思われた日本海裂頭条虫症の1例2011

    • Author(s)
      太田和義, 他
    • Journal Title

      日本内科学会雑誌

      Volume: 100 Pages: 3336-3338

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 相模湾湯河原沖で捕獲された雌のメガマウスザメ-内部形態および寄生虫-2011

    • Author(s)
      金子和久, 他
    • Journal Title

      動物園水族館雑誌

      Volume: 52 Pages: 41-58

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Phylogenetic analysis of Diphyllobothrium dendriticum from Chile based on mitochondrial DNA2014

    • Author(s)
      Yamasaki H, Ichimura S, Kuramochi T, Mercado R
    • Organizer
      第13回国際寄生虫学会
    • Place of Presentation
      メキシコシティ, メキシコ
    • Related Report
      2013 Final Research Report
  • [Presentation] Diphyllobothrium/diphyllobothriosis in Chile2014

    • Author(s)
      Yamasaki H, Ichimura S, Kuramochi T, Mercado R
    • Organizer
      第83回日本寄生虫学会大会
    • Place of Presentation
      愛媛県松山市
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Phylogenetic analysis of Diphyllobothrium dendriticum from Chile based on mitochondrial DNA2014

    • Author(s)
      Yamasaki H, Ichimura S, Kuramochi T, Mercado R.
    • Organizer
      第13回国際寄生虫学会議
    • Place of Presentation
      Mexico City, Mexico
    • Related Report
      2013 Annual Research Report
  • [Presentation] Diphyllobothrium plerocercoids parasitizing in feral salmonids in Chile2013

    • Author(s)
      Mercado R, Ichimura S, Yamasaki H, Kuramochi T
    • Organizer
      第73回日本寄生虫学会東日本大会
    • Place of Presentation
      東京・上野
    • Year and Date
      2013-10-12
    • Related Report
      2013 Final Research Report
  • [Presentation] 日本海産深海性魚類から得られた住血吸虫について2013

    • Author(s)
      倉持利明
    • Organizer
      第73回日本寄生虫学会東日本大会
    • Place of Presentation
      東京・上野
    • Year and Date
      2013-10-12
    • Related Report
      2013 Final Research Report
  • [Presentation] 四葉目条虫類の幼生のDNA 解析による同定の試み2013

    • Author(s)
      倉島陽, 小川和夫, 倉持利明, 藤田敏彦
    • Organizer
      第73回日本寄生虫学会東日本大会
    • Place of Presentation
      東京・上野
    • Year and Date
      2013-10-12
    • Related Report
      2013 Final Research Report
  • [Presentation] Current status of food-borne parasitic diseases in Japan2013

    • Author(s)
      Yamasaki H.
    • Organizer
      第28回国際化学療法・感染症会議(シンポジウム)
    • Place of Presentation
      横浜市
    • Related Report
      2013 Final Research Report
  • [Presentation] Current status of food-borne parasitic diseases in Japan2013

    • Author(s)
      Yamasaki H.
    • Organizer
      第28回国際化学療法・感染症会議(シンポジウム)
    • Place of Presentation
      横浜市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 中国で発生した裂頭条虫症の原因種に関する分子同定2012

    • Author(s)
      山崎浩, 他
    • Organizer
      第81回日本寄生虫学会大会
    • Place of Presentation
      西宮
    • Year and Date
      2012-03-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 千葉県南房総市沖の定置網に羅網したコククジラから得られた寄生蠕虫3種について2012

    • Author(s)
      倉持利明, 他
    • Organizer
      第81回日本寄生虫学会大会
    • Place of Presentation
      兵庫
    • Year and Date
      2012-03-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 関東地方で発生が相次いだアジア条虫症2012

    • Author(s)
      山崎浩, 他
    • Organizer
      第81回日本寄生虫学会大会
    • Place of Presentation
      西宮
    • Year and Date
      2012-03-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] Current status of food-borne cestodiasis in Japan2012

    • Author(s)
      Yamasaki H.
    • Organizer
      International Workshop on “Emerging parasitic zoonoses: epidemiology, diagnosis and prevention”
    • Place of Presentation
      Hanoi, VIetnam
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Genetic polymorphisms of Diphyllobothrium species found in fishes fromLake Llanquihue, sourthern Chile2012

    • Author(s)
      Yamasaki H.
    • Organizer
      XVIII International Congress of Tropical Medicineand Malaria
    • Place of Presentation
      Rio de Janeiro, Brazil
    • Related Report
      2012 Annual Research Report
  • [Presentation] 東北地方太平洋側の深海域に生息する魚類の二生吸虫相2011

    • Author(s)
      倉持利明
    • Organizer
      第71回日本寄生虫学会東日本支部大会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Intragastric distribution of Nematoda, Anisakidae, parasitizing sperm whale, Physeter macrocephalus in the Western North Pacific Ocean2011

    • Author(s)
      Tanaka, M., et al
    • Organizer
      19th Biennial Conference on the Biology of Marine Mammals
    • Place of Presentation
      フロリダ
    • Year and Date
      2011-09-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 2010年に関東地方で発生が相次いだアジア条虫症について2011

    • Author(s)
      山崎浩, 他
    • Organizer
      第22回日本臨床寄生虫学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] パモ酸ピランテル単回投与による駆虫に抵抗性を示したアメリカ鉤虫症の1例2011

    • Author(s)
      水野泰孝, 他
    • Organizer
      第22回日本臨床寄生虫学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] 当院で経験しだ4例のアジア条虫症について2011

    • Author(s)
      中村(内山)ふくみ, 他
    • Organizer
      第22回日本臨床寄生虫学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] 相模灘および伊豆-小笠原諸島産魚類の二生吸虫相2011

    • Author(s)
      倉持利明
    • Organizer
      第80回日本寄生虫学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] Present status of Taenia asiatica infection as an emerging disease in Japan2011

    • Author(s)
      Yamasaki H, et al
    • Organizer
      1^<st> Symposium on current perspectives of Taenia asiatica researches
    • Place of Presentation
      Osong, Chungbuk, Korea
    • Related Report
      2011 Annual Research Report
  • [Presentation] Diphyllobothrium plerocercoids parasitizing in feral salmonids in Chile

    • Author(s)
      Mercado R, Ichimura S, Yamasaki H, Kuramochi T.
    • Organizer
      第73回日本寄生虫学会東日本大会
    • Place of Presentation
      東京・上野
    • Related Report
      2013 Annual Research Report
  • [Presentation] 鯨類寄生蠕虫における宿主−寄生体関係

    • Author(s)
      倉持利明
    • Organizer
      日本哺乳類学会2012年度大会
    • Place of Presentation
      神奈川県相模原市
    • Related Report
      2012 Annual Research Report

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Published: 2011-04-06   Modified: 2019-07-29  

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