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Cognitive science on individual difference of impulsive behavior

Research Project

Project/Area Number 23500329
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cognitive science
Research InstitutionKyoto University

Principal Investigator

NOMURA Michio  京都大学, 教育学研究科(研究院), 准教授 (60399011)

Co-Investigator(Renkei-kenkyūsha) NOMURA Yasuyuki  横浜薬科大学, 薬学部, 教授 (00034041)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords衝動性 / 運動反応制御 / セロトニン / 遺伝子 / 個人差 / 前頭前野 / 自己制御 / 反応競合 / 遺伝子多型 / tDCS / 報酬・罰 / セロトニン神経系 / 運動反応 / 報酬 / 罰 / ドパミン
Research Abstract

Present study focuses on these interrelated areas through the lens of the serotonin transporter (5-HTT), looking specifically at the impulsivity in Japanese people. A large number of behavioral genetics studies have demonstrated that individuals carrying the less efficient S allele of the 5-HTTLPR gene have an increased susceptibility to emotion disorders, whereas this risk is much lower in collectivistic societies. A new hypothesis of gene-environment interaction proposed here addresses this mechanism by showing the following: (1) the behavioral regulation of S allele carriers impulsivity is optimized under aversive conditions, which may help them to adapt to collectivistic cultures; and (2) such self-regulatory responses underlied by the prefrontal cortex are modulated by cultural interdependent self-construal and psychosocial factors, such as general trust, all of which are geared toward modulating fear and social pain, and thus may lower the risk for impulsive behavior.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (48 results)

All 2014 2013 2012 2011 2010 Other

All Journal Article (13 results) (of which Peer Reviewed: 12 results) Presentation (18 results) (of which Invited: 4 results) Book (16 results) Remarks (1 results)

  • [Journal Article] Beautiful Faces Enhance Verbal Working Memory Performance: An NIRS Study.2014

    • Author(s)
      Kajimura, S., Himichi, T., & Nomura, M.
    • Journal Title

      Psychologia: An International Journal of Psychological Sciences.

      Volume: .

    • NAID

      130003391457

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-conscious neural regulation against mortality concerns.2013

    • Author(s)
      Yanagisawa, K., Kashima. E. S., Moriya. H., Masui, K., Furutani, K., Nomura. M., Yoshida, H., & Ura, M.
    • Journal Title

      Neuroscience Letters

      Volume: 552 Pages: 35-39

    • DOI

      10.1016/j.neulet.2013.07.027

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] COMT Val 158 Met influences the perception of other's pain2012

    • Author(s)
      Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M
    • Journal Title

      Psychology Research

      Volume: 2 Pages: 185-195

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] COMT Val 158 Met influences the perception of other's pain.2012

    • Author(s)
      Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M.
    • Journal Title

      Psychology Research

      Volume: 2 Pages: 185-195

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] The interplay of genetic and environmental influences on prefrontal function and self-regulation of impulsivity2011

    • Author(s)
      Nomura, M
    • Journal Title

      Psychologia : An International Journal of Psychological Sciences

      Volume: 54 Pages: 241-251

    • NAID

      130001896344

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Amount of altruistic punishment accounts for subsequent emotional gratification in participants with primary psychopathy2011

    • Author(s)
      Masui, K., Iriguchi, S., Nomura, M., Ura, M
    • Journal Title

      Personality and Individual Differences

      Volume: 51 Pages: 823-828

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of the behavioral inhibition and activation systems on social inclusion and exclusion2011

    • Author(s)
      Yanagisawa, K., Masui, K., Onoda, K., Furutani, K., Nomura, M., Ura, M., Yoshida, H
    • Journal Title

      Journal of Experimental Social Psychology

      Volume: 47 Pages: 502-505

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of reward and punishment on response inhibition in non-clinical psychopathy2011

    • Author(s)
      Masui, K., Nomura, M
    • Journal Title

      Personality and Individual Differences

      Volume: 50 Pages: 69-73

    • NAID

      120002753740

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Does higher general trust serve as a psychosocial buffer against social pain? : A NIRS study of social exclusion2011

