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Comprehensive rehabilitation for patients with peripheral arterial disease

Research Project

Project/Area Number 23500595
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionDokkyo Medical University (2012-2013)
University of the Ryukyus (2011)

Principal Investigator

YASU takanori  獨協医科大学, 医学部, 教授 (40265278)

Co-Investigator(Kenkyū-buntansha) MOMOMURA Shinichi  自治医科大学, 医学部, 教授 (10190985)
OOYA Yuusuke  琉球大学, 医学(系)研究科(研究院), 教授 (30240964)
SASAKI Satoshi  東京大学, 医学(系)研究科(研究院), 教授 (70275121)
ISHIDA Akio  琉球大学, 医学部附属病院, 講師 (10343378)
ISHIKI Tetuya  琉球大学, 医学部附属病院, 助教 (30363667)
KISHIMOTO Yukiaki  琉球大学, 医学部附属病院, 助教 (00567068)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords運動 / 食事 / 末梢動脈疾患
Research Abstract

Lifestyle modification in physical activity and diet may be a key player for primary and secondary prevention of cardiovascular diseases. We conducted a cross-sectional study on physical activity and nutritional status in outpatients with peripheral arterial disease (PAD, n=59), ischemic heart disease (IHD, n=73) and hypertensive and/or chronic kidney disease (CKD, n=222). Physical activity levels in patients with PAD and/or IHD were significantly lower than in patients with hypertension and/or CKD. Age and gender adjusted linear regression analysis indicated that physical activity levels were positively correlated with ABI. Although lipid profiles of patients with PAD and/or IHD were well controlled by medications, the average value of fat intake for daily total calorie intake was high. Life-style modifications such as increase in physical activity and low fat diet are required in Japanese patients with atherosclerotic diseases

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (29 results)

All 2014 2013 2012 2011 Other

All Journal Article (17 results) (of which Peer Reviewed: 8 results) Presentation (12 results)

  • [Journal Article] Improvement of congestive heart failure after adaptive servo-ventilation in a patient with end-stage renal disease on hemodialysis : a case report2014

    • Author(s)
      Aizawa N, Nagahama K, Goya K, Yamazato S, Ikemiyagi H, Oshiro K, Shinzato T, Higashiuesato Y, Ishiki T, Yasu T, Iseki K, Ohya Y
    • Journal Title

      Int Med

      Volume: (in press)

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Contrast echocardiography for the diagnosis of left ventricular thrombus in anterior myocardial infarction2014

    • Author(s)
      Wada H, Yasu T, Sakakura K, Hayakawa Y, Ishida T, Kobayashi N, Kubo N, Ako J, Momomura S
    • Journal Title

      Heart and Vessels

      Volume: (in press)

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinical significance of plasma apolipoprotein F in Japanese healthy and hypertriglyceridemic subjects2013

    • Author(s)
      Kujiraoka T, Nakamoto T, Sugimura H, Iwasaki T, Ishihara M, Hoshi T, Horie Y, Ogawa K, Todoroki M, Nakatani Y, Banba N, Yasu T, Hattori H
    • Journal Title

      J Atheroscler Thromb

      Volume: 20 Pages: 380-390

    • NAID

      130004444670

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dihydropyridine calcium channel blockers inhibit free fatty acid-induced endothelial and rheological dysfunction2013

    • Author(s)
      Yasu T, Kobayashi M, Matsushita A, Yamakawa K, Momomura S, Ueda S
    • Journal Title

      Clin Sci

      Volume: 125 Pages: 247-55

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 虚血性心疾患の疾病管理プログラムとしての外来型心臓リハビリテーションの効果と普及方策に関する研究2013

    • Author(s)
      安隆則
    • Journal Title

      (J-REHAB)分担研究報告書後藤葉一編集厚生労働科学研究費補助金(循環器疾患・糖尿病等生活習慣病対策総合研究事業後藤班)報告書

      Pages: 40-40

    • Related Report
      2013 Final Research Report
  • [Journal Article] 全身疾患と弁膜症2013

    • Author(s)
      安隆則
    • Journal Title

      鄭忠和編集最新医学別冊「弁膜疾患」

      Pages: 230-233

    • Related Report
      2013 Final Research Report
  • [Journal Article] Dihydropyridine calcium channel blockers inhibit free fatty acid-induced endothelial and rheological dysfunction.2013

    • Author(s)
      Yasu T, Kobayashi M, Matsushita A, Yamakawa K, Momomura S, Ueda S.
    • Journal Title

      Clin Sci

      Volume: 125 Pages: 247-255

    • Related Report
      2013 Annual Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Clinical significance of plasma apolipoprotein F in Japanese healthy and hypertriglyceridemic subjects.2013

    • Author(s)
      Kujiraoka T, Nakamoto T, Sugimura H, Iwasaki T, Ishihara M, Hoshi T, Horie Y, Ogawa K, Todoroki M, Nakatani Y, Banba N, Yasu T, Hattori H.
    • Journal Title

      J Atheroscler Thromb

      Volume: 20 Pages: 380-390

    • NAID

      130004444670

    • Related Report
      2013 Annual Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 虚血性心疾患の疾病管理プログラムとしての外来型心臓リハビリテーションの効果と普及方策に関する研究」(J-REHAB)分担研究報告書2013

    • Author(s)
      安 隆則
    • Journal Title

      厚生労働科学研究費補助金(循環器疾患・糖尿病等生活習慣病対策総合研究事業 後藤班)報告書

      Volume: なし Pages: 40-40

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Contrast echocardiography for the diagnosis of left ventricular thrombus in anterior myocardial infarction.2013

