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Development of neurofeedback therapy for post-stroke hemiplegic upper limbs and verification of its effects

Research Project

Project/Area Number 23500630
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKio University

Principal Investigator

MORIOKA Shu  畿央大学, 健康科学部, 教授 (20388903)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordsニューロフィードバック / 脳機能イメージング / 脳卒中 / リハビリテーション / 上肢機能 / 片麻痺 / 脳活動 / イメージ / NIRS / EEG
Research Abstract

In this study, we initially investigated tool operation and motor-related brain activity in normal subjects during observation and motor imagery by using an NIRS-EEG system. A standard threshold was set based on the brain activity recorded. We also developed a neurofeedback device, which can give visual feedback when the threshold is exceeded. Because activity was clearer in the left premotor cortex in all subjects, we focused on activity in that area. A 2-week intervention was conducted using this device for 10 subjects with upper limb motor deficit following stroke. This intervention significantly improved function in six subjects with activity surpassing the threshold in the left premotor cortex during tool operation observation and motor imagery. On the other hand, intervention did not have a marked effect in four subjects who showed brain activity below the threshold.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (53 results)

All 2014 2013 2012 2011 Other

All Journal Article (19 results) (of which Peer Reviewed: 16 results) Presentation (20 results) (of which Invited: 1 results) Book (9 results) Remarks (5 results)

  • [Journal Article] Brain activity and the perception of self-agency while viewing a video of tool manipulation : a functional near-infrared spectroscopy study2014

    • Author(s)
      Wakata S, Morioka S
    • Journal Title

      Neuroreport

      Volume: 25 Pages: 422-426

    • Related Report
      2013 Final Research Report
  • [Journal Article] Brain activity and the perception of self-agency while viewing a video of tool manipulation: a functional near infrared spectroscopy study2014

    • Author(s)
      Wakata S. Morioka S.
    • Journal Title

      Neuroreport

      Volume: 25 Issue: 6 Pages: 422-426

    • DOI

      10.1097/wnr.0000000000000131

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in electroencephalographic activity during observation, preparation, and execution of a motor learning task2013

    • Author(s)
      Nakano H, Osumi M, Ueta K, Kodama T, Morioka S
    • Journal Title

      Int J Neurosci

      Volume: 123 Pages: 866-75

    • Related Report
      2013 Final Research Report
  • [Journal Article] Changes in electroencephalographic activity during observation, preparation, and execution of a motor learning task.2013

    • Author(s)
      Nakano H, Osumi M, Ueta K, Kodama T. Morioka S
    • Journal Title

      International Journal of Neuroscience

      Volume: 123 Issue: 12 Pages: 866-875

    • DOI

      10.3109/00207454.2013.813509

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of a plantar perceptual learning task on walking stability in the elderly : a randomized controlled trial.2013

    • Author(s)
      Nakano H, Nozaki M, Ueta K, Osumi M. Kawami S. Morioka S
    • Journal Title

      Clinical Rehabilitation

      Volume: 27 Issue: 7 Pages: 608-615

    • DOI

      10.1177/0269215512471062

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Brain Activity during the Observation, Imagery, and Execution of Tool Use : An Fnirs/EEG Study2012

    • Author(s)
      Nakano H, Ueta K, Osumi M, Morioka S
    • Journal Title

      J Nov Physiother

      Volume: S1 Pages: 9-9

    • Related Report
      2013 Final Research Report
  • [Journal Article] Brain activity during the observation, imagery, and execution of tool use : an fNIRS/EEG study2012

    • Author(s)
      Nakano H, Ueta K, Osumi M, Morioka S
    • Journal Title

      Journal of Novel Physiotherapies

      Volume: 2012, S1 Issue: S1

    • DOI

      10.4172/2165-7025.s1-009

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Influence of a plantar perceptual learning task on brain activity: fNIRS study2012

    • Author(s)
      Nakano H, Miki K, Osumi M, Ueta K, Kawami S, Morioka S
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 24 Pages: 711-713