    • Author(s)
      Yanagisawa, K., Masui, K., Furutani, K., Nomura, M., Ura, M., Yoshida, H
    • Journal Title

      Social Neuroscience

      Volume: 6 Pages: 377-387

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The interplay of genetic and environmental influences on prefrontal function and self-regulation of impulsivity2011

    • Author(s)
      Nomura, M.
    • Journal Title

      Psychologia: An International Journal of Psychological Sciences

      Volume: 54 Pages: 241-151

    • NAID

      130001896344

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Perspective taking associated with social relationships : A NIRS study2010

    • Author(s)
      Nomura, Y., Ogawa, T., Nomura, M
    • Journal Title

      Neuroreport

      Volume: 21 Pages: 1100-1105

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 衝動性の基盤となる構成概念, 脳, 遺伝子多型について-Stop Signal Paradaigm の観点より-2010

    • Author(s)
      増井啓太・野村理朗
    • Journal Title

      感情心理学研究

      Volume: 18 Pages: 15-24

    • Related Report
      2013 Final Research Report
  • [Journal Article] Beautiful Faces Enhance Verbal Working Memory Performance : An NIRS Study

    • Author(s)
      Kajimura, S., Himichi, T., & Nomura, M
    • Journal Title

      Psychologia : An International Journal of Psychological Sciences

      Volume: (in press)

    • NAID

      130003391457

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] Envy decreases attention to sadness.2014

    • Author(s)
      Fujita, H., Himichi, T., & Nomura, M.
    • Organizer
      The 15th Annual Meeting of Society for Personality and Social Psychology.
    • Place of Presentation
      San diego, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Genes, brain and culture through a 5-HTT lens2013

    • Author(s)
      Nomura, M
    • Organizer
      International Cultural Neuroscience Consortium Conference
    • Place of Presentation
      Evanston, U.S
    • Year and Date
      2013-05-11
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Genes, brain and culture through a 5-HTT lens.2013

    • Author(s)
      Nomura, M.
    • Organizer
      nternational Cultural Neuroscience Consortium Conference.
    • Place of Presentation
      Evanston, U.SA
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 日常的な失敗傾向の背景要因に関する検討.2013

    • Author(s)
      梶村昇吾・野村理朗.
    • Organizer
      日本心理学会第77回大会
    • Place of Presentation
      北海道医療大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] 妬み情動が注意バイアスに及ぼす影響―空間手がかり課題及びfNIRSを用いた認知神経科学的検討―.2013

    • Author(s)
      藤田弥世・日道俊之・野村理朗
    • Organizer
      日本心理学会第77回大会
    • Place of Presentation
      北海道医療大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] 心的ストレスが他者の心的状態の推測へ及ぼす影響 ―fNIRSを用いた認知神経科学的検討―.2013

    • Author(s)
      日道俊之・藤田弥世・野村理朗
    • Organizer
      日本心理学会第77回大会
    • Place of Presentation
      北海道医療大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] Attractive faces enhance cognitive performance2012

    • Author(s)
      Kajimura, S., Himichi, T., Nomura, M
    • Organizer
      43rd NIPS International Symposium
    • Place of Presentation
      Okazaki, Japan
    • Related Report
      2013 Final Research Report
  • [Presentation] Involvement of a polymorphism in the 5-HTT gene in impulsive response style in Japanese population2012

    • Author(s)
      Nomura, M., Kaneko, M., Kusumi, I., Canli, T., Koyama, T., Nomura, Y
    • Organizer
      28th World Congress of Collegium Internationale Neuro-Psychopharmacologium (CINP)
    • Place of Presentation
      Stockholm, Sweden
    • Related Report
      2013 Final Research Report
  • [Presentation] Involvement of the 5-HT2A receptor gene polymorphism in trait anxiety, in activity of VLPFC and in impulsivity : a NIRS study2012

