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DIAGNOSIS, MOLECULAR EPIDEMIOLOGY AND PRIVENTION OF PEDIATRIC VIRUS INFECTIOUOS DISEASES INCLUDING EMERGING INFECTIOUS DISEASES IN ASIA BY USHING NEW TECHNIQUES

Research Project

Project/Area Number 23406036
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Pediatrics
Research InstitutionNihon University

Principal Investigator

USHIJIMA Hiroshi  日本大学, 医学部, 客員教授 (10091068)

Co-Investigator(Renkei-kenkyūsha) OKITSU Shoko  東京大学, 医学系研究科, 客員研究員 (10082215)
TAKANASHI Sayaka  東京大学, 医学系研究科, 助教 (20645709)
Project Period (FY) 2011-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2014: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Keywordsアジア / 感染症 / 分子疫学 / 診断 / 海外協力 / 小児 / ウイルス / ノロウイルス / ロタウイルス
Outline of Final Research Achievements

We studied the molecular epidemiology of diarrheal viruses in children in Thailand, Bangladesh and Indonesia by using immunochromatograpy, multiplex RT-PCR and sequencing which we developed. Rotavirus was found mostly. That is different from Japan. New variants of norovirus were found to be spreading in the world. Saforld virus, cosavirus and bocavirus were detected in small numbers.
We diagnosed respiratory infections in Vietnam by genetic analyses. RS virus, rhinovirus and human parechovirus were common and some interesting results were recognized. Rubella infection was diagnosed genetically and still important disease in Vietnam.  In conclusion, virus infections of Asia linked Japan generally.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (120 results)

All 2015 2014 2013 2012 2011 Other

All Journal Article (73 results) (of which Peer Reviewed: 59 results,  Acknowledgement Compliant: 7 results) Presentation (41 results) (of which Invited: 4 results) Book (6 results)

  • [Journal Article] Application of the LAMP method for the detection of Campylobacter jejuni and C. coli from Thai children with diarrhea2015

    • Author(s)
      Pham NTK, Trinh QD, Khamrin P, Ukarapol N, Kongsricharoern T, Yamazaki W, Okitsu S, Maneekarn N, Hayakawa S, Ushijima H
    • Journal Title

      Japanese Journal of Infectious Diseases

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Molecular epidemiology of influenza A virus infection among hospitalized children in Vietnam during postpandemic period2015

    • Author(s)
      Tran DN, Pham TMH, Ha MT, Hayakawa S, Mizuguchi M, Ushijima H
    • Journal Title

      J Med Virol

      Volume: 印刷中 Issue: 6 Pages: 904-912

    • DOI

      10.1002/jmv.24143

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Detection and characterization of a novel human parechovirus genotype in Thailand2015

    • Author(s)
      Chuchaona W, Khamrin P, Yodmeeklin A, Saikruang W, Kongsricharoern T, Ukarapol N, Okitsu S, Hayakawa S, Ushijima H, Maneekarn N
    • Journal Title

      Infect Genet Evol

      Volume: 31 Pages: 300-304

    • DOI

      10.1016/j.meegid.2015.02.003

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Detection of diarrheal viruses circulating in adult patients in Thailand2014

    • Author(s)
      Saikruang W, Khamrin P, Suantai B, Okitsu S, Hayakawa S, Ushijima H, Maneekarn N
    • Journal Title

      Arch Virol

      Volume: 159(12) Issue: 12 Pages: 3371-3375

    • DOI

      10.1007/s00705-014-2191-3

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Molecular epidemiology of HIV in Asia2014

    • Author(s)
      Dey SK, Zahan N, Afrose S, Islam Q, Shajahan M, Saha S, Mahmud SA, Talukder AA, Mizuguchi M, Ushijima H
    • Journal Title

      HIV & AIDS Review

      Volume: 13 Pages: 33-39

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization of norovirus variants and genetic diversity of noroviruses and sapoviruses in Thailand2014

    • Author(s)
      Chaimongkol N, Khamrin P, Malasao R, Thongprachum A, Kongsricharoern T, Ukarapol N, Ushijima H, Maneekarn N
    • Journal Title

      J Med Virol

      Volume: 86(7) Issue: 7 Pages: 1210-1218

    • DOI

      10.1002/jmv.23781

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Human bocavirus in children with acute respiratory infections in Vietnam2014

    • Author(s)
      Tran DN, Nguyen TQ, Nguyen TA, Hayakawa S, Mizuguchi M, Ushijima H
    • Journal Title

      J Med Virol

      Volume: 86(6) Issue: 6 Pages: 988-994

    • DOI

      10.1002/jmv.23789

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Molecular detection and characterization of Aichivirus A in adult patients with diarrhea in Thailand2014

