| Project/Area Number |
23500419
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Kawasaki Medical School |
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Principal Investigator |
KIYOKAGE EMI 川崎医科大学, 医学部, 講師 (30543392)
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| Co-Investigator(Renkei-kenkyūsha) |
TOIDA Kazunori 川崎医科大学, 解剖学, 教授 (40253405)
KANEKO Takeshi 京都大学, 高次脳形態学, 教授 (90177519)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | ＴＨ / 嗅球 / 糸球体 / 介在ニューロン / シナプス / ３次元再構築 / 電子顕微鏡 / THニューロン / シナプス解析 / 嗅覚神経回路 |
|---|
| Research Abstract |
Glomeruli are the initial site of synaptic integration in the olfactory pathway. Each glomerulus acts on the modulation of odor information inputs as a functional unit. We focus on tyrosine hydroxylase (TH) neurons that constitute glomeruli, and performed quantitative analysis of synapses TH neurons formed using correlative observation of immunoreactivity in confocal laser-scanning microscopy and transmission electron microscopy. Analysis of special distribution of synapses on TH neuron improves to understand the neural circuit for regulation of odor information.
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