    • NAID

      10031127048

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Changes in the equilibrium of standing on one leg at various life stages.2012

    • Author(s)
      Morioka S, Fukumoto T, Hiyamizu M, Matsuo A, Takebayashi H, Miyamoto K.
    • Journal Title

      Current Gerontology and Geriatrics Research

      Volume: 2012 Pages: 1-6

    • DOI

      10.1155/2012/516283

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Brain activity stimulated by prism adaptation tasks utilized for the treatment of unilateral spatial neglect: A study with fNIRS2012

    • Author(s)
      Taniguchi H, Hiyamizu M, Tominaga T, Morioka S
    • Journal Title

      Rehabilitation Research and Practice

      Volume: 2012 Pages: 1-6

    • DOI

      10.1155/2012/312781

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effectiveness of the gaze direction recognition task for chronic neck pain and cervical range of motion: a randomized controlled pilot study2012

    • Author(s)
      Nobusako S, Matsuo A, Morioka S
    • Journal Title

      Rehabilitation Research and Practice

      Volume: 2012 Pages: 1-13

    • DOI

      10.1155/2012/570387

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 物体の視覚的提示に伴う腱振動刺激による運動錯覚時の脳活動 fNIRS研究2012

    • Author(s)
      今井亮太,中野英樹,森岡 周
    • Journal Title

      理学療法科学

      Volume: 27 Pages: 401-405

    • NAID

      10031077247

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of dual task balance training on dual task performance in elderly people: a randomized controlled trial2012

    • Author(s)
      Hiyamizu M, Morioka S, Shomoto K, Shimada T.
    • Journal Title

      Clin Rehabil

      Volume: 26 Issue: 1 Pages: 58-67

    • DOI

      10.1177/0269215511431921

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Influence of transcranial direct current stimulation of the dorsolateral prefrontal cortex on pain related emotions: A study using electroencephalographic power spectrum analysis.2012

    • Author(s)
      Maeoka H, Matsuo A, Hiyamizu M, Morioka S, Ando H.
    • Journal Title

      Neurosci Lett

      Volume: 512 Issue: 1 Pages: 12-16

    • DOI

      10.1016/j.neulet.2012.01.037

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 脳卒中片麻痺患者における振動誘発運動感覚錯覚中の脳活動2012

    • Author(s)
      湯川喜裕,富永孝紀,河野正志,谷口博,森岡周
    • Journal Title

      作業療法

      Volume: 31 Pages: 41-51

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of plantar perception training on standing posture balance in the old old and the very old living in nursing facilities: a randomized controlled trial.2011

    • Author(s)
      Morioka S, Fujita H, Hiyamizu M, Maeoka H, Matsuo A.
    • Journal Title

      Clin Rehabil

      Volume: 25 Issue: 11 Pages: 1011-1020

    • DOI

      10.1177/0269215511426644

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Influence of plantar hardness discrimination training on center-of-gravity sway while standing on one leg: a randomized controlled trial.2011

    • Author(s)
      Nakano H, Miki K, Fujita H, Kawami S, Morioka S
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 23 Pages: 741-744

    • NAID

      10029928645

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 失行症におけるクロスモダルトランスファー課題による治療介入が到達把握運動に及ぼす効果2011

    • Author(s)
      大植 賢治, 平井 久美, 河野 正志, 富永 孝紀, 村田 高穂, 森岡 周
    • Journal Title

      理学療法科学

      Volume: 26 Pages: 711-716

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 模倣障害を呈した右片麻痺患者及び失語症患者における視覚情報と体性感覚情報の異種感覚情報の統合が模倣に与える影響~視覚遮蔽下模倣検査による検討~2011

    • Author(s)
      沖田学,宮本謙三,森岡周,八木文雄,椛秀人
    • Journal Title

      神経心理学

      Volume: 27 Pages: 79-86

    • NAID

      10029842596

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] The activity of the "when" pathway during visual motion2013