    • Author(s)
      Saikruang W, Khamrin P, Suantai B, Ushijima H, Maneekarn N
    • Journal Title

      J Med Virol

      Volume: 86(6) Issue: 6 Pages: 983-987

    • DOI

      10.1002/jmv.23904

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Epidemiology of human and animal kobuviruses2014

    • Author(s)
      Khamrin P, Maneekarn N, Okitsu S, Ushijima H
    • Journal Title

      Virus Disease

      Volume: 25(2) Issue: 2 Pages: 195-200

    • DOI

      10.1007/s13337-014-0200-5

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sensitive and rapid detection of Campylobacter species from stools of diarrheal children in Japan by LAMP method2014

    • Author(s)
      Ushijima H, Nishimura S, Thongprachum A, Shimizu-Onda Y, Tran DN, Pham NTK, Takanashi S, Dey SK, Okitsu S, Yamazaki W, Mizuguchi M, Hayakawa S
    • Journal Title

      Jap J Infect Dis

      Volume: 67 Pages: 374-378

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Detection and molecular characterization of human cosavirus in a pediatric patient with acute gastroenteritis, Japan2014

    • Author(s)
      Okitsu S, Khamrin P, Thongprachum A, Nishimura S, Kalesaran AFC, Takanashi S, Shimizu H, Hayakawa S, Mizuguchi M, Ushijima H
    • Journal Title

      Infect Genet Evol

      Volume: 28 Pages: 125-129

    • DOI

      10.1016/j.meegid.2014.09.019

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization and sequence analysis of the 2B region of Aichivirus C strains in Japan and Thailand2014

    • Author(s)
      Okitsu S, Khamrin P, Thongprachum A, Kalesaran AF, Takanashi S, Shimizu H, Maneekarn N, Mizuguchi M, Hayakawa S, Ushijima H
    • Journal Title

      Infect Genet Evol

      Volume: 26 Pages: 89-94

    • DOI

      10.1016/j.meegid.2014.05.010

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Norovirus and Foodborne Disease2014

    • Author(s)
      Ushijima H, Fujimoto T, Müller WEG, Hayakawa S
    • Journal Title

      Food Safety

      Volume: 2(3) Pages: 37-54

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Seroprevalence of chlamydophila pneumoniae in HIV-infected children in Vietnam2013

    • Author(s)
      Trinh QD, Pham NT, Le Nguyen NT, Lam BQ, Le Phan KT, Troonq KH, Le TQ, Nguyen HT, Tang TC, Izumi Y, Komine-Aizawa S, Ushijima H, Hayakawa S
    • Journal Title

      J Infect Chemother

      Volume: 19(3) Issue: 3 Pages: 538-541

    • DOI

      10.1007/s10156-012-0483-7

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Emergence of norovirusGII/4 2006a and 2006b variants in hospitalized children with acute gastroenteritis in Thailand2013

    • Author(s)
      Thongprachum A, Okitsu S, et al.
    • Journal Title

      Clin Lab

      Volume: 59(3+4) Issue: 03+04/2013 Pages: 271-276

    • DOI

      10.7754/clin.lab.2012.120316

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] complete genome sequenceanalysis of novel human bocavirus reveals genetic recombination between human bocavirus 2 and human bocavirus 4.2013

    • Author(s)
      Khamrin P, Okitsu S, et al.
    • Journal Title

      Infect Genet Evol

      Volume: 17 Pages: 132-136

    • DOI

      10.1016/j.meegid.2013.03.040

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Whole-genomic analysis of G3P[23], G9P[23] and G3P[13] rotavirus strains isolated from piglets with diarrhea in Thailand, 2006-20082013

    • Author(s)
      Okitsu S, et al.
    • Journal Title

      Infect. Genet. Evol

      Volume: 18 Pages: 74-86

    • DOI

      10.1016/j.meegid.2013.05.005

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アジアにおける下痢症ウイルスの分子疫学2013

    • Author(s)
      牛島廣治
    • Journal Title

      日大医学雑誌

      Volume: 72(3) Pages: 175-177

    • Related Report
      2013 Annual Research Report
  • [Journal Article] ノロウイルス下痢症、ウイルス性腸管感染症2013

    • Author(s)
      牛島廣治、沖津祥子
    • Journal Title

      臨床と微生物

      Volume: 40(2) Pages: 155-160

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Three clusters of Saffold virusescirculating in children with diarrhea in Japan2013

    • Author(s)
      Khamrin P, Okitsu S, et al.
    • Journal Title

      Infect Gent Evol

      Volume: 13 Pages: 339-343

    • DOI

      10.1016/j.meegid.2012.11.004

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular epidemiology and disease severity of human respiratory syncytial virus in Vietnam2013

    • Author(s)
      Tran DN
    • Journal Title

      PLOS One

      Volume: 8 Issue: 1 Pages: e45436-e45436

    • DOI

      10.1371/journal.pone.0045436

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome sequence of a novel virus of the species human adenovirus d associated with acute gastroenteritis.2013

    • Author(s)
      Matsushima Y
    • Journal Title

      Genome Announc.

