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Study on wavelength dependency of the effectiveness of UV-A sterilization and its mechanism

Research Project

Project/Area Number 23500519
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionThe University of Tokushima

Principal Investigator

AKUTAGAWA Masatake  徳島大学, ソシオテクノサイエンス研究部, 講師 (90294727)

Co-Investigator(Kenkyū-buntansha) TAKAHASHI Akira  徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授 (90304047)
Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords近紫外線 / 遺伝子発現 / 腸炎ビブリオ / 殺菌 / 遺伝子発現解析 / 波長依存性 / 遺伝子解析
Outline of Final Research Achievements

The purpose of this study is to investigate fundamental knowledge of response mechanisms for near-ultraviolet (UV-A) exposure from the view of gene expression levels. Vibrio parahaemolyticus was examined to compare the gene expression levels for UV-A of five different wavelengths irradiated from a xenon lamp. As result of experiments, (1) difference of the gene expression level was observed in several parts of the flagellar complex. Particular difference of the level was observed for wavelength of 365 nm. (2) difference of the level was observed in several parts which are related to the histidine metabolism. Particular difference for wavelength of 340 nm. (1) suggests that exposure of UV-A with wavelength of 365 nm may affects on migration of the vibrio parahaemolyticus and the number of flagellum. (2) suggests exposure of UV-A with wavelength of 340 nm may affects on production of histidine.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (9 results)

All 2014 2013 2012 2011

All Presentation (9 results)

  • [Presentation] UV及び可視光照射に対する腸炎ビブリオの遺伝子発現解析2014

    • Author(s)
      星山 哲平, 芥川 正武, 榎本 崇宏, 中橋 睦美, 林田 麻里王, 髙橋 章, 馬渡 一諭, 池原 敏孝, 小中 信典, 木内 陽介
    • Organizer
      電気関係学会四国支部連合大会
    • Place of Presentation
      徳島大学(徳島県徳島市)
    • Year and Date
      2014-09-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] 異なる波長の光照射に対する腸炎ビブリオの遺伝子発現解析2014

    • Author(s)
      星山 哲平, 芥川 正武, 榎本 崇宏, 中橋 睦美, 林田 麻里王, 髙橋 章, 馬渡 一諭, 池原 敏孝, 小中 信典, 木内 陽介
    • Organizer
      MEとバイオサイバネティックス研究会
    • Place of Presentation
      岡山大学(岡山県岡山市)
    • Year and Date
      2014-07-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] Gene expression analysis of Vibrio parahaemolyticus for UV irradiation2013

    • Author(s)
      Teppei Hoshiyama, Masatake Akutagawa, Mutsumi Aihara, Mario Hayashida, Akira Takahashi, Takahiro Emoto, Shinsuke Konaka and Yohsuke Kinouchi
    • Organizer
      BioEM2013
    • Place of Presentation
      Conference Center of Thessaloniki Concert Hall (ギリシャ)
    • Related Report
      2013 Research-status Report
  • [Presentation] Represent UV-A sterilization by model equation2013

    • Author(s)
      Masachika Ishizaki and Masatake Akutagawa
    • Organizer
      BioEM2013
    • Place of Presentation
      Conference Center of Thessaloniki Concert Hall (ギリシャ)
    • Related Report
      2013 Research-status Report
  • [Presentation] UV照射に対する腸炎ビブリオの遺伝子発現解析2013

    • Author(s)
      星山 哲平, 芥川 正武, 榎本 崇宏, 小中 信典, 木内 陽介, 粟飯原 睦美, 林田 麻里王, 髙橋 章
    • Organizer
      平成25年度電気関係学会四国支部連合大会
    • Place of Presentation
      徳島大学工学部(徳島県)
    • Related Report
      2013 Research-status Report
  • [Presentation] UV-A殺菌推移を表すモデル化に関する研究2013

    • Author(s)
      石崎 仁愛, 芥川 正武, 髙橋 章, 木内 陽介, 榎本 崇宏, 池原 敏孝, 小中 信典
    • Organizer
      平成25年度電気関係学会四国支部連合大会
    • Place of Presentation
      徳島大学工学部(徳島県)
    • Related Report
      2013 Research-status Report
  • [Presentation] Improvement of a pipe type UVA-LED sterilizer using a condenser lens2012

    • Author(s)
      Masachika Ishizaki, et al
    • Organizer
      34th Annual Conference of the bioelectromagnetics society (34 BEMS)
    • Place of Presentation
      Brisbane Convention & Exhibition Centre(オーストラリア)
    • Related Report
      2012 Research-status Report
  • [Presentation] UVAによる殺菌のモデル化に関する研究2012

    • Author(s)
      石崎 仁愛 他
    • Organizer
      電気関係学会四国支部連合大会
    • Place of Presentation
      四国電力株式会社総合研修所(香川県)
    • Related Report
      2012 Research-status Report
  • [Presentation] UVA-LEDを用いたパイプ型殺菌装置におけるレンズの効果2011

    • Author(s)
      真鍋 佑輔
    • Organizer
      平成23年度 電気関係学会四国支部連合大会
    • Place of Presentation
      阿南工業高等専門学校(徳島県)
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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