Central neuromodulators and decision making
| Project/Area Number |
23500393
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neuroscience in general
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | ドパミン / アセチルコリン / 報酬 / 空間性注意 / 意思決定 / 半側空間無視 / 高次脳機能障害 / 視覚弁別 / 視覚性注意 / 神経伝達物質 / 動機づけ |
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| Research Abstract |
Motivation and attention play an important role in flexible and efficient decision making. We investigated the effects of dopaminergic and acetylcholinergic drugs on the performance of visual discrimination. In control subjects, l-dopa and donepezil both improved performance of visual discrimination. In right brain damage patients, left hemispatial neglect was ameliorated by both l-dopa and donepezil. The results suggest that both dopaminergic and acetylcholinergic systems are involved in visual processing.
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Report
(4 results)
Research Products
(17 results)
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[Journal Article] Some evidence supporting the safety of quadripulse stimulation (QPS).2011
Author(s)
Nakatani-Enomoto S, Hanajima R, Hamada M, Mochizuki H, Kobayashi S, Enomoto H, Sugiura Y, Matsumoto H, Furubayashi T, Terao Y, Sato F, Ugawa Y
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Journal Title
Brain Stimul
Volume: 4
Pages: 303-305
Related Report
Peer Reviewed
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