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Influence of nerve system to the histopathological changes of joint contracture. A study using experimental spinal cord injury model in rat.

Research Project

Project/Area Number 23500581
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKanazawa University

Principal Investigator

HOSO Masahiro  金沢大学, 保健学系, 教授 (20219182)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords拘縮 / 末梢神経切断 / 創外固定 / 関越構成体 / 関節構成体 / 病理 / 関節拘縮 / 脊髄損傷 / 動物実験
Research Abstract

The histopathological changes of the joint components and the periphery of sciatic nerve after experimental spinal cord injury in rat were disclosed. The changes of the joint components were slight and stayed, compare to the changes during experimental joint contracture using Kirschner wires in rat. On the contrast, the changes of the periphery of sciatic nerve were similar to the changes during experimental joint contracture using Kirschner wires in rat. The results suggest some influence of somatic nerve and/or autonomic nerve function, to the mechanism of joint contracture state.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (23 results)

All 2013 2012 2011 Other

All Journal Article (7 results) (of which Peer Reviewed: 5 results) Presentation (16 results) (of which Invited: 2 results)

  • [Journal Article] Histopathological Changes in Joint Components in a Rat Knee Joint Contracture Model Following Mobilization2013

    • Author(s)
      Watanabe M, Hoso M, Kojima S, Hibino I, Matsuzaki T
    • Journal Title

      J. Phys. Ther. Sci

      Volume: 24 Pages: 1199-1203

    • NAID

      10031148269

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Histopathological Changes in Knee Joint Components after Spinal Cord Injury in Rats2012

    • Author(s)
      Kitade I, Hoso M, Matsuzaki T, Inaoka PT, Kamijo A, Araki Y, Takahashi Il
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 24 Issue: 1 Pages: 31-35

    • DOI

      10.1589/jpts.24.31

    • NAID

      130004431740

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2013 Final Research Report
  • [Journal Article] Histopathological Changes in Surrounding Tissue of the Sciatic Nerve after Spinal Cord Injury in Rats2012

    • Author(s)
      Kitade I, Hoso M, Matsuzaki T, Yoshida S, Kamijo A, Araki Y, Takahashi Il
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 24 Issue: 9 Pages: 817-820

    • DOI

      10.1589/jpts.24.817

    • NAID

      130004431878

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2013 Final Research Report
  • [Journal Article] ラット膝関節拘縮モデルにおける膝蓋下脂肪体の病理学的変化2012

    • Author(s)
      松崎太郎、小島聖、渡邊晶規、吉田信也、古村千尋、細正博
    • Journal Title

      石川県理学療法学雑誌

      Volume: 12 Pages: 11-14

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Histopathological Cnanges in Knee Joint Component after Spinal Cord Injury in Rats2012

    • Author(s)
      Kitade I, Hoso M, Matsuzaki T, Inaoka PT, Kamijo A, Araki Y, Takahashi Il
    • Journal Title

      J. Phys. Ther. Sci

      Volume: 24 Pages: 31-35

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Histopathological changes in surrounding tissue of the sciatic nerve after spinal cord injury in rats.2012

    • Author(s)
      Kitade I, Hoso M, Matsuzaki T, Yoshida S, Kamijo A, Araki Y, Takahashi Il
    • Journal Title

      J. Phys. Ther. Sci

      Volume: 24 Pages: 817-820

    • NAID

      10031127072

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Histopathological Cnanges in Knee Joint Component after Spinal Cord Injury in Rats2012

    • Author(s)
      Kitade I, Hoso M, Matsuzaki T, et.al
    • Journal Title

      J. Phys. Ther. Sci.

      Volume: 24 Pages: 31-55

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] 動物実験モデルによる関節拘縮の病理組織学2013

    • Author(s)
      細正博
    • Organizer
      第17回福井県理学療法学術大会特別講演
    • Place of Presentation
      サンドーム福井管理会議棟(福井県)
    • Year and Date
      2013-03-09
    • Related Report
      2013 Final Research Report
  • [Presentation] Effect of Exercise during Knee Joint Immobilization on the periphery of the Sciatic Nerve of Rats2013

    • Author(s)
      Yoshida S, Matsuzaki T, Otoji T, Sato E, Terashima M, Togashi K, Hoso M
    • Organizer
      6th WCPT-AWP & 12th ACPT Congress 2013
    • Place of Presentation
      Nan Shan Education & Training Center (Taiwan)
    • Related Report
      2013 Final Research Report
  • [Presentation] Influence of Peripheral Nerve Injury on the Joint Immobilization2013

    • Author(s)
      Matsuzaki T, Ishii K, Tanaka W, Yoshida S, Hoso M
    • Organizer
      6th WCPT-AWP & 12th ACPT Congress 2013
    • Place of Presentation
      Nan Shan Education & Training Center (Taiwan)
    • Related Report
      2013 Final Research Report
  • [Presentation] Influence of Peripheral Nerve Injury on the Joint Immobilization2013