      Volume: 1 Issue: 1

    • DOI

      10.1128/genomea.00068-12

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prevalence, seasonality, and peak age of infection of enteric adenoviruses in Japan, 1995-20092013

    • Author(s)
      Dey SK, Okitsu S, et al.
    • Journal Title

      Epidemiol Infect

      Volume: 141(5) Issue: 5 Pages: 958-60

    • DOI

      10.1017/s0950268812001586

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The virucidal effect against murine norovirus and feline calicivirus as surrogates for human norovirus by ethanol-based sanitilizers2013

    • Author(s)
      Shimizu-Onda Y
    • Journal Title

      J Infect Chemother

      Volume: - Issue: 4 Pages: 779-781

    • DOI

      10.1007/s10156-012-0516-2

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Complete genome sequence analysis of novel human bocavirus reveals genetic recombination between human bocavirus 2 and human bocavirus 42013

    • Author(s)
      Khamrin P
    • Journal Title

      Infect Genet Evol

      Volume: -

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ウイルス性胃腸炎の検査・診断2013

    • Author(s)
      沖津祥子
    • Journal Title

      臨床検査

      Volume: 57 Pages: 65-72

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Phylogenetic analysis of rubella viruses in Vietnam during 2009-20102012

    • Author(s)
      Tran DN
    • Journal Title

      J Med Virol

      Volume: 84 Issue: 4 Pages: 705-710

    • DOI

      10.1002/jmv.23199

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection and molecular characterization of cosavirus in adults with diarrhea, Thailand2012

    • Author(s)
      Khamrin P, Chaimongkol N, Malasao R, Suantai B, Saikhruang W, Kongsricharoern T, Ukarapol N, Okitsu S, Shimizu H, Hayakawa S, Ushijima H, Maneekarn N
    • Journal Title

      Virus Genes

      Volume: 44(2) Issue: 2 Pages: 244-246

    • DOI

      10.1007/s11262-011-0700-y

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sequence analysis of porcine kobuvirus VP1 region detected in pigs in Japan and Thailand2012

    • Author(s)
      Okitsu S, Khamrin P, Thongprachum A, Hidaka S, Kongkaew S, Kongkaew A, Maneekarn N, Mizuguchi M, Hayakawa S, Ushijima H
    • Journal Title

      Virus Genes

      Volume: 44(2) Issue: 2 Pages: 253-257

    • DOI

      10.1007/s11262-011-0692-7

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of base and codon usage by rubella virus2012

    • Author(s)
      Zhou Y
    • Journal Title

      Ach Virol

      Volume: (掲載確定)(印刷中) Issue: 5 Pages: 889-899

    • DOI

      10.1007/s00705-012-1243-9

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circulating of human bocavirus 1, 2, 3, and 4 in pediatric patients with acute gastroenteritis in Thailand2012

    • Author(s)
      Khamrin P
    • Journal Title

      Infect Genet Evol

      Volume: 12 Issue: 3 Pages: 565-569

    • DOI

      10.1016/j.meegid.2012.01.025

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Novel anti-HIV-1 activity produced by conjugating unsulfated dextran with polyL-lysine2012

    • Author(s)
      Nakamura K
    • Journal Title

      Antiviral Res

      Volume: 94 Issue: 1 Pages: 89-97

    • DOI

      10.1016/j.antiviral.2012.02.011

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of human bocavirus 1-4 from nasopharyngeal swab samples collected from patients with respiratory tract infections2012

    • Author(s)
      Koseki N
    • Journal Title

      J Clin Microbiol

      Volume: (掲載確定)(印刷中) Issue: 6 Pages: 2118-2121

    • DOI

      10.1128/jcm.00098-12

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of human bocavirus 1 and 2 from children with acute2012

    • Author(s)
      Khamrin P
    • Journal Title

      J Med Virol

      Volume: 84 Pages: 901-905

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Novel human adenovirus strains2012

    • Author(s)
      Matsushima Y, Shimizu H, Kano A, Nakajima E, Ishimaru Y, Dey SK, Watanabe Y, Adachi F, Suzuki K, Mitani K, Fujimoto T, Phan TG, Ushijima H
    • Journal Title

      Bangladesh. Emerg Infect Dis

      Volume: (in press) Issue: 5 Pages: 846-848

    • DOI

      10.3201/eid1805.111584

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genotypic linkages of gene segments of rotavirus circulating in pediatric patients with acute gastroenteritis in Thailand.2012

