| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
Present study focuses on these interrelated areas through the lens of the serotonin transporter (5-HTT), looking specifically at the impulsivity in Japanese people. A large number of behavioral genetics studies have demonstrated that individuals carrying the less efficient S allele of the 5-HTTLPR gene have an increased susceptibility to emotion disorders, whereas this risk is much lower in collectivistic societies. A new hypothesis of gene-environment interaction proposed here addresses this mechanism by showing the following: (1) the behavioral regulation of S allele carriers impulsivity is optimized under aversive conditions, which may help them to adapt to collectivistic cultures; and (2) such self-regulatory responses underlied by the prefrontal cortex are modulated by cultural interdependent self-construal and psychosocial factors, such as general trust, all of which are geared toward modulating fear and social pain, and thus may lower the risk for impulsive behavior.
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