| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
|
|---|
| Research Abstract |
Recently, photoacoustic imaging has attracted attention to visualize small vessels in deep tissues. The objective of this study is to improve the spatial resolution, penetration depth, and image contrast in photoacoustic imaging with improved light illumination. Based on our observations in this study (the one-photon photoacoustic signal was constant in spite of the pulse duration, though the two-photon photoacoustic signal was increased with decrease in pulse duration), we proposed a subtraction method employing two images obtained by ultrashort pulses with two different pulse durations to extract the two-photon photoacoustic signals. The subtraction method enables us to visualize cross-sectional images with high spatial resolution and high contrast.
|