    • Author(s)
      Chaimongkol N
    • Journal Title

      Infect Genet Evol

      Volume: 12 Issue: 7 Pages: 1381-1391

    • DOI

      10.1016/j.meegid.2012.04.015

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Emergence of a new norovirus GII.6variant in Japan, 2008-20092012

    • Author(s)
      Chan-It W, Okitsu S, et al.
    • Journal Title

      J Med. Virol

      Volume: 84 Issue: 7 Pages: 1089-1096

    • DOI

      10.1002/jmv.23309

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation and comparison of the efficiency of immune-2012

    • Author(s)
      Thongprachum A
    • Journal Title

      Clin Lab

      Volume: 58 Pages: 489-493

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bio-cilica and bio-polyphosphate : applications in biomedince (bone formation)2012

    • Author(s)
      Wang X
    • Journal Title

      Curr Op in Biotechnol

      Volume: (掲載確定)(印刷中) Issue: 4 Pages: 570-578

    • DOI

      10.1016/j.copbio.2012.01.018

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic diversity and novel combinations of G4P[19] and G9P[19] porcine rotavirus strains in Thailand2012

    • Author(s)
      Saikruang W
    • Journal Title

      Vet Microbiol

      Volume: 161 Issue: 3-4 Pages: 255-262

    • DOI

      10.1016/j.vetmic.2012.07.036

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome sequence of an unusual human G10P[8] rotavirus2012

    • Author(s)
      Matsushima Y
    • Journal Title

      J Virol

      Volume: 86 Issue: 18 Pages: 10236-10237

    • DOI

      10.1128/jvi.01588-12

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Drug resistance mutations in the HIV-1 protease and reverse transcriptase genes in antiretroviral-naive Vietnamese children2012

    • Author(s)
      Trinh QD
    • Journal Title

      AIDS Res Hum Retroviruses

      Volume: (掲載確定)(印刷中) Issue: 10 Pages: 1305-1307

    • DOI

      10.1089/aid.2011.0280

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diversity of human astrovirus genotypes circulating in children with acute gastroenteritis in Thailand during 20001-20112012

    • Author(s)
      Malasao R
    • Journal Title

      J Med Virol,

      Volume: 84 Issue: 11 Pages: 1751-1756

    • DOI

      10.1002/jmv.23396

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Human adenovirus type 8 genome typing2012

    • Author(s)
      Adhikary AK
    • Journal Title

      J Med Microbiol

      Volume: 61 Issue: 11 Pages: 1491-1503

    • DOI

      10.1099/jmm.0.044172-0

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of immunochromatography, PCR and culture methods for the detection of campylobacter bacteria2012

    • Author(s)
      Dey SK
    • Journal Title

      J Microbiol Methods

      Volume: 91 Issue: 3 Pages: 566-568

    • DOI

      10.1016/j.mimet.2012.09.034

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transient heating of expressed breast milk up to 65℃ inactivates HIV-1 in milk: a simple, rapid, and cost-effective method to prevent postnatal transmission2012

    • Author(s)
      Hoque SA
    • Journal Title

      J Med Virol

      Volume: 85 Issue: 2 Pages: 187-193

    • DOI

      10.1002/jmv.23457

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reemergence of New Variant G3 Rotavirus in Japanese Pediatric Patients, 2009-20112012

    • Author(s)
      Thongprachum A
    • Journal Title

      Infect Genet Evol

      Volume: 13 Pages: 168-174

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 母乳栄養素の微量・短時間測定法としてのドライケミストリー法の有用性2012

    • Author(s)
      本間和宏
    • Journal Title

      日本健康医学会誌

      Volume: 21 Pages: 101-104

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ノロウイルス2012

    • Author(s)
      牛島廣治
    • Journal Title

      小児科臨床 (増刊号)

      Volume: 65 Pages: 1369-1374

    • Related Report
      2012 Annual Research Report
  • [Journal Article] ノロウイルス感染症2012

    • Author(s)
      牛島廣治
    • Journal Title

      小児内科

      Volume: 44 Pages: 356-357

    • Related Report
      2012 Annual Research Report
  • [Journal Article] ノロウイルス感染症の現状と対策2012

    • Author(s)
      牛島廣治
    • Journal Title

      小児内科

      Volume: 44 Pages: 1150-1150

    • Related Report
      2012 Annual Research Report
  • [Journal Article] ノロ、ロタ、ピコルナウイルス2012

    • Author(s)
      沖津祥子
    • Journal Title

      臨床と微生物

      Volume: 39 Pages: 677-684

    • Related Report
      2012 Annual Research Report
  • [Journal Article] ノロウイルス診断法の最近の知見2012

