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Therapeutic effect of repetitive transcranial magnetic stimulation in chronic aphasia patients and brain activation patterns

Research Project

Project/Area Number 23500633
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionUniversity of Occupational and Environmental Health, Japan

Principal Investigator

OKAZAKI Tetsuya  産業医科大学, 医学部, 講師 (40352314)

Co-Investigator(Kenkyū-buntansha) HACHISUKA Kenji  産業医科大学, 医学部, 教授 (00129602)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords反復経頭蓋磁気刺激 / 失語症 / 近赤外線分光法 / 近赤外分光法
Research Abstract

We applied inhibitory repetitive transcranial magnetic stimulation (rTMS) to right-hemisphere Broca's homologue daily, for 10 days in chronic aphasia patients. Although improvement of aphasia was admitted in a descriptive observation, standard language test showed no significant improvement after rTMS treatments, Laterality index, which obtained by near-infrared spectroscopic mapping, revealed most patients demonstrate right dominance brain activation during picture naming task. Then, change in laterality index before and after rTMS treatments did not show uniform trend.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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