    • Author(s)
      Tsujimoto K, Morioka S
    • Organizer
      European Association for Vision and Eye Research
    • Place of Presentation
      Nice, France
    • Related Report
      2013 Final Research Report
  • [Presentation] Relationship between brain activity and sense of self-agency during kinesthetic illusory feeling induced by tool use : a functional near-infrared spectroscopy study2013

    • Author(s)
      Wakata S , Morioka S
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] The relationship between kinesthesia and physical functions and damage region in stroke hemiplegic patients2013

    • Author(s)
      Morioka S, Toyota Y, Yukawa Y, Matsuo A, Hiyamizu M, Maeoka H, Nobusako S
    • Organizer
      XXII European Stroke Conference
    • Place of Presentation
      London, UK
    • Related Report
      2013 Final Research Report
  • [Presentation] The relationship between kinesthesia and physical functions and damage region in stroke hemiplegic patients2013

    • Author(s)
      Morioka S, Toyota Y, Yukawa Y, Matsuo A, Hiyamizu M, Maeoka H, Nobusako S
    • Organizer
      22th European Stroke Conference
    • Place of Presentation
      London UK
    • Related Report
      2013 Annual Research Report
  • [Presentation] fNIRSによる脳活動の計測と高次脳機能2013

    • Author(s)
      森岡 周
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Brain activity during observation, imagery, and execution of tool use : An fNIRS-EEG study2012

    • Author(s)
      Nakano H, Ueta K, Osumi M, Morioka S
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of differences in stimulation of tool use-related functional knowledge and manipulation knowledge : An event-related potential study2012

    • Author(s)
      Wakata S, Morioka S
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Change of cortical activities during the preparation on gait2012

    • Author(s)
      Ueta K, Nobusako S, Fujita H, Morioka S
    • Organizer
      1st Joint World Congress of ISPGR and Gait & Mental Function
    • Place of Presentation
      Trondheim, Norway
    • Related Report
      2012 Research-status Report
  • [Presentation] Brain activity during observation, imagery, and execution of tool use: An fNIRS-EEG study2012

    • Author(s)
      Nakano H, Ueta K, Osumi M, Morioka S
    • Organizer
      46th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Effects of differences in stimulation of tool use-related functional knowledge and manipulation knowledge: An event-related potential study2012

    • Author(s)
      Wakata S, Morioka S
    • Organizer
      46th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Evaluation of the effect of change in walking condition on brain activity through electroencephalography2012

    • Author(s)
      Fujiwara N, Nakano H, Ueta K, Morioka S
    • Organizer
      46th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Outcomes of the ball-rotation task are indicated by the alpha power during action observation and action preparation2011

    • Author(s)
      Nakano H, Osumi M, Yonemoto Y, Kodama T, Morioka S
    • Place of Presentation
      Washington, DC, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Differences in brain activation while using a familiar tool, mimicking tool use by holding only the tool grip, and pantomiming tool use2011

    • Author(s)
      Wakata S, Morioka S
    • Place of Presentation
      Washington, DC, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] The effect of transcranial direct current-stimulated motor imagery on the excitability of the anterior horn cell of spinal cord2011

    • Author(s)
      Morioka S, Yoshikawa N, Matsuo A, Hiyamizu M, Maeoka H
    • Organizer
      14th European congress on Clinical Neurophysiology and 4th International Conference on Transcranial Magnetic and Direct Current Stimulation
    • Place of Presentation
      ローマ、イタリア
    • Related Report
      2011 Research-status Report
  • [Presentation] Influence of the brain activity in observation conditions on balance learning2011

    • Author(s)
      Hiyamizu M, Maeoka H, Matsuo A, Morioka S
    • Organizer
      14th European congress on Clinical Neurophysiology and 4th International Conference on Transcranial Magnetic and Direct Current Stimulation
    • Place of Presentation
      ローマ、イタリア
    • Related Report
      2011 Research-status Report
  • [Presentation] Brain activation on walking visual illusion2011