    • Author(s)
      牛島廣治
    • Journal Title

      小児科臨床

      Volume: 65 Pages: 2577-2582

    • Related Report
      2012 Annual Research Report
  • [Journal Article] A wide variety of diarrheal viruses circulating in pediatric patients in Thailand2012

    • Author(s)
      Chaimongkol N
    • Journal Title

      Clin Lab

      Volume: 58 Pages: 117-123

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Use of multilocus variable-number tandem repeat analysis in molecular subtyping of Salmonella enterica serovar Typhi isolates2012

    • Author(s)
      Tien YY
    • Journal Title

      J Med Microbiol

      Volume: 61 Issue: 2 Pages: 223-232

    • DOI

      10.1099/jmm.0.037291-0

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation and comparison of the efficiency of immunochromatography methods for Norovirus detection2012

    • Author(s)
      Thongprachum A
    • Journal Title

      Clin Lab

      Volume: (掲載確定)(印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection and geneticcharacterization of rotavirus infections in non-hospitalized children with acute gastroenteritis in Japan, 2007-2009.2011

    • Author(s)
      Chan-it, W, Okitsu S, et al.
    • Journal Title

      Infect Genet Evol

      Volume: 11 Issue: 2 Pages: 415-422

    • DOI

      10.1016/j.meegid.2010.11.018

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 加熱処理による母乳中のマウスノロウイルスの不活化効果2011

    • Author(s)
      清水優子
    • Journal Title

      環境感染誌

      Volume: 26 Pages: 79-81

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A single-tube multiplex PCR for rapid detection of 10 diarrheal viruses in stool samples collected from children with diarrhea2011

    • Author(s)
      Khamrin P
    • Journal Title

      J Virol Methods

      Volume: 173 Issue: 2 Pages: 390-393

    • DOI

      10.1016/j.jviromet.2011.02.012

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic diversity and emergence of norovirus GII/4-2006b in Japan during 2006-20072011

    • Author(s)
      Dey SK
    • Journal Title

      Clin Lab

      Volume: 57 Pages: 193-199

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection and genetic characterization of norovirus infection in children with acute gastroenteritis in Japan, 2007-20092011

    • Author(s)
      Chan-it W
    • Journal Title

      Clin Lab

      Volume: 57 Pages: 213-220

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Seroprevalence of rubella and measles antibodies in Lao PDR2011

    • Author(s)
      Phengxay M
    • Journal Title

      Clin Lab, 2011 ; (3+4)

      Volume: 57 Pages: 234-244

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Saffold cardioviruses in children with diarrhea, Thailand.2011

    • Author(s)
      Khamrin P, Chaimongkol N, Nantachit N, Okitsu S, Ushijima H, Maneekarn N
    • Journal Title

      Emerg Infect Dis

      Volume: 17 Issue: 6 Pages: 1150-1152

    • DOI

      10.3201/eid1706.101983

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Viral Molecular Characterization of the First Congenital Rubella Syndrome Case in Vietnam2011

    • Author(s)
      Tran DN
    • Journal Title

      Clin Lab

      Volume: 57 Pages: 397-401

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of the rapid methods for screening of group A rotavirus in stool samples2011

    • Author(s)
      Khamrin P
    • Journal Title

      J Trop Pediatr

      Volume: 57 Issue: 5 Pages: 375-377

    • DOI

      10.1093/tropej/fmq101

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genomic characterization of a novel human adenovirus type 31 recombinant in the hexon gene2011

    • Author(s)
      Matsushima Y, Shimizu H, Phan TG, Ushijima H
    • Journal Title

      J Gen Virol

      Volume: 92(12) Issue: 12 Pages: 2770-2775

    • DOI

      10.1099/vir.0.034744-0

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Seasonal pattern and genotype distribution of sapovirus infection in Japan, 2003-20092011

    • Author(s)
      Dey SK, Phathammavong O, Nguyen TD, Thongprachum A, Chanit W, Okitsu S, Mizuguchi M, Ushijima H
    • Journal Title

      Epidemiol Infect 2012 Jan

      Volume: 140(1) Issue: 1 Pages: 74-77

    • DOI

      10.1017/s0950268811000240

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ウイルスによる消化管障害ノロウイルス2011

    • Author(s)
      牛島廣治
    • Journal Title

      臨床消化器内科

      Volume: 26 Pages: 1003-1010

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 子どもの感染症に対するあぷろ-ちの仕方消化器感染症に対するアプローチ2011

    • Author(s)
      牛島廣治
    • Journal Title

      小児科学レクチャー

      Volume: 2 Pages: 233-240

    • Related Report
      2011 Annual Research Report
  • [Journal Article] ノロウイルス感染と予防指針2011

