| Project/Area Number |
23500485
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Fusional brain recording science
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| Research Institution | National Center of Neurology and Psychiatry |
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Principal Investigator |
HANAKAWA TAKASHI 独立行政法人国立精神・神経医療研究センター, 脳病態統合イメｰジングセンタｰ先進脳画像研究部, 部長 (30359830)
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| Co-Investigator(Renkei-kenkyūsha) |
UGAWA Yoshikazu 福島県立医科大学, 医学部, 教授 (50168671)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 脳刺激 / 神経可塑性 / 運動 / 神経機能画像 / 認知 / リハビリテーション / 非侵襲脳機能計測 / 可塑性 / 脳機能イメージング / 非侵襲脳刺激 / 脳機能操作 / 多次元イメージング / 神経科学 / 臨床神経生理学 |
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| Research Abstract |
Non-invasive magnetic and electric brain stimulation allows us to modulate neural functions for a certain period of time. It thus seems possible to use brain stimulation technique for therapeutic purpose in neuro-psychiatric disorders. However, it remains unclear how brain stimulation changes neural activity, thereby modifying behaviors. Here we addressed this question by combining brain stimulation with functional magnetic resonance imaging. We found that brain stimulation modifies functions of neural network connected with the stimulated site for a certain period of time. We also found that large inter-subject variability for the effects of brain stimulation, and this was in part accounted for by inter-subject variability of how an individual uses his/her brain. We will further advance these lines of research toward establishment of brain stimulation as a therapeutic option for neuro-psychiatric disorders.
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