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Tissue characterization of unstable coronary plaque using IB signal and coronary CT

Research Project

Project/Area Number 23500572
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical systems
Research InstitutionKawasaki Medical School

Principal Investigator

KAWAMOTO Takahiro  川崎医科大学, 医学部, 講師 (30368667)

Co-Investigator(Kenkyū-buntansha) NEISHI Yoji  川崎医科大学, 医学部, 講師 (80319946)
OKURA Hiroyuki  川崎医科大学, 医学部, 准教授 (30425136)
YOSHIDA Kiyoshi  川崎医科大学, 医学部, 教授 (60322583)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Keywords冠動脈CT / 虚血性心疾患
Research Abstract

We analyzed 20 cases with acute coronary syndrome using intravascular ultrasound and IB signal analysis. The characteristics of unstable coronary plaque were identified by this analysis. Then 25 cases with angina pectoris who underwent both of coronary CT and coronary angiography were included next study. We analyzed 59 lesions showing more than 50% diameter stenosis on coronary CT and classified into 4 types of lesions; calcified, non-calcified, mixed, and non-plaque. Overall positive predictive value was 64% and we revealed that it was not same at each 4 types of lesion character; 33.3% of calcified, 91.7% of non-calcified, 50% of mixed, and 56.2% of non-plaque lesion.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (8 results)

All 2013 2012 2011 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (4 results)

  • [Journal Article] A unique feature of thin flat thrombus visualised by optical coherence tomography2013

    • Author(s)
      Kume T, Okura H, Fukuhara K, Koyama T, Nezuo S, Neishi Y, Hayashida A, Kawamoto T, Yoshida K
    • Journal Title

      EuroIntervention

      Volume: 9(8) Pages: 1008-1008

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Visualization of coronary plaque vasa vasorum by intravascular ultrasound2013

    • Author(s)
      Kume T, Okura H, Fukuhara K, Koyama T, Yamada R, Neishi Y, Hayashida A, Kawamoto T, Yoshida K
    • Journal Title

      JACC Cardiovasc Interv

      Volume: 6(9) Pages: 985-985

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Natural history of stent edge dissection, tissue protrusion and incomplete stent apposition detectable only on optical coherence tomography after stent implantation - preliminary observation -2012

    • Author(s)
      Kume T, Okura H, Miyamoto Y, Yamada R, Saito K, Tamada T, Koyama T, Neishi Y, Hayashida A, Kawamoto T, Yoshida K
    • Journal Title

      Circ J

      Volume: 76(3) Pages: 698-703

    • NAID

      10030130249

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Plaque characteristics of thin-cap fibroatheroma evaluated by OCT and IVUS2011

    • Author(s)
      Miyamoto Y, Okura H, Kume T, Kawamoto T, Neishi Y, Hayashida A, Yamada R, Imai K, Saito K, Yoshida K
    • Journal Title

      JACC Cardiovasc Imaging

      Volume: 4(6) Pages: 638-46

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] 心不全患者におけるトルバプタン新規投与時の利尿効果と併用薬の関係2013

    • Author(s)
      川元隆弘, 大倉宏之, 根石陽二, 林田晃寛, 久米輝善, 尾長谷喜久子, 今井孝一郎, 鼠尾晋太郎, 玉田智子, 古山輝將, 吉田清
    • Organizer
      第61回日本心臓病学会学術集会
    • Place of Presentation
      ホテル日航熊本(熊本)
    • Year and Date
      2013-09-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 心臓CTでの冠動脈狭窄診断に及ぼす冠動脈プラーク性状の影響2013

    • Author(s)
      比嘉冨貴, 大倉宏之, 根石陽二, 林田晃寛, 久米輝善, 尾長谷喜久子, 今井孝一郎, 鼠尾晋太郎, 玉田智子, 古山輝將, 川元隆弘, 吉田清
    • Organizer
      第23回日本心血管画像動態学
    • Place of Presentation
      東京ステーションコンファレンス(東京)
    • Year and Date
      2013-01-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 心臓CTでの冠動脈狭窄診断に及ぼす冠動脈プラーク性状の影響2013

    • Author(s)
      比嘉 富貴
    • Organizer
      日本心血管画像動態学会
    • Place of Presentation
      東京ステーションコンファレンス(東京)
    • Related Report
      2012 Research-status Report
  • [Presentation] 心不全患者におけるトルバプタン新規投与時の利尿効果と併用薬の関係

    • Author(s)
      川元 隆弘
    • Organizer
      日本心臓病学会
    • Place of Presentation
      ホテル日航熊本(熊本)
    • Related Report
      2013 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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