    • Author(s)
      田中智之
    • Journal Title

      臨床とウイルス

      Volume: 39 Pages: 155-160

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 感染性胃腸炎(ロタウイルス・ノロウイルス)2011

    • Author(s)
      牛島廣治
    • Journal Title

      こどもケア

      Volume: 6 Pages: 31-35

    • Related Report
      2011 Annual Research Report
  • [Journal Article] カリシウイルス2011

    • Author(s)
      牛島廣治
    • Journal Title

      ウイルス

      Volume: 61 Pages: 193-203

    • NAID

      10030577996

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Molecular epidemiology of human and animal kobuvirus2011

    • Author(s)
      Khamrin P
    • Journal Title

      臨床とウイルス

      Volume: 36 Pages: 147-154

    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecular epidemiology of circulating rotavirus in hospitalized acute gastroenteritis children, in North Sulawesi, Indonesia2014

    • Author(s)
      Angela Kalesaran、Aksara Thongprachum、高梨さやか、沖津祥子、早川智、牛島廣治
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜 会議センター (神奈川県横浜市)
    • Year and Date
      2014-11-10 – 2014-11-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Circulating rotavirus in hospitalized pediatric patients, with the predominance of G1P[8]DS-1-like human rotavirus in Manado, Indonesia2014

    • Author(s)
      Kalesaran AFC, Thongprachum A, Pangemanan DHC, Takanashi S, Okitsu S, Hayakawa S, Warouw SM, Mizuguchi M, Ushijima H
    • Organizer
      International Meeting on Emerging Diseases and Suiveillance
    • Place of Presentation
      Hilton Vienna (オーストリア、ウイーン市).
    • Year and Date
      2014-10-31 – 2014-11-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] Molecular detection of diarrheal viruses associated with acute gastroenteritis in pediatric patients in Indonesia2014

    • Author(s)
      Kalesaran Angela, Thongprachum Aksara, 高梨さやか、沖津祥子、Pangemanan H. C. Damajanty, Warow M. Sarah, 早川智、水口雅、牛島廣治
    • Organizer
      第46回日本小児感染症学会学術集会
    • Place of Presentation
      京王プラザホテル (東京都新宿区)
    • Year and Date
      2014-10-18 – 2014-10-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] バングラデシュにおける下痢原性微生物の疫学調査と迅速診断薬の評価2014

    • Author(s)
      高梨さやか、Shuvra Kanti Dey, Najmuj Sakib, Aksara Thongprachum, Angela Kalesaran, 井上茉南、沖津祥子、水口雅、牛島廣治
    • Organizer
      第46回日本小児感染症学会学術集会
    • Place of Presentation
      京王プラザホテル (東京都新宿区)
    • Year and Date
      2014-10-18 – 2014-10-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Recent trend of diarrheal viruses in Japan2014

    • Author(s)
      Ushijima H, Takanashi S, Thongprachum A, Khamrin P, Okitsu S, Mizuguchi M, Hayakawa S
    • Organizer
      The 10th China-Japan International Conference of Virology
    • Place of Presentation
      Xinmin Hotel(中国長春)
    • Year and Date
      2014-08-26 – 2014-08-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Detection of cosavirus in porcine stool samples in Thailand2014

    • Author(s)
      Okitsu S, Khamrin P, Thongprachum A, Takanashi S, Hayakawa S, Manee, karn N, Miuzguchi M, Ushijima H
    • Organizer
      The 10th China-Japan International Conference of Virology
    • Place of Presentation
      Xinmin Hotel(中国長春)
    • Year and Date
      2014-08-26 – 2014-08-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Emergence of new norovirus variants and genotype diversity of noroviruses and sapoviruses in Thailand2013

    • Author(s)
      Khamrin P, Chaimongkol N, Malasad R, Thongprachum A, Kongsricharoern T, Ukarapol N, Ushijima H, Maneekarn N
    • Organizer
      5th International Conference on caliciviruses
    • Place of Presentation
      前門建国飯店(中国北京市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Genetic characterization of human influenza A viruses in Vietnam from 2010 to 20112013

    • Author(s)
      Tran N, 高梨さやか、沖津祥子、早川智、水口雅、牛島廣治
    • Organizer
      第45回日本小児感染症学総会・集会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] LAMP,PCRおよび培養法を用いた小児下痢便からのカンピロバクターの検出2013

    • Author(s)
      牛島廣治、西村修一、Thongpachum A, Tran DN, Pham NK, 高梨さやか、沖津祥子、水口雅、早川智
    • Organizer
      第45回日本小児感染症学総会・集会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] タイのブタから検出されたporcine kobuvirus 1株の全長配列の決定、およびタイ、日本の株における2B領域の解析2013