    • Author(s)
      Matsuzaki T, Ishii K, Tanaka W, Yoshida S, Hoso M
    • Organizer
      6th WCPT-AWP & 12th ACPT Congress
    • Place of Presentation
      Nan Shan Education & Training Center (Taichung, Taiwan)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effect of Exercise during Knee Joint Immobilization on the periphery of the Sciatic Nerve of Rats2013

    • Author(s)
      Yoshida S, Matsuzaki T, Otoji T, Sato E, Terashima M, Togashi K, Hoso M
    • Organizer
      6th WCPT-AWP & 12th ACPT Congress
    • Place of Presentation
      Nan Shan Education & Training Center (Taichung, Taiwan)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ラット脊髄損傷における坐骨神経周囲組織の横断的検討2012

    • Author(s)
      北出一平, 細正博, 松崎太郎, 上條明生, 荒木督隆, 高橋郁文
    • Organizer
      第2回基礎理学療法学会
    • Place of Presentation
      兵庫医療大学(兵庫)
    • Year and Date
      2012-05-24
    • Related Report
      2013 Final Research Report
  • [Presentation] ラット脊髄損傷後2週における坐骨神経周囲の病理組織学的検討2012

    • Author(s)
      北出一平, 細正博, 松崎太郎, 上條明生, 荒木督隆, 高橋郁文
    • Organizer
      第47回日本理学療法学術大会
    • Place of Presentation
      神戸ポートピアホテル・神戸国際展示場(兵庫)
    • Related Report
      2013 Final Research Report
  • [Presentation] 関節固定の有無によるラット末梢神経切断モデルの関節構成体の病理組織学的変化2012

    • Author(s)
      田中渉, 松崎太郎, 細正博
    • Organizer
      第47回日本理学療法学術大会
    • Place of Presentation
      神戸ポートピアホテル・神戸国際展示場(兵庫)
    • Related Report
      2013 Final Research Report
  • [Presentation] 関節不動期間中の関節可動域運動の違いが坐骨神経周囲組織に与える影響2012

    • Author(s)
      吉田信也, 松崎太郎, 音地利亮, 佐藤絵美, 寺島未菜, 藤樫和彦, 守山成則, 細正博
    • Organizer
      第47回日本理学療法学術大会
    • Place of Presentation
      神戸ポートピアホテル・神戸国際展示場(兵庫)
    • Related Report
      2013 Final Research Report
  • [Presentation] 関節固定の有無によるラット末梢神経切断モデルの関節構成体の病理組織学的変化2012

    • Author(s)
      田中 渉,松崎 太郎,細 正博
    • Organizer
      第47回日本理学療法学術大会
    • Place of Presentation
      神戸ポートピアホテル、神戸国際展示場(兵庫県)
    • Related Report
      2012 Research-status Report
  • [Presentation] ラット脊髄損傷後2週における坐骨神経周囲の病理組織学的検討2012

    • Author(s)
      北出 一平,細 正博,松崎 太郎,上條 明生,荒木 督隆,高橋 郁文
    • Organizer
      第47回日本理学療法学術大会
    • Place of Presentation
      神戸ポートピアホテル、神戸国際展示場(兵庫県)
    • Related Report
      2012 Research-status Report
  • [Presentation] Histopathological changes in knee joint components after spinal cord injury in rats.2011

    • Author(s)
      Kitade I, Hoso M, Matsuzaki T, Kamijyo A, Araki Y, Takahashi
    • Organizer
      The 6th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Puerto Rico Convention Center (Puerto Rico.)
    • Related Report
      2011 Research-status Report
  • [Presentation] ラット末梢神経損傷モデルにおける関節構成体の病理組織学的変化2011

    • Author(s)
      石井健太郎、細正博、松崎太郎
    • Organizer
      第46回日本理学療法学術大会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎)
    • Related Report
      2011 Research-status Report
  • [Presentation] ラット脊髄損傷における坐骨神経周囲組織の横断的検討

    • Author(s)
      北出一平, 細 正博, 松崎太郎, 上條明生, 荒木督隆, 高橋郁文
    • Organizer
      第2回基礎理学療法学会
    • Place of Presentation
      兵庫医療大学(兵庫県)
    • Related Report
      2012 Research-status Report
  • [Presentation] 関節拘縮の病態─動物実験モデルを用いた検討─

    • Author(s)
      細正博
    • Organizer
      第24回運動器科学会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 動物実験モデルによる関節拘縮の病理組織学

    • Author(s)
      細正博
    • Organizer
      第17回福井県理学療法学術大会
    • Place of Presentation
      サンドーム福井(福井県)
    • Related Report
      2012 Research-status Report
    • Invited

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Published: 2011-08-05   Modified: 2019-07-29  

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