Polarization analysis of age-related changes of the crystalline lens with high sensitivity OCT
Project/Area Number |
23500529
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Biomedical engineering/Biological material science
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Research Institution | Kitasato University |
Principal Investigator |
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Project Period (FY) |
2011 – 2013
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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Keywords | OCT / 医用生体工学 / 光干渉断層計測 / 偏光感受型OCT / 生体計測 / 前眼部OCT / 生体医工学 / 偏光計測 / 偏光 |
Research Abstract |
We developed a high-speed, high-sensitivity, swept-source optical coherence tomography (SS-OCT) system with a depth range of 12 mm and a fast A-scan rate of 20,000 times per second, providing high-quality imaging of the whole anterior segment. Using this SS-OCT system, we measured curvature of the anterior and posterior surfaces of the lens, thickness of the lens, and anterior chamber depth in response to far (0.4 D) and near (10 D) accommodative stimulus targets. The radius of curvature of the anterior and posterior surface of the human lens became smaller with accommodation, and changes in the anterior surface were larger than the posterior. Morphometric changes of the lens with accommodation reduced with aging, except for posterior surface curvature.
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Report
(4 results)
Research Products
(11 results)
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[Journal Article] Image diversity , shape modification with accommodation , dynamical change with accommodation, and age dependence of the ciliary body imaged by optical coherence tomography2012
Author(s)
Kimiya Shimizu, Nobuyuki Satoh, Akihito Igarashi, Motoi Nakanishi, Atsushi Goto, Donghak Choi, Reiko Yoshimura, Hideaki Hiro-Oka , Hiroyuki Furukawa , Kohji Ohbayashi
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Journal Title
Proc. SPIE , Ophthalmic Technologies XXII
Volume: 8209
Pages: 8209091-8209099
DOI
Related Report
Peer Reviewed
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[Journal Article] Discretely swept optical coherence tomography system using super-structure grating distributed Bragg reflector lasers at 1561-1639nm2012
Author(s)
Donghak Choi, Reiko Yoshimura, Hideaki Hiro-Oka, Hiroyuki Furukawa, Atsushi Goto, Nobuyuki Satoh, Akihito Igarashi, Motoi Nakanishi, Kimiya Shimizu, Kohji Ohbayashi
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Journal Title
Proc. SPIE, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI
Volume: 8213
DOI
Related Report
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[Presentation] Image diversity , shape modification with accommodation , dynamical change with accommodation, and age dependence of the ciliary body imaged by optical coherence tomography2012
Author(s)
Kimiya Shimizu, Nobuyuki Satoh, Akihito Igarashi, Motoi Nakanishi, Atsushi Goto, Donghak Choi, Reiko Yoshimura, Hideaki Hiro-Oka , Hiroyuki Furukawa , Kohji Ohbayashi
Organizer
Photonics West 2012
Place of Presentation
San Francisco, California, USA
Year and Date
2012-01-21
Related Report
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[Presentation] Image diversity, shape modification with accommodation, dynamical change with accommodation, and age dependence of the ciliary body imaged by optical coherence tomography2012
Author(s)
Kimiya Shimizu, Nobuyuki Satou, Akihito Igarashi, Motoi Nakanishi, Atsushi Goto, Donghak Choi, Reiko Yoshimura, Hideaki Hiro-Oka, Hiroyuki Furukawa, Kohji Ohbayashi
Organizer
Photonics West 2012
Place of Presentation
San Francisco, California, USA
Related Report
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[Presentation] Discretely swept optical coherence tomography system using super-structure grating distributed Bragg reflector lasers at 1561-1639nm2012
Author(s)
Donghak Choi, Reiko Yoshimura, Hideaki Hiro-Oka, Hiroyuki Furukawa, Atsushi Goto, Nobuyuki Satoh, Akihito Igarashi, Motoi Nakanishi, Kimiya Shimizu, Kohji Ohbayashi
Organizer
Photonics West 2012
Place of Presentation
San Francisco, California, USA
Related Report
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[Presentation] Imaging the Whole Anterior Segment of Human Accommodation by Swept-Source Optical Coherence Tomography2011
Author(s)
Hiroyuki Furukawa, Hideaki Hiro-Oka, Nobuyuki Satoh, Reiko Yoshimura, Donghak Choi, Motoi Nakanishi, Akihito Igarashi, Kohji Ohbayashi, Kimiya Shimizu
Organizer
Association for Research in Vision and Ophthalmology/ISIE Imaging Conference
Place of Presentation
Fort Lauderdale, Florida, USA
Related Report
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