| Project/Area Number |
23406011
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 海外学術 |
|---|
| Research Field |
Bacteriology (including Mycology)
|
|---|
| Research Institution | Niigata University (2013)
Osaka City University (2011-2012) |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
HAMANO Shinjiro 長崎大学, 熱帯医学研究所, 教授 (70294915)
KOBAYASHI Kazuo 国立感染症研究所, 免疫部, 部長 (20142432)
ATO Manabu 国立感染症研究所, 免疫部, 部長 (20392318)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
SHIMADA Masaaki 長崎大学, 熱帯医学研究所, 教授 (70124831)
KANEKO Satoshi 長崎大学, 熱帯医学研究所, 教授 (00342907)
|
|---|
| Project Period (FY) |
2011-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2013: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
|
|---|
| Keywords | 感染症 / 結核 / 寄生虫 / 栄養 / アフリカ / 潜在性結核 / 診断 / 活動性結核 / 免疫応答 |
|---|
| Research Abstract |
Tuberculosis is deadly infectious diseases found worldwide and remains a leading public health problem. The majority of TB cases arise from latent Mycobacterium tuberculosis infection (LTBI). However the risk of LTBI and development of TB from infection is largely unknown. We conducted comprehensive health survey in TB endemic area, Kenya Africa. In this study, 627 children from schools situated in two different sites, Mbita and Kwale districts, Kenya were enrolled. And we conducted comprehensive survey including biochemical analysis of blood and detection of infections of parasitic and bacterial pathogens. We found latent antigens M. tuberculosis is a candidates for more sensitive diagnosis of LTBI and hookworm infection is a risk of Mycobacterium tuberculosis infection besides active tuberculosis.
|
