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Photo-stimulating effect of low reactive level laser on overactive bladder and interstitial cystitis

Research Project

Project/Area Number 23500551
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical systems
Research InstitutionDokkyo Medical University (2012-2014)
Chiba University (2011)

Principal Investigator

UCHIYAMA Tomoyuki  獨協医科大学, 医学部, 准教授 (70345015)

Co-Investigator(Kenkyū-buntansha) YAMAMOTO Tatsuya  千葉大学, 医学研究院, 助教 (50375755)
YANAGISAWA Mitsuru  千葉大学, 医学部附属病院, 助教 (70436393)
山口 千晴 (柴田 千晴)  千葉大学, 医学部附属病院, その他 (40533344)
Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords過活動膀胱 / 神経因性膀胱 / 間質性膀胱炎 / 半導体レーザー / 尿意切迫感 / 膀胱痛 / 低反応レベルレーザー / 治療
Outline of Final Research Achievements

New therapy is strongly needed both for overactive bladder which increase in an aging society and refractory interstitial cystitis. We clinically evaluated about photo-stimulating effect of low reactive level laser on overactive bladder and interstitial cystitis in human.
We observed that maximum bladder capacity incresed and detrusor overactive is reduced after a single photo-stimulation to bilateral sacral foramens (S2-4).
We also observed that maximum bladder capacity incresed and detrusor overactive is reduced and that the carry-over effect is presented after twelve times (twice per week) photo-stimulation to bilateral sacral foramens (S2-4). However, further study is needed becaause a group in this study is very small.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (5 results)

All 2015 2014 2013 2012

All Presentation (5 results) (of which Invited: 1 results)

  • [Presentation] Photo-stimulating effect of low reactive level laser on lower urinary tract dysfunction in Parkinson disease model2015

    • Author(s)
      Uchiyama T, Yamamoto T, Watanabe Y, Kadowaki T, Hashimoto T, Shingo T, Kaga K, Shibata-Yamaguchi C, Yamanishi T, Sakakibara R, Kuwabara S, Hirata K
    • Organizer
      XXII World Congress of Neurology
    • Place of Presentation
      Santiago, Chile
    • Year and Date
      2015-10-31 – 2015-11-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Photo-stimulation using low reactive level laser can improve abnormal micturition reflex in spinal cord injury model2014

    • Author(s)
      Uchiyama T, Yamamoto T, Shibata-Yamaguchi C, Kaga K, Fuse M, Watanabe Y, Awa Y, Kamai T, Yamanishi T, Sakakibara R, Kuwabara S, Hirata K
    • Organizer
      44th International Continence Society
    • Place of Presentation
      Rio de Janeiro, Brazil
    • Year and Date
      2014-10-20 – 2014-10-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] Subthalamic deep brain stimulation can improve gastric emptying in Parkinson’s disease.2013

    • Author(s)
      Uchiyama T, Arai E, Arai M, Higuchi Y, Yamamoto T, Yamanaka Y, Aoyagi K, Shina A, Shibata-Yamaguchi C, Fuse M, Tateno H, Kamai T, Yamanishi T, Yokosuka O, Saeki N, Sakakibara R, Hirata K, Kuwabara S
    • Organizer
      XXI World Congress of Neurology
    • Place of Presentation
      Wien
    • Related Report
      2013 Research-status Report
  • [Presentation] 自律神経不全の治療最前線 今、目の前の患者さんにできること 排尿障害の治療 経験を踏まえて.2013

    • Author(s)
      内山智之, 柴田千晴, 山本達也, 榊原 隆次, 舘野 広美, 布施 美樹, 山西 友典, 桑原 聡, 平田 幸一
    • Organizer
      第66回日本自律神経学会
    • Place of Presentation
      名古屋
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Mechanisms of urinary dysfunction in Parkinson’s disease; participation in basal ganglia circuitry and sensory and autonomic/emotional nervous systems2012

    • Author(s)
      Uchiyama T, Yamanishi T, Sakakibara R, Yoshiyama M, Liu Z, Yamamoto T, Yamaguchi C, Yanagisawa M, Higuchi Y, Kuwabara S
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin
    • Related Report
      2012 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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