    • Author(s)
      沖津祥子、Khamrin P, Thongprachum A, 高梨さやか、 早川智、牛島廣治
    • Organizer
      第61回日本ウイルス学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Human rhinovirus infections in hospitalized children in Vietnam2013

    • Author(s)
      Tran DN, 高梨さやか、 沖津祥子、 Nguyen TQN, Ha MT, Tran TTL, 水口 雅、早川智、牛島廣治
    • Organizer
      第61回日本ウイルス学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] RT-LAMP法を用いた蚊からのアルボウイルスゲノムの迅速検出2012

    • Author(s)
      江下優樹
    • Organizer
      第64回日本衛生動物学会大会
    • Place of Presentation
      信州大学繊維学部(長野県上田市)
    • Year and Date
      2012-03-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] Novel picornaviruses in children and adults with diarrhea, Thailand2012

    • Author(s)
      Khamrin P
    • Organizer
      第8回日本小児消化管感染症研究会
    • Place of Presentation
      日本教育会館(東京都千代田区)
    • Year and Date
      2012-02-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecular epidemiological trend of diarrheal virus infections in Japanese pediatric patients, 2009-20112012

    • Author(s)
      Thongprachum A
    • Organizer
      第8回日本小児消化管感染症研究会
    • Place of Presentation
      日本教育会館(東京都千代田区)
    • Year and Date
      2012-02-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] ラオス、ビエンチャン市における妊娠可能年齢女子の風疹抗体保有状況2011

    • Author(s)
      駒瀬勝啓
    • Organizer
      第15回日本ワクチン学会学術集会
    • Place of Presentation
      日本教育会館(東京都千代田区)
    • Year and Date
      2011-12-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新たな視点からのウイルス性下痢症の動向2011

    • Author(s)
      牛島廣治
    • Organizer
      富山県小児科医会
    • Place of Presentation
      ANAクラウンプラザホテル富山(富山県富山市)(招待講演)
    • Year and Date
      2011-12-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecular epidemiology of diarrheal viruses circulating in Pediatric patients in Japan, 2009-20102011

    • Author(s)
      Thongprachum A
    • Organizer
      第42回日本小児感染症学会総会・学術集会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Year and Date
      2011-10-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] Viral etiology of acute respiratory infections in hospitalized children at Ho Chi Minh City2011

    • Author(s)
      Tran DN
    • Organizer
      第42回日本小児感染症学会総会・学術集会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Year and Date
      2011-10-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 食品を介する感染症のKAP調査1.食肉の生食に関するKAP調査(1大学および1小学校)2011

    • Author(s)
      牛島廣治
    • Organizer
      第42回日本小児感染症学会総会・学術集会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Year and Date
      2011-10-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] ノロウイルス・イムノクロマトキットの改良による母乳、新生児便の偽陽性の減少2011

    • Author(s)
      牛島廣治
    • Organizer
      第26回日本母乳哺育学会・学術集会
    • Place of Presentation
      広尾ホール(東京都渋谷区)
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] RT-multiplex PCR for detection of diarrheal viruses2011

    • Author(s)
      Ushijima H
    • Organizer
      XV International Congress of Virology
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Saffold cardioviruses in pediatric patients with diarrhea, Thailand2011

    • Author(s)
      Khamrin P
    • Organizer
      XV International Congress of Virology
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecular characterization of VP1 region of porcine kobuvirus2011

    • Author(s)
      Okitsu S
    • Organizer
      XV International Congress of Virology
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] ウイルス性下痢症の最近の話題

    • Author(s)
      牛島廣治
    • Organizer
      第23回城北成育医療研究会
    • Place of Presentation
      メトロポリタンホテル(池袋)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ウイルス性下痢症の最近の話題

    • Author(s)
      牛島廣治
    • Organizer
      520回医学研修の日 日本医師会横浜市支部会
    • Place of Presentation
      横浜市健康福祉総合センターホール
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] ウイルス性下痢症の最近の動向~ロタウイルスワクチンを含めて~

    • Author(s)
      牛島廣治
    • Organizer
      地域連携集会 Meet the experts
    • Place of Presentation
      東邦大学(東京都)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] タイ国の健康なブタ血清中のブタコブウイルス

    • Author(s)
      沖津祥子
    • Organizer
      第53回日本臨床ウイルス学会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Molecular characterization of human bocavirus isolated from children with acute gastroenteritis in Japan and Thailand

    • Author(s)
      Khamrin P
    • Organizer
      The 9th Japan-China International Conference of Virology
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Full genome analysis of rotavirus P[23] colleted from piglets with diarrhea in Thailand, 2006-2008

    • Author(s)
      Okitsu S
    • Organizer
      The 9th Japna-China International Conference of Virology
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Novel picornaviruses in children and adults with diarrhea, Thailand

    • Author(s)
      Ushijima H
    • Organizer
      The 9th Japna-China International Conference of Virology
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] アジアにおける腸管ウイルス感染

    • Author(s)
      牛島廣治
    • Organizer
      日本大学講演会
    • Place of Presentation
      JICA地球ひろば(東京都)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] ウイルス性下痢症研究の過去・現在・未来 -私達の研究を含めて-

    • Author(s)
      牛島廣治
    • Organizer
      平成24年度群馬県感染症研修会
    • Place of Presentation
      群馬県立県民健康科学大学(群馬県)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Picornaviruses associated with gastroenteritis in Japan and Thailand.