    • Author(s)
      Kajimura, S., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M
    • Organizer
      28th World Congress of Collegium Internationale Neuro-Psychopharmacologium (CINP)
    • Place of Presentation
      Stockholm, Sweden
    • Related Report
      2013 Final Research Report
  • [Presentation] Biological and psychological basis of impulsive behavior. The 32nd Naito Conference2011

    • Author(s)
      Nomura, M
    • Organizer
      Biological basis of mental functions and disorders
    • Place of Presentation
      Yamanashi
    • Year and Date
      2011-10-21
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] The interplay of genetic and environmental influences on prefrontal function and self-regulation of impulsivity2011

    • Author(s)
      Nomura, M
    • Organizer
      International symposium "Towards an empirical understanding of cultural, social and evolutionary perspectives in psychological science"
    • Place of Presentation
      Lancaster. U. K
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] COMT Val158Met gene polymorphism influences the perception of others pain2011

    • Author(s)
      Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M
    • Organizer
      Clinical psychopharmacology and neuroscience, 2011, 9, P137. 2th Asian College of Neuropsychopharmacology
    • Place of Presentation
      Seoul, Korea
    • Related Report
      2013 Final Research Report
  • [Presentation] COMT Val 158 Met polymorphism modulates impulsivity-related human behavior2011

    • Author(s)
      Nomura, M., Kondo, M. H., Kashino, M
    • Organizer
      The International College of Neuropsychopharmacology, 1st IBRO MIDDLE EAST NEUROSCIENCE CONFERENCE
    • Place of Presentation
      Al Ain, UAE
    • Related Report
      2013 Final Research Report
  • [Presentation] COMT Val158Met gene polymorphism influences the perception of others pain.2011

    • Author(s)
      Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M.
    • Organizer
      2th Asian College of Neuropsychopharmacology
    • Place of Presentation
      Seoul
    • Related Report
      2011 Research-status Report
  • [Presentation] The relationship between response disinhibition and rVLPFC deactivation in psychopathic participants : A near-infrared spectroscopy study2010

    • Author(s)
      Masui, K., Nomura, M
    • Organizer
      50th Annual Meeting of Society for Psychophysiological Research
    • Place of Presentation
      Portland, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Impulsivity-related human prefrontal brain activation during Go/No-go task is moderated by COMT Val 158 Met polymorphism : a fMRI study2010

    • Author(s)
      Nomura, M., Kondo, M. H., Kashino, M
    • Organizer
      The International College of Neuropsychopharmacology
    • Place of Presentation
      Honkong, China
    • Related Report
      2013 Final Research Report
  • [Presentation] Involvement of a polymorphism in the 5-HTT gene in impulsive response style in Japanese population

    • Author(s)
      Nomura, M., Kaneko, M., Kusumi, I.,
    • Organizer
      Internationale Neuro-Psychopharmacologium (CINP)
    • Place of Presentation
      Stockholm
    • Related Report
      2012 Research-status Report
  • [Presentation] Involvement of the 5-HT2A receptor gene polymorphism in trait anxiety, in activity of VLPFC and in impulsivity: a NIRS study

    • Author(s)
      Kajimura, S., Kaneko, M., Nomura, J., Canli, T., Koyama, T., Nomura, Y.
    • Organizer
      Internationale Neuro-Psychopharmacologium (CINP)
    • Place of Presentation
      Stockholm
    • Related Report
      2012 Research-status Report
  • [Book] 青年期発達百科事典(第三巻「嗜癖」「ギャンブル」「アルコール摂取」「精神薬理学」「リスクテイキング行動」「喫煙」). 子安増生・二宮克美(監訳)丸善出版. (原書 : Brown, B. B. & Prinstein, M. J. (Ed.)2014

    • Author(s)
      野村理朗(編集)
    • Publisher
      Encyclopedia of Adolescence. Academic Press
    • Related Report
      2013 Final Research Report
  • [Book] 脳とこころ 唐沢かおり(編)「新社会心理学 -心と社会をつなぐ知の統合-」2014