    • Author(s)
      Wada H, Yasu T, Sakakura K, Hayakawa Y, Ishida T, Kobayashi N, Kubo N, Ako J, Momomura S.
    • Journal Title

      Heart and Vessels

      Volume: 印刷中

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 薬剤性心筋障害と弁膜症2013

    • Author(s)
      栗原明日香、安 隆則
    • Journal Title

      循環器内科

      Volume: 73 Pages: 487-493

    • NAID

      40019684486

    • Related Report
      2012 Research-status Report
  • [Journal Article] 末梢動脈疾患の心血管リハビリテーション2012

    • Author(s)
      安隆則
    • Journal Title

      日本下肢救済・足病学会誌

      Volume: 4 Pages: 113-116

    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Journal Article] C反応性蛋白2012

    • Author(s)
      安隆則
    • Journal Title

      Heart View

      Volume: 16 Pages: 153-156

    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Journal Article] PADの心血管リハビリテーション2012

    • Author(s)
      安隆則
    • Journal Title

      Heartナース

      Volume: 9 Pages: 880-885

    • Related Report
      2013 Final Research Report
  • [Journal Article] 薬剤性心筋障害2012

    • Author(s)
      安隆則
    • Journal Title

      医学のあゆみ

      Volume: 242 Pages: 267-268

    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Journal Article] PADの心血管リハビリテーション2012

    • Author(s)
      安 隆則
    • Journal Title

      Heart

      Volume: 9 Pages: 880-885

    • Related Report
      2012 Research-status Report
  • [Journal Article] Effects of thiazolidinediones on in-stent restenosis : a review of IVUS studies2011

    • Author(s)
      Yasu T, Katayama T, Ueba H, Kawakami M
    • Journal Title

      Intravascular Ultrasound

      Pages: 151-157

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] 末梢動脈疾患・虚血性心疾患の低身体活動患者では食事療法および運動療法の啓発とその実践が重要である2014

    • Author(s)
      南部路治, 安 隆則, 大屋祐輔, 他
    • Organizer
      第78回日本循環器学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Effects of exercise after administration of heparin and lipo-PGE1 for patients with peripheral arterial disease2014

    • Author(s)
      Yasu T, et al
    • Organizer
      第78回日本循環器学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of exercise after administration of heparin and lipo-PGE1 for patients with peripheral arterial disease.2014

    • Author(s)
      Yasu T
    • Organizer
      第78回日本循環器学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 会長講演血液流動性試験と微小循環2013

    • Author(s)
      安隆則
    • Organizer
      第20回日本ヘモレオロジー学会
    • Place of Presentation
      栃木
    • Related Report
      2013 Final Research Report
  • [Presentation] 血液流動性試験と微小循環2013

    • Author(s)
      安 隆則
    • Organizer
      第20回日本ヘモレオロジー学会
    • Place of Presentation
      栃木
    • Related Report
      2013 Annual Research Report
  • [Presentation] ラウンドテーブルディスカッション「末梢動脈疾患に対する包括的リハビリテーション普及に向けて」2012

    • Author(s)
      安隆則
    • Organizer
      第76回日本循環器学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation]2012

    • Author(s)
      小林真由美, 安隆則, 相澤直輝, 池宮城秀一, 大城克彦, 伊敷哲也, 石田明夫, 中元隆明, 大屋祐輔
    • Organizer
      日本ヘモレオロジー学会
    • Place of Presentation
      神戸
    • Related Report
      2013 Final Research Report
  • [Presentation] レニン・アンジオテンシン系阻害薬は脂肪負荷ヒトモデルにおける反応性充血時の心筋微小循環不全を改善する2012

    • Author(s)
      安隆則, 小林真由美, 松下明子, 和田浩, 菊池佑二, 植田真一郎
    • Organizer
      日本ヘモレオロジー学会
    • Place of Presentation
      神戸
    • Related Report
      2013 Final Research Report
  • [Presentation] PAD運動療法2012

    • Author(s)
      南部路治, 安隆則
    • Organizer
      心臓リハビリテーション学会
    • Related Report
      2013 Final Research Report
  • [Presentation] 日本人下肢末梢動脈疾患患者の運動習慣に関する横断研究2011

    • Author(s)
      安隆則, 大城克彦, 伊敷哲也, 百村伸一, 荒尾憲司郎, 下山博身, 植田真一郎, 松岡悟, 島田和典, 領家勉, 西山安弘, 折口秀樹, 和気稔, 石川直樹, 梶原光嗣, 新里譲, 大屋祐輔
    • Organizer
      第17回心臓リハビリテーション学会
    • Place of Presentation
      大阪
    • Related Report
      2013 Final Research Report
  • [Presentation] 日本人下肢末梢動脈疾患患者の運動習慣に関する横断研究2011

    • Author(s)
      安 隆則、大城克彦、伊敷哲也、百村伸一、荒尾憲司郎、下山博身、植田真一郎、松岡 悟、島田 和典領家 勉、西山安弘、折口秀樹、和気 稔、石川直樹、梶原光嗣、 新里 譲、大屋祐輔
    • Organizer
      心臓リハビリテーション学会
    • Place of Presentation
      大阪国際会議場
    • Related Report
      2011 Research-status Report
  • [Presentation] 末梢動脈疾患に対する包括的リハビリテーション普及に向けて

    • Author(s)
      安 隆則
    • Organizer
      日本循環器学会
    • Place of Presentation
      福岡県
    • Related Report
      2012 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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