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Development of segmentation and visualization method for brain in DT-MRI

Research Project

Project/Area Number 23500561
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical systems
Research InstitutionKyushu University

Principal Investigator

KUMAZAWA Seiji  九州大学, 医学(系)研究科(研究院), 講師 (50363354)

Co-Investigator(Kenkyū-buntansha) YOSHIURA Takashi  鹿児島大学, 大学院・医歯学総合研究科, 教授 (40322747)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
KeywordsMRI / 拡散テンソル / 拡散MRI / ADC / 白質 / 皮質 / 灰白質 / 白質線維束 / MRI / 脳機能
Research Abstract

Our purpose was to develop a new brain tissue segmentation method based on diffusion tensor (DT) MRI without the need for any registration, taking the partial volume effect into account, and to improve the estimation of the white matter fiber tract pathways in the fiber crossing area. Our method was based on the multiple-tensor model and a maximum a posteriori probability principle using DT parameters derived from DT-MRI dataset. The results of the digital phantom experiment and human DT-MRI data demonstrate that our method was able to perform a reasonable estimation and segmentation for brain tissue on DT-MRI data compared with the previous method.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (35 results)

All 2014 2013 2012 2011 Other

All Journal Article (6 results) (of which Peer Reviewed: 5 results) Presentation (29 results)

  • [Journal Article] Improvement of Partial Volume Segmentation for Brain Tissue on Diffusion Tensor Images using Multiple-tensor Estimation2013

    • Author(s)
      Kumazawa S, Yoshiura T, Honda H, Toyofuku F
    • Journal Title

      Journal of Digital Imaging

      Volume: Vol.26, No.6 Pages: 1131-1140

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Improvement of Partial Volume Segmentation for Brain Tissue on Diffusion Tensor Images using Multiple-tensor Estimation2013

    • Author(s)
      Kumazawa Seiji, Yoshiura Takashi, Honda Hiroshi, Toyofuku Fukai
    • Journal Title

      Journal of Digital Imaging

      Volume: 26 Issue: 6 Pages: 1131-1140

    • DOI

      10.1007/s10278-013-9601-z

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Alzheimer's disease : Diagnosis by different methods of voxel-based morphometry2012

    • Author(s)
      Dashjamts T, Yoshiura T, Hiwatashi A, et al
    • Journal Title

      Fukuoka Acta Medica

      Volume: Vol.103, No.3 Pages: 59-68

    • NAID

      40019326251

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 拡散テンソルMRIとその解析・可視化技術2012

    • Author(s)
      熊澤誠志
    • Journal Title

      医学物理

      Volume: 32巻2号 Pages: 67-73

    • NAID

      130003397831

    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Journal Article] Usefulness of high-resolution STIR at 3T in posterior fossa: visualization of the lower cranial nerves and vessels2012

    • Author(s)
      Hiwatashi A, Yoshiura T, Yamashita K, Kamano H, Dashjamts T, Honda H
    • Journal Title

      AJR Am J Roentogenol

      Volume: 199 Issue: 3 Pages: 644-648

    • DOI

      10.2214/ajr.11.6566

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Detection of middle ear cholesteatoma by diffusion-weighted MR imaging: multi-shot echo-planar imaging compared to single-shot echo-planar imaging2011

    • Author(s)
      Yamashita K, Yoshiura T, Hiwatashi A, et al
    • Journal Title

      AJNR Am J Neuroradiol

      Volume: Vol.32, No.10 Pages: 1915-1918

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] A validation of the biexponential model in diffusion MRI signal attenuation using diffusion Monte Carlo simulator2014

    • Author(s)
      Nishigake D, Kumazawa S, Yabuuchi H, Toyofuku F
    • Organizer
      European congress of radiology
    • Year and Date
      2014-03-07
    • Related Report
      2013 Final Research Report
  • [Presentation] Investigation of influences of the magnetic field inhomogeneity due to the subject positioning on the apparent diffusion coefficient in the cerebral cortex using MRI simulator2013

    • Author(s)
      Ushijima D, Kumazawa S, Yabuuchi H, Ohki M
    • Organizer
      Radiological Society of North America (RSNA)
    • Year and Date
      2013-12-03
    • Related Report
      2013 Final Research Report
  • [Presentation] A Novel Image-based Estimation Method for Magnetic Field Inhomogeneity in Brain Echo-planar Image2013

    • Author(s)
      Kumazawa S, Yoshiura T, Honda H, Toyofuku F
    • Organizer
      Radiological Society of North America(RSNA)
    • Year and Date
      2013-12-02
    • Related Report
      2013 Final Research Report
  • [Presentation] An investigation of the influence of image distortion on the measurement of apparent diffusion coefficient (ADC)2013