    • Author(s)
      野村理朗
    • Publisher
      北大路書房
    • Related Report
      2013 Final Research Report
  • [Book] Genes, brain and culture through a 5-HTT lens. In Chiao, J, Shu-Chen, Rebecca, Bob (eds.), Handbook of Cultural Neuroscience: Cultural Neuroscience and Health.2014

    • Author(s)
      Nomura, M.
    • Publisher
      Oxford University Press
    • Related Report
      2013 Annual Research Report
  • [Book] 青年期発達百科事典(第三巻「嗜癖」「ギャンブル」「アルコール摂取」「精神薬理学」「リスクテイキング行動」「喫煙」).子安増生・二宮克美(監訳)2014

    • Author(s)
      野村理朗
    • Publisher
      丸善出版
    • Related Report
      2013 Annual Research Report
  • [Book] 脳とこころ 唐沢かおり(編)「新社会心理学 -心と社会をつなぐ知の統合-」2014

    • Author(s)
      野村理朗
    • Total Pages
      15
    • Publisher
      北大路書房
    • Related Report
      2013 Annual Research Report
  • [Book] 情動 田中啓治・御子柴克彦(編)「脳科学辞典」2014

    • Author(s)
      野村理朗
    • Publisher
      脳科学辞典編集委員会
    • Related Report
      2013 Annual Research Report
  • [Book] Using NIRS to investigate social relationship in empathic process. "Infrared Spectroscopy - Life and Biomedical Sciences"2012

    • Author(s)
      Ogawa, T., Nomura, M
    • Publisher
      InTech
    • Related Report
      2013 Final Research Report
  • [Book] Psychopathy, Reward, and Punishment. (Eds.) Michela Balconi. "The Psychology of Reward"2012

    • Author(s)
      Masui, K., Nomura, M., Ura, M
    • Publisher
      Nova Science Publishers
    • Related Report
      2013 Final Research Report
  • [Book] Using NIRS to investigate social relationship in empathic process.2012

    • Author(s)
      Ogawa, T., Nomura, M
    • Total Pages
      12
    • Publisher
      InTech
    • Related Report
      2012 Research-status Report
  • [Book] Psychopathy, Reward, and Punishment. "The Psychology of Reward"2012

    • Author(s)
      Masui, K., Nomura, M., Ura, M.
    • Total Pages
      32
    • Publisher
      Nova Science Publishers
    • Related Report
      2012 Research-status Report
  • [Book] Nova Science Publishers2012

    • Author(s)
      Masui, K., Nomura, M., Ura, M.
    • Publisher
      Psychopathy, Reward, and Punishment. "The Psychology of Reward"
    • Related Report
      2011 Research-status Report
  • [Book] 衝動性 廣中直行(編)「「心理学研究法」 学習・動機・情動」2011

    • Author(s)
      野村理朗
    • Publisher
      誠心書房
    • Related Report
      2013 Final Research Report
  • [Book] ニューロイメージング 子安増生・二宮克美(編)「キーワードコレクション・認知心理学」2011

    • Author(s)
      野村理朗
    • Publisher
      新曜社
    • Related Report
      2013 Final Research Report
  • [Book] 衝動性 子安増生・二宮克美(編)「キーワードコレクション・認知心理学」2011

    • Author(s)
      野村理朗
    • Publisher
      新曜社
    • Related Report
      2013 Final Research Report
  • [Book] 「心理学研究法」 学習・動機・情動2011

    • Author(s)
      野村理朗
    • Publisher
      誠心書房
    • Related Report
      2011 Research-status Report
  • [Book] Genes, brain and culture through a 5-HTT lens. In Chiao, J, Shu-Chen, Rebecca, Bob (eds.), Handbook of Cultural Neuroscience : Cultural Neuroscience and Health

    • Author(s)
      Honkong, China
    • Publisher
      New York : Oxford University Press(in press)
    • Related Report
      2013 Final Research Report
  • [Remarks]

    • URL

      http://www.researchgate.net/profile/Michio_Nomura

    • Related Report
      2013 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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