    • Author(s)
      Matsuo A, Ishikawa T, Fukui T , Hiyamizu M, Maeoka H, Morioka S
    • Organizer
      14th European congress on Clinical Neurophysiology and 4th International Conference on Transcranial Magnetic and Direct Current Stimulation
    • Place of Presentation
      ローマ、イタリア
    • Related Report
      2011 Research-status Report
  • [Presentation] Outcomes of the ball-rotation task are indicated by the alpha power during action observation and action preparation.2011

    • Author(s)
      Nakano H, Yonemoto Y, Osumi M, Kodama T, Morioka S
    • Organizer
      45th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      ワシントンD.C. USA
    • Related Report
      2011 Research-status Report
  • [Presentation] Differences in brain activation while using a familiar tool, mimicking tool use by holding only the tool grip, and pantomiming tool use.2011

    • Author(s)
      Satoshi Wakata, Shu Morioka
    • Organizer
      45th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      ワシントンD.C. USA
    • Related Report
      2011 Research-status Report
  • [Presentation] 脳科学からみた運動学習2011

    • Author(s)
      森岡周
    • Organizer
      第46回日本理学療法学術大会(招待講演)
    • Place of Presentation
      宮崎、日本
    • Related Report
      2011 Research-status Report
  • [Presentation] ニューロリハビリテーションと脳の機能的イメージング2011

    • Author(s)
      森岡周
    • Organizer
      第27回東海北陸理学療法学術大会(招待講演)
    • Place of Presentation
      富山、日本
    • Related Report
      2011 Research-status Report
  • [Book] 脳を学ぶ-「ひと」とその社会がわかる生物学2014

    • Author(s)
      森岡周
    • Total Pages
      144
    • Publisher
      協同医書出版社
    • Related Report
      2013 Final Research Report
  • [Book] リハビリテーションのための神経生物学入門2013

    • Author(s)
      森岡周
    • Total Pages
      366
    • Publisher
      協同医書出版社
    • Related Report
      2013 Final Research Report
  • [Book] リハビリテーションのための神経生物学入門2013

    • Author(s)
      森岡 周
    • Total Pages
      362
    • Publisher
      協同医書出版社
    • Related Report
      2012 Research-status Report
  • [Book] 神経理学療法学2013

    • Author(s)
      吉尾雅春,森岡 周
    • Total Pages
      397
    • Publisher
      医学書院
    • Related Report
      2012 Research-status Report
  • [Book] イメージの科学2012

    • Author(s)
      森岡 周,松尾 篤
    • Total Pages
      269
    • Publisher
      三輪書店
    • Related Report
      2012 Research-status Report
  • [Book] Infrared Spectroscopy / Book 12012

    • Author(s)
      Morioka S, et al
    • Total Pages
      368
    • Publisher
      InTech
    • Related Report
      2011 Research-status Report
  • [Book] 脳を学ぶ(3)2011

    • Author(s)
      森岡周、他
    • Total Pages
      139
    • Publisher
      協同医書出版社
    • Related Report
      2011 Research-status Report
  • [Book] ペインリハビリテーション2011

    • Author(s)
      松原貴子、沖田実、森岡周
    • Total Pages
      411
    • Publisher
      三輪書店
    • Related Report
      2011 Research-status Report
  • [Book]

    • Author(s)
      森岡周, 吉尾雅春(編著)
    • Related Report
      2013 Final Research Report
  • [Remarks]

    • URL

      http://www.kio-neuroreha.com/

    • Related Report
      2013 Final Research Report
  • [Remarks] 畿央大学ニューロリハビリテーション研究センター

    • URL

      http://www.kio.ac.jp/nrc/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 畿央大学ニューロリハビリテーション研究室

    • URL

      http://www.kio-neuroreha.com

    • Related Report
      2013 Annual Research Report
  • [Remarks] 畿央大学ニューロリハビリテーション研究室

    • URL

      http://www.kio-neuroreha.com

    • Related Report
      2012 Research-status Report
  • [Remarks] 畿央大学ニューロリハビリテーション研究センター

    • URL

      http://www.kio.ac.jp/nrc/

    • Related Report
      2012 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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