| Project/Area Number |
23406024
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Hygiene and public health
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAKEDA Satoru 順天堂大学, 医学部, 教授 (20143456)
SHIMIZU Toshiaki 順天堂大学, 医学部, 教授 (30260889)
CHIBA Momoko 順天堂大学, 医学部, 客員教授 (80095819)
SHINOHARA Atsuko 清泉女子大学, 人文科学研究所, 教授 (90157850)
VIEGH Mohsen 労働安全衛生総合研究所, 研究員 (80455485)
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| Co-Investigator(Renkei-kenkyūsha) |
NISHIOKA Emiko 防衛医科大学, 看護学部, 教授 (70550797)
KITAMURA Fumihiko 順天堂大学, 医学部, 准教授 (20301145)
HOSOKAWA Mayuko 順天堂大学, 医学部, 助教 (70582013)
MATSUKAWA Takehisa 順天堂大学, 医学部, 助教 (60453586)
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| Project Period (FY) |
2011-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2014: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
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| Keywords | 小児 / 微量元素 / 環境 / 健康影響 / 衛生 / 開発途上国 / 有害微量元素 / 非顕性影響 |
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| Outline of Final Research Achievements |
We have conducted epidemiological surveys on the reproductive and developmental effects of lead and other trace metals in Tehran, Dalian, Serpong and Tokyo. The survey in Tehran, we revealed that a relatively low level of prenatal lead exposure (mean < 6.5 micro-g/dL) associated with lower developmental scores in early childhood. The survey in Dalian revealed that newborn birth weight were affected by manganese concentration in mother whole blood and/or umbilical cord blood. The survey in Serpong revealed that lower socioeconomic status were associated with increased blood lead concentrations, especially in female children. The survey in Tokyo suggested that very low-level exposure to lead ( < 5.0 micro-g/dL) in early gestation could be a risk factor for reduced birth weight in male offspring. Lead, manganese and other metals may cause adverse reproductive and developmental effects at levels believed to be safe.
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