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Improved diagnosis for pediatric tuberculosis in Bangladesh

Research Project

Project/Area Number 23406034
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Pediatrics
Research InstitutionUniversity of Tsukuba

Principal Investigator

WAGATSUMA Yukiko  筑波大学, 医学医療系, 教授 (40400676)

Co-Investigator(Kenkyū-buntansha) MA Enbo  筑波大学, 医学医療系, 助教 (00590770)
FUKUSHIMA Takashi  筑波大学, 医学医療系, 准教授 (30323299)
SUMAZAKI Ryo  筑波大学, 医学医療系, 教授 (40163050)
OKADA Masafumi  筑波大学, 医学医療系, 講師 (70375492)
Research Collaborator 御手洗 聡  結核予防会, 結核研究所
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2013: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2012: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2011: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Keywords国際研究者交流 / 国際情報交換 / バングラデシュ / 小児科学 / 感染症 / 結核 / 臨床研究 / 公衆衛生 / 医療・福祉 / 細菌 / 臨床 / 社会医学
Research Abstract

The objectives of the study were to evaluate the feasibility of using urine-based techniques for the diagnosis of tuberculosis among children and to compare the effectiveness of new diagnostic tools against the existing clinical tools for diagnosis of tuberculosis in children. Among 97 suspected cases that were examined for all tests, 24 cases were positive for any tests. Although only 11cases were smear positive, additional 7cases by MGIT, 5 cases by PCR using respiratory samples, and 1 case by TB-LAMP using urine samples were further identified. This study showed diagnosis capacity could increase to double by applying respiratory and urine samples for liquid culture and PCR.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (10 results)

All 2013 2011 Other

All Presentation (7 results) Remarks (3 results)

  • [Presentation] バングラデシュにおける小児結核研究. 日本公衆衛生雑誌2013; 60 : 6122013

    • Author(s)
      我妻ゆき子, 馬恩博, 御手洗聡
    • Organizer
      第72回日本公衆衛生学会総会
    • Place of Presentation
      三重
    • Year and Date
      2013-10-23
    • Related Report
      2013 Final Research Report
  • [Presentation] Tuberculosis. Int J Tuber Lung Dis 2013; 17 : S1252013

    • Author(s)
      Banu S, Kabir S, Rahman MS, Sharna MS, Dey H, Khatun R, Wagatsuma Y, Mitarai S
    • Organizer
      44th World Conference on Lung Health of the International Union against Tuberculosis and Lung Disease
    • Place of Presentation
      Paris, France
    • Related Report
      2013 Final Research Report
  • [Presentation] Comparison of Centrifugation and Bead-based Method to Isolate Mycobacterium tuberculosis. Int J Tuber Lung Dis 2013; 17 : S2222013

    • Author(s)
      Yoshimatsu S, Kato T, Aono A, Chikamatsu K, Yamada H, Mitarai S
    • Organizer
      44th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease
    • Place of Presentation
      Paris, France
    • Related Report
      2013 Final Research Report
  • [Presentation] バングラデシュにおける小児結核研究2013

    • Author(s)
      我妻ゆき子,馬 恩博,御手洗聡.
    • Organizer
      第72回日本公衆衛生学会総会
    • Place of Presentation
      三重, 日本
    • Related Report
      2013 Annual Research Report
  • [Presentation] Feasibility of using Non-Respiratory Specimens for Diagnosis of Child Tuberculosis.2013

    • Author(s)
      Banu S, Kabir S, Rahman MS, Sharna MS, Dey H, Khatun R, Wagatsuma Y, Mitarai S.
    • Organizer
      44th World Conference on Lung Health of the International Union against Tuberculosis and Lung Disease
    • Place of Presentation
      Paris, France
    • Related Report
      2013 Annual Research Report
  • [Presentation] Comparison of Centrifugation and Bead-based Method to Isolate Mycobacterium tuberculosis.2013

    • Author(s)
      Yoshimatsu S, Kato T, Aono A, Chikamatsu K, Yamada H, Mitarai S.
    • Organizer
      44th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease
    • Place of Presentation
      Paris, France
    • Related Report
      2013 Annual Research Report
  • [Presentation] Beads-based specimen concentration for mycobacterial culture2011

    • Author(s)
      S.Mitarai
    • Organizer
      21st ECCMID
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2011-05-07
    • Related Report
      2011 Annual Research Report
  • [Remarks] http://www.md.tsukuba.ac.jp/epidemiology/

    • Related Report
      2013 Annual Research Report
  • [Remarks] http://www.icddrb.org

    • Related Report
      2013 Annual Research Report
  • [Remarks] 臨床試験・臨床疫学研究室

    • URL

      http://www.md.tsukuba.ac.jp/epidemiology/

    • Related Report
      2012 Annual Research Report

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Published: 2011-04-06   Modified: 2019-07-29  

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