| Project/Area Number |
23500409
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neuroscience in general
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| Research Institution | National Center of Neurology and Psychiatry |
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Principal Investigator |
SUZUKI Wataru 独立行政法人国立精神・神経医療研究センター, 神経研究所・微細構造研究部, 室長 (80332336)
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| Co-Investigator(Renkei-kenkyūsha) |
ICHINOHE Noritaka 独立行政法人国立精神・神経医療研究センター, 神経研究所・微細構造研究部, 部長 (00250598)
BANNO Taku 独立行政法人国立精神・神経医療研究センター, 神経研究所・微細構造研究部, 研究員 (70598440)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 運動前野 / リーチング・グラスピング / 生体内神経結合イメージング / マーモセット / ミラーニューロン / 上側頭溝 / 前運動野 / 生体内神経結合イメージン グ |
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| Research Abstract |
In this study, we investigate whether mirror neurons exist in common marmosets (Callithrix jacchus). First we discovered cells responsive to other's grasping action from a posterior part of the superior temporal sulcus, then injected retrograde fluorescent tracer (CTB- Alexa555) into the region. One week later, by using a fluorescence stereomicroscope, we were able to identify the regions containing the labeled cells in the ventral premotor cortex. Finally, we implanted linear array multi-contact electrodes into both labeled regions in the ventral premotor cortex and tracer injection site in the superior temporal sulcus, and recorded multi-units under awake condition. We found a significant number of multi-unit in the ventral premotor cortex were mirror neurons which showed significant responses both when performing a grasping action and when observing the experimenter performing various grasping actions.
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