    • Author(s)
      Ushijima D, Kumazawa S, Yabuuchi H, and Ohki M
    • Organizer
      European congress of radiology
    • Year and Date
      2013-03-07
    • Related Report
      2013 Final Research Report
  • [Presentation] An investigation of the influence of image distortion on the measurement of apparent diffusion coefficient (ADC) values in the cerebral cortex using diffusion MRI simulator2013

    • Author(s)
      Daigo Ushijima, Seiji Kumazawa, Hidetake Yabuuchi, and Masafumi Ohki
    • Organizer
      European congress of radiology
    • Place of Presentation
      オーストリア ウィーン
    • Related Report
      2012 Research-status Report
  • [Presentation] Development of a novel a partial volume brain tissue segmentation method based on diffusion tensor MR imaging data using multi-tensor model2012

    • Author(s)
      Kumazawa S, Yoshiura T, Honda H, Toyofuku F
    • Organizer
      European congress of radiology
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2012-03-01
    • Related Report
      2013 Final Research Report
  • [Presentation] 混合ガウス分布モデルを用いたMR画像における局所的な画像信号強度不均一に対する補正法の開発2012

    • Author(s)
      甲斐征八,熊澤誠志,藪内英剛,豊福不可依
    • Organizer
      第68回日本放射線技術学会総会学術大会
    • Place of Presentation
      横浜市
    • Related Report
      2012 Research-status Report
  • [Presentation] Echo planar imaging(EPI)画像シミュレータを用いた幾何学的歪みと撮像パラメータの検討2012

    • Author(s)
      牛島大悟, 熊澤誠志
    • Organizer
      第68回日本放射線技術学会総会学術大会
    • Place of Presentation
      横浜市
    • Related Report
      2012 Research-status Report
  • [Presentation] 混合ガウスモデルを用いた高磁場MR画像における局所的な信号強度不均一に対する補正法の開発2012

    • Author(s)
      甲斐征八、熊澤誠志、藪内英剛、豊福不可依
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      京都市
    • Related Report
      2012 Research-status Report
  • [Presentation] シミュレータを用いたEPI画像における幾何学的歪みとSNRの最適化:バンド幅による検討2012

    • Author(s)
      牛島大悟、熊澤誠志、藪内英剛、大喜雅文
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      京都市
    • Related Report
      2012 Research-status Report
  • [Presentation] 頭部EPI画像におけるフィールドマップの画像ベース推定手法2012

    • Author(s)
      熊澤誠志,吉浦敬,本田浩,豊福不可依
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      京都市
    • Related Report
      2012 Research-status Report
  • [Presentation] 拡散テンソルMRIとその解析・可視化技術2012

    • Author(s)
      熊澤誠志
    • Organizer
      第1回JBMP放射線治療品質管理・医学物理講習会
    • Place of Presentation
      つくば市
    • Related Report
      2012 Research-status Report
  • [Presentation] 高分解能拡散テンソル画像による皮質内有髄線維の評価2012

    • Author(s)
      吉浦敬、樋渡昭雄、山下孝二、菊地一史、本田浩、栂尾理、鈴木諭、岡本剛
    • Organizer
      第71回日本医学放射線学会学術集会
    • Place of Presentation
      横浜市
    • Related Report
      2012 Research-status Report
  • [Presentation] In-vivo detection of intracortical myelinated fibers in human hippocampal formation: submillimeter resolution diffusion tensor imaging compared with histological findings2012

    • Author(s)
      Yoshiura T, Hiwatashi A, Suzuki OS, Okamoto T, Togao O, Yamashita K, Kikuchi K, Honda H
    • Organizer
      ISMRM 20th Annual Meeting and Exhibition
    • Place of Presentation
      Melbourne, Australia
    • Related Report
      2012 Research-status Report
  • [Presentation] Development of a novel a partial volume brain tissue segmentation method based on diffusion tensor MR imaging data using multi-tensor model2012

    • Author(s)
      Kumazawa S, Yoshiura T, Honda H, Toyofuku F
    • Organizer
      European congress of radiology
    • Place of Presentation
      Viena, Austria
    • Related Report
      2011 Research-status Report
  • [Presentation] Correction of the local intensity nonuniformity artifact in high field MR2012

    • Author(s)
      Kai S, Kumazawa S, Yabuuchi H, Toyofuku F
    • Organizer
      European congress of radiology
    • Place of Presentation
      Viena, Austria
    • Related Report
      2011 Research-status Report
  • [Presentation] A correction method for the local intensity nonuniformity in MR images based on the Gaussian profile model2011