    • Author(s)
      Thongprachum A
    • Organizer
      The 16th Annual meeting of Japanese Society for Neurovirology
    • Place of Presentation
      国立感染症研究所(東京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Reemergence of variant G3 rotavirus in Japanese pediatric patients

    • Author(s)
      Thongprachum A
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      グランキューブ大阪(大阪府)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Human bocavirus in children with respiratory infections in Vietnam

    • Author(s)
      トラン グエン
    • Organizer
      第44回日本小児感染症学会総会・学術集会
    • Place of Presentation
      西日本総合展示場・北九州国際会議場(福岡県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Molecular epidemiology trend of diarrheal viruses circulating in Japanese pediatric patients, 2010-2011.

    • Author(s)
      Thongprachum, A
    • Organizer
      第44回日本小児感染症学会総会・学術集会
    • Place of Presentation
      西日本総合展示場・北九州国際会議場(福岡県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ロタウイルスワクチン導入移行期における同ウイルスのG遺伝子型の検討

    • Author(s)
      高梨さやか
    • Organizer
      第9回日本小児消化管感染症研究会・学術集会
    • Place of Presentation
      北浜フォーラム(大阪府)
    • Related Report
      2012 Annual Research Report
  • [Presentation] LAMP法など遺伝子診断法によるカンピロバクターの診断-細菌培養との比較-

    • Author(s)
      牛島廣治
    • Organizer
      第9回日本小児消化管感染症研究会・学術集会
    • Place of Presentation
      北浜フォーラム(大阪府)
    • Related Report
      2012 Annual Research Report
  • [Presentation] The emergence of norovirus GII/4 2012 outbreak in Japanese pediatric patients

    • Author(s)
      Thongprachum A
    • Organizer
      第9回日本小児消化管感染症研究会・学術集会
    • Place of Presentation
      北浜フォーラム(大阪府)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ヒトノロウイルスの代替としてネコカリシウイルスおよびマウスノロウイルスを用いたアルコール製剤の不活化効果

    • Author(s)
      赤阪天平
    • Organizer
      第28回日本環境感染症学総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 保育園児におけるインフルエンザ予防接種の接種率と接種率に関連する要因

    • Author(s)
      牛島廣治
    • Organizer
      第4回予防接種に関する研究報告会
    • Place of Presentation
      予防接種リサーチセンター(東京都)
    • Related Report
      2012 Annual Research Report
  • [Book] Chapter 11. Emerging foodborne pathogenic kobuvirus, picobirnavirus, and torovirus. “Foodborne Viral Pathogens”2015

    • Author(s)
      Pattara Khamrin, Niwat Maneekarn, Shoko Okitsu, Hiroshi Ushijima
    • Publisher
      CRC press
    • Related Report
      2014 Annual Research Report
  • [Book] Emerging foodborne pathogenic kobuvirus, picobirnavirus, and torovirus  “Foodborne Viral Pathogens”2015

    • Author(s)
      Pattara Khamrin, Niwat Maneekarn, Shoko Okitsu, Hiroshi Ushijima
    • Publisher
      CRC Press
    • Related Report
      2013 Annual Research Report
  • [Book] Springer2012

    • Author(s)
      Luibai Li
    • Publisher
      Handbook of Anthropometry: Physical Measures of Human Form in Health and Disease
    • Related Report
      2012 Annual Research Report
  • [Book] 小児感染症学改訂第2版2011

    • Author(s)
      岡部信彦
    • Publisher
      診断と治療社
    • Related Report
      2011 Annual Research Report
  • [Book] ウイルス感染症の検査・診断スタンダード2011

    • Author(s)
      田代眞人
    • Total Pages
      446
    • Publisher
      羊土社
    • Related Report
      2011 Annual Research Report
  • [Book] ロタウイルス胃腸炎の予防と治療の新しい展開2011

    • Author(s)
      牛島廣治
    • Publisher
      医薬ジャーナル社
    • Related Report
      2011 Annual Research Report

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Published: 2011-04-06   Modified: 2019-07-29  

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