    • Author(s)
      Kai S, Kumazawa S, Yabuuchi H, and Toyofuku F
    • Organizer
      6th Japan-Korea Joint Meeting on Medical Physics 11th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2011-09-23
    • Related Report
      2013 Final Research Report
  • [Presentation] Brain tissue segmentation for diffusion tensor imaging (DTI) data using multi-tensor estimation2011

    • Author(s)
      Kumazawa S, Yoshiura T, Honda H, Toyofuku F
    • Organizer
      International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2011-05-10
    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Presentation] A correction method for the local intensity nonuniformity in MR images based on the Gaussian profile model2011

    • Author(s)
      Kai S, Kumazawa S, Yabuuchi H, Toyofuku F
    • Organizer
      6th Japan-Korea Joint Meeting on Medical Physics 11th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Fukuoka
    • Related Report
      2011 Research-status Report
  • [Presentation] Echo-planar imaging (EPI)画像シミュレータを用いた磁化率の違いによる幾何学的歪みの検討2011

    • Author(s)
      牛島大悟 熊澤誠志
    • Organizer
      第6回九州医療技術学術大会
    • Place of Presentation
      鹿児島
    • Related Report
      2011 Research-status Report
  • [Presentation] EPI画像におけるfield mapping法および非剛体レジストレーション法を用いた歪み補正効果の検討2011

    • Author(s)
      閏木崇彦 甲斐征八 熊澤誠志
    • Organizer
      第6回九州医療技術学術大会
    • Place of Presentation
      鹿児島
    • Related Report
      2011 Research-status Report
  • [Presentation] MR画像における局所的な信号強度不均一に対するガウス関数モデルを用いた補正法の開発2011

    • Author(s)
      甲斐征八 熊澤誠志 藪内英剛 豊福不可依
    • Organizer
      第6回九州医療技術学術大会
    • Place of Presentation
      鹿児島
    • Related Report
      2011 Research-status Report
  • [Presentation] High-resolution diffusion-tensor imaging: detection of intracortical myelinated fibers in the medial temporal lobe2011

    • Author(s)
      Yoshiura T, Hiwatashi A, Yamashita K, Suzuki S, Kamano H, Honda H
    • Organizer
      97th Scientific Assembly and Annual Meeting of Radiological Society of North America
    • Place of Presentation
      Chicago, USA
    • Related Report
      2011 Research-status Report
  • [Presentation] 拡散テンソル画像による皮質内有髄線維の評価2011

    • Author(s)
      吉浦敬、樋渡昭雄、栂尾理、山下孝二、菊地一史、本田浩
    • Organizer
      第39回日本磁気共鳴医学会大会
    • Place of Presentation
      北九州市
    • Related Report
      2011 Research-status Report
  • [Presentation] 共役勾配法を用いた頭部EPI画像における画像ベースのフィールドマップ推定

    • Author(s)
      熊澤 誠志, 吉浦 敬, 本田 浩, 豊福 不可依
    • Organizer
      第41回日本磁気共鳴医学会大会
    • Place of Presentation
      アスティとくしま
    • Related Report
      2013 Annual Research Report
  • [Presentation] DWIにおける大脳皮質のADC値への磁場不均一の影響:MRIシミュレータを用いた検討

    • Author(s)
      牛島大悟, 熊澤 誠志, 藪内 英剛, 大喜 雅文
    • Organizer
      第41回日本磁気共鳴医学会大会
    • Place of Presentation
      アスティとくしま
    • Related Report
      2013 Annual Research Report
  • [Presentation] 頭部ポジショニングの違いが大脳皮質のADC値に与える影響:MRIシミュレータを用いた検討

    • Author(s)
      牛島大悟, 熊澤 誠志, 藪内 英剛, 大喜 雅文
    • Organizer
      第41回日本放射線技術学会秋季学術大会
    • Place of Presentation
      アクロス福岡
    • Related Report
      2013 Annual Research Report
  • [Presentation] Development of a Novel Partial Volume Brain Tissue Segmentation Method Based on Diffusion Tensor MR Imaging Data Using Multi-tensor Model

    • Author(s)
      Kumazawa Seiji, Yoshiura Takashi, Honda Hiroshi, Toyofuku Fukai
    • Organizer
      Radiological Society of North America(RSNA)
    • Place of Presentation
      Chicago, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Investigation of influences of the magnetic field inhomogeneity due to the subject positioning on the apparent diffusion coefficient in the cerebral cortex using MRI simulator

    • Author(s)
      Ushijima Daigo, Kumazawa Seiji, Hidetake Yabuuchi, Masafumi Ohki
    • Organizer
      Radiological Society of North America(RSNA)
    • Place of Presentation
      Chicago, USA
    • Related Report